Top Senior IT Jobs in St. Louis, MO

21 Days AgoSaved
Hybrid
St. Louis, MO
191K-259K Annually
Senior level
191K-259K Annually
Senior level
Aerospace • Information Technology • Software • Cybersecurity • Design • Defense • Manufacturing
Lead IT teams at Boeing Global Services, managing technical projects and relationships while striving for process improvements and aligning IT goals with business objectives.
Top Skills: Computing SecurityDigital TransformationInformation TechnologyInfrastructure Design
21 Days AgoSaved
Hybrid
St. Louis, MO
133K-181K Annually
Senior level
133K-181K Annually
Senior level
Aerospace • Information Technology • Software • Cybersecurity • Design • Defense • Manufacturing
The Senior IT Business Operations Chief of Staff will support strategic leadership and oversee operations, ensuring program delivery and stakeholder alignment across the Boeing Defense Systems CIO Organization.
Top Skills: ComplianceDigitalInformation TechnologyProgram ManagementRisk Management
Reposted 6 Days AgoSaved
Hybrid
St. Louis, MO
99K-297K Annually
Senior level
99K-297K Annually
Senior level
Artificial Intelligence • Professional Services • Business Intelligence • Consulting • Cybersecurity • Generative AI
Manage IT controls auditing and consulting, ensuring compliance with regulations, mentoring teams, and engaging with clients to enhance technology trust.
Top Skills: Ai SystemsCobitCoso FrameworkCyber SecurityData SystemsIt Controls AuditingItil
Reposted 55 Minutes AgoSaved
Remote or Hybrid
St. Louis, MO
100K-155K Annually
Senior level
100K-155K Annually
Senior level
Cloud • Computer Vision • Information Technology • Sales • Security • Cybersecurity
As a Lead Mobile Developer, you will design and maintain iOS apps, mentor developers, optimize performance, and integrate with backend services while collaborating with cross-functional teams.
Top Skills: Android SdkCombineCore DataGradleJetpackKotlinSwiftSwiftuiUikitXcode
Reposted 3 Days AgoSaved
Remote
St. Louis, MO
95K-112K Hourly
Senior level
95K-112K Hourly
Senior level
Computer Vision • Healthtech • Information Technology • Logistics • Machine Learning • Software • Manufacturing
Lead and execute remote technical implementations for dental practices from signing through go-live. Configure PMS integrations, set up remote access and network configurations, manage AWS-hosted Windows VMs/ETL, handle support volume, liaise with MSPs, and improve onboarding processes and automation while partnering with cross-functional teams.
Top Skills: AnydeskAWSCodentCurveDental Imaging SoftwareDenticonDentrixEaglesoftETLIntraoral Scanner PlatformsOpen DentalRemotepcSplashtopTeamviewerWindows Server
12 Days AgoSaved
In-Office
St. Louis, MO
104K-140K Annually
Senior level
104K-140K Annually
Senior level
Aerospace • Information Technology • Software • Cybersecurity • Design • Defense • Manufacturing
Support deployment, integration, and lifecycle maintenance of COTS engineering and enterprise applications across cloud and on‑prem environments. Define/validate requirements, design and test systems, perform trade studies, develop processes and integration strategies, ensure licensing compliance, and maintain configuration management documentation for proprietary programs.
Top Skills: CloudConfiguration Management Database (Cmdb)CotsDevsecopsEnterprise Resource Planning (Erp)Manufacturing Operations Management (Mom)On-PremProduct Lifecycle Management (Plm)Vendor Integration
Reposted 12 Days AgoSaved
Hybrid
St. Louis, MO
162K-219K Annually
Senior level
162K-219K Annually
Senior level
Aerospace • Information Technology • Software • Cybersecurity • Design • Defense • Manufacturing
The Senior Manager will lead cybersecurity risk management for classified infrastructures, focusing on strategic leadership while overseeing organizational plans and improving processes.
Top Skills: AcasAudit ReductionCnssi 1253DaapmDisa StigsHbssIcd-503JsigNessusNist Sp 800 SeriesRisk Management FrameworkScap
Reposted 4 Days AgoSaved
Remote or Hybrid
St. Louis, MO
115K-130K Annually
Senior level
115K-130K Annually
Senior level
AdTech • Consumer Web • Digital Media • eCommerce • Marketing Tech
The Senior IT Infrastructure Engineer will enhance automation and integration efforts while managing cloud services, CI/CD pipelines, and Kubernetes operations.
Top Skills: AnsibleArgo CdAWSAzureCrossplaneDaggerDockerGCPGitGoGrafanaHelmJavaScriptJenkinsKubernetesN8NPrometheusPythonRestSoapTerraformTypescript
Reposted 9 Days AgoSaved
Remote
St. Louis, MO
111K-178K Annually
Senior level
111K-178K Annually
Senior level
Cloud • Fintech • Food • Information Technology • Software • Hospitality
The IT Delivery Manager is responsible for overseeing IT programs, coordinating cross-functional initiatives, managing user experiences, defining success metrics, and serving as a liaison between technical teams and business stakeholders.
Top Skills: AgileHexItilJIRAKanbanOktaPower BISailpointServicenowSnowflakeWaterfall
10 Days AgoSaved
Easy Apply
Remote
St. Louis, MO
Easy Apply
166K-196K Annually
Senior level
166K-196K Annually
Senior level
Artificial Intelligence • Blockchain • Fintech • Financial Services • Cryptocurrency • NFT • Web3
Lead and coordinate IT and security audits across cloud infrastructure, application security, IAM, vendor risk, and blockchain products; shape audit roadmap; produce executive- and Board-level reports; drive remediation and validate corrective actions; partner with technology leaders and mentor audit staff.
Top Skills: AWSBlockchainCloud InfrastructureCobitCold StorageEncryptionGCPGenerative AiIamItilLoggingNetwork ArchitectureNist CsfSoc 2Wallets
10 Days AgoSaved
Easy Apply
Remote
St. Louis, MO
Easy Apply
131K-154K Annually
Senior level
131K-154K Annually
Senior level
Artificial Intelligence • Blockchain • Fintech • Financial Services • Cryptocurrency • NFT • Web3
Lead end-to-end IT and security audits across cloud infrastructure, application security, IAM, vendor risk, and blockchain products. Plan and execute fieldwork, produce evidence-based reports for senior leaders and the Audit Committee, mentor junior auditors, validate remediation, and partner with Engineering and Security to improve controls while maintaining audit independence.
Top Skills: AWSBlockchainCobitCold StorageEncryptionGCPGenerative AiIdentity And Access Management (Iam)ItilLoggingNetwork ArchitectureNist CsfSoc 2Wallets
11 Days AgoSaved
Easy Apply
Remote
St. Louis, MO
Easy Apply
201K-237K Annually
Senior level
201K-237K Annually
Senior level
Artificial Intelligence • Blockchain • Fintech • Financial Services • Cryptocurrency • NFT • Web3
Lead Coinbase's global IT and security audit program, delivering complex cross-functional audits across cloud, infrastructure, cybersecurity, IAM, data protection, and third-party risk. Manage and develop a global audit team, partner with first- and second-line stakeholders to drive integrated assurance, and report executive-level findings to senior leadership and the Audit Committee. Modernize audit execution through data analytics, automation, and generative AI to enable continuous monitoring and automated evidence retrieval.
Top Skills: AutomationCloud InfrastructureCloud Security ConfigurationsCobitContinuous MonitoringData AnalyticsData ProtectionGenerative AiIdentity And Access ManagementItilNistSecurity OperationsSoftware Development Lifecycle (Sdlc)Third-Party/Vendor Risk Management
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Reposted 5 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Cloud • Information Technology • Internet of Things
The Senior Solutions Architect II leads the design and implementation of large-scale solutions, drives innovation, and mentors team members. They also collaborate on pre-sales with Sales teams and serve as technical escalation points for complex issues.
Top Skills: Active Directory Certificate ServicesActive Directory Federation ServicesComputer ScienceInformation TechnologyLinuxMicrosoft 365PkiPowershellPublic-Key InfrastructureSQLUnix
Reposted 5 Days AgoSaved
Remote
St. Louis, MO
100K-125K Annually
Senior level
100K-125K Annually
Senior level
Insurance
The Senior IT Auditor independently conducts IT audits, assessing controls, reporting deficiencies, and ensuring compliance with standards. Requires strong communication and organizational skills.
Top Skills: Cyber SecurityInformation TechnologyInternal ControlsSox
Reposted 10 Days AgoSaved
Remote
St. Louis, MO
206K-216K Annually
Senior level
206K-216K Annually
Senior level
Fintech
Support risk assessment, audit planning, and oversight of audit management and staff. Provide advisory services and ensure compliance with standards.
Top Skills: Cloud TechnologiesComputer ScienceCybersecurityData ScienceEnterprise Data ManagementIdentity And Access ManagementInformation Technology
Reposted 14 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Healthtech
The Lead Technical Support Engineer resolves complex technical issues, provides mentorship, collaborates with teams, and improves support systems.
Top Skills: AWSAzureComputer ScienceInformation TechnologyPowershellServicenow
Reposted 2 Days AgoSaved
In-Office or Remote
St. Louis, MO
118K-197K Annually
Senior level
118K-197K Annually
Senior level
Healthtech
The role involves leading the data governance team, managing IT projects, collaborating with stakeholders, and ensuring continuous improvement of processes. Responsibilities include strategic planning, client management, and optimizing resource utilization, while overseeing governance activities and departmental management.
Top Skills: Application Software Development ManagementData GovernanceData Marketplace
3 Days AgoSaved
In-Office
St. Louis, MO
71K-137K Annually
Senior level
71K-137K Annually
Senior level
Greentech • Hardware • Energy
Plan and execute IT audits of digital systems, cybersecurity, data privacy, change management and SOX controls. Assess risks, report findings, support remediation, collaborate with management and external auditors, and assist on project/process control reviews.
Top Skills: Oracle
Reposted 16 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Information Technology • Consulting
The role involves developing, testing, and maintaining computer programs, supporting complex analyses, managing development efforts, and ensuring alignment with organizational methodologies.
Top Skills: AgileAws GovcloudDevsecopsInformation Technology
Reposted 16 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Information Technology • Consulting
The Technical Project Manager oversees IT project planning, execution, and delivery within the government sector, ensuring stakeholder coordination and compliance with regulations.
Top Skills: Agile MethodologiesAws GovcloudIdentity And Access ManagementInformation Technology
Reposted 16 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Information Technology • Consulting
The Test Manager designs and executes comprehensive testing processes, manages testing events, oversees engineering activities, ensures effective schedule and resource allocation, and maintains quality assurance for large-scale systems integration.
Top Skills: Aws GovcloudIdentity And Access ManagementInformation Technology
Reposted 17 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Information Technology
The Sr. Project Manager is responsible for delivering technical projects, managing resources, and updating stakeholders while focusing on onboarding new clients.
Top Skills: Audiovisual SystemsCloud IntegrationsConstructionInformation TechnologyProject Management Software
Reposted 5 Days AgoSaved
In-Office
St. Louis, MO
Senior level
Senior level
Fintech • Analytics
The role involves managing application services, driving improvements, handling incidents, and leveraging domain knowledge to enhance service quality and efficiency.
Top Skills: DatadogItrs
9 Days AgoSaved
In-Office
St. Louis, MO
Senior level
Senior level
AdTech
Lead and develop onboarding and support teams for the Retail Performance Platform (RPP). Oversee end-to-end client onboardings, production support, incident management, and cross-functional alignment with Engineering and Product. Drive process improvements, staffing, performance management, and operational strategy to scale the platform and ensure client satisfaction.
Top Skills: Ai-Enabled ToolsCloud-Native PlatformsMulti-Tenant ArchitecturesRetail Performance Platform (Rpp)
Reposted 45 Minutes AgoSaved
Remote
St. Louis, MO
125K-175K Annually
Senior level
125K-175K Annually
Senior level
Insurance
The Director of IT Applications leads the delivery of enterprise applications, ensuring that business systems effectively support operations across Finance, Sales, Marketing, HR, and more while driving automation and system improvements.
Top Skills: ConfluenceJIRAOracle NetsuiteSalesforceServicenow
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