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Top Senior IT Jobs in St. Louis, MO

2 Days AgoSaved
In-Office
St. Louis, MO
133K-193K Annually
Senior level
133K-193K Annually
Senior level
Aerospace • Information Technology • Software • Cybersecurity • Design • Defense • Manufacturing
The Senior Information Technology Chief of Staff will support an executive director, manage strategic priorities, oversee operations, and ensure alignment across stakeholders.
Top Skills: M365
3 Days AgoSaved
In-Office
St. Louis, MO
133K-181K Annually
Senior level
133K-181K Annually
Senior level
Aerospace • Information Technology • Software • Cybersecurity • Design • Defense • Manufacturing
The Senior IT Product Owner will manage the infrastructure modernization backlog, ensuring alignment with operational priorities and strategic objectives while leading Agile execution practices and cross-functional coordination.
Top Skills: AgileItilJIRA
10 Days AgoSaved
In-Office
St. Louis, MO
104K-171K Annually
Senior level
104K-171K Annually
Senior level
Aerospace • Information Technology • Software • Cybersecurity • Design • Defense • Manufacturing
The IT Engineer will enhance hardware infrastructure, configure networks, update systems, manage hardware assets, and ensure compliance for software products in the GVHMS team.
Top Skills: Active DirectoryLinuxOracle DatabasePl/SqlPostgresVMwareWindows
Reposted 2 Days AgoSaved
Remote or Hybrid
St. Louis, MO
100K-155K Annually
Senior level
100K-155K Annually
Senior level
Cloud • Computer Vision • Information Technology • Sales • Security • Cybersecurity
As a Sr. Engineer, you will develop and customize Salesforce applications, support integration, troubleshoot issues, and mentor team members while ensuring product quality in Order to Cash solutions.
Top Skills: ApexAuraLightning Web ComponentsSalesforceVisualforce
Reposted 3 Days AgoSaved
Easy Apply
Remote
St. Louis, MO
Easy Apply
152K-179K Annually
Senior level
152K-179K Annually
Senior level
Artificial Intelligence • Blockchain • Fintech • Financial Services • Cryptocurrency • NFT • Web3
The Site Reliability Engineer will enhance CI/CD frameworks, automate cloud infrastructure, manage Kubernetes and AWS services, and ensure operational excellence.
Top Skills: AnsibleAWSBashChefCi/CdDockerGitKubernetesPuppetPythonRubySaltTerraform
Reposted 2 Days AgoSaved
Easy Apply
Remote
St. Louis, MO
Easy Apply
Senior level
Senior level
Security • Cybersecurity
The Senior IT Auditor leads PCI DSS assessments, manages client relationships, mentors juniors, and provides project status reports, ensuring high-quality service.
Top Skills: Audit Management TechnologyInformation SecurityInformation TechnologyPci Dss
Reposted 12 Days AgoSaved
Easy Apply
Remote
St. Louis, MO
Easy Apply
167K-197K Annually
Senior level
167K-197K Annually
Senior level
Artificial Intelligence • Blockchain • Fintech • Financial Services • Cryptocurrency • NFT • Web3
Drive IT SOX initiatives, lead assessments, create training, oversee audits, manage stakeholder relationships, and recommend solutions for compliance activities.
Top Skills: AWSCism)CisspSecurity Certifications (Cisa
Reposted 13 Days AgoSaved
Easy Apply
Remote
St. Louis, MO
Easy Apply
186K-219K Annually
Senior level
186K-219K Annually
Senior level
Artificial Intelligence • Blockchain • Fintech • Financial Services • Cryptocurrency • NFT • Web3
The role involves supporting network infrastructure, automating cloud infrastructure, managing CI/CD workflows, and ensuring operational excellence in IT support, including incident response and security practices.
Top Skills: AnsibleAWSBashDockerGitKubernetesPythonRubyTerraform
14 Days AgoSaved
Easy Apply
Remote
St. Louis, MO
Easy Apply
144K-199K Annually
Senior level
144K-199K Annually
Senior level
Artificial Intelligence • Fintech • Machine Learning • Social Impact • Software
Manage IT projects from concept to deployment, focusing on scalable systems, endpoint management, identity access, and SaaS operations to enhance employee tech experience.
Top Skills: Aws CdkAws Ec2Aws S3Google WorkspaceiOSJAMFmacOSOktaTerraformZoom
17 Days AgoSaved
Easy Apply
Remote
St. Louis, MO
Easy Apply
166K-196K Annually
Senior level
166K-196K Annually
Senior level
Artificial Intelligence • Blockchain • Fintech • Financial Services • Cryptocurrency • NFT • Web3
Manage end-to-end delivery of IT audits, focusing on cloud infrastructure and security operations while driving AI-enabled audit execution and reporting.
Top Skills: Ai-Enabled WorkflowsAutomationAWSCobitData AnalyticsGCPGenerative AiIam PoliciesItilNist CsfPythonSoc 2SQL
17 Days AgoSaved
Easy Apply
Remote
St. Louis, MO
Easy Apply
201K-237K Annually
Senior level
201K-237K Annually
Senior level
Artificial Intelligence • Blockchain • Fintech • Financial Services • Cryptocurrency • NFT • Web3
Lead the strategic direction for IT and security audits at Coinbase, managing a global team to ensure compliance with regulations and enhance technology controls across regions.
Top Skills: Cloud TechnologyCobitCybersecurityData ProtectionGenerative Ai ToolsGrc PlatformsInternal AuditIt AuditingItil)Risk Management Frameworks (NistSoftware Development Lifecycles
Reposted 13 Days AgoSaved
Remote
St. Louis, MO
93K-125K Annually
Senior level
93K-125K Annually
Senior level
Big Data • Cloud • Information Technology
The Senior Global Account Manager will drive growth in Asset Lifecycle Management by building strategic accounts, leading hardware transitions, and influencing C-Suite stakeholders.
Top Skills: Asset Lifecycle ManagementInformation TechnologyReverse Logistics
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17 Days AgoSaved
Remote
St. Louis, MO
125K-155K Annually
Senior level
125K-155K Annually
Senior level
Healthtech
The Sr. Legal Risk Manager oversees the Third-Party Risk Management program, ensuring compliance with regulations, managing vendor relationships, and safeguarding information assets against cyber threats.
Top Skills: CybersecurityEhr/Emr SystemsExcelForm AssemblyGoogle SheetsHitrustInformation TechnologyMonday.ComNist
Reposted 5 Days AgoSaved
In-Office
St. Louis, MO
76K-129K Annually
Senior level
76K-129K Annually
Senior level
Financial Services
Supervise and perform procedures for IT General Controls in SOX and Internal Audit engagements, mentor staff, and manage client relationships.
Top Skills: Adobe Acrobat EngagementMicrosoft Office SuiteSAP
Reposted 19 Days AgoSaved
Remote
St. Louis, MO
206K-216K Annually
Senior level
206K-216K Annually
Senior level
Fintech
Support risk assessment, audit planning, and oversight of audit management and staff. Provide advisory services and ensure compliance with standards.
Top Skills: Cloud TechnologiesComputer ScienceCybersecurityData ScienceEnterprise Data ManagementIdentity And Access ManagementInformation Technology
Reposted 6 Days AgoSaved
Hybrid
St. Louis, MO
94K-94K Annually
Senior level
94K-94K Annually
Senior level
Payments
Lead requirements analysis, design, and delivery of Cass TIS solutions. Document requirements, conduct gap analysis, define acceptance criteria, coordinate teams, create project plans, and mentor junior analysts to ensure successful deployments.
Top Skills: Cass TisExcelMicrosoft Sql ServerMicrosoft VisioMicrosoft Word
Reposted 22 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Healthtech
The Lead Technical Support Engineer resolves complex technical issues, provides mentorship, collaborates with teams, and improves support systems.
Top Skills: AWSAzureComputer ScienceInformation TechnologyPowershellServicenow
2 Hours AgoSaved
Remote
St. Louis, MO
111K-166K Annually
Senior level
111K-166K Annually
Senior level
Energy • Utilities
The Senior Procurement Manager will oversee IT sourcing and software procurement, manage renewals, drive savings, and mentor team members in procurement practices.
Top Skills: Contract ManagementIt SourcingProject ManagementRoi AnalysisSoftware ProcurementSpreadsheets
Reposted 3 Hours AgoSaved
Remote
St. Louis, MO
90K-130K Annually
Senior level
90K-130K Annually
Senior level
Healthtech
Oversee and manage technical IT projects, ensuring they meet goals and objectives. Collaborate with stakeholders, develop project plans, and facilitate communication across teams.
Top Skills: ClarityJIRAMS OfficeMs ProjectPlanviewServicenow PpmVisio
4 Hours AgoSaved
Easy Apply
Remote
St. Louis, MO
Easy Apply
136K-178K Annually
Senior level
136K-178K Annually
Senior level
Healthtech
The Senior IT Engineer, AI Enablement integrates SaaS tools with Omada's MCP ecosystem, drives AI adoption, collaborates across teams, and ensures secure data handling while enhancing workflow automation.
Top Skills: McpOauthPythonRestSaaSWebhooks
Reposted 22 Hours AgoSaved
Remote
St. Louis, MO
160K-190K Annually
Senior level
160K-190K Annually
Senior level
Artificial Intelligence • Cybersecurity
Lead internal IT operations for a fast-growing remote cybersecurity company: define IT roadmap, scale infrastructure and team, manage ITSM/processes, own business application integrations, enforce security and compliance (SOC 2, ISO 27001, FedRAMP readiness), and provide hands-on escalation support for endpoints, networking, identity, and lifecycle management.
Top Skills: AbnormalCisco MerakiConfluenceDnsGoogle MeetGoogle WorkspaceIntuneIpaasJAMFJira AutomationsJira Service ManagementKandjimacOSMicrosoft Entra (Azure Ad)MimecastOffice 365OktaOkta Identity GovernanceOkta WorkflowsPowershellProofpointPythonScepScimSlackSublimeSuremdmWindowsZoomZoom Rooms
Reposted 22 Hours AgoSaved
Remote
St. Louis, MO
69K-90K Annually
Senior level
69K-90K Annually
Senior level
Information Technology
The IT Testing Engineer II is responsible for overseeing the software testing process, executing tests, managing defects, and collaborating with cross-functional teams to ensure software quality.
Top Skills: Automation TestingDefect Lifecycle ManagementSoftware TestingTest Case Development
Reposted 23 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Information Technology • Consulting
The role involves developing, testing, and maintaining computer programs, supporting complex analyses, managing development efforts, and ensuring alignment with organizational methodologies.
Top Skills: AgileAws GovcloudDevsecopsInformation Technology
Reposted 23 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Information Technology • Consulting
The Technical Project Manager oversees IT project planning, execution, and delivery within the government sector, ensuring stakeholder coordination and compliance with regulations.
Top Skills: Agile MethodologiesAws GovcloudIdentity And Access ManagementInformation Technology
Reposted 23 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Information Technology • Consulting
The Test Manager designs and executes comprehensive testing processes, manages testing events, oversees engineering activities, ensures effective schedule and resource allocation, and maintains quality assurance for large-scale systems integration.
Top Skills: Aws GovcloudIdentity And Access ManagementInformation Technology
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