Top Senior IT Jobs in St. Louis, MO

Designs, implements, and maintains automated security detection, orchestration, and integration capabilities for USPS. Analyzes security telemetry, identifies anomalies and detection gaps, enhances detection content, validates workflows, and supports SOC, threat intelligence, and incident response teams. The role also translates operational needs into technical solutions, researches emerging security and machine-learning capabilities, and maintains documentation, runbooks, and procedures.

Manages Safety and Compliance Committee operations, including member rosters, appointments, onboarding, training records, conflict-of-interest logs, SME coordination, SOP implementation, reporting, and meeting support. The role maintains accurate governance documentation, coordinates with HRSA, OPTN contractors, internal teams, and committee members, and ensures compliance with oversight requirements and established operational plans.

The Senior IT QA Engineer owns quality strategy and outcomes across complex technology initiatives. Responsibilities include designing automated testing solutions, integrating quality verification into CI/CD pipelines, analyzing quality and production data, developing dashboards, managing risk, leading root-cause analysis, and influencing product, engineering, architecture, security, operations, and business stakeholders. The role requires technical contributions across web, mobile, API, data, cloud, and distributed systems, plus mentoring engineers and advancing quality engineering practices.

Administer enterprise SharePoint Server and SharePoint Online environments, including configuration, permissions, governance, monitoring, migrations, backup and recovery, security, compliance, and troubleshooting. Automate administrative tasks with PowerShell and support integrations with Microsoft 365, Power Apps, and Power Automate. Maintain infrastructure involving Active Directory, IIS, SQL Server, and network load balancing. Document procedures, enforce change management, communicate technical concepts, and mentor junior staff.

Administers and governs enterprise Microsoft Power Platform environments across development, test, and production. Manages security, DLP policies, Dataverse, capacity, licensing, connectors, gateways, ALM, deployment pipelines, monitoring, and CoE operations. Develops governance standards, documentation, and reporting while troubleshooting platform issues and supporting compliance and change management. Collaborates with developers, architects, security teams, and business stakeholders, communicates technical concepts, and mentors junior staff.

Develop and maintain secure, scalable SharePoint Online solutions using SPFx, TypeScript, React, JavaScript, and Microsoft 365 integrations. Build reusable web parts and extensions, modernize legacy solutions, support migrations, troubleshoot performance and integration issues, manage testing and deployments, and document technical solutions. Collaborate with architects, administrators, developers, security teams, analysts, and stakeholders to translate business requirements into maintainable applications. Provide technical support and knowledge transfer while following accessibility, security, ALM, and development best practices.

Leads a Unix and Linux infrastructure team responsible for service delivery, operations, maintenance, incident resolution, and strategic project execution. Oversees technical strategy, modernization, automation, Agile delivery, ITIL practices, stakeholder communications, and continuous improvement. Manages recruitment, performance, training, mentoring, and professional development while guiding teams through complex technical and operational challenges. The role requires obtaining and maintaining a Public Trust and completing onsite fingerprinting.

Leads IT GxP and SOX compliance, FDA inspection readiness, audit response, remediation, and evidence management. Owns the IT technology portfolio, including prioritization, roadmap governance, dependencies, reporting, and launch-readiness programs. Coordinates IT governance, procurement, budgeting, policies, SOPs, steering cadences, and cross-functional delivery. Partners with quality, finance, legal, vendors, and managed-service teams to maintain compliant, inspection-ready IT operations across biotech systems.

Drive business growth across North American IT and SAP accounts. Manage client relationships, identify new and expansion opportunities, lead sales pitches, proposals, contract negotiations, and SOW execution. Coordinate offshore delivery alignment, engage executive stakeholders, and manage sales pipelines, account roadmaps, and revenue metrics. The role operates remotely from India during North American night-shift hours and requires strong IT services, SAP, and enterprise client experience.

Manage the company’s IT department and ensure reliable operation of networks, servers, systems, security, and end-user technology. Responsibilities include AWS and Oracle administration, Microsoft 365 access management, technical support, cybersecurity monitoring, compliance, vendor coordination, budgeting, and leading IT infrastructure projects. The role also supports Windows and Apple devices, manages IT tickets, and coordinates cross-functional technology initiatives.

Lead cybersecurity consulting and engineering engagements securing OT and IT environments for water, wastewater, and environmental infrastructure clients. Conduct ICS, SCADA, network, architecture, risk, and compliance assessments; design secure IT/OT architectures; develop governance, incident response, security plans, and improvement roadmaps; evaluate security technologies; and support proposals and client presentations. Mentor junior staff and advise on cloud, IoT, AI, and critical infrastructure security.

Leads the Order Management IT team, overseeing analysts and developers across custom applications and ERP initiatives. Owns delivery execution, milestone planning, risk mitigation, engineering quality, testing, CI/CD practices, and continuous improvement. Develops team members, manages staffing and performance, communicates delivery health to executives, and partners with product owners, architects, vendors, and business stakeholders to deliver supply chain technology solutions.

Writes, edits, and maintains policies, technical guides, standard operating procedures, and DoD compliance documentation for an Enterprise Zero Trust program. Develops Air Force Technical Orders, TSIPs, and I-Plans; manages document versions and deadlines; creates technical diagrams and visualizations; tracks ATO documentation; and collaborates with DoD stakeholders. Requires familiarity with classified documentation, DoD standards, and document management systems.

Provides advanced end-user, service desk, classroom technology, audiovisual, endpoint, and IT asset support for a university. Serves as the primary escalation point for complex technical issues, leads technology deployments and upgrades, manages asset records, coordinates vendors, tests new technologies, develops documentation, and mentors support staff. The role requires regular in-person campus attendance with occasional evening and weekend support.

Provides advanced end-user, service desk, classroom technology, audiovisual, endpoint, and IT asset support across a university. Serves as the escalation point for complex issues, coordinates deployments and hardware refreshes, maintains asset and service records, supports endpoint management platforms, manages vendors, develops technical documentation, and mentors support staff and student employees. Requires regular on-campus attendance with occasional evening or weekend support.

Writes, edits, and maintains DoD policies, technical guides, procedures, and compliance documentation. Develops Air Force technical orders, TSIPs, and I-Plans; manages document versions and revisions; creates technical diagrams and visualizations; tracks ATO documentation; handles classified information; and collaborates with DoD stakeholders to ensure accuracy and regulatory compliance.

Designs, deploys, and maintains Azure Kubernetes Service environments and enterprise GitLab CI/CD automation. Builds Helm charts, Kubernetes manifests, and Infrastructure as Code using Terraform, Bicep, or ARM. Supports containerization, observability, secrets management, security scanning, troubleshooting, and Zero Trust compliance. Collaborates with application teams to improve deployment reliability, scalability, and operational resilience across enterprise ICAM mission systems.

Designs and optimizes Power BI dashboards, semantic models, datasets, DAX measures, and reporting solutions for identity governance and administration analytics. Partners with ETL engineers and stakeholders to validate Parquet data from Azure Synapse and SailPoint sources, establish data-quality checks, monitor refreshes, define KPIs, and document data lineage. Supports compliance reporting, access governance, audit readiness, certification metrics, and Zero Trust analytics.

Designs and develops instructor-led, virtual, online, hybrid, and software training programs. Collaborates with government agencies, subject matter experts, and instructional designers to gather requirements and create engaging learning content, user guides, webinars, and online help systems. Applies the ADDIE process and adult learning theory, ensures Section 508 compliance, and manages training program planning, development, delivery, and evaluation. Requires U.S. citizenship and successful completion of a CBP Tier 4 background investigation.

Provides senior technical solutions advisory services, including architecture assessment, technology research, system design, product recommendations, strategic planning, lifecycle sustainment, pricing, proposals, and market studies. Focuses on Avaya and Unified Communications environments, including E911, recording, licensing, third-party support, and remote-site upgrades. Develops technical plans and presentations, advises stakeholders on cost, schedule, and quality, and may lead teams or mentor less experienced professionals.

Designs and implements ServiceNow IT Asset Management solutions using SAM and HAM modules. Responsibilities include requirements analysis, solution architecture, configuration, integrations, lifecycle and license compliance management, process assessments, stakeholder and vendor collaboration, training, reporting, and continuous improvement. The role serves as an ITAM subject matter expert and requires remote work within the Continental US with up to 10% travel.

Leads the engineering organization responsible for Maritz Rewards, Fulfillment, and Commerce platforms. Defines technology strategy and architecture, guides cloud and commerce technology decisions, promotes responsible AI-assisted development, and mentors managers and architects. Manages executive, client, vendor, security, compliance, budget, and operational relationships while driving scalable, secure solutions across catalog, redemption, order management, payments, and fulfillment integrations.

Lead strategy and operations for high-availability enterprise platforms (HP NonStop, Stratus, mainframe, Linux/x86). Drive modernization, resiliency, capacity planning, incident/problem management, security and compliance, vendor and budget management, and engineering leadership for 24x7 mission-critical infrastructure. Present metrics to executives and coordinate cross-functional initiatives.

Leads an Operations and DevOps team supporting secure, resilient OpenShift environments for an intelligence customer. Responsibilities include team leadership, system administration, troubleshooting, testing, hardening, configuration, deployment automation, CI/CD support, security operations, PKI management, Helm chart development, Infrastructure as Code, documentation, compliance, and performance monitoring. The role requires collaboration with government customers and users, Agile/SAFe experience, cybersecurity implementation, cloud expertise, Kubernetes/OpenShift skills, and an active TS/SCI clearance with CI polygraph eligibility.

Leads teams and strategy for manufacturing processing applications and platforms, including scheduling, inventory, reporting, capacity planning, and operational modeling. Partners with manufacturing and technology stakeholders to deliver reliable, scalable solutions, automation, modernization, and continuous improvement. Oversees application portfolios, production support, incident management, performance metrics, prioritization, and operational planning while developing high-performing teams and improving manufacturing efficiency, throughput, accuracy, and service delivery.