Top Software Engineer Jobs in Houston, TX

Leads the Bioinformatics Software Engineering team and owns engineering strategy, architecture, delivery, modernization, and production support for clinical genomics platforms. Oversees software engineers, bioinformatics workflows, data integration, automation, quality systems, release governance, reliability, and regulatory compliance. Partners with clinical, laboratory, scientific, quality, product, operations, and executive stakeholders to convert research methods into validated production workflows. Guides AI-enabled engineering initiatives while ensuring privacy, traceability, clinical-grade quality, and operational resilience.

The Senior Full Stack Software Engineer will lead software architecture and implementation, mentor team members, and integrate complex systems for minerals supply chain management.

Design, develop, test, and maintain software for enterprise and embedded systems using C/C++, Python, and LabVIEW. Lead projects, mentor junior engineers, troubleshoot complex defects, create technical documentation, support deployments, and ensure compliance with AS9100/ISO processes.

Develop, integrate, test, and maintain mission design simulations and software tools for NASA and commercial spaceflight programs. Implement coding standards, use source control and CI/CD, produce software documentation, support Class C software processes per NPR 7150.2, and collaborate with NASA civil servants and contractors.

Build and maintain scalable financial data infrastructure, including ingestion, validation, normalization, and integrations. Develop systems that calculate portfolio performance metrics efficiently across high-volume datasets, improve reliability and observability, and support distributed processing. Create internal tools, dashboards, reusable schemas, asset data feeds, and self-service analytics capabilities. Collaborate cross-functionally to expand market-data coverage, support B2B integrations, and strengthen operational resilience.

The Staff Software Engineer will shape technical direction, build developer platforms, and design AI agents, enhancing developer productivity and collaboration across teams.

As a Senior Software Engineer, you will design and build a cutting-edge identity search platform and implement AI systems for defense applications, working closely with cross-functional teams to enhance user workflows and support national security.

As a Software Development Engineer in Test, you'll create and conduct automated tests, resolve technical issues, and collaborate with development teams to ensure software quality.

The Staff Software Engineer will lead technical strategy, ensure system availability, and develop backend systems at scale, collaborating across teams to drive capacity modeling and operational quality.

As a Senior Software Engineer, you will design and maintain systems, mentor team members, and improve both code quality and team practices.

Lead frontend development using React and TypeScript to design scalable frontend architecture, components, and developer workflows. Own feature delivery from concept to launch, improve CI/CD and testing, collaborate with backend on APIs, evaluate new technologies, and mentor other engineers while ensuring performance, accessibility, and reliability across web surfaces.

Lead cross-pod technical direction and system design for high-scale backend services, embed AI-native development practices, collaborate with product and design, mentor engineers, and drive ambiguous initiatives from design through production.

Lead architecture and implementation for a secure distributed data platform runtime. Design Go-based concurrency, subprocess supervision, inter-service protocols, distributed persistence, and resilient processing pipelines. Debug complex cross-process and network issues, define testing standards, conduct end-to-end integration and resilience testing, participate in on-call rotations, and lead incident post-mortems. Collaborate with product, engineering, and customer stakeholders to refine requirements and deliver production-ready capabilities. Requires up to 25% international travel to the Middle East.

Build and operate production custody systems: signing service, key management, chain integrations, and transaction pipelines. Own end-to-end subsystems, integrate new chains, collaborate with cryptography on threshold signing and key recovery, write post-mortems, and produce clear async design docs and PRs.

Lead architecture updates and REST API integration for a federal environmental consultation platform. Implement cloud data integration, species display functionality, consultation logic, interoperability fixes, demo environment support, production deployments, and operational documentation. The role requires backend development, federal application integration, accessibility compliance, Git-based development, FedRAMP deployment knowledge, and the ability to obtain Public Trust clearance.

Lead development of decision logic engines and regulatory consultation workflows for a federal Endangered Species Act platform. Implement species routing, agency-specific templates, REST integrations, testing, defect resolution, documentation, and approved updates. Maintain code review and version-control standards while supporting government acceptance and production feedback.

Build and maintain backend computation engines for solar and electrical design. Develop simulation and optimization systems for PV and battery storage layouts, component selection, and electrical configuration. Translate physical models into reliable, scalable software, shape computation infrastructure, write tested code, mentor teammates, collaborate cross-functionally, and own services through production and on-call support.

Designs, codes, tests, documents, and supports complex software applications and integrations. Leads technical work across applications, translates business needs into functional solutions, performs impact analysis, estimates development work, and contributes to architecture and roadmaps. Collaborates with stakeholders, IT teams, vendors, and business units while mentoring developers and supporting project delivery. Requires experience with Angular, .NET, Azure or AWS cloud solutions, relational databases, integration tools, and software development lifecycles.

Modernize and maintain a large-scale React Native mobile app with offline-first architecture, BLE device integrations, data synchronization, and performance improvements. Influence architecture, mentor developers, collaborate across teams, and occasionally visit customer farms to understand workflows.

Build full-stack features and infrastructure analytics products to improve Netflix's cloud and AI efficiency. Design frontends (React/TypeScript), backend services/APIs (GraphQL/Node), shape data models, collaborate with analytics and data engineers, and own product direction from design through implementation.

Modernize and evolve a large-scale React Native mobile app with offline-first architecture, BLE device integrations, local data storage and sync. Improve performance, reliability, and scalability, influence architecture, mentor developers, collaborate cross-functionally, and occasionally visit farms to understand user workflows.

Build and maintain user-facing math tools (2D/3D graphing, geometry, Desmos Notebook). Collaborate on design, code review, testing, deployment, and accessibility. Ship features, pair program, and grow as an early-career engineer.

Designs and maintains Java and Spring Boot microservices for a secure, cloud-native foundation platform. Builds authentication and identity integrations using SAML, OAuth 2.0, OIDC, JWT, and RBAC; develops AWS infrastructure and resilient distributed systems; supports CI/CD, production operations, and on-call response. Provides technical leadership through architecture, code reviews, mentoring, and cross-functional collaboration while maintaining compliance with confidentiality, HIPAA, and regulatory requirements.

Develop and maintain the DrChrono EHR platform across the full software development lifecycle. Responsibilities include requirements gathering and estimation, backend and frontend development, automated testing, deployment, documentation, prototyping, code reviews, mentoring, pair programming, demonstrations, and participation in Agile ceremonies. The role focuses on delivering stable, high-quality software using Python, Django, React, TypeScript, JavaScript, relational databases, and modern engineering practices.

Build and operate highly performant backend systems powering fraud-detection Identification APIs. Design scalable services for real-time processing, own reliability through SLIs, SLOs, observability, on-call response, and incident follow-up, and conduct capacity planning, load testing, and performance tuning. Partner on integrations, automate operational tasks, maintain production services, and mentor engineers in a globally remote environment.