Top Senior IT Jobs in Houston, TX

The IT Systems Engineer III will improve Ophelia's IT systems through integration, automation, and security while managing IT projects, overseeing service providers, and ensuring compliance.

Lead installation, configuration, troubleshooting and delivery of Open iT products. Engineer and manage complex implementation projects, assist Delivery Manager, and mentor other engineers. Ensure automated installs, logging/monitoring, and cross-platform support across Windows and Unix/Linux environments.

Lead development and ownership of core MDR platform components (high-performance log analytics, post-processing, multi-tenant syslog cluster, cross-platform agents). Make architectural decisions, mentor engineers, drive CI/CD/cloud deployments, ensure security, observability, and zero-downtime production operations.

Provide day-to-day IT support for a globally distributed AI company: triage help-desk tickets, provision and ship laptops, manage Google Workspace, enforce endpoint security and device compliance, run onboarding/offboarding, maintain SaaS seat/license management, support office networking/AV, write runbooks, and contribute to security, infrastructure, and automation projects as the first EMEA IT hire.

Lead Data QA for the Enterprise Data Warehouse: define QA strategy, design and execute source-to-target validations, CDC and ETL checks, data masking verification, build quality dashboards and automations, mentor QA analysts, manage defects and release readiness, and collaborate with Data Engineering, BI, Product, and stakeholders to ensure data is accurate, complete, and audit-ready.

Lead design, implementation, and support of enterprise LAN/WAN/WLAN/SD-WAN, cloud, and data center networks. Serve as technical lead for complex infrastructure projects, provide Level 3/4 support, ensure security and compliance (CMMC/NIST/CIS/FIPS), mentor engineers, drive automation and standards, and participate in incident response and audits.

Senior IT leader partnering with Commercial leadership to define and deliver pharma commercial technology strategy, oversee Veeva and digital platforms, lead product launch technology readiness, manage vendors/agencies, ensure compliance and governance, and lead IT teams to deliver scalable, secure commercial applications and digital experiences.

Lead Veeva CRM implementations for life sciences clients: gather requirements, design processes, support solution design across Veeva modules, manage UAT and data migration, coordinate with architects and PMs, and provide post-go-live support and continuous improvement.

The Lead IT Telecom Architect designs and optimizes Telecom and Contact Center architecture to meet business goals, ensuring security and performance. Responsibilities include strategy development, technology evaluation, system implementation oversight, and stakeholder collaboration.

Consult as a Director-level technologist for alternative asset firms and family offices: assess tech practices, advise CTOs, lead application and infrastructure projects, oversee cybersecurity, disaster recovery, vendor selection, KPIs, and team governance to align technology roadmaps with business needs.

Perform IT and integrated audits, document and test controls, support SOX and compliance activities, assist external auditors, conduct walkthroughs and data analytics, write reports and recommend remediation, and provide training and project management support.

Lead enterprise IT sourcing and software procurement for complex renewals and strategic sourcing initiatives. Drive savings, establish governance, create vendor strategies and KPIs, partner with IT and stakeholders, mentor procurement staff, and manage contract negotiations and renewals.

Design, modify, and program software for local, networked, cloud, or internet applications. Write code, test and debug, document installation and maintenance procedures, gather user requirements, implement enhancements, and perform related duties.

Lead and mentor the Infrastructure team and deliver the enterprise infrastructure roadmap. Design and maintain resilient on-prem and cloud (Azure) network and server environments, oversee capacity planning, monitoring, backup/recovery, disaster recovery, vendor management, and infrastructure automation. Support ERP/Sage X3 infrastructure, collaborate with InfoSec on vulnerability remediation and OT teams for manufacturing environments, and manage infrastructure projects and on-call escalations.

Lead on-site migrations and go-lives for Oracle OPERA Cloud at hotel properties across India. Clean and migrate OPERA data, manage cutovers, and train front desk and management teams. Serve as subject-matter expert bridging hotel operations and OPERA technical deployment.

Remote IT Manager responsible for analyzing, upgrading, and administering IT systems (networks, servers, email, backups), evaluating vendors and technologies, managing projects, tracking inventory, training staff, and providing technical support to improve operational efficiency.

Lead mobile deployment teams for data center operations. Responsibilities include on-site leadership, operational control, client interface, and team management, while ensuring efficiency and quality during deployments under high-pressure conditions.

Lead network architecture and delivery for MSP engagements across LAN/WAN, SD-WAN, wireless, and network security. Provide pre-sales design, hands-on implementation of Extreme and Fortinet platforms, develop standards and templates, perform network assessments, mentor junior engineers, and represent the practice in client-facing strategy discussions.

Lead IT Manager for Data Operations and Platforms, responsible for strategy, development, and management of data products and analytics platforms, overseeing team performance and ensuring compliance with security standards.

Senior-level Workday systems analyst responsible for enterprise administration, configuration, security, integrations, release management, reporting, and data integrity across HCM, Payroll, Finance, and Student modules. Serves as IT bridge to functional teams, leads change control, incident response, audits, and optimization efforts while maintaining compliance with FERPA/Title IV and IT security best practices.

Lead and operate a 24x7 IT and OT Security Operations Center as a player/coach. Manage SOC staff and MDR relationships, oversee detection, investigation, and response across IT and industrial control systems, drive AI/ML and automation adoption, maintain playbooks and metrics, and collaborate with cross‑functional teams to improve security posture.

Serve as a senior strategic technology advisor between Managed Business and IT, develop multi-year roadmaps, prioritize investments, lead AI/automation/analytics and digital transformation initiatives, manage governance and value realization, and drive customer experience and operational scalability.

Lead and develop an IT team to run secure, scalable infrastructure and support services. Oversee daily operations, project delivery, vendor management, compliance with security/regulatory frameworks, performance metrics, budgeting, and continuous improvement while partnering with business leaders.

Lead and mentor Scrum teams and Scrum Masters across high-complexity IT initiatives. Facilitate Agile ceremonies, remove impediments, drive continuous improvement, provide metrics to leadership, protect teams from distractions, and oversee delivery for cloud and AI-enabled enterprise transformations.

Lead client-facing Salesforce Marketing Cloud engagements for life sciences clients: run discovery and journey mapping, capture requirements, design omnichannel solutions, translate to implementation-ready user stories, coordinate delivery with architects, developers, QA and agencies, and support launch, validation, and post-launch optimization while ensuring regulated documentation and consent controls.