Top Senior Level Jobs in St. Louis, MO

Reposted 11 Days AgoSaved
Remote or Hybrid
St. Louis, MO
85K-120K Annually
Senior level
85K-120K Annually
Senior level
Cloud • Computer Vision • Information Technology • Sales • Security • Cybersecurity
Analyze in-the-wild exploits and perform deep reverse engineering to track adversaries. Build detection, automation, and classification frameworks; develop host/network signatures and tooling. Produce high-quality intelligence reports and briefings, collaborate across teams, and contribute to mitigation and large-scale hunting efforts.
Top Skills: Ai-Assisted ToolsDebuggersDecompilersDisassemblersDynamic Analysis FrameworksLinuxLlmsWindowsPythonSnortStatic Analysis FrameworksYara
14 Days AgoSaved
Hybrid
St. Louis, MO
83K-157K Annually
Senior level
83K-157K Annually
Senior level
Artificial Intelligence • Fintech • Insurance • Marketing Tech • Software • Analytics
Provides consultative loss prevention and safety services to commercial customers, including on-site evaluations, risk assessments, data analysis, service planning, and implementation. Advises clients and internal consultants on regulations, technology, industry trends, and risk reduction methods. Mentors less experienced consultants, supports business development and customer retention, develops service tools and policies, and builds industry relationships. Regular travel is required.
Top Skills: MS Office
15 Days AgoSaved
In-Office
St. Louis, MO
165K-215K Annually
Senior level
165K-215K Annually
Senior level
Aerospace • Artificial Intelligence • Computer Vision • Software • Analytics • Defense • Big Data Analytics
Operate and improve multi-site Red Hat OpenShift and Kubernetes platforms across on-premise and hybrid cloud environments. Responsibilities include cluster lifecycle management, CI/CD, infrastructure as code, monitoring, incident response, security hardening, automation, self-service tooling, and recovery capabilities. The role supports mission-critical workloads in secure or disconnected environments and collaborates with storage, network, security, development, and operations teams.
Top Skills: AnsibleArgo CdAstra TridentAWSAzureBashCi/CdCsiGCPGithub ActionsGitlab CiGitopsGoIscsiJenkinsKubernetesLinuxNetapp OntapNfsPythonRed Hat OpenshiftSafe AgileTerraform
18 Days AgoSaved
Hybrid
St. Louis, MO
250K-290K Annually
Senior level
250K-290K Annually
Senior level
eCommerce • Mobile • Payments
Leads executive-level client partnerships, strategic account planning, complex multi-product negotiations, revenue expansion, and consultative sales initiatives. Delivers data-driven presentations and QBRs, identifies growth opportunities, collaborates cross-functionally, mentors revenue teams, and drives strategic client outcomes. Requires travel exceeding 40% and supports major advertising, retail, and consumer packaged goods accounts.
Top Skills: Google SuiteLookerSalesforce
27 Days AgoSaved
Hybrid
St. Louis, MO
67K-336K Annually
Senior level
67K-336K Annually
Senior level
Cloud • Information Technology • Security • Software • Cybersecurity
Leads customer-facing technical discovery, architecture, demonstrations, evaluations, proofs of value, and technical close for Cloudflare One solutions. Advises enterprise customers on Zero Trust, SASE, secure connectivity, WAN transformation, AI security, and related technologies. Partners with sales, product, engineering, support, and customers to drive successful evaluations, communicate business value, create reusable technical assets, and provide feedback for product improvement.
Top Skills: Agentic AiAi SecurityAPIsBgpBrowser IsolationCasbCloud NetworkingCloudflare AccessCloudflare GatewayCloudflare OneCloudflare One ClientCloudflare TunnelDkimDlpDmarcEmail SecurityEnterprise WanGenerative AiGoogle WorkspaceGreIdentity ProvidersIpsecLog AnalyticsMcpMicrosoft 365MplsNetwork FirewallsRoutingSaseScriptingSd-WanSIEMSmtpSpfSseSubnettingVpnZero Trust
YesterdaySaved
In-Office
St. Louis, MO
113K-338K Annually
Senior level
113K-338K Annually
Senior level
Information Technology
Designs, builds, and scales enterprise AI applications using classical machine learning, generative AI, RAG, and agentic architectures. Develops intelligent workflows, autonomous agents, knowledge systems, chatbots, copilots, and decision-support solutions integrated with enterprise platforms and APIs. Leads AI governance, evaluation, observability, security, and human-in-the-loop controls while advising clients on enterprise AI transformation. Requires extensive experience with Claude, OpenAI, LLMs, cloud platforms, vector databases, semantic search, and production-grade AI implementations.
Top Skills: Agentic AiAnthropic ClaudeAPIsAWSAzureCloud-Native ArchitecturesData Engineering PipelinesEmbedding ModelsGenerative AiGCPKnowledge GraphsLarge Language ModelsMachine LearningOpenai GptPythonRetrieval-Augmented GenerationSemantic SearchSQLVector Databases
YesterdaySaved
In-Office
St. Louis, MO
87K-294K Annually
Senior level
87K-294K Annually
Senior level
Information Technology
Designs enterprise data fabric solutions across on-premises and multi-cloud environments. Integrates data virtualization, metadata, knowledge graphs, cataloging, and automated integration into connected data layers supporting analytics and AI. Defines scalable reference architectures, governance patterns, data products, self-service consumption, and real-time delivery. Advises client architects and leaders on data modernization initiatives using cloud platforms, data mesh, APIs, and streaming architectures.
Top Skills: Active MetadataAPIsAutomated Data IntegrationAzure SynapseBigQueryCloud Data PlatformsData CatalogingData MeshData ProductsData VirtualizationDatabricksEltETLKnowledge GraphsMetadata And Lineage ToolingSnowflakeStreaming Architectures
YesterdaySaved
In-Office
St. Louis, MO
87K-294K Annually
Senior level
87K-294K Annually
Senior level
Information Technology
Leads enterprise data engineering, data fabric architecture, governance, and AI platform delivery. Designs cloud data platforms, ETL/ELT pipelines, ontologies, APIs, streaming architectures, metadata lineage, and data quality controls. Integrates Salesforce, Palantir Foundry, and AI/ML workflows while enabling KPI measurement and business value realization. Advises clients, defines reference architectures, maintains platform integrity, and drives reusable data assets and modernization solutions.
Top Skills: AlationApache KafkaSparkAws GlueAws KinesisAzure Data FactoryAzure Event HubsAzure Synapse AnalyticsCollibraDatabricksDbtGoogle BigqueryGraphQLInformaticaPalantir FoundryPythonRag PipelinesRest ApisSalesforceSnowflakeSnowparkSQLVector Databases
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Reposted YesterdaySaved
In-Office or Remote
St. Louis, MO
65K-75K Annually
Senior level
65K-75K Annually
Senior level
Consulting
Leads end-to-end quality management across BPO and contact center programs, including monitoring frameworks, scorecards, calibration, data analysis, root cause analysis, corrective actions, compliance, and continuous improvement. Partners with operations, training, WFM, IT, and clients to improve customer experience and performance. Oversees launches, transitions, and stabilization efforts; presents results to clients; manages escalations; and leads, coaches, and develops quality teams.
Top Skills: Automated Quality AssuranceDmaicGdprHipaaIso 9001KaizenLean Six SigmaExcelPci-DssPower BIQa PlatformsSpeech AnalyticsTableauText Analytics
YesterdaySaved
In-Office or Remote
St. Louis, MO
180K-210K Annually
Senior level
180K-210K Annually
Senior level
Consulting
Owns the full new-logo enterprise sales cycle for BPO, customer experience, and technology-enabled transformation services. The role requires independently creating pipeline, engaging C-suite executives, developing business cases, coordinating internal pursuit teams, negotiating commercial models, and closing complex deals. The successful candidate will leverage executive relationships, industry networks, AI and transformation expertise, and strong commercial judgment to achieve revenue targets. This is a highly visible, self-directed individual contributor role requiring extensive travel.
Top Skills: AIAnalyticsAutomationCrm PlatformsDigital Transformation Technologies
YesterdaySaved
In-Office or Remote
St. Louis, MO
47K-122K Annually
Senior level
47K-122K Annually
Senior level
Fitness • Healthtech • Retail • Pharmaceutical
Supports Aetna Better Health of Virginia’s finance team through financial reporting, regulatory reporting, data analysis, premium reconciliation, and trend identification. Uses SQL, SQL Server Management Studio, Excel, and visualization tools to manage data, produce insights, streamline processes, and support strategic decisions. Partners with internal and external stakeholders, communicates business and technical requirements, contributes to projects as a subject matter expert, and identifies cost and efficiency opportunities.
Top Skills: Generative AiExcelPower BISQLSql Server Management StudioTableau
YesterdaySaved
In-Office
St. Louis, MO
107K-213K Annually
Senior level
107K-213K Annually
Senior level
Fitness • Healthtech • Retail • Pharmaceutical
Leads Scrum teams and complex technology initiatives through Agile coaching, ceremony facilitation, impediment removal, stakeholder communication, metrics analysis, and continuous improvement. The role supports enterprise-wide delivery, optimizes Agile SDLC processes, coaches leaders and teams, and uses project management skills for planning, coordination, resource forecasting, and execution.
Top Skills: AgileCa RallyConfluenceMicrosoft TeamsScrumSdlcSharepoint
Reposted YesterdaySaved
In-Office or Remote
St. Louis, MO
68K-199K Annually
Senior level
68K-199K Annually
Senior level
Fitness • Healthtech • Retail • Pharmaceutical
Leads Health100’s B2B partner marketing strategy across healthcare audiences, including demand generation, pipeline growth, sales enablement, partner messaging, launches, and commercial readiness. Develops audience-specific value propositions and marketing materials, collaborates with Sales and Product teams, gathers commercial insights, and establishes KPIs to measure partner engagement and marketing impact. The role may be hybrid in Massachusetts, Rhode Island, or New York, with full-time remote consideration.
Top Skills: Health100
YesterdaySaved
In-Office
St. Louis, MO
72K-85K Annually
Senior level
72K-85K Annually
Senior level
Real Estate
Manages complex corporate real estate transactions and property portfolios, including leases, sales, subleases, purchases, negotiations, budgeting, financial reporting, compliance, and client communications. Develops strategic occupancy plans, identifies cost-saving opportunities, oversees transaction teams and brokers, coordinates legal reviews and documentation, facilitates client meetings, and implements standardized processes, performance metrics, and account playbooks. Requires strong real estate transaction management, financial analysis, negotiation, leadership, and strategic planning skills.
YesterdaySaved
In-Office
St. Louis, MO
136K-160K Annually
Senior level
136K-160K Annually
Senior level
Real Estate
Drives transformation initiatives across Investor Services by defining strategic roadmaps, identifying optimization opportunities, redesigning processes, and implementing automation, AI, and shared-services solutions. Leads cross-functional projects, manages and develops analysts, evaluates business value, advises leadership, analyzes organizational issues, and communicates recommendations through data-driven presentations. Ensures projects are delivered effectively, on time, and within budget while influencing stakeholders across the organization.
Top Skills: AIAutomation
YesterdaySaved
In-Office
St. Louis, MO
106K-125K Annually
Senior level
106K-125K Annually
Senior level
Real Estate
Manages commercial real estate transactions for national and global clients, including leases, sales, subleases, and purchases. Oversees negotiations, documentation, financial analysis, reporting, workflow governance, broker coordination, legal review, client meetings, site visits, and strategic portfolio planning. Maintains client relationships, ensures regulatory and process compliance, identifies occupancy cost opportunities, improves transaction processes, and may supervise supporting team members.
YesterdaySaved
In-Office or Remote
St. Louis, MO
79K-127K Annually
Senior level
79K-127K Annually
Senior level
Healthtech
Manage tax compliance, tax accounting, GAAP and statutory tax provisions, tax forecasts, research, planning, government examinations, and financial statement disclosures for Highmark Health and its subsidiaries. Prepare filings, calculations, workpapers, and supporting documentation; monitor tax-law changes; advise management on tax issues and opportunities; coordinate with auditors, government authorities, subsidiaries, and tax staff.
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