Top Machine Learning Jobs in St. Louis, MO

DoD SkillBridge Fellows gain practical experience through assigned projects, collaboration with experienced professionals, and exposure to operational processes, technologies, and mission objectives. Opportunities span telecommunications, acquisition and procurement, technology, accounting, finance, and other areas. Participants are compensated by their military employer during the fellowship and may be considered for full-time employment afterward based on performance and organizational needs.

Own the technical side of deal progression for airline deployments: qualify opportunities, run demos and POCs, author integration and deployment architectures (PSS, APIs, data feeds, DNS, identity, networking), respond to RFPs/security questionnaires, scope SOWs and NFRs, and build reusable demo/reference assets to drive adoption and expansion while liaising between sales, engineering, and customers.

Lead data science projects from ideation through enterprise impact, building scalable and well-tested solutions that improve healthcare outcomes. Apply probability, statistics, machine learning, SQL, and Python to develop data-driven products and insights. Partner with stakeholders, assess product performance, identify strategic improvements, mitigate risks, and mentor teammates while aligning initiatives with business objectives.

Own and build Nectar Social’s React Native mobile platform for iOS and Android. Responsibilities include establishing architecture, shared components, testing, CI/CD, performance standards, monitoring, and error tracking. The engineer will develop AI-powered experiences, integrate social and e-commerce APIs, support real-time data-intensive features, and collaborate with product, design, and company leadership to shape the product and technical direction.

Own end-to-end strategy, roadmap, delivery, adoption, safety, and commercial readiness for AI-native cybersecurity products. Conduct customer and partner discovery, lead 0-to-1 launches, define experimentation and evaluation frameworks, and collaborate with engineering, design, sales, finance, and executives. The role requires hands-on LLM product expertise, strong judgment in ambiguous environments, and a focus on trusted AI experiences for security professionals and MSP/MSSP partners.

Build and deploy AI-driven process optimization models for refineries and petrochemical plants. Scope customer opportunities, analyze plant time-series data, develop and validate process models, commission closed-loop optimizers, train operators, troubleshoot deployed models, and support plant-system integrations. The role also leads technical customer relationships, manages implementation projects, documents workflows, and channels field feedback to product and R&D teams.

Develop and deploy AI solutions from problem framing through production. Responsibilities include identifying AI opportunities, leading MVP development, building data pipelines, experimenting with generative LLMs, fine-tuning NLP models, and delivering scalable features. The intern will collaborate cross-functionally, communicate technical impact to business audiences, and work with cloud platforms such as AWS or Google Cloud.

Support partner sales opportunities through discovery calls, product demonstrations, technical responses, solution scoping, project planning, proof-of-concept coordination, RFI/RFP responses, and security questionnaires. Collaborate with sales, professional services, product, engineering, and delivery teams while building partner relationships and developing expertise in fraud prevention and financial crime solutions.

Lead end-to-end product design for an AI-powered women’s health platform. Responsibilities include defining UX vision, creating interaction models, information architecture, wireframes, high-fidelity interfaces, prototypes, design systems, and user research. Collaborate with product, engineering, ML, marketing, and leadership teams to translate business needs into customer-focused solutions, manage design initiatives, and measure product success through user feedback and metrics.

Lead Nabla’s marketing organization and product marketing strategy across healthcare segments, buyer types, and direct and partner channels. Own positioning, messaging, launches, competitive intelligence, sales enablement, demand strategy, content prioritization, marketing operations, pipeline attribution, and team development. Manage a 6–8-person team spanning product marketing, growth content, design, and marketing operations while guiding resourcing and hiring decisions.

Leads the transformation of Sophos’s pricing operations by building a centralized function, establishing pricing governance and review cadences, developing AI-assisted competitive and discount analysis capabilities, and aligning pricing across SecOps and Network Security. The role provides executive market visibility, defines performance metrics, supports organizational change, and builds a high-performing team serving sales, finance, and customer-facing stakeholders.

The Tarbell Fellowship combines three months of remote training in AI and journalism fundamentals with a nine-month newsroom placement as an artificial intelligence reporter. Fellows write and investigate AI-related topics, build journalism skills, complete coursework and assignments, and attend a weeklong in-person summit. The program is full-time and intended for candidates with journalism or AI expertise, strong writing ability, persistence, curiosity, and open-mindedness. Senior fellowships are available to candidates with at least seven years of experience and exceptional prior work.

Own the strategy, roadmap, and investment priorities for foundational agricultural data products, including pipelines, data models, APIs, and shared services. Partner with engineering, architecture, data science, and product teams to deliver scalable, governed, high-quality data capabilities. Prioritize initiatives based on customer and commercial value, define success metrics, resolve cross-team tradeoffs, and expand data support for analytics, predictive modeling, machine learning, and AI applications.

Lead end-to-end LLM inference performance across serving systems, models, GPU hardware, and workloads. Define rigorous benchmarks, diagnose bottlenecks from scheduling through kernels and interconnects, optimize single- and multi-node deployments, and deliver production-ready runtimes and configurations. Collaborate with product and infrastructure teams, evaluate inference technologies, and implement runtime fixes. The role requires strong Python engineering, production experience with serving engines such as vLLM or SGLang, GPU profiling, and knowledge of modern inference optimization techniques.

Build and deploy production machine learning systems that optimize Samsara’s global hardware supply chain. Responsibilities include demand, inventory, lead-time, spend, and supplier-risk forecasting; anomaly detection; feature engineering and ETL; real-time inference; MLOps; data infrastructure improvements; governance; and model monitoring. The role defines the AI transformation roadmap, partners with executive and cross-functional stakeholders, mentors scientists, and drives adoption of AI-enabled operational workflows.

Lead client engagements from data onboarding through production, plan studies that demonstrate business value, and build automated machine learning workflows using Python, scikit-learn, pandas, and Spark. Translate client business questions into data solutions, manage stakeholder relationships, evaluate model performance, and inform product planning. Requires healthcare or life sciences data experience and end-to-end delivery of sophisticated data or machine learning solutions.

Lead UX design initiatives across a healthcare product suite, solving complex user and business problems through research, prototyping, interaction and visual design. Mentor designers, influence cross-functional teams, contribute to the design system, and establish scalable design standards. Collaborate with engineering, product, leadership, and data science teams to integrate ML features and deliver intuitive, consumer-quality healthcare experiences.

Lead UX design initiatives across a healthcare product suite, solving complex problems through prototyping, user research, and strategic design. Collaborate with engineering, product, leadership, and data science teams to create consumer-quality experiences, integrate ML features, and evolve scalable design systems. Mentor designers, resolve stakeholder feedback, establish design standards, and drive innovation across large-scale projects.

Lead atmospheric research for a rainfall enhancement startup, directing meteorological science, WRF modeling, data assimilation, deployment evaluation, and operational forecasting. Integrate radar, satellite, sounding, surface, and field-sensor data; develop cloud and HPC modeling workflows; assess AI weather models; and communicate uncertainty. Recruit and lead scientific and engineering teams while building partnerships with universities and research institutions. Frequent travel is required.

Leads a clinical support team delivering patient engagement and medication adherence programs. Responsibilities include developing intervention strategies, managing productivity and timelines, ensuring quality standards, representing clinical care in customer meetings, hiring and training staff, conducting performance reviews, addressing patient and provider questions, and complying with healthcare regulations.

Leads Yahoo’s centralized CRM organization and owns the performance, strategy, governance, operations, innovation, and roadmap for email, push, SMS, newsletters, and other messaging channels. Oversees engagement, retention, revenue, deliverability, personalization, experimentation, quality, compliance, budgets, vendors, and cross-functional partnerships with Product, Engineering, Analytics, Legal, and Marketing. Develops senior leaders and scales AI-enabled CRM capabilities across Yahoo’s global consumer products.

Design, build, evaluate, and productionize machine learning and LLM-based agentic systems for healthcare products. Own projects end-to-end, including problem framing, dataset development, modeling, evaluation, deployment, monitoring, and safety guardrails. Build ML infrastructure, data pipelines, inference systems, and evaluation frameworks. Collaborate with clinicians, product managers, and engineers, while setting technical direction and mentoring team members.

Lead the engineering organization for BlueCat’s Network Observability product line. Own technical strategy, architecture, roadmap, delivery, and operational excellence for data-intensive network monitoring platforms spanning SaaS and on-premise deployments. Build AI-driven observability capabilities, modernize legacy systems, establish engineering standards, and develop distributed teams. Partner with product, executive leadership, customers, sales, and support to achieve business goals and resolve strategic technical issues.

Paid 9-week hybrid internship supporting data and business technology initiatives at the Federal Reserve Bank of St. Louis. Projects may involve Python and AWS database analysis, product ownership, security compliance, statistical analysis, policy research, data science, machine learning, and GenAI experimentation. Interns participate in networking, mentoring, professional development, and mission-driven projects.

Lead a team of bookkeeping professionals, manage client engagements and deadlines, build scalable bookkeeping processes, support client interactions, collaborate with engineering and product teams on accounting automation, and coordinate transitions to tax services. The role requires substantial client accounting services experience, team-building and process-development expertise, and close collaboration with tax advisors. CPA certification and startup experience are preferred.