Top Machine Learning Jobs in St. Louis, MO

Leads enterprise FinOps AI and cloud engineering initiatives, defining agentic AI architectures, MCP integrations, policy-as-code, IaC guardrails, automation pipelines, security controls, telemetry, and executive dashboards. Manages multi-workstream, multi-cloud delivery squads, scales reusable FinOps components, supports client consulting and sales pursuits, and ensures compliance with enterprise AI standards. The role requires extensive cloud, FinOps automation, program leadership, and agentic AI experience.

Own the strategy, roadmap, and investment priorities for foundational agricultural data products, including pipelines, data models, APIs, and shared services. Partner with engineering, architecture, data science, and product teams to deliver scalable, governed, high-quality data capabilities. Prioritize initiatives based on customer and commercial value, define success metrics, resolve cross-team tradeoffs, and expand data support for analytics, predictive modeling, machine learning, and AI applications.

Lead end-to-end LLM inference performance across serving systems, models, GPU hardware, and workloads. Define rigorous benchmarks, diagnose bottlenecks from scheduling through kernels and interconnects, optimize single- and multi-node deployments, and deliver production-ready runtimes and configurations. Collaborate with product and infrastructure teams, evaluate inference technologies, and implement runtime fixes. The role requires strong Python engineering, production experience with serving engines such as vLLM or SGLang, GPU profiling, and knowledge of modern inference optimization techniques.

Build and deploy production machine learning systems that optimize Samsara’s global hardware supply chain. Responsibilities include demand, inventory, lead-time, spend, and supplier-risk forecasting; anomaly detection; feature engineering and ETL; real-time inference; MLOps; data infrastructure improvements; governance; and model monitoring. The role defines the AI transformation roadmap, partners with executive and cross-functional stakeholders, mentors scientists, and drives adoption of AI-enabled operational workflows.

Lead client engagements from data onboarding through production, plan studies that demonstrate business value, and build automated machine learning workflows using Python, scikit-learn, pandas, and Spark. Translate client business questions into data solutions, manage stakeholder relationships, evaluate model performance, and inform product planning. Requires healthcare or life sciences data experience and end-to-end delivery of sophisticated data or machine learning solutions.

Lead UX design initiatives across a healthcare product suite, solving complex user and business problems through research, prototyping, interaction and visual design. Mentor designers, influence cross-functional teams, contribute to the design system, and establish scalable design standards. Collaborate with engineering, product, leadership, and data science teams to integrate ML features and deliver intuitive, consumer-quality healthcare experiences.

Lead UX design initiatives across a healthcare product suite, solving complex problems through prototyping, user research, and strategic design. Collaborate with engineering, product, leadership, and data science teams to create consumer-quality experiences, integrate ML features, and evolve scalable design systems. Mentor designers, resolve stakeholder feedback, establish design standards, and drive innovation across large-scale projects.

Leads a clinical support team delivering patient engagement and medication adherence programs. Responsibilities include developing intervention strategies, managing productivity and timelines, ensuring quality standards, representing clinical care in customer meetings, hiring and training staff, conducting performance reviews, addressing patient and provider questions, and complying with healthcare regulations.

Leads Yahoo’s centralized CRM organization and owns the performance, strategy, governance, operations, innovation, and roadmap for email, push, SMS, newsletters, and other messaging channels. Oversees engagement, retention, revenue, deliverability, personalization, experimentation, quality, compliance, budgets, vendors, and cross-functional partnerships with Product, Engineering, Analytics, Legal, and Marketing. Develops senior leaders and scales AI-enabled CRM capabilities across Yahoo’s global consumer products.

Design, build, evaluate, and productionize machine learning and LLM-based agentic systems for healthcare products. Own projects end-to-end, including problem framing, dataset development, modeling, evaluation, deployment, monitoring, and safety guardrails. Build ML infrastructure, data pipelines, inference systems, and evaluation frameworks. Collaborate with clinicians, product managers, and engineers, while setting technical direction and mentoring team members.

Lead the engineering organization for BlueCat’s Network Observability product line. Own technical strategy, architecture, roadmap, delivery, and operational excellence for data-intensive network monitoring platforms spanning SaaS and on-premise deployments. Build AI-driven observability capabilities, modernize legacy systems, establish engineering standards, and develop distributed teams. Partner with product, executive leadership, customers, sales, and support to achieve business goals and resolve strategic technical issues.

Paid 9-week hybrid internship supporting data and business technology initiatives at the Federal Reserve Bank of St. Louis. Projects may involve Python and AWS database analysis, product ownership, security compliance, statistical analysis, policy research, data science, machine learning, and GenAI experimentation. Interns participate in networking, mentoring, professional development, and mission-driven projects.

Lead a team of bookkeeping professionals, manage client engagements and deadlines, build scalable bookkeeping processes, support client interactions, collaborate with engineering and product teams on accounting automation, and coordinate transitions to tax services. The role requires substantial client accounting services experience, team-building and process-development expertise, and close collaboration with tax advisors. CPA certification and startup experience are preferred.

Applied Data Scientist focused on incrementality, causal inference, experimentation, Marketing Mix Modeling, and predictive products. The role partners directly with customers to interpret data, diagnose measurement issues, explain statistical results, and provide actionable recommendations. Responsibilities include building diagnostic tools, analyzing model and experiment outcomes, improving methodologies and production capabilities, and collaborating with Product, Engineering, Media Strategy, Customer Success, and senior data scientists.

Designs and implements enterprise cloud and AI solutions for unstructured data workloads. Responsibilities include building ingestion pipelines, API integrations, document extraction and HITL workflows, tuning machine learning models, benchmarking performance, and ensuring security, availability, disaster recovery, and data isolation. The role also supports customer developers, leads technical proofs of concept, mentors engineering teams, develops reusable blueprints, and provides feedback to product engineering.

Owns end-to-end delivery of enterprise fine-tuning engagements, including client discovery, use-case prioritization, ROI, scope, timelines, model hosting, SLAs, security reviews, and stakeholder management. Partners with sales, product, engineering, and machine learning teams; navigates enterprise procurement and IT processes; translates between technical buyers and internal teams; and develops repeatable processes and playbooks to scale the practice.

Own and improve Headway’s privacy program across HIPAA, 42 CFR Part 2, state privacy laws, individual rights, incidents, vendor governance, and AI use. Maintain controls, data maps, metrics, training, and operational workflows. Conduct product, vendor, and AI privacy assessments; manage rights requests and incident investigations; coordinate notifications and regulatory submissions; and translate complex requirements into practical guidance for cross-functional teams.

Lead Risk Operations transformation programs from problem definition through implementation and measurement. Own automation initiatives, process redesign, tooling improvements, partner transitions, operational metrics, readiness, and continuous improvement. Collaborate with Risk Operations, Fraud Strategy, Compliance, Product, Engineering, Data, Shared Services, and Vendor Management to deliver measurable gains in service levels, quality, risk outcomes, backlog, and cost.

Own the strategy and roadmap for patient-provider search, retrieval, ranking, and marketplace matching. Lead experimentation, objective functions, evaluation, and ML platform foundations while partnering with ML engineers, data scientists, design, clinical teams, and executives. Improve successful, lasting care matches rather than optimizing only clicks or bookings. Balance patient access, provider growth, clinical quality, and payer priorities, while setting the standard for technically grounded product management.

Own the strategy and roadmap for Netflix’s scaled content ingestion, publishing, and distribution systems. Build automated, API-driven platforms that reduce manual workflows, support partner onboarding, enable reliable content fulfillment, and accelerate global time-to-launch. Partner with engineering, operations, design, data science, and business teams to translate complex operational needs into durable product capabilities and prioritize investments across high-scale media workflows.

Analyze product, user, transactional, and repayment data to develop risk and underwriting models, reduce losses and fraud, monitor model performance, and guide product and growth strategy. Build Looker dashboards and LookML models, conduct segmentation and experimentation, measure CAC and LTV, and communicate actionable insights to product, engineering, marketing, finance, and leadership.

Leads Imprint’s fraud prevention strategy across new account, first-party, and transaction fraud. Owns fraud loss outcomes, controls, team performance, and strategic priorities. Manages three fraud leads, partners with modeling and engineering teams, communicates risk and performance to executives, and serves as an operational backstop during severe fraud incidents. Requires deep money-movement fraud expertise, technical fluency in SQL, SAS, or Python, and experience leading fraud teams with loss or P&L accountability.

Build and scale accounting software synchronization solutions connecting BILL’s payment network with third-party accounting platforms. Lead end-to-end software design and delivery, develop scalable AWS microservices, improve platform performance, guide testing and CI/CD practices, resolve customer problems, mentor engineers, and use generative AI to accelerate development.

Drives underwriting innovation by designing, testing, and implementing new tools, technologies, strategies, and processes. Coordinates projects, manages deadlines and risks, supports user acceptance testing, and collaborates with IT, underwriting, data, product, operations, reinsurance, and vendors. Uses data analytics and machine learning to improve risk assessment, efficiency, and customer experience while ensuring regulatory compliance. Provides training and helps translate innovation concepts into adopted underwriting capabilities.

Lead development and productionization of telematics pricing and underwriting models. Responsibilities span statistical modeling, feature engineering, dataset and pipeline development, model deployment, monitoring, data quality validation, troubleshooting, regulatory support, and collaboration with pricing, actuarial, product, engineering, and compliance teams.