Top Data Science Jobs in St. Louis, MO

Reposted One Month AgoSaved
Remote
St. Louis, MO
Mid level
Mid level
AdTech • Marketing Tech
Design, build, and deploy production-grade machine learning models and analytical solutions. Work end-to-end from problem definition to production, write performant Python and SQL, resolve data quality issues, collaborate with product and engineering, support on-call, automate reporting, mentor junior teammates, and improve model reliability and workflows.
Top Skills: PythonSQL
One Month AgoSaved
Remote
St. Louis, MO
142K-196K Annually
Mid level
142K-196K Annually
Mid level
Healthtech
Develop autonomous AI agents capable of goal setting, decomposition, planning, tool use, memory, and long-horizon execution. Build evaluation frameworks for alignment, reliability, and safety; identify goal misalignment and undesirable behaviors; and integrate agent systems with APIs, databases, search engines, and other tools. Responsibilities include designing production-ready machine learning systems, collaborating across teams, and advancing agent autonomy through planning, causal reasoning, model-based reinforcement learning, and language modeling.
Top Skills: APIsAutogenCausal ReasoningDatabasesETLJaxLangchainLanggraphMcp ServersModel-Based Reinforcement LearningPythonPyTorchSearch EnginesSQLSymbolic PlanningTransformers
One Month AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Cybersecurity
Owns the end-to-end development of cybersecurity vulnerability and exploit prediction models, including problem framing, feature engineering, training, evaluation, deployment, calibration, monitoring, and drift detection. The role addresses extreme class imbalance, hierarchical modeling, cold-start customers, and uncertainty quantification. It also requires explaining model outputs to security executives, publishing methodologies and benchmarks, and partnering with engineering to deploy reliable production systems.
Top Skills: PythonSQL
Reposted One Month AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
AdTech • Big Data • Consumer Web • Digital Media • Marketing Tech
Own end-to-end data science for a priority vertical (starting with Insurance): frame business problems, build and validate models, partner with ML engineering for deployment, monitor live ROAS performance, and drive measurable revenue and lead quality improvements.
Top Skills: AWSCollaborative FilteringDeep LearningEmbeddingsGoogle AdsLlmsLookerLtv ModelingMeta AdsMulti-Armed BanditPythonRanking AlgorithmsRecommendation SystemsReinforcement LearningSQL
Reposted One Month AgoSaved
Remote
St. Louis, MO
183K-183K Annually
Senior level
183K-183K Annually
Senior level
Big Data • Machine Learning • Social Impact • Software
Lead end-to-end data science projects including predictive modeling, algorithm design, and data pipelines. Build campaign-focused models (turnout, partisanship), perform exploration and visualization, translate insights into memos/presentations, collaborate with engineering to productionize models, mentor junior data scientists, and prototype emerging AI solutions for product impact.
Top Skills: GitPythonSQL
Reposted One Month AgoSaved
Remote
St. Louis, MO
185K-400K Annually
Senior level
185K-400K Annually
Senior level
Information Technology
Design, build, and own large-scale data pipelines and ML data curation for multimodal (text, image, audio, video) model training. Partner with research teams to ingest, label, filter, augment, store, and ensure dataset quality, compliance, and scalability. Optimize distributed data processing for training, prototype dataset tools, and integrate research advances into production systems.
Top Skills: AWSAzureGCPHadoopPysparkPythonRaySparkSQL
Reposted One Month AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Artificial Intelligence • Big Data • Internet of Things • Software
The Senior Data Scientist will lead innovative data science efforts, leveraging advanced analytics, visualization, and insights from complex datasets to boost productivity.
Top Skills: PythonRScalaSQL
One Month AgoSaved
Remote or Hybrid
St. Louis, MO
180K-200K Annually
Senior level
180K-200K Annually
Senior level
Artificial Intelligence • Big Data • Machine Learning • Analytics • Business Intelligence • Consulting • Generative AI
Lead predictive modeling and causal inference initiatives for clients, developing models from exploratory analysis through production deployment, monitoring, and retraining. Apply GLMs, econometric methods, uplift modeling, propensity methods, and deep-learning forecasting. Process large-scale data with SQL and Spark, build models in Python, improve production reliability, and communicate findings to technical and business stakeholders in a consulting environment.
Top Skills: SparkPythonSQL
One Month AgoSaved
Remote
St. Louis, MO
148K-203K Annually
Senior level
148K-203K Annually
Senior level
Artificial Intelligence • Information Technology • Machine Learning • Marketing Tech • Software • Biotech • Design
Build marketing data science models and decision systems for spend allocation, channel measurement, forecasting, experimentation, and growth optimization. Unify marketing, retail, revenue, and product data; develop dashboards and analytical products; apply AI/ML and causal inference; and translate complex analysis into actionable recommendations for executives and cross-functional teams. The role also includes improving data quality, mentoring, documentation, and technical leadership.
Top Skills: AWSDatabricksDbtLlmsPythonSnowflakeSQL
Reposted One Month AgoSaved
In-Office or Remote
St. Louis, MO
135K-155K Annually
Senior level
135K-155K Annually
Senior level
Digital Media • News + Entertainment • Business Intelligence
Lead data science work embedded in the newsroom: identify high-impact problems, build and productionize predictive and explanatory models, own core metrics/measurement, apply causal inference and experimentation, translate findings for senior stakeholders, and mentor junior data team members to improve analytic standards and adoption.
Top Skills: AirflowBigQueryDbtGitPythonSnowflakeSQL
Reposted One Month AgoSaved
Remote or Hybrid
St. Louis, MO
138K-231K Annually
Expert/Leader
138K-231K Annually
Expert/Leader
Information Technology • Consulting
Lead end-to-end data science initiatives for commercial property or homeowners insurance: acquire and prepare data, build and validate predictive models, deploy and monitor production models, ensure governance and documentation, advise teams, and evaluate emerging ML/AI techniques to improve pricing, risk selection, and underwriting outcomes.
Top Skills: A/B TestingAWSAzureAzure DevopsGamma DistributionGCPGitGlmK-MeansPandasPartial Dependence PlotsPcaPoisson DistributionPythonScikit-LearnShapSQLTweedie DistributionXgboost
Reposted One Month AgoSaved
Remote
St. Louis, MO
76K-158K Annually
Senior level
76K-158K Annually
Senior level
Aerospace • Information Technology • Professional Services • Defense
Design and implement advanced ML models for real-time forecasting and decision support, ensure data provenance and lineage, integrate federated geospatial and multi-format data, produce ROM and quarterly cost/resource reports, and apply Agile sprint practices to deliver mission-aligned analytics for DoD/IC customers.
Top Skills: SparkDatabricksPythonPyTorchScikit-LearnTensorFlow
New

Track Smarter, Apply Better.

Ditch the spreadsheets. Organize your job search with our freeApplication Tracker.

Use For Free
Application Tracker Preview
Reposted One Month AgoSaved
Remote
St. Louis, MO
144K-299K Annually
Senior level
144K-299K Annually
Senior level
AdTech • Digital Media • Information Technology • Other
As a Senior Data Scientist at Yahoo Mail, you will enhance user growth strategies via product innovation, overseeing research projects and analytics.
Top Skills: BigQueryHadoopHiveLookerPythonSparkSQLTableau
Reposted One Month AgoSaved
In-Office
St. Louis, MO
Senior level
Senior level
Information Technology • Software • Cybersecurity • Defense
Lead development of scalable analytic solutions that transform complex intelligence data into actionable insights. Design and implement data pipelines, automation, data models, visualizations, and production-ready Python tools. Provide technical leadership, rapidly prototype solutions, and collaborate with multidisciplinary IC teams to modernize analytic workflows and support operational decision-making.
Top Skills: GeointIntelligence Community Data RepositoriesPython
Reposted One Month AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Healthtech
Build, ship, and own end-to-end ML models for vendor matching, order routing, and supply-chain optimization. Partner with data engineering to productionize models, quantify impact, document work, and implement decision logic components toward agentic AI in a fast-moving healthcare startup environment.
Top Skills: Agentic AiCausal InferenceGitMachine LearningOperations ResearchPythonReinforcement LearningSQL
Reposted One Month AgoSaved
Remote or Hybrid
St. Louis, MO
Senior level
Senior level
Information Technology • Database • Consulting
Lead development of time-series and econometric models (ARIMA, VAR, state-space, WLS, panel data) and Bayesian probabilistic frameworks. Use causal inference and stochastic processes to produce actionable insights, work with large datasets on Databricks, communicate results to stakeholders, and mentor junior team members.
Top Skills: A/B TestingArimaBayesian ModelingCausal InferenceDatabricksMachine LearningMarkov ChainsMlopsPanel Data ModelsPythonSarimaSQLState-Space ModelsStochastic ProcessesVarWls
Reposted One Month AgoSaved
In-Office or Remote
St. Louis, MO
Senior level
Senior level
Information Technology
Lead advanced analytics and ML projects: perform EDA, feature engineering, statistical modeling, and build/optimize production ML and Generative AI solutions (LLMs, embeddings, RAG). Collaborate with engineering and MLOps to deploy and monitor models, create visualizations and dashboards, translate insights for stakeholders, and mentor junior team members.
Top Skills: AWSAzureCi/CdDockerEmbeddingsGCPKubernetesLlmsMlflowMlopsPower BIPrompt EngineeringPythonPyTorchRagScikit-LearnSQLTableauTensorFlowXgboost
Reposted One Month AgoSaved
In-Office or Remote
St. Louis, MO
62K-217K Annually
Senior level
62K-217K Annually
Senior level
Agency • Information Technology
Design, build, and deploy production-grade generative AI applications: orchestrate multi-agent systems, implement advanced RAG with vector DBs, fine-tune and host LLMs, optimize GenAI workflows, and deliver scalable FastAPI-based backend services with Docker and monitoring.
Top Skills: Api SecurityAsynchronous ProgrammingCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLlm QuantizationLocal LlmsModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector DatabasesVector Search
Reposted One Month AgoSaved
In-Office or Remote
St. Louis, MO
71K-249K Annually
Senior level
71K-249K Annually
Senior level
Agency • Information Technology
Design, build, and deploy production generative AI applications: orchestrate multi-agent workflows, implement advanced RAG with vector databases, integrate/benchmark LLMs, fine-tune models, and deploy scalable FastAPI-based services with monitoring, CI/CD, and Dockerized production pipelines.
Top Skills: Async PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLlm QuantizationLocal Llm DeploymentModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchRagTensorFlowVector DatabasesVector Search
Reposted One Month AgoSaved
In-Office or Remote
St. Louis, MO
62K-217K Annually
Senior level
62K-217K Annually
Senior level
Agency • Information Technology
Design, build, and scale production Generative AI systems: multi-agent orchestration, advanced RAG with vector databases, LLM integration and fine-tuning, scalable FastAPI backends, Dockerized deployment, monitoring, and GenAI optimization for latency, cost, and reliability.
Top Skills: Async PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLocal Llm DeploymentMulti-Agent Systems (Mas)OpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector DatabasesVector Search
Reposted One Month AgoSaved
In-Office or Remote
St. Louis, MO
53K-188K Annually
Senior level
53K-188K Annually
Senior level
Agency • Information Technology
Design, build, and deploy production-grade generative AI systems: multi-agent orchestration, advanced RAG with vector databases, integrate/swap LLMs, fine-tune models, optimize prompts and latency, and containerize services with monitoring and CI/CD.
Top Skills: Api SecurityAsynchronous ProgrammingCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLocal LlmsModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchQuantizationRagTensorFlowVector Databases
Reposted One Month AgoSaved
In-Office or Remote
St. Louis, MO
53K-188K Annually
Senior level
53K-188K Annually
Senior level
Agency • Information Technology
Build, optimize, and scale production Generative AI applications. Design multi-agent systems and LangGraph workflows, implement advanced RAG with LlamaIndex and vector DBs, fine-tune and deploy LLMs, and create high-performance FastAPI async backends. Improve latency, cost, and reliability, containerize services with Docker, and manage monitoring, API security, and CI/CD for ML deployments.
Top Skills: Api SecurityAsync PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLlm Quantization/HostingLocal Model DeploymentModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector DatabasesVector Search
Reposted One Month AgoSaved
In-Office or Remote
St. Louis, MO
62K-217K Annually
Senior level
62K-217K Annually
Senior level
Agency • Information Technology
Design, build, and scale production Generative AI applications: multi-agent systems, advanced RAG pipelines, LLM integration and fine-tuning, scalable FastAPI backends, vector search, monitoring, and Dockerized deployments.
Top Skills: Async PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLocal LlmsLocal Model QuantizationModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector DatabasesVector Search
Reposted One Month AgoSaved
In-Office or Remote
St. Louis, MO
62K-217K Annually
Senior level
62K-217K Annually
Senior level
Agency • Information Technology
Design, build, and deploy production Generative AI applications: orchestrate multi-agent workflows, implement advanced RAG with vector DBs, integrate and fine-tune LLMs, develop scalable FastAPI/async backends, containerize with Docker, and optimize GenAI systems for latency, cost, and reliability.
Top Skills: Async PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLocal LlmsMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchRagTensorFlowVector DatabasesVector Search
Reposted One Month AgoSaved
In-Office or Remote
St. Louis, MO
79K-276K Annually
Senior level
79K-276K Annually
Senior level
Agency • Information Technology
Design, build, and scale production Generative AI applications including multi-agent systems, advanced RAG pipelines, and local/frontier LLM deployments. Implement high-performance backends with FastAPI and async Python, fine-tune and quantize models, integrate vector databases and retrieval systems, and deploy/monitor containerized AI services for reliability, latency, and cost optimization.
Top Skills: Async PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLocal Llm Quantization/HostingModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchRagTensorFlowVector Databases
All Filters
JobType
New Jobs
Job Category
Experience
Industry
Company Name
Company Size

Sign up now Access later

Create Free Account