Top Data Science Jobs in St. Louis, MO

Reposted 3 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Big Data • Analytics • Business Intelligence • Big Data Analytics
The Senior Data Scientist will design and deploy time-series forecasting models, collaborate with stakeholders, and operationalize models in cloud environments, focusing on demand planning across various industries.
Top Skills: AIArimaAzureData ScienceDemand ForecastingEtsGbmLightgbmMachine LearningPythonRandom ForestSarimaSQLTime-Series ModelingXgboost
Reposted 3 Days AgoSaved
Remote
St. Louis, MO
174K-174K Annually
Senior level
174K-174K Annually
Senior level
Edtech
Lead advanced analytics and ML for partner-facing teams: build end-to-end predictive models (churn, lead scoring, health scores), marketing attribution and mix models, and maintain ML lifecycle standards. Develop agentic workflows and Claude Skills to accelerate work, mentor analytics team, and translate model outputs into actionable insights for Sales, Marketing, and CX.
Top Skills: ClaudeClaude SkillsCursorLlm-Based AutomationsPrompt LibrariesPythonSQL
Reposted 3 Days AgoSaved
Remote or Hybrid
St. Louis, MO
160K-208K Annually
Senior level
160K-208K Annually
Senior level
AdTech • Digital Media • eCommerce • Marketing Tech • Mobile • Software
Design, iterate, and productionize ML models for recommendation, ranking, routing, and monetization. Lead A/B testing and causal measurement, build dashboards and analytics, define metrics, collaborate with Product and Engineering, and scale ML/analytics infrastructure and model lifecycle management.
Top Skills: APIsAWSDistributed SystemsHigh-Volume Data PipelinesPythonSQL
Reposted 3 Days AgoSaved
Remote
St. Louis, MO
120K-182K Annually
Senior level
120K-182K Annually
Senior level
Biotech
The Senior Associate Scientist will analyze and visualize data, collaborate on screening strategies, and validate hits for drug discovery using the EMMI platform.
Top Skills: LinuxMoePythonRdkitSchrodingerSpotfireSQL
14 Days AgoSaved
In-Office
St. Louis, MO
Senior level
Senior level
Information Technology • Software • Consulting
Lead development of mission-ready data exploitation and geospatial analytics solutions using Python. Integrate web APIs, build dashboards and visualizations, query relational databases, use GIS tools, and produce technical documentation. Operate independently at senior level, guide junior staff, collaborate across Intelligence Community analysts, and advise government leadership.
Top Skills: Arcgis ProArcpyBokehDashGdalGitGitlabMatplotlibPanelPlotlyPythonQgisRelational DatabasesSeabornSQLStreamlitTableauWeb Apis
Reposted 4 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Artificial Intelligence • Information Technology • Professional Services • Consulting
The Senior Data Scientist will design and deploy machine learning models, analyze complex datasets, develop analytical solutions, and mentor junior team members in a remote environment.
Top Skills: Amazon AwsDatabricksGoogle GcpLookerAzurePower BIPythonPyTorchRScikit-LearnSnowflakeSparkSQLTableauTensorFlow
Reposted 4 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Security
The Geospatial Scientist leads data management initiatives, oversees data governance, and ensures quality and compliance of geospatial data for DHS.
Top Skills: Arcgis EnterpriseEsri Geoportal ServerGeoplatform.GovGis Systems
Reposted 4 Days AgoSaved
Remote
St. Louis, MO
100K-132K Annually
Senior level
100K-132K Annually
Senior level
Healthtech • Social Impact
Build, deploy, monitor, and document predictive models and analytical reports; translate findings for non-technical stakeholders; ensure model quality, fairness, and explainability; collaborate with data engineers and train staff on data literacy; support production ML infrastructure on AWS.
Top Skills: AWSAws SagemakerDeployment PipelinesModel RegistriesPandasPythonRRedshiftScikit-LearnSnowflakeTidyverseVersion Control
Reposted 4 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Artificial Intelligence • Healthtech • Software • Biotech
Design and validate clinical and biomarker data pipelines, perform source-to-target mappings (e.g., EHR to data model), extend ontologies and vocabularies, ensure data quality, evaluate informatics tools, and support data architecture and analysis workflows for a regulatory-grade platform.
Top Skills: Controlled VocabulariesEhrIcdLoincOntologiesPythonRSnomedSQLValue Sets
Reposted 4 Days AgoSaved
In-Office or Remote
St. Louis, MO
Senior level
Senior level
Logistics • Software
Lead development of digital twin and simulation models for warehouse operations, deploy AI-driven decision systems, build forecasting and optimization models, validate experiments linking operational metrics to financial impact, and partner with engineers, operations, and external AI/academic partners to scale innovations across fulfillment networks.
Top Skills: Agentic AiAnylogicContinuous SimulationDigital TwinDiscrete-Event SimulationFlexsimLlmsMachine LearningOmsOptimizationPythonRSimioSQLWms
Reposted 4 Days AgoSaved
In-Office or Remote
St. Louis, MO
124K-165K Annually
Senior level
124K-165K Annually
Senior level
Digital Media • Fintech • Information Technology • Machine Learning • Financial Services • Cybersecurity • Automation
Develop, implement, and maintain ALM and CCAR/PPNR models for balance sheet forecasting. Build customer behavior, prepayment, and deposit models; monitor performance, perform backtesting and sensitivity analysis; collaborate with Model Risk, Market Risk, Treasury, and validation teams; prepare documentation and materials for governance and senior leadership; support balance sheet optimization and regulatory initiatives.
Top Skills: AdcoBancwareBlack KnightBlackrockBloombergEconomy.ComEmpyreanFredNovantasPythonQrmR
Reposted 4 Days AgoSaved
Remote
St. Louis, MO
140K-150K Annually
Senior level
140K-150K Annually
Senior level
Marketing Tech • Mobile • Software
The Senior Data Scientist will analyze customer data, design experiments, build models, and support data-driven decision-making across product, marketing, and customer experience teams.
Top Skills: BigQueryDbtPythonSnowflakeSQL
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Reposted 4 Days AgoSaved
Remote
St. Louis, MO
Expert/Leader
Expert/Leader
Healthtech
As a Lead Data Scientist, you will shape data strategy, develop predictive models, analyze healthcare datasets, and collaborate with teams to enhance MDCalc's clinical decision tools.
Top Skills: LookerNumpyPandasPythonRScikit-LearnSQLStatsmodelsTableau
Reposted 4 Days AgoSaved
Remote
St. Louis, MO
160K-195K Annually
Senior level
160K-195K Annually
Senior level
Food
Lead retention and churn efforts by building survival and lifecycle-state models, classifying churn reasons, creating personalized win-back and next-best-action interventions, optimizing offers/promos, designing uplift experiments, and owning production model lifecycle, monitoring, and MLOps across Product, CRM, Marketing, and Engineering.
Top Skills: A/B TestingChatgptCi/CdClaudeContainerizationDeep LearningEmbeddingsGradient BoostingMlopsModel RegistryOrchestrationPandasPythonRecommender SystemsScikit-LearnSQLSurvival ModelingUplift/Causal Inference (Econml)
Reposted 4 Days AgoSaved
Remote
St. Louis, MO
183K-224K Annually
Senior level
183K-224K Annually
Senior level
Fintech
The Principal Data Scientist will design, develop, and deploy machine learning models, innovating methodologies and collaborating across teams to enhance financial decision-making and risk management.
Top Skills: AirflowBentomlChalkDvcKubernetesMachine LearningMlflowNumpyPandasPydata StackScikit-LearnSpark
Reposted 4 Days AgoSaved
Remote
St. Louis, MO
158K-193K Annually
Senior level
158K-193K Annually
Senior level
Healthtech • Information Technology
The Senior Data Scientist leads data-driven initiatives, optimizing analytics for business decisions, mentoring staff, and ensuring data quality across healthcare projects.
Top Skills: GCPMatlabPlsqlPythonPyTorchRSQLTensorFlow
Reposted 4 Days AgoSaved
Remote
St. Louis, MO
137K-152K Annually
Senior level
137K-152K Annually
Senior level
Healthtech • HR Tech • Sales • Social Impact • Software
As a Senior Data Scientist, you will identify business opportunities, build machine learning solutions, partner cross-functionally, and translate analyses into actionable insights.
Top Skills: Business Intelligence ToolsMachine LearningPythonRSQL
Reposted 4 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
AdTech
Lead development of graph-based identity resolution for CTV advertising: design models and validation, analyze large identity datasets with distributed tools, productionize data-science workflows, partner with engineering/product, and apply privacy-by-design while leveraging LLMs and AI-assisted development.
Top Skills: BigQueryClaude CodeCursorDataprocGithub CopilotGoogle Cloud PlatformGoogle Cloud Storage (Gcs)KafkaLlmsPythonScalaSparkSQL
Reposted 5 Days AgoSaved
Remote
St. Louis, MO
143K-304K Annually
Expert/Leader
143K-304K Annually
Expert/Leader
Software • Quantum Computing • Metaverse • Infrastructure as a Service (IaaS)
Lead end-to-end data science and AI engagements: design, develop, deploy and evaluate models, mentor teams, partner with stakeholders, drive adoption, and apply Responsible AI to deliver measurable business impact.
5 Days AgoSaved
Remote
St. Louis, MO
118K-162K Annually
Senior level
118K-162K Annually
Senior level
Healthtech
Design, validate, and deploy predictive models using claims, clinical, pharmacy, and lab data to improve population health, utilization management, and care quality. Partner with clinical and business teams, evaluate model performance, scale analytical approaches, and communicate insights to technical and non-technical stakeholders.
Top Skills: Deep LearningEpicNlpPysparkPythonRSASSpark
5 Days AgoSaved
Remote
St. Louis, MO
138K-230K Annually
Senior level
138K-230K Annually
Senior level
Financial Services
Lead the intelligence layer atop the data lakehouse: design and run causal experimentation, build predictive and forecasting models, own model evaluation and monitoring, deploy and maintain models on Databricks/MLflow, set technical direction for data science, and partner closely with data engineers, AI engineers, and product. Use AI development tools daily.
Top Skills: AgentsClaude CodeCursorData Vault 2.0DatabricksExperimentation PlatformsGradient BoostingLangfuseLlmsMedallion LakehouseMlflowPythonScikit-LearnSQL
Reposted 5 Days AgoSaved
Remote
St. Louis, MO
180K-220K Annually
Senior level
180K-220K Annually
Senior level
Fintech • Software • Financial Services
The Lead Data Scientist will enhance analytics through predictive modeling and data engineering, focusing on quality, feature generation, and continuous learning.
Top Skills: DashGoogle Data StudioLookerPower BIPythonSQLStreamlitTableau
Reposted 5 Days AgoSaved
Remote
St. Louis, MO
200K-200K Annually
Senior level
200K-200K Annually
Senior level
Fintech
As a Pricing Data Scientist, you'll develop and validate pricing models for alternative assets, collaborate with engineers, and enhance valuation accuracy through data insights.
Top Skills: AWSGCPLightgbmMlflowPandasPythonPyTorchScikit-LearnSQLTensorFlowXgboost
Senior level
Pharmaceutical
Develop and validate SDTM and ADaM datasets using R following CDISC standards, support TLF generation in R/SAS, perform QC and reconcile data issues, collaborate with statisticians and clinical teams, document workflows, and support automation of R-based pipelines for clinical trial deliverables.
Top Skills: AdamCdiscRSASSdtm
Reposted 6 Days AgoSaved
In-Office or Remote
St. Louis, MO
120K-261K Annually
Senior level
120K-261K Annually
Senior level
Software • Quantum Computing • Metaverse • Infrastructure as a Service (IaaS)
Lead customer-facing data science engagements: manage data acquisition/cleaning, develop and evaluate scalable models, drive modeling best practices, contribute thought leadership, write extensible code, and define solution and business strategy with cross-functional teams.
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