Top IT Jobs in St. Louis, MO

Design, develop, and maintain high-performance Scala/Java server-side applications and RESTful APIs. Work on distributed systems, ensure data integrity and security, write unit tests, optimize performance, participate in design reviews, and mentor junior engineers while supporting CMS mission requirements.

Administer Epic’s corporate identity, access, endpoints, applications, devices, and employee IT support. Manage onboarding and offboarding, access reviews, authentication and device standards, MDM provisioning, asset inventories, procedures, and audit evidence. Support SOC 2 or similar compliance activities, security reviews, and incident response while partnering with infrastructure and people operations. This is a fully remote, US-based role supporting a global engineering team.

Leads multidisciplinary distribution systems engineering teams supporting large-scale telecommunications and network infrastructure modernization. Responsibilities include supervising engineers, technicians, subcontractors, and agency labor; coordinating government stakeholders, base access, schedules, materials, and deployments; validating designs and engineering deliverables; leading reviews and planning; mitigating risks; and supporting program execution. The role requires extensive OSP/ISP, fiber optic, telecommunications room, Air Force and Space Force standards experience, an active Secret clearance, and extensive travel to Eielson Air Force Base.

Lead enterprise solution architecture and modernization of legacy IBM mainframe financial applications. Analyze current-state systems, design cloud-enabled future-state architectures, map business processes, and guide migrations involving COBOL, JCL, CICS, DB2, and VSAM. Provide technical leadership across integration, data migration, interoperability, documentation, testing, and deployment. Collaborate with financial agencies and development teams to implement modern solutions using Java, Spring Boot, APIs, microservices, databases, cloud platforms, and DevSecOps practices.

Designs, implements, and sustains enterprise WAN/LAN/CAN networks for an Intelligence Community customer. Leads modernization, troubleshooting, traffic analysis, test plans, architecture diagrams, site surveys, and installs satellite communications while adhering to security and compliance requirements.

Manage, tune, and secure PostgreSQL databases including HA, backups, migrations, monitoring, and schema design. Support upgrades, patching, alerts, documentation, and on-call rotations while collaborating with developers and evaluating tools.

Support systems engineering for enterprise-scale, multi-site environments: document requirements, produce architecture artifacts, integrate and test hardware/software components, manage service tickets, coordinate across contracts, and produce technical presentations and diagrams.

Lead administration of Microsoft 365, Google Workspace, SaaS applications, Azure identity, and cloud infrastructure in a fully cloud-based organization. Provide Level 2/3 service desk escalation, execute migrations and cybersecurity projects, establish IT service processes, manage assets and vendors, and support onboarding, offboarding, incident response, change management, and M&A initiatives. The role partners with IT leadership and may help build and manage a growing internal technical team.

The Senior Clinical Trials IT Business Analyst bridges Clinical Development and IT, optimizing clinical trial technologies and managing system implementations, validations, and stakeholder engagement.

Leads enterprise architecture for Biogen’s Veeva ecosystem across Development, Quality, Regulatory, Safety, and Commercial functions. Translates business needs into scalable Veeva configurations and integrations, governs target-state architecture and platform standards, reviews solution designs, and oversees implementation and release planning. Mentors configuration teams, drives cross-vault consistency, manages architecture governance, aligns with Veeva product roadmaps, and advises IT leadership on platform strategy, investments, regulatory compliance, and business objectives.

Leads the design, development, integration, deployment, and operation of large-scale Zero Trust security solutions for DoD environments. Creates system architecture blueprints, selects technologies, integrates distributed systems across on-premise and cloud environments, optimizes performance, ensures compliance with DoD requirements, and leads engineering teams. Diagnoses system issues, implements solutions, and produces architecture documentation while supporting installation, migration, and configuration activities across multiple client locations.

Leads the architecture, design, integration, deployment, and operation of large-scale Zero Trust security solutions for DoD environments. Creates system blueprints, selects technologies, integrates distributed systems across on-premises, cloud, and hybrid environments, optimizes performance, resolves system issues, and ensures compliance with DoD requirements. Leads engineering teams, supports installation and migration at multiple locations, and documents architecture and implementation decisions.

Sell radiology IT solutions by building strategic account plans, managing long technical sales cycles, maintaining a 3-5× quota pipeline, forecasting in Salesforce, partnering with marketing/inside sales, and representing the company at industry conferences.

Lead requirements analysis, design, and delivery of Cass TIS solutions. Document requirements, conduct gap analysis, define acceptance criteria, coordinate teams, create project plans, and mentor junior analysts to ensure successful deployments.

Leads business analysis for enterprise applications and reporting initiatives. Translates stakeholder needs into requirements and functional or technical specifications, partners with IT on scalable solutions, manages project scope and risks, maintains process documentation, supports UAT and change readiness, and drives process standardization. Establishes business analysis standards and best practices across a growing, multi-location organization.

The IT Manager, Product Owner - Finance drives financial process transformations, prioritizes product backlogs, and manages stakeholder relationships to ensure high-quality delivery of financial systems solutions.

Develop and maintain Digital Workplace tools, working closely with teams, performing testing, debugging, and technical research. Requires web development experience and familiarity with modern software architectures.

Lead a team to design, build, and operate scalable, secure platform and MLOps capabilities on GCP and hybrid cloud. Drive DevSecOps, CI/CD, telemetry, and platform modernization to accelerate AI/ML and software delivery while managing delivery, budgets, vendors, and stakeholder alignment.

The IT Project Manager will oversee project planning, implementation, and client interactions while ensuring compliance with federal and state regulations in the public sector.

The IT Project Manager will lead public sector ERP migration projects, ensuring high-quality deliverables and strategic alignment while collaborating with various stakeholders.

Lead global IT sourcing strategy and a multi-year technology modernization agenda. Manage $450M spend, strategic supplier relationships, governance, risk, and value delivery. Oversee category management (cloud, software, infrastructure, cyber), negotiations with hyperscalers and SaaS vendors, stakeholder engagement, and build a high-performing sourcing organization.

Lead technical onboarding and ongoing support for remote connectivity at dental practices. Configure and troubleshoot VPNs, Splashtop, remote desktop, printers/scanners, and network authentication. Manage implementations, validate connectivity and integrations, coordinate with clients and third-party IT, escalate complex issues, document processes, and contribute to improvements in remote access infrastructure and automation.

Lead planning, execution, and delivery of enterprise technology projects. Manage scope, timelines, budgets, resources, risks, vendors, stakeholders, and communications across Agile, Scrum, and Waterfall environments. Oversee software development, technology implementations, cloud transformation, application modernization, and concurrent project priorities while ensuring business and technology objectives are achieved.

Build and operate internal IT systems across identity, endpoints, Google Workspace, Slack, SaaS governance, and automation. Own Okta access engineering, Workspace ONE macOS fleet management, lifecycle workflows, compliance controls, audit evidence, and technical escalations. Partner with Security, Engineering, People, and Finance to improve security, reliability, and scalability while reducing manual IT support through automation.

Own identity and access engineering in Okta, macOS endpoint management in Workspace ONE, Google Workspace and Slack administration, SaaS governance, and IT automation. Build onboarding, deprovisioning, access reporting, device compliance, and audit-evidence workflows. Serve as a technical escalation point for identity, endpoint, access, and internal infrastructure issues while translating security and compliance requirements into durable IT controls.