Top IT Jobs in St. Louis, MO

Manage multi-site IT support operations for a manufacturing organization: lead L1/L2 teams, resolve hardware/software issues, oversee infrastructure, enforce cybersecurity, coordinate vendors, manage imaging and deployments, document systems, and align IT with production goals.

Design, develop, test, and analyze operating-systems-level and embedded systems software. Define operational specifications, formulate and analyze software requirements, and apply computer science, engineering, and mathematical principles to mission-critical government projects.

Manage and deliver data center IT infrastructure projects (GPU servers, networking, storage). Coordinate stakeholders, lead technical discussions, resolve operational issues, document plans and risks, and support automation and process improvements.

Provide front-line IT service desk support for global employees: triage and resolve tickets, manage Okta and Google Workspace lifecycles, deploy and troubleshoot macOS and mobile devices via Jamf, support VPN/Cloudflare One remote access, use AI tools to automate workflows, assist onboarding/offboarding, and train employees on technologies.

Lead and own global hosting and infrastructure operations across cloud (Azure), co-location, and hybrid environments. Manage major incident response, reliability, capacity planning, M&A infrastructure integrations, core infrastructure projects, security/compliance (SOC2, GDPR), and a distributed hosting operations team. Drive observability, automation, and DR readiness while partnering with enterprise architecture, security, and senior leadership to deliver scalable, secure hosting services.

Design and implement Epic hospital billing and revenue cycle solutions. Gather business requirements, lead technical direction for projects, support claims/denials and cash posting/reconciliation, create process mappings, measure project outcomes, mentor IT staff, and coordinate with business stakeholders to achieve operational excellence.

Lead IT and cybersecurity governance, risk, and compliance programs including IT SOX/ITGC execution, ERM for IT risks, audit liaison, policy authoring, KRI/KPI tracking, GRC tool integration, third-party risk review, and people leadership to improve control maturity and regulatory alignment.

Provide frontline and advanced application support for radiology imaging workflows: incident triage, user provisioning, configuration changes, DICOM troubleshooting, monitoring interfaces, coordinating with networks/storage/vendors, maintaining SOPs and knowledge base, delivering end‑user training and on‑call doctor support to meet SLAs.

As an IT Support Engineer, you'll manage frontline IT support and endpoint operations, improve access workflows, and collaborate with Security and Engineering. Responsibilities include triaging issues, onboarding, and maintaining system documentation.

Design and automate compliance systems to enhance efficiency in audit readiness. Collaborate with teams to integrate tools and optimize processes.

The IT Support Engineer will handle frontline IT support, device management, and identity access workflows, ensuring a seamless employee experience.

The Senior IT Engineer will design, build, and maintain integrations across diverse technology stacks, ensuring data flow and operational efficiency while mentoring junior staff and collaborating with various engineering teams.

The Senior Enterprise Architect will lead CRM architecture for Cengage, focusing on Salesforce integration and ensuring scalable enterprise capabilities, while mentoring teams and reducing technical debt.

Lead complex IT initiatives across application development, infrastructure, cybersecurity, and data platforms while collaborating with various stakeholders.

Plan, conduct, and document onsite and virtual site visits and audits of transplant hospitals and OPOs to assess compliance with OPTN bylaws and regulations. Collect evidence, draft site visit reports, coordinate logistics with stakeholders, track follow-up actions, and support patient-safety investigations and corrective action monitoring.

Lead and deliver infrastructure and cloud migration projects (IaaS/PaaS), manage multiple project teams, stakeholder communications, budgets, risks, vendor coordination, and project governance from planning through execution.

Senior IT leader responsible for leading a 30+ developer application development organization across multiple insurance lines. Owns modernization, legacy reduction, AI-enabled application delivery, cloud architecture, vendor evaluations, and roadmap alignment with business stakeholders while developing engineering managers and driving cross-line transformation.

Evaluate IT infrastructure systems by conducting security assessments and developing reports. Ensure compliance with NIST standards while advising on data protection.

Perform end-to-end FedRAMP assessments for cloud service providers: interview SMEs, review IaaS architectures (AWS/Azure/OCI), validate NIST SP 800-53 controls, analyze vulnerabilities, verify encryption and configurations, draft deliverables, and mentor project team members.

Perform end-to-end FedRAMP assessments: interview CSP SMEs, walkthrough cloud architectures (AWS/Azure/OCI), evaluate NIST SP 800-53 controls, validate configurations and vulnerabilities, draft deliverables, train and mentor team members, and support practice development.

Lead FDIC-focused IT services strategy and business development. Build relationships with FDIC decision makers, drive capture and proposal efforts, lead program teams, and align GDIT capabilities to client mission needs while managing delivery and growth.

Senior Java Developer on an agile team to design, develop, test, and deploy enterprise-grade Java/J2EE web applications. Ensure performance, security, scalability, maintain documentation, review requirements, propose solutions, and improve SDLC through TDD, CI/CD automation, code reviews, and collaboration with architects and stakeholders.

Advise and shape GDIT's NASA strategy, build stakeholder relationships, guide technical solutions and capture efforts, anticipate NASA needs, support business growth, and mentor senior leaders to ensure mission delivery.

Lead IT strategy and operational delivery for Department of State Consular Affairs engagement. Build executive relationships, drive capture and proposal efforts, direct large teams, implement strategic initiatives, and ensure successful program delivery while supporting growth of GDIT's portfolio.

Provide senior technical leadership and architectural oversight for large-scale EHR ecosystems. Define enterprise engineering strategy and roadmaps, ensure interoperability, scalability, availability, and cybersecurity, lead architectural governance and incident RCA, mentor engineering teams, coordinate with product owners and integrators, evaluate emerging technologies, and support proposals and customer engagements.