Top IT Jobs in St. Louis, MO

Process payroll accurately and confidentially, including timekeeping, wages, overtime, bonuses, taxes, deductions, payments, records, and reporting. Resolve payroll discrepancies and respond to employee and management questions. Maintain updated payroll records, calculate unemployment and severance payments, and ensure compliance with relevant legislation and regulations.

Build and deploy AI/ML solutions from prototype through production for CMS, including generative AI, LLMs, RAG, intelligent classification, knowledge management, agentic frameworks, and enterprise integrations. Evaluate AI coding tools, establish AI/ML roadmaps, scale adoption, mentor data scientists, and translate technical concepts for stakeholders and leadership.

Provide global IT support across hardware, software, identity, networking, cloud applications, onboarding, device provisioning, access management, endpoint administration, and asset tracking. Administer workplace systems including Okta, Google Workspace, and Kandji or Jamf. Troubleshoot macOS and Windows environments, maintain documentation and inventories, support security and compliance activities, and build automations to improve IT workflows and employee experience.

Provide technical support to a globally distributed workforce across hardware, software, identity, networking, cloud applications, and endpoint systems. Support onboarding, offboarding, device provisioning, access management, asset tracking, documentation, compliance activities, and security best practices. Troubleshoot macOS and Windows environments, escalate complex issues, and improve IT processes through automation. Collaborate with People, Security, Legal, Finance, and Engineering while exploring AI productivity tools and emerging workplace technologies.

Serves as the primary IT contact for business, executive, factory, and manufacturing stakeholders. Translates business needs into IT requirements, manages service portfolios, roadmaps, investments, programs, and projects, and governs service providers. Handles escalations, service-level agreements, performance reporting, improvement initiatives, and executive-critical support. Ensures IT solutions align with business objectives, budgets, timelines, quality standards, and enterprise architecture while supporting technology adoption and end-user training.

IT Development Program interns gain hands-on experience contributing to healthcare technology projects across data analytics, technical product management, digital engineering, and cybersecurity. Responsibilities include developing digital solutions, solving real-world technology challenges, collaborating globally, and building technical, leadership, communication, and problem-solving skills. The internship lasts at least 10 weeks during Summer 2027 and is based in Waukesha, Wisconsin, or remotely within the United States.

Develops and closes IT staffing opportunities with pharmaceutical, biotech, medical device, and healthcare research organizations. Responsibilities include prospecting, client discovery, relationship management, account planning, revenue forecasting, market intelligence, and full-cycle sales. The role partners with recruiting teams to deliver specialized technology talent and advises clients on hiring needs, compensation trends, regulated IT environments, and workforce strategy.

Leads the IT Strategic Governance and Delivery Office, overseeing project portfolios aligned with business goals. Manages planning and delivery of multiple IT initiatives, governance, budgets, timelines, quality, stakeholder relationships, process improvement, KPIs, and operational agreements. Drives cross-functional collaboration, continuous improvement, and strategic change while managing, coaching, and developing a team of six.

Leads infrastructure engineering strategy, modernization, project delivery, automation, and operational readiness across hybrid AWS, Azure, on-premises, networking, identity, Microsoft 365, and endpoint platforms. Establishes engineering standards, architecture patterns, security and resilience practices, Infrastructure as Code, CI/CD, monitoring, documentation, and support handoffs. Manages infrastructure projects, vendors, budgets, risks, and executive communications while leading, coaching, and developing an infrastructure engineering team.

Leads and develops the internal IT helpdesk and systems administration team, shifting operations from reactive support to proactive service delivery. Owns IT roadmaps, cross-functional projects, vendor relationships, authentication and access standards, disaster recovery, security improvements, and process automation. Establishes measurable KPIs and audit-ready onboarding and offboarding workflows while improving documentation, service levels, workload visibility, and operational accountability.

Supports IT governance, risk, privacy, and compliance programs by maintaining policies, coordinating audits, assessing technology and vendor risks, reviewing contracts, and tracking remediation. Manages privacy documentation including data inventories and processing records, evaluates AI solutions against relevant frameworks, audits access and IT assets, administers cybersecurity awareness training, and partners with Legal, Security, IT, People, and Procurement to embed compliance requirements in business initiatives.

The IT Business Analyst gathers and translates business requirements into technical solutions, partners with stakeholders and product owners, manages backlogs and roadmaps, and supports project delivery. The role creates requirements and UAT documentation, tracks software development, coordinates production issue resolution, and administers Genesys Cloud contact center capabilities including routing, IVR, queues, reporting, dialers, and workflows. It also identifies process improvements and serves as a subject matter expert across supported products and programs.

Advise mid-market clients on technology and AI strategy, build 3-5 year IT roadmaps, engage C-suite to prioritize IT investments, design Microsoft-stack solution architectures, guide AI adoption and governance, optimize IT budgets/staffing, lead audits and special projects, and support pre-sales to generate consulting engagements.

Coordinates data platform incident response, triage, escalation, root cause analysis, problem management, post-incident reviews, and operational improvements. Maintains runbooks, documentation, metrics, dashboards, and stakeholder communications. Implements and monitors security controls, supports security incident response, vulnerability remediation, compliance audits, regulatory reporting, disaster recovery exercises, and cross-functional coordination across data, cloud, infrastructure, DevSecOps, application, and governance teams.

Plans, executes, and reports on information systems control assessments for federal financial systems. Evaluates cybersecurity, access, change management, and segregation-of-duties controls across SAP and non-SAP enterprise applications. Applies FFMIA, GAO, FISCAM, Federal Audit Manual, OMB Circular, and federal accounting requirements. Produces working papers, summary reports, detailed findings, and actionable recommendations while supporting DoD/DLA programs.

Provides technical leadership for enterprise Identity Governance solutions, including architecture, risk assessment, automation, systems integration, application development, and secure access. Designs and implements identity systems across multi-platform environments using Oracle IAM technologies, LDAP, databases, operating systems, application servers, cloud infrastructure, and web/API technologies. Supports DoD and federal customers in an Impact Level 5 Oracle Cloud environment and requires advanced systems engineering expertise, certifications, and a Tier 3 or IT-II designation.

The Network Engineer plans, tests, documents, and implements network hardware, software, configuration, routing, and interoperability changes across DLA WAN, DISN, cloud, core, and remote networks. Responsibilities include developing implementation and assessment plans, conducting laboratory evaluations, creating network designs and maps, preparing test and after-action reports, defining requirements, analyzing telecommunications needs, supporting network services, and recommending routing and configuration improvements. The role requires hybrid onsite work and SIPR-related support.

Provides executive and employee communications during major IT incidents, translates complex technical topics into clear messages, develops presentations and communication strategies, supports communications tools, maintains brand standards, monitors media trends, and produces video content. Advises stakeholders and executives while coordinating Systemwide IT communications and strategic storytelling. The role requires strong writing, editing, storytelling, collaboration, technical aptitude, and the ability to work independently under pressure.

Lead and coordinate IT and security audits across cloud infrastructure, application security, IAM, vendor risk, and blockchain products; shape audit roadmap; produce executive- and Board-level reports; drive remediation and validate corrective actions; partner with technology leaders and mentor audit staff.

Lead end-to-end IT and security audits across cloud infrastructure, application security, IAM, vendor risk, and blockchain products. Plan and execute fieldwork, produce evidence-based reports for senior leaders and the Audit Committee, mentor junior auditors, validate remediation, and partner with Engineering and Security to improve controls while maintaining audit independence.

Supervise and perform SOC examinations, HITRUST certifications, and ISO assessments. Lead a team, review workpapers, analyze controls, and assess internal deficiencies while ensuring compliance with quality control policy.

Coordinates testing for Epic applications and integrated healthcare systems, including test planning, user acceptance testing, defect management, upgrades, implementations, documentation, and compliance. Provides tier-2 application support, resolves complex system issues, supports optimization and enhancements, collaborates with stakeholders and vendors, facilitates governance meetings, and mentors junior analysts. The role also requires advanced AI literacy, healthcare operations knowledge, and independent leadership across application support and delivery initiatives.

Drive sales growth for LG IT solutions across the Central Region through consultative selling, territory planning, account development, and partner collaboration. Build enterprise and commercial customer relationships, manage opportunities from discovery through close, coordinate pricing and forecasting, maintain Salesforce pipeline data, and achieve revenue and sales objectives. The role involves executive engagement, customer presentations, trade shows, and approximately 70–75% regional travel.

Lead the planning, execution, monitoring, and delivery of enterprise technology projects. Manage scope, timelines, budgets, resources, risks, vendors, and stakeholder communications while coordinating cross-functional teams across Agile, Scrum, and Waterfall environments. Projects may include software development, cloud transformation, application modernization, and enterprise technology implementations. Ensure business and technology objectives are achieved across multiple concurrent initiatives.

Administer and secure DOE’s Oracle Fusion Middleware environment, serving as the primary SME for WebCenter, Enterprise Manager, OID/OAM, and SSL/TLS encryption. Responsibilities include installation, configuration, patching, tuning, monitoring, identity and access management, certificate lifecycle management, compliance with NIST and FedRAMP controls, audit support, remediation, and backup support for broader Oracle technologies. The role also requires collaboration with program managers, security teams, and product SMEs.