Top IT Jobs in St. Louis, MO

Lead design, architecture, and engineering of Cross Domain Solutions (CDS). Analyze alternatives, create complex design packages, gather/validate stakeholder requirements, coordinate implementation, support accreditation and operational CDS environments, mentor engineers, and provide technical inputs for modernization and strategy.

Designs, implements, and maintains enterprise Linux infrastructure on-prem and virtualized. Automates deployments with Ansible and scripting, manages RHEL/Satellite/ Capsule, supports Nutanix virtualization, monitoring (Grafana/Zabbix), authentication (OAuth/SSO), and troubleshoots complex performance and integration issues. Participates on SAFe/Scrum teams, documents architectures and automation, and drives operational improvements.

Designs, implements, and sustains enterprise WAN/LAN/CAN networks for an Intelligence Community customer. Leads modernization, troubleshooting, traffic analysis, test plans, architecture diagrams, site surveys, and installs satellite communications while adhering to security and compliance requirements.

Manage, tune, and secure PostgreSQL databases including HA, backups, migrations, monitoring, and schema design. Support upgrades, patching, alerts, documentation, and on-call rotations while collaborating with developers and evaluating tools.

Provide computer system validation and assurance support for cGMP-regulated systems. Create, review, execute, and document validation deliverables (IQ/OQ/PQ), coordinate revalidation, assess periodic reviews, and liaise with QA, IT, Engineering and business stakeholders to ensure compliance with GAMP, cGMP, 21 CFR Part 11, EU Annex 11 and ISO standards.

The role involves managing enterprise systems, providing operational support, troubleshooting, designing user-centric solutions, and ensuring excellent customer service.

The role involves leading business development for IT solutions in federal contracting, leveraging relationships to identify opportunities and influence procurement strategies, while collaborating with various teams to drive success.

Lead information security governance, risk, and compliance programs. Manage cross-functional teams, SOC 2 Type II audits, regulatory engagements, enterprise data security and governance, incident communications, information security questionnaires, KPI/KRI reporting, and mentor junior staff to ensure regulatory and standards alignment.

The Manager of IT Engineering leads IT operations including identity management, SaaS, endpoint management, and internal tooling. This role ensures service quality and scalability for a remote workforce.

Support and enforce NIST/CMMC-aligned security controls; monitor SIEM/EDR and perform incident triage and response; manage Windows/AD environments; conduct vulnerability scanning and remediation; protect and classify FCI/CUI; support audits and control validation; maintain compliance documentation; collaborate with IT and business teams and communicate security risks to technical and non-technical stakeholders.

Manage internal IT infrastructure and developer operations while leading frontend web work. Run developer standups, own sprint planning in ClickUp, triage requests, perform hands-on frontend fixes (HTML/CSS/JS), manage AWS resources, administer Google Workspace and Okta SSO, oversee VPN and endpoint security, and coordinate QA and deployments across web properties.

Provide 2nd/3rd shift IT support for a remote workforce, focusing on macOS and Apple device troubleshooting, Google Workspace and Okta administration, MDM and asset management, ticketing, documentation, AI-enabled workflow automation, and collaboration with IT/security for endpoint hygiene and incident escalation.

Provide hands-on end-user IT support: troubleshoot OS/software, respond to tickets, apply patches, manage user accounts via Okta, configure MDM-managed mobile devices, and support Slack and Google Workspace integrations.

Provide tier 1 technical support for desktop hardware, OS, and applications via phone, email, and walk-ups; troubleshoot, document solutions in a knowledge base, maintain software license compliance, track metrics, and assist IT staff with escalations and other duties.

Lead research and advisory work on enterprise IT and AI strategy; produce thought leadership and actionable insights for CIOs and C-suite; advise clients, present at events, support sales, mentor analysts, and drive research agenda and process improvements.

The IT Manager, Product Owner - Finance drives financial process transformations, prioritizes product backlogs, and manages stakeholder relationships to ensure high-quality delivery of financial systems solutions.

Develop and maintain Digital Workplace tools, working closely with teams, performing testing, debugging, and technical research. Requires web development experience and familiarity with modern software architectures.

The IT Project Manager will oversee project planning, implementation, and client interactions while ensuring compliance with federal and state regulations in the public sector.

The IT Project Manager will lead public sector ERP migration projects, ensuring high-quality deliverables and strategic alignment while collaborating with various stakeholders.

Serve as the primary IT–business liaison, owning executive relationships, technology strategy, vendor management, and prioritization of IT/AI initiatives. Drive modernization, cost/benefit analyses, budgeting, continuous improvement, and successful deployment of technology solutions across business units.

Design, deploy, and maintain a secure cloud-native Enterprise Data Warehouse using DevSecOps practices. Build and operate automated CI/CD pipelines, IaC, containerized workloads, security/compliance integrations, continuous monitoring, vulnerability management, and change-control. Document processes, provide training, coordinate standards across stakeholders, and produce metrics to drive improvement.

Design, modernize, and optimize hybrid cloud and legacy relational databases (Informix, DB2, MySQL, Oracle, PostgreSQL). Collaborate with engineers and security teams to implement migrations, performance tuning, data modeling, SQL/PLSQL development, automation, and DevSecOps practices to support cloud adoption and mission-critical operations.

Lead delivery and oversight of internal and client projects, ensuring on-time, on-budget completion. Manage resources, risks, scope, finances, stakeholders, vendor relationships, project documentation, performance tracking, and reporting. Apply project management methodologies (Agile/Waterfall) and leverage AI platforms to increase efficiency.

Build and maintain internal platforms, automations, and integrations to scale IT operations. Own identity, access, lifecycle automation, endpoint trust, SaaS provisioning, and operational reporting. Develop scripts and services (Python, Bash), partner with Security and Engineering for secure AI, Zero Trust, HIPAA and SOC 2 compliance, and apply DevOps/SRE/ITIL practices for monitoring and incident response.

Serve as Product Owner for Oracle/Cerner clinical solutions, partnering with clinical stakeholders and technical teams to define requirements, manage backlogs, configure and validate clinical content, support enterprise deployment and standardization, and drive adoption, testing, and optimization across the product lifecycle.