Top C# Jobs in San Diego, CA

Senior .NET developer to deploy ASP.NET applications to Amazon Web Services, build real-time vessel tracking and reporting views, and work with C#, SQL Server, MVC, Windows Communication/Services, and firmware in an Agile environment. 6-month contract-to-hire based in San Diego.

The role involves maintaining lab automation equipment, supporting workflow in protein therapeutic discovery, and collaborating on automation-driven research workflows.

Design, build, and operate scalable AWS-based backend services and APIs for the Collectors Vault. Own architecture and delivery, improve performance and reliability, mentor engineers, and leverage modern AI tools to accelerate development and engineering velocity.

Lead backend and full-stack work on the Payments team, building multi-gateway integrations (Stripe, PayPal), payment APIs, and customer payment UIs. Ensure secure, compliant (PCI-DSS) payment flows, reliability, observability, and scalability across AWS/Kubernetes microservices. Partner cross-functionally to design architecture, implement settlement/reconciliation, and maintain high availability.

The Principal Software Engineer will design and oversee architecture for software systems, collaborate with teams, and ensure robust, secure solutions for debt solutions products.

Develop scientific software for AI-native drug discovery, building data pipelines, APIs, and lab automation integrations while collaborating with scientists.

Design, implement, and optimize gameplay mechanics and systems. Collaborate with designers, artists, and developers to troubleshoot and refine code, optimize performance across platforms, and maintain clean modular code while staying current with game technologies.

Design and develop software for automated laboratory workflows, build data pipelines, implement machine learning models, and integrate various systems to enhance biotherapeutics discovery.

Lead design, development, and modernization of a proprietary Loan Management System. Build and refactor full-stack features, improve scalability, reliability, CI/CD, and observability, troubleshoot production issues, and collaborate with Product, QA, DevOps, and engineering teams while mentoring peers and driving engineering best practices.

Design, develop, and maintain integrations, SharePoint Online sites, and AI-driven automation. Build data pipelines (SSIS/SSRS/SQL), Copilot Studio agents, and custom solutions (C#, .NET, PowerShell). Ensure secure Azure-hosted environments, troubleshoot integrations, and collaborate with stakeholders to deliver scalable workflows.

The Sr. Vision Software Engineer will design, test, and integrate machine vision solutions, develop computer vision algorithms, and troubleshoot production issues while collaborating with engineering teams.

Build, own, and operate cloud-native .NET services powering real-time trading, market data, and brokerage integrations. Ship features end-to-end, write tests, participate in on-call rotations, improve observability, and occasionally contribute to React/TypeScript frontend work.

Design and implement PostgreSQL internals and indexing strategies for large-scale document workloads. Extend query engine with BSON-aware operators and custom scan nodes, optimize index pruning, profile distributed system performance, collaborate with open-source communities, and lead design/code reviews.

Design and implement PostgreSQL internals, indexing, query engine extensions, and storage-layer features to support large-scale document workloads on Azure. Profile distributed systems, tune performance, collaborate with open-source communities, conduct design/code reviews, and drive cross-team alignment for mission-critical database features.

Design and implement PostgreSQL internals and indexing/query features for large-scale document workloads, extend query engine with BSON-aware operators and custom scan nodes, tune index pruning and storage, profile distributed systems for performance, collaborate with open-source DocumentDB/PostgreSQL communities, and participate in design/code reviews.

Design, configure, and develop custom solutions on Microsoft Power Platform and Dynamics 365. Implement full life-cycle D365 deployments, monitor batch jobs and integrations, build BI solutions (SSIS/SSAS/SSRS), and support Microsoft Portals. Work with clients, provide technical leadership, and maintain ERP and CRM integrations using tools like Scribe, Power Automate, C#, SQL, and .NET.

Design, architect, and implement cloud-first full-stack software using Java/C# and JavaScript frameworks. Provide technical leadership, mentor engineers, improve architecture and performance, promote CI and automated testing, and support customer implementation and cloud platform operations.

Lead design, development, and deployment of scalable, fault-tolerant cloud-native microservices. Own architecture, mentor engineers, run on-call rotations, triage production incidents, optimize performance, and collaborate with product and stakeholders to deliver full‑stack and mobile solutions.

Design, build, test, deploy, and maintain responsive web applications and back-end services for mortgage origination, servicing, sales, and operations. Create and optimize RESTful APIs, integrations, databases, and reusable UI components; ensure security, accessibility, performance, and CI/CD-driven delivery while collaborating with stakeholders and participating in Agile processes.

Lead and grow an engineering team that designs, builds, and operates hyperscale distributed systems and cloud-native platform services for Azure. Drive technical strategy, architecture, cross-team initiatives, operational excellence, and stakeholder collaboration to deliver scalable, reliable, secure, and observable infrastructure solutions.

Design, implement, and maintain custom test frameworks for Illumina's primary analysis software. Create and expand automated tests, troubleshoot CI/CD pipelines, investigate failures, collaborate with developers to diagnose root causes, and ensure tests are reproducible, documented, and maintainable as analysis capabilities evolve.

Design and develop native Sage Intacct payment integrations and AR/AP workflows, implement APIs/SDKs, ensure PCI-compliant secure architectures, troubleshoot integration issues, collaborate with product/support teams, produce documentation, and monitor/optimize integration performance.

Lead and grow a software engineering team to design, build, and operate high-performance, scalable, observable networking systems for Azure AI/HPC infrastructure. Drive architecture, reliability, testing, automation, and cross-team collaboration to support large-scale distributed training and inference workloads.

Lead architecture and design for Azure capacity infrastructure, leveraging AI/Copilot to evolve platforms and tools. Guide virtual teams, define requirements and design documents, drive releases, optimize and refactor code, monitor systems as DRI, and ensure products meet scalability, performance, security, and reliability goals.

Develop, enhance, test, deploy, and maintain Microsoft Power Platform solutions (Power Apps, Power Pages, Power Automate, Dataverse). Design data models and integrations using Azure services, REST APIs, and custom connectors. Support Agile delivery, testing, migrations, documentation, deployments, security, privacy, and Section 508 accessibility compliance.