Top Senior IT Jobs in Phoenix, AZ

Perform financial analyses for IT, develop Total Cost of Ownership and forecasting models, and recommend financial strategies. Support IT operations/governance, integrate financial checkpoints into governance, and apply Agile delivery principles to align services and outcomes.

Lead and continuously improve the global IT Compliance function for a CRO, ensuring IT governance, ISMS and ISO 27001 certification support, GxP computerised system compliance, audit readiness and vendor/third-party compliance oversight. Provide regulatory guidance, manage audit responses, run risk assessments, maintain compliance documentation, and drive remediation and continual improvement across IT and business stakeholders.

Manage operations and maintenance of Consumer Health S/4HANA ecosystems, including request and incident lifecycle, event management, application security, capacity and production transition, vendor escalations, and continuous service improvement to ensure rapid recovery and reliable service delivery.

Serve as Product Owner for Oracle/Cerner clinical solutions, partnering with stakeholders to define workflows, write user stories, manage backlogs, configure systems, support enterprise deployment and adoption, and provide SME through the product lifecycle. Requires risk mitigation, cross-team collaboration, and occasional travel.

Serve as strategic advisor to assess and optimize end-to-end hospital revenue cycle operations using Epic workflows. Lead performance improvement, analytics, change management, compliance, and operational initiatives to improve financial and patient financial experience.

Provide senior-level remote IT support and operations for a distributed workforce: troubleshoot macOS/Windows/Linux/mobile, manage onboarding/offboarding, administer identity (Rippling/Okta) and MDM, maintain asset inventory, build AI-driven automations (Console.com, Risotto, Unthread), support SOC 2/HIPAA/ISO compliance, write runbooks in Notion, and contribute to the IT roadmap while mentoring the team.

The Senior IT Program Manager leads program development and implementation, ensuring projects align with business needs and are delivered on time and budget. They manage stakeholder relationships and facilitate communication with senior leadership, oversee financial management, and develop risk management strategies.

Serve as first-line IT support for hardware, software, networking, and enterprise applications. Triage and resolve support tickets, manage onboarding/offboarding, administer Okta and endpoint management (Intune, Jamf), maintain device health and access controls, collaborate with Security and Engineering, document processes, and improve support workflows to ensure a secure, compliant, and user-friendly hybrid work environment.

The role involves designing and developing enterprise-grade software solutions, integrating AI tools, collaborating with teams, and maintaining documentation while enhancing productivity for Yahoo personnel.

The IT Systems Engineer III will improve Ophelia's IT systems through integration, automation, and security while managing IT projects, overseeing service providers, and ensuring compliance.

Provide administration, maintenance, development, and troubleshooting for Oracle IAM (OAM, OIG, OID, OIM) including provisioning, authentication, RBAC/ABAC controls, custom Java/REST integrations, BI Publisher reporting, and IAM continuous monitoring. Produce SOPs, coordinate with SMEs, and apply secure coding and audit practices to support production and non-production environments.

Design and guide secure, scalable enterprise and cloud architectures (DNS, Azure, AWS, on-prem). Lead cloud migrations, implement monitoring, integrate hybrid environments, present technical briefings, and mentor staff while ensuring security and performance for a mission-focused government client.

Lead Data QA for the Enterprise Data Warehouse: define QA strategy, design and execute source-to-target validations, CDC and ETL checks, data masking verification, build quality dashboards and automations, mentor QA analysts, manage defects and release readiness, and collaborate with Data Engineering, BI, Product, and stakeholders to ensure data is accurate, complete, and audit-ready.

Lead human-centered design and front-end engineering for the NIH Data Lakehouse: conduct user research and testing; create wireframes, prototypes, flows, and accessible interfaces; build scalable React/Next.js/TypeScript UI components; integrate with GraphQL and search services; contribute to design systems, component libraries, and platform-wide front-end best practices.

Senior IT leader partnering with Commercial leadership to define and deliver pharma commercial technology strategy, oversee Veeva and digital platforms, lead product launch technology readiness, manage vendors/agencies, ensure compliance and governance, and lead IT teams to deliver scalable, secure commercial applications and digital experiences.

The Lead IT Telecom Architect designs and optimizes Telecom and Contact Center architecture to meet business goals, ensuring security and performance. Responsibilities include strategy development, technology evaluation, system implementation oversight, and stakeholder collaboration.

Design, build, and operate AWS-native AI/ML systems: RAG pipelines, fine-tuned LLMs, and microservices. Implement IaC (Terraform), CI/CD, policy guardrails, and production deployments integrating Bedrock/SageMaker, LangChain, and telemetry for secure, scalable enterprise use.

Lead IT strategy and operations for a multi-site nonprofit: oversee MSP, infrastructure, networking, cloud, Microsoft 365, identity, cybersecurity, ITSM, AI readiness, budgets, vendor management, and disaster recovery to enable secure, scalable services and data-informed decisions.

Plan, conduct, and supervise complex IT audits of infrastructure, security, operating systems, and controls. Produce and review audit reports, advise on internal controls, lead audit tool development, supervise auditors, and communicate findings to stakeholders while supporting data and system confidentiality.

Design, implement, administer, and support operational IT systems for power generation. Lead technical solutions, manage Operations IT projects, develop procedures to meet reliability and regulatory standards, identify process improvements, support System Operators/Generation Dispatch/Power Marketing, apply SDLC and project methodologies, manage risks, and maintain documentation and stakeholder communication.

Lead medium-to-large IT infrastructure and cybersecurity projects from intake through transition. Manage governance, scope, schedule, budget, risks, dependencies, and stakeholder communications. Translate technical engineering and security work into executable plans, drive benefits realization, ensure operational readiness, and mentor other project managers.

Lead enterprise IT sourcing and software procurement for complex renewals and strategic sourcing initiatives. Drive savings, establish governance, create vendor strategies and KPIs, partner with IT and stakeholders, mentor procurement staff, and manage contract negotiations and renewals.

Design, modify, and program software for local, networked, cloud, or internet applications. Write code, test and debug, document installation and maintenance procedures, gather user requirements, implement enhancements, and perform related duties.

Lead and supervise global end-user support and client engineering for endpoint lifecycle management, device provisioning, imaging, software deployment, patching, compliance, and workplace technology. Drive service improvements, collaborate with cybersecurity and infrastructure teams, manage escalations, coach staff, coordinate rollouts, and maintain operational documentation and asset controls.

Lead and mentor the Infrastructure team and deliver the enterprise infrastructure roadmap. Design and maintain resilient on-prem and cloud (Azure) network and server environments, oversee capacity planning, monitoring, backup/recovery, disaster recovery, vendor management, and infrastructure automation. Support ERP/Sage X3 infrastructure, collaborate with InfoSec on vulnerability remediation and OT teams for manufacturing environments, and manage infrastructure projects and on-call escalations.