Top Data Science Jobs in Buffalo, NY

Develop and productionize machine learning models and predictive analytics using Python, Databricks, PySpark, SQL, and Delta Lake. Build scalable data science workflows, resolve healthcare data quality and entity-resolution issues, and apply Master Data Management practices. Partner with engineering, product, analytics, and business teams to deliver governed, HIPAA-compliant solutions. Perform exploratory analysis, feature engineering, model evaluation, deployment, documentation, and data lineage management for healthcare and member engagement initiatives.

Leads and mentors junior developers while designing, modifying, testing, and deploying data solutions in Palantir Foundry. Builds data models and reports from ERP and legacy systems, translates business requirements into technical capabilities, and supports IT modernization. Requires Python, PySpark, cloud architecture, CI/CD, database design, Army domain knowledge, and an active DoD Secret clearance.

Lead design and delivery of scalable ML systems across the full lifecycle for recommendations, demand forecasting, targeting, and personalization. Collaborate with engineers, product, and stakeholders to set architecture, metrics, and production best practices; mentor data scientists; lead experimentation and deploy/monitor models using cloud and MLOps tooling.

Develop and lead data science and machine learning initiatives, including exploratory analysis, predictive modeling, experimentation, recommendation systems, user classification, model monitoring, and production deployment. Partner with product, marketing, analytics, and engineering teams to convert user insights into automated services. Manage projects throughout their lifecycle, support strategic ML planning, and deliver solutions for personalization, cross-selling, and retargeting.

Consult as a fractional data scientist for hedge funds, private equity firms, and family offices. Lead data science initiatives: build infrastructure, develop and deploy models, create portfolio dashboards, monitor post-deployment performance, and partner with investment teams to turn data into actionable investment insights. Advise on vendor selection, data quality, technology stacks, KPIs, and governance.

Build end-to-end data science, machine learning, forecasting, time-series, and AI solutions for supply chain and manufacturing operations. Develop analytical datasets, ETL/ELT workflows, dashboards, APIs, and production models using Python, SQL, cloud platforms, and modern data technologies. Partner with business and technical stakeholders to improve inventory, demand forecasting, delivery, production planning, cost, and operational efficiency. The role owns solutions from problem definition through deployment, monitoring, adoption, and continuous improvement.

Builds a talent network of experienced data scientists for potential future AI evaluation projects. Responsibilities may include creating grading criteria, evaluating AI-generated or human-produced data science work, writing evidence-based justifications, applying consistent judgment, and incorporating reviewer feedback. Candidates should have professional data science experience, strong Python and SQL skills, expertise in statistical modeling, machine learning, experimentation, causal inference, and excellent technical communication.

Lead end-to-end pricing experimentation and strategy for consumer and business products. Design and analyze A/B tests, build pricing models and production-grade data pipelines, partner cross-functionally, and present actionable recommendations to senior leadership.

Develop statistical and machine learning models for clinical trial enrollment, patient matching, forecasting, and trial management. Monitor model performance and bias, build scalable data pipelines using AWS services and dbt, and ensure compliance with HIPAA, GDPR, and privacy standards. Collaborate with ML engineering, product, and clinical research stakeholders to integrate models into practical healthcare solutions.

Drive product-led growth through rigorous analysis of onboarding, activation, adoption, retention, expansion, and monetization. Partner with Product, Engineering, Design, Marketing, and Sales to design experiments, analyze funnels and cohorts, identify behavioral signals, build metrics and dashboards, improve instrumentation, and translate uncertain or incomplete data into actionable product recommendations.

Lead product and program analytics for Microsoft skilling experiences: design learner journey/funnel analyses, define success metrics, run experiments and causal analyses, build proficiency/competency models, shape telemetry and scalable reporting, recommend content and curriculum improvements, and mentor other data scientists to drive product decisions and learning outcomes.

Build and deploy mechanistic, hybrid, and data-driven models for pharmaceutical CMC processes, including drug substance, drug product, packaging, labeling, technology transfer, and manufacturing. Integrate process and experimental data into FAIR data products, analytics, dashboards, and AI-enabled tools. Partner with technical teams and CDMOs to support process understanding, forecasting, risk assessment, regulatory filings, and technology-transfer decisions while owning the digital roadmap and mentoring colleagues.

Develop and deploy machine learning models for manufacturing use cases including predictive quality, machine failure prediction, and time-series pattern discovery. Work directly with customers to scope problems, validate solutions in live deployments, and translate successful analyses into product features. Collaborate with engineering, product, and customer success teams while applying statistics, optimization, generative AI, and agentic AI to deliver end-to-end solutions.

Lead end-to-end data science projects: acquire and prepare messy datasets, develop and evaluate models tied to business outcomes, operationalize models at scale, run experiments, drive ethics/privacy, partner with customers and teams, and coach cross-disciplinary colleagues.

Lead data science engagements with customers to acquire, clean, analyze, and model data; develop scalable operational models and evaluation methods; coach engineers on best practices; drive solution strategy, ethics, and industry thought leadership; write extensible code and collaborate across teams to deliver cloud-based AI solutions.

The Senior Data Scientist develops quantitative models for financial crime compliance, performs data analysis, and collaborates across teams to enhance model performance.

Designs, develops, evaluates, and deploys AI and data-driven solutions using machine learning, deep learning, NLP, LLMs, intelligent agents, prompt engineering, and RAG. Builds scalable data pipelines, experiments with models, deploys AI services through APIs and cloud infrastructure, and monitors system reliability and performance. Collaborates with engineering, product, and customer-facing teams to translate business needs into production-ready solutions while addressing risks and continuously improving AI capabilities.

Own revenue-focused data science from opportunity sizing through production ML. Investigate and measure product changes, build and operate batch and online ML systems for personalization, experimentation, and automation, and partner cross-functionally to integrate models into user-facing products. Establish monitoring, lineage, reproducibility, and security practices; improve data pipelines; mentor data scientists; and define ML development best practices while using AI tools to accelerate delivery.

Design and deploy optimization and machine learning models for allocating scarce parts and resources across competing programs. Responsibilities include formulating MILP and constraint optimization models, forecasting demand and supply risk, building data pipelines, validating outputs, communicating tradeoffs to stakeholders, mentoring junior data scientists, and partnering with software engineers to productionize scalable services.

Lead end-to-end AI/ML initiatives that improve student retention, engagement, enrollment, and re-engagement. Build and deploy predictive models, next-best-action logic, and production MLOps workflows using Databricks, MLflow, dbt, and Dagster. Own experimentation, monitoring, performance measurement, cross-functional implementation, vendor coordination, and executive communication. Mentor teammates and drive measurable outcomes across Product, Engineering, CX, and university partners.

Leads the data science platform and machine learning strategy, building data marts, predictive models, MLOps infrastructure, and analytics capabilities. Analyzes healthcare claims, clinical, workflow, and operational data to risk-stratify patients, assess clinical program impact, support dashboards, and improve patient and provider engagement. Collaborates with clinical, operations, finance, product, executive, and technology teams while serving as a trusted analytics expert for a business workstream.

Lead product-focused data science and machine learning initiatives, including exploratory analysis, production model development, evaluation frameworks, generative AI, graph-based machine learning, recommendation systems, and personalization. Collaborate with engineering, product, and business teams to deliver high-impact solutions, influence strategy, and communicate insights to technical and non-technical stakeholders. The hybrid role requires four days per week in the Greater Boston area.

Lead design and evolution of large-scale nodal power market models. Define mathematical approaches, develop optimization/forecasting methodologies (MILP, SCUC/SCED), collaborate with engineers to productionize models, work with product and customers to translate market problems into software, mentor data scientists, and guide long-term product strategy.

Own and deliver production machine learning workstreams for utility bill extraction, forecasting, and audit/anomaly detection. Build and evaluate models, establish technical approaches for ambiguous problems, write production-grade Python, and partner with engineering on integration and monitoring. The role also involves applying LLMs and agentic workflows, automating team processes, prioritizing investments, and communicating model behavior and recommendations to technical and nontechnical stakeholders.

Lead end-to-end AI/ML initiatives to improve student retention, engagement, and enrollment. Architect and operate data pipelines, feature stores, and production ML systems; deploy, monitor, and automate models; run experimentation programing and measure business outcomes. Mentor team members and set technical standards across Product, Engineering, and CX.