Top IT Jobs in Buffalo, NY

Lead IT SOX controls testing for ITGCs (access, change, operations) across blockchain-native and enterprise systems. Build testing programs, validate remediation, perform root-cause analysis, report to Audit Committee, and collaborate with Engineering, Security, and external auditors to ensure SOX compliance and scalable audit processes.

The role involves leading business development for IT solutions in federal contracting, leveraging relationships to identify opportunities and influence procurement strategies, while collaborating with various teams to drive success.

The Manager of IT Engineering leads IT operations including identity management, SaaS, endpoint management, and internal tooling. This role ensures service quality and scalability for a remote workforce.

Support and enforce NIST/CMMC-aligned security controls; monitor SIEM/EDR and perform incident triage and response; manage Windows/AD environments; conduct vulnerability scanning and remediation; protect and classify FCI/CUI; support audits and control validation; maintain compliance documentation; collaborate with IT and business teams and communicate security risks to technical and non-technical stakeholders.

Manage internal IT infrastructure and developer operations while leading frontend web work. Run developer standups, own sprint planning in ClickUp, triage requests, perform hands-on frontend fixes (HTML/CSS/JS), manage AWS resources, administer Google Workspace and Okta SSO, oversee VPN and endpoint security, and coordinate QA and deployments across web properties.

Provide hands-on end-user IT support: troubleshoot OS/software, respond to tickets, apply patches, manage user accounts via Okta, configure MDM-managed mobile devices, and support Slack and Google Workspace integrations.

Lead research and advisory work on enterprise IT and AI strategy; produce thought leadership and actionable insights for CIOs and C-suite; advise clients, present at events, support sales, mentor analysts, and drive research agenda and process improvements.

The IT Manager, Product Owner - Finance drives financial process transformations, prioritizes product backlogs, and manages stakeholder relationships to ensure high-quality delivery of financial systems solutions.

Develop and maintain Digital Workplace tools, working closely with teams, performing testing, debugging, and technical research. Requires web development experience and familiarity with modern software architectures.

The IT Project Manager will oversee project planning, implementation, and client interactions while ensuring compliance with federal and state regulations in the public sector.

The IT Project Manager will lead public sector ERP migration projects, ensuring high-quality deliverables and strategic alignment while collaborating with various stakeholders.

Design, deploy, and maintain a secure cloud-native Enterprise Data Warehouse using DevSecOps practices. Build and operate automated CI/CD pipelines, IaC, containerized workloads, security/compliance integrations, continuous monitoring, vulnerability management, and change-control. Document processes, provide training, coordinate standards across stakeholders, and produce metrics to drive improvement.

Design, modernize, and optimize hybrid cloud and legacy relational databases (Informix, DB2, MySQL, Oracle, PostgreSQL). Collaborate with engineers and security teams to implement migrations, performance tuning, data modeling, SQL/PLSQL development, automation, and DevSecOps practices to support cloud adoption and mission-critical operations.

Lead delivery and oversight of internal and client projects, ensuring on-time, on-budget completion. Manage resources, risks, scope, finances, stakeholders, vendor relationships, project documentation, performance tracking, and reporting. Apply project management methodologies (Agile/Waterfall) and leverage AI platforms to increase efficiency.

Build and maintain internal platforms, automations, and integrations to scale IT operations. Own identity, access, lifecycle automation, endpoint trust, SaaS provisioning, and operational reporting. Develop scripts and services (Python, Bash), partner with Security and Engineering for secure AI, Zero Trust, HIPAA and SOC 2 compliance, and apply DevOps/SRE/ITIL practices for monitoring and incident response.

Serve as Product Owner for Oracle/Cerner clinical solutions, partnering with clinical stakeholders and technical teams to define requirements, manage backlogs, configure and validate clinical content, support enterprise deployment and standardization, and drive adoption, testing, and optimization across the product lifecycle.

Provide onboard IT systems support, maintenance, monitoring, backups, inventory, hardware shipping/receiving, equipment repairs, user support and training, and escalate issues to the IT Officer while maintaining security and service standards.

Lead and execute IT audit engagements across APAC, evaluating IT infrastructure, cybersecurity, applications, and controls. Use data analytics to design and perform data-driven audit procedures, validate remediation, prepare audit reports and working papers, support continuous auditing and automation, and collaborate with regional/global audit teams and governance forums.

The Project & IT Budget Analyst manages project coordination and IT budget oversight, supporting strategic initiatives and ensuring financial accuracy.

Lead CPIC activities for OCSE: prepare IT portfolio submissions, ensure compliance with OMB/HHS/ACF reporting, support EVM and performance management, coordinate stakeholders, develop templates/processes, produce analyses and executive briefings, and support budget and risk reporting.

Define and execute enterprise strategy for data, analytics, AI, automation, and innovation. Build data governance, architecture, engineering, BI, and AI adoption (including Generative and Agentic AI). Identify high-value use cases, scale emerging technologies, partner with IT functions, lead high-performing teams, advise executives and board-level stakeholders, and ensure security, privacy, governance, and responsible AI compliance.

The Senior IT Project Manager oversees the delivery of technology and business transformation projects, supports PMO standards, manages project risks, and mentors junior managers.

The Senior IT Risk and Compliance Analyst manages vendor risk, ensures compliance with regulations, documents controls, and supports risk mitigation efforts across IT teams.

The IT Systems Engineer will manage IT operations, support M&A integrations, and optimize Microsoft cloud systems, ensuring reliability and security.

Lead global IT strategy and operations for a life‑sciences CRO: oversee cloud and infrastructure, cybersecurity and compliance (GxP/21 CFR/GDPR), enterprise applications and data strategy, digital transformation, vendor and budget management, and build a global IT organization to enable clinical research, data science, and product delivery.