Top St. Louis, MO Startups (10,000+)

We’ve built the industry’s highest ceiling and most secure Action & Agent building platform for sticky, custom AI workflows. Use cases span countless domains, including: KYC, anti-money laundering, healthcare regulation, climate standards setting, cybersecurity, sales, people, IT, and customer support.

TigerConnect is healthcare’s most widely adopted communication platform – uniquely modernizing care collaboration among doctors, nurses, care teams, and patients. TigerConnect is the only solution that combines a consumer-like user experience for both clinical and patient communication with serious security, privacy, and clinical workflow requirements that today’s healthcare organizations demand. TigerConnect accelerates productivity, reduces costs, and improves patient outcomes. Trusted...

Akeneo is the product experience (PX) company and global leader in Product Information Management (PIM). Akeneo empowers business leaders with software, education, and an engaged community all focused on the practice of product experience management. Leading brands, manufacturers, distributors, and retailers, including Chico’s, CarParts.com, TaylorMade Golf, Rail Europe, Kering, and more trust Akeneo to scale their commerce initiatives. Using Akeneo’s...

Founded by The Allstate Corporation in 2016, Arity is a mobility data and analytics company focused on improving transportation. We collect and analyze trillions of miles of driving data, using predictive analytics to build solutions with a single goal in mind: to make transportation smarter, safer and more useful for everyone.

Agentio enables marketers to buy creator led ads as easily and scalably as Meta or Google ads—automating sourcing, pricing, contracting, delivery, and measurement—so work that took months now happens in minutes. We’re on a mission to transform a $600B digital ad ecosystem by shifting digital ad spend into the hands of creators. That means better outcomes for marketers and enabling creators...

At Braze, we believe in the passion of our people. We seek to ignite that passion by setting high standards, championing teamwork, and creating work-life harmony. We thrive when people add their unique perspectives to our ever-growing teams—and we strive to empower you to make an impact that fuels both you, and our business.

At Affirm, we help people say yes to the things that matter with flexible, transparent ways to pay over time. No hidden fees, no compound interest, and no fine print—just a smarter way to spend.

We’re a fast-growing technology company transforming fixed income trading. With a proven track record of innovation, we’ve become one of the three largest electronic trading platforms in the U.S. Each month, more than 1,400 traders from nearly 1,000 buy- and sell-side institutions transact on Trumid, a testament to the scale, connectivity, and engagement of our expanding client network. We combine...

Ethic partners with advisors and institutions to deliver personalized, values-aligned, and tax-smart investing. Our technology powers sophisticated investment solutions through a simple and engaging client experience. Headquartered in New York City, our growing team brings a diverse set of backgrounds and experiences. We’re a financial technology company building the investment management platform of the future.

We are an omnichannel customer acquisition platform with offices throughout the US, Canada and Europe. System1 builds desktop and mobile apps, search engines, and online publications that empower consumers with information while respecting their privacy. We also operate brands that include CouponFollow, Startpage and MapQuest. System1 is a champion of AI technology, investing in the first legal AI called Vinny...

Squarespace is a design-driven platform helping entrepreneurs build brands and businesses online. We empower millions of customers in more than 200 countries and territories with all the tools they need to create an online presence, build an audience, monetize, and scale their business. At Squarespace, we celebrate creative possibility. With a culture rooted in curiosity, Squarespace aims to provide its employees...

Navan is the leading all-in-one business travel and expense management solution that makes travel easy for frequent travelers. From finding flights and hotels, to automating expense reconciliation, with 24/7 support along the way, Navan delivers an intuitive experience travelers love and finance teams rely on. See how Navan customers benefit and learn more at navan.com.

Sonatus is a global vehicle software company enabling AI-powered, software-defined vehicles through its platform, which is deployed in over 5 million cars, helping automakers continuously improve cost, performance, reliability, and user experience.

ePayPolicy is a fast-growing tech company in the heart of Austin. Our payment processor enables insurance professionals to accept electronic payments, & our tech is changing the industry. We are the BEST at what we do, and always encourage ideas & creativity. We're just a fun bunch excited to push the envelope each day! #YouCanWorkWithUs #LetsGo

Domino Data Lab powers model-driven businesses with its leading Enterprise AI platform trusted by over 20% of the Fortune 100. Domino accelerates the development and deployment of data science work while increasing collaboration and governance. With Domino, enterprises worldwide can develop better medicines, grow more productive crops, build better cars, and much more. Founded in 2013, Domino is backed by...

Technology has revolutionized the operations of public markets. The improvement in capabilities has raised investor expectations and regulatory demands, but the private markets can’t keep up. Global private markets manage $15 trillion dollars. Despite its importance in the global economy, investment managers still run their operations on a patchwork of legacy software providers and manual spreadsheets, creating massive inefficiencies and...

Hiya is trusted by global businesses, carriers, and consumers to enable secure, engaging connections and stop unwanted calls. Hiya is pioneering the next generation of AI-powered voice intelligence with real-time analysis and an AI assistant to enhance voice protection, productivity, and call performance. Hiya connects businesses with their customers, helps carriers secure their networks, and protects people from spam and...

Comcast Advertising is driving the TV advertising industry forward, from delivering ads to linear and digital audiences to pioneering the tech that makes it possible. We help brands connect with their audiences on every screen using advanced data. Just as important as our work is our inclusive and supportive culture, which has earned us recognition as one of the top...

The power it has to uplift and bring people, Guided by our purpose - Celebrating real connections through delicious, planet-friendly food - we believe that working together with our teams, business and community partners will bring sustainable growth and positive change - today, tomorrow and for generations to come. As a privately owned family company with over 60 years of...

Greenlight Guru is the only quality management software platform designed specifically for medical device companies. Our software drives medical device companies to build higher-quality devices more efficiently. This impacts millions worldwide.