Top Project Manager Jobs in St. Louis, MO

Manage biomarker operational work for clinical trials, oversee junior project managers, and collaborate with internal and external stakeholders to ensure project success.

Lead as a technical operator between product, engineering, design, and leadership to remove blockers, accelerate delivery, and compress feedback loops. Drive rapid prototyping-to-production cycles, introduce AI tooling and lightweight processes, directly contribute to delivery, surface risks and dependencies, and scale team workflows so the product organization ships higher-quality features faster.

The Senior Operational Project Manager coordinates delivery across multiple departments, manages client engagements, oversees resource allocation, and ensures project timelines are met within a fast-paced marketing agency environment.

The Technical Project Manager will oversee R&D Cloud initiatives, manage project scope, timeline, and budget, and ensure cross-functional collaboration to deliver innovative solutions.

Lead and oversee consulting, design, or construction management for large, complex life-sciences and food & beverage projects. Manage client relationships, large teams, subcontractors, project delivery, and ensure successful execution under ONEsolution methodology.

Lead and improve project development operations for industrial projects from concept through readiness for design and construction. Develop processes, train teams, integrate third-party engineers/vendors, manage contract and scope changes, conduct performance reviews, coordinate resources in a matrix organization, support client engagement, and ensure consistent execution of project delivery and best practices.

Lead planning, execution, and delivery of enterprise technology projects. Manage scope, timelines, budgets, resources, risks, vendors, and stakeholder communications across Agile, Scrum, and Waterfall environments. Oversee software development, technology implementations, cloud transformation, application modernization, and other enterprise initiatives while coordinating cross-functional teams and multiple concurrent priorities.

Lead technical project delivery and roadmap evolution for content authoring platforms. Translate business goals into technical requirements, guide design discussions, manage integrations and data interoperability, and coordinate with vendors and education agencies. Investigate production issues using SQL Server and log analysis, oversee deployments with DevOps and SRE teams, support QA, mitigate technical risks, and maintain technical documentation.

Lead and coordinate client-facing technical implementations for web, webapp, and mobile projects. Manage cross-functional teams, schedules, finances, documentation, QA/UAT, and project management tools to ensure scope, sprints, and deployments stay on track while keeping clients informed.

Lead end-to-end project planning and delivery for multiple concurrent events, managing logistics, vendors, budgets, on-site execution, and post-event wrap. Coordinate cross-functional dependencies, enable junior PMs, build delivery systems, surface risks, and make real-time resourcing decisions. Travel up to 40%.

Manage data management and analytics projects, utilizing agile practices. Coordinate with cross-functional teams to ensure successful delivery and mitigate risks.

Lead client-facing data and AI delivery teams to deliver projects on time, on budget, and within scope. Create roadmaps, manage schedules, budgets, risks, and communications; mentor other Project Managers; collaborate with technical leads and clients; support scoping, estimation, and business development. Ensure quality, guide stakeholder alignment, and drive successful outcomes across multiple simultaneous engagements.

Lead and deliver multiple customer-facing SaaS implementation projects from initiation through closure. Manage plans, budgets, schedules, risks, change control, cross-functional teams, and stakeholder communications. Act as primary customer liaison, track outcomes and ROI, resolve escalations, maintain project documentation and SOPs, and drive process improvements to ensure successful adoption and business outcomes.

Lead and deliver complex IT programs through full lifecycle: plan, execute, and close projects on time and budget. Manage budgets, vendors, cross-functional teams, stakeholders, and program reporting. Ensure quality, safety, customer satisfaction, and adherence to SDLC and PM best practices.

Lead end-to-end delivery of complex payments projects, managing plans, timelines, risks, and governance. Coordinate Product, Engineering, QA, DevOps, and Operations; manage integrations, transaction flows, and high-volume processing platforms. Track metrics, ensure security/compliance, facilitate delivery ceremonies, and drive operational readiness and stabilization.

Lead and deliver multiple SOW-based IT projects for MoDOT, manage schedules, RAID logs, testing gates, reporting, onboarding, transition activities, and ensure compliance with ADA/Section 508 and client acceptance processes.

Lead end-to-end delivery of CX and contact center projects: manage schedule, scope, risks, resources, budgets, and client/stakeholder relationships. Document requirements, run JAD sessions, ensure quality, profitability, and clear communication across teams and partners.

Lead development and delivery of Sage Intacct and business software solutions. Manage multiple client engagements, supervise project teams, ensure quality assurance, drive operations improvements, and grow consulting services regionally.

Lead end-to-end New Product Introduction programs, create and maintain integrated project plans, drive cross-functional alignment, manage risks and launch readiness, prepare executive reporting, and improve PM processes and governance to deliver products to commercialization.

The Project Lead will oversee and develop the business software consulting practice, manage projects, and enhance software delivery capabilities.

Lead and deliver large-scale Dynamics 365 ERP/CRM implementations (3–16 months) managing scope, schedule, budget, risks, and cross-functional teams. Communicate status to executives, coordinate resources and financials, and apply PMI and company delivery standards. May support sales, marketing, and administrative tasks.

Manage technology projects from $100,000 to $3,000,000+, overseeing software development, implementing project management best practices, and ensuring stakeholder communication. Provide team support and lead conflict resolution efforts while maintaining project accountability.

Lead high-complexity, multi-workstream software implementations for tier-one banks; own end-to-end delivery, stakeholder escalation, risk/compliance management, SOWs, UAT, and mentor project managers while driving client satisfaction and business growth.

Manage settlement fund distribution tasks: verify documentation and payment details, liaise between Project Management, Claims, Disbursements, Data, and Finance, track payment statuses, prepare readiness reports, maintain audit-ready records, and ensure compliance and high-quality deliverables.

The Project Program Manager will lead multiple AI-related projects, ensuring timely delivery and high standards while managing client communications and team accountability.