Top Senior Software Engineer Jobs in St. Louis, MO

Build and maintain developer-facing tools and APIs for MongoDB Atlas and Compass. Work full-stack on customer-facing UIs and backend services, design scalable, highly available web applications, collaborate cross-functionally, troubleshoot distributed systems, and improve performance and developer experience.

Design, build, deploy, and operate scalable backend platform services and shared libraries. Contribute to architecture, reliability, developer experience, continuous delivery, monitoring, alerting, and incident response. Investigate production issues, implement lasting fixes, participate in technical reviews, mentor engineers, and collaborate cross-functionally to deliver business value. The role also encourages thoughtful use of AI tools to improve productivity.

Leads end-to-end design, development, quality, and integration of complex software solutions and cloud services. Provides technical leadership for enterprise-wide projects, manages engineering processes, risks, dependencies, and delivery priorities, and writes code across the software ecosystem. Collaborates with multidisciplinary teams to deliver measurable, user-centric technology solutions, primarily supporting healthcare caregivers.

Lead full-stack software development across frontend and backend systems, delivering user-facing healthcare features from concept through iteration. Design APIs and application architecture, write technical specifications, improve testing and CI practices, collaborate with product, AI/ML, clinical, and UX teams, and guide cross-team technical decisions. The role involves React, Python, cloud infrastructure, databases, asynchronous workflows, and healthcare data technologies.

Build and evolve scalable systems that capture, ingest, and process real-time and recorded audio/video streams from telephony and meeting platforms. Design distributed media pipelines optimized for reliability, performance, and low latency; provide technical leadership and mentorship; solve complex systems problems; implement testing and quality practices; contribute to architecture and code reviews; and maintain security and compliance standards.

Build and ship product features incorporating machine intelligence and large language models. Architect scalable AI-powered functionality, conversational agent experiences, data pipelines, and third-party integrations. Collaborate with subject-matter experts and designers, make pragmatic technical decisions, and mentor teammates on data and AI practices. The role requires hands-on server-side web development, flexible scripting skills, strong system design judgment, and experience delivering AI-enabled products in a startup environment.

Own and lead Coinbase’s developer infrastructure platforms, including CI, build systems, and deployment orchestration. Set technical direction for complex cross-team initiatives, improve build and deployment performance, manage reliability and observability, and drive platform migrations and adoption. Partner with engineering leaders, operate production systems, mentor engineers, and deliver scalable tools used across the organization.

Owns delivery of backend money movement and card ledger systems, leading engineers through complex problems and ambiguity. Collaborates with product, design, analytics, and engineering stakeholders; defines scalable technical solutions; supports system availability, monitoring, on-call operations, code quality, and engineering standards. The role also includes mentoring and developing team talent while building highly available distributed systems for Affirm’s financial products.

Own and evolve Thrive Global’s enterprise identity platform, including sign-up, authentication, authorization, user identity management, and integrations with enterprise identity providers. Independently deliver complex projects, partner with Product and stakeholders, maintain reliability, participate in on-call and incident response, and ensure secure, scalable systems using modern identity protocols and credential-management practices.

Lead the architecture, development, and evolution of Keeper Commander, including Python and .NET SDKs, CLI tooling, APIs, and developer automation. Remain hands-on with coding, debugging, architecture, integrations, security, testing, and release engineering while mentoring a small team. Partner with Product, QA, and Security teams, support the open-source ecosystem, improve developer experience, and guide technical strategy for enterprise and DevOps integrations.

Lead the technical vision and architecture for scalable, secure, high-performance distributed systems. Provide engineering leadership, mentorship, and architectural guidance while driving reliability, automation, CI/CD, security, performance optimization, and technical strategy. Investigate emerging technologies, oversee complex problem-solving, establish engineering standards, and collaborate with product and business stakeholders to align technology roadmaps with organizational goals.

Define the technical vision and multi-quarter strategy for Coinbase’s FinHub financial infrastructure. Architect scalable ledger and money-movement primitives across fiat and crypto, ensuring double-entry accounting, idempotency, reconciliation, auditability, reliability, and safe failure recovery. Lead complex cross-team architectural initiatives, collaborate with finance, risk, compliance, and operations stakeholders, and mentor senior engineers while improving system design and operational excellence.

Build and scale accounting software synchronization solutions connecting BILL’s payment network with third-party accounting platforms. Lead end-to-end software design and delivery, develop scalable AWS microservices, improve platform performance, guide testing and CI/CD practices, resolve customer problems, mentor engineers, and use generative AI to accelerate development.

Build and maintain Curai’s marketing platform, including web features, APIs, data flows, event tracking, attribution measurement, SQL models, dashboards, and ClickHouse-backed marketing analytics. The role partners with marketing to scope engineering projects, improves site performance and conversion, investigates data quality issues, reviews code, strengthens testing and monitoring, and makes technical decisions across the engineering team.

Senior Software Engineer responsible for shaping and delivering a new fundraising product from discovery through production. The role involves full-stack development, architecture, prototyping, customer collaboration, production troubleshooting, reliability improvements, and mentoring. The engineer will work autonomously in an early-stage business unit, use customer feedback and data to guide decisions, and contribute across interfaces, backend services, integrations, infrastructure, and AI-enabled workflows.

Develop and maintain scalable Python/Django backend features for Cyware’s Cyber Fusion platform across commercial and AWS GovCloud environments. Design microservices, REST APIs, AI and RAG integrations, multi-tenant architectures, and secure identity systems. Ensure FedRAMP/GovRAMP compliance through secure coding, audit logging, RBAC, encryption, testing, and continuous monitoring. Collaborate with DevOps, GRC, Security, and engineering teams on CI/CD, code reviews, production support, and platform improvements.

The Senior Software Engineer designs and develops software applications, optimizes APIs and databases, collaborates with teams, and ensures code quality through various testing practices.

Define architecture and metrics for autonomous driving evaluation, lead cross-functional integration across autonomy and simulation teams, develop statistical and machine learning methods, analyze large-scale time-series data, manage evaluation KPIs and release gates, and communicate safety and readiness insights through dashboards and stakeholder presentations.

Design, build, and own scalable multi-tenant SaaS applications across frontend, backend, and data layers. Improve system architecture, performance, reliability, and testing practices. Integrate AI-assisted tools, mentor engineers, conduct code reviews, and collaborate with Product and Design to deliver intuitive, production-grade software.

Build and own full-stack features for a global peer-to-peer learning platform. Responsibilities include defining problems with users and stakeholders, developing prototypes and experiments, writing maintainable code, coordinating contributions, deploying products, and improving existing systems. The engineer will also participate in code reviews, pair programming, product ideation, and technical decisions balancing speed, quality, safety, and user experience.

Designs, develops, and leads scalable healthcare software solutions involving transaction processing, interoperability standards, integrations, and data platforms. Provides hands-on engineering, architectural leadership, quality ownership, risk management, technical mentorship, and cross-functional collaboration. The role requires building high-performance cloud-based SaaS solutions using microservices and serverless architectures, while guiding engineering strategy and ensuring secure, reliable delivery.

Lead development of Device OS platform infrastructure connecting industrial machines and applications to Apkudo. Own integration services, APIs, software and model deployment, staged rollouts, rollback, fleet monitoring, telemetry, diagnostics, and operator-facing control surfaces. Partner with robotics, AI, design, and operations teams to create reliable interfaces and deployment workflows for heterogeneous distributed devices.

Build and own Android growth and monetization experiments across subscriptions, advertising, purchases, and upgrade flows. Partner with product, design, data science, and analytics to instrument experiments, evaluate results, and ship reliable experiences at consumer scale. Use AI-native workflows for specification, coding, testing, and review; improve mobile engineering practices; contribute to architecture and code reviews; participate in on-call; and mentor engineers.

Develop and ship features for mobile games across Unity/C# clients and Go backend services. Collaborate with Product, Design, and Art, troubleshoot live-product issues, improve code quality, maintain build and content pipelines, conduct testing and code reviews, support releases, and investigate regressions. The role requires ownership from implementation through production with limited supervision.

Build and scale reliable software systems supporting donor platforms, cash payments, and rapid-response programs. Own features end to end from architecture through deployment and monitoring, improve CI/CD and testing, troubleshoot production issues, and collaborate with product, operations, and data teams. The role also contributes to technical roadmaps and sustainable engineering practices in a mission-driven, fully remote organization.