Top Senior Software Engineer Jobs in St. Louis, MO

Reposted 25 Days AgoSaved
Remote
St. Louis, MO
120K-290K Annually
Senior level
120K-290K Annually
Senior level
Software • Database
Design and build the control plane for Postgres clusters, ensure data protection, automate database operations, and collaborate with customers to enhance the platform.
Top Skills: AWSAzureGCPGoInfrastructure-As-CodeKubernetesPostgresPythonRubyRustZig
Reposted 25 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Edtech • Fintech • Information Technology • Software
The Senior Software Engineer will lead projects, architect solutions, mentor junior staff, and work full stack on platform development.
Top Skills: AWSDjangoHerokuJavaScriptMySQLNode.jsPostgresPyramidPythonRuby on RailsReactRubySqliteVue
Reposted 25 Days AgoSaved
Remote
St. Louis, MO
133K-197K Annually
Senior level
133K-197K Annually
Senior level
Database • Analytics
As a Senior Full-Stack Engineer, design and build scalable UI systems, own features end-to-end, collaborate on API design, and ensure production quality.
Top Skills: CSSGoGraphQLHTMLJavaScriptNode.jsReactRestTerraformTypescript
Reposted 25 Days AgoSaved
Remote
St. Louis, MO
176K-210K Annually
Senior level
176K-210K Annually
Senior level
Artificial Intelligence • Fintech • Software • Financial Services
The Growth Engineer will build and manage systems for GTM data, revenue automation, and personalization, impacting customer acquisition and revenue growth through scalable engineering solutions.
Top Skills: AirbyteClayHubspotJavaScriptPythonSalesforceSegment
Reposted 25 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Gaming • Software
As a Senior Frontend Software Engineer, you'll develop user-facing features using React and TypeScript, ensuring performance and cross-device compatibility while collaborating with teams to maintain a component library.
Top Skills: NextjsReactTypescript
Reposted 25 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Gaming • Software
As a Senior Mobile Engineer, you will develop high-performance mobile features using React Native and TypeScript, collaborating closely with designers and engineers to enhance user experiences.
Top Skills: Next.JsReact NativeTypescript
Reposted 25 Days AgoSaved
Remote
St. Louis, MO
150K-250K Annually
Senior level
150K-250K Annually
Senior level
Hardware • Information Technology • Software
The Senior Software Engineer will develop high-performance software for executing open-source LLMs on custom hardware, focusing on optimizations and efficient libraries primarily in C++.
Top Skills: Avx-512C++ClangFpgaGccHpcLlvmMlSimdSse
Reposted 25 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Artificial Intelligence • Information Technology • Consulting
The Senior HPC Cluster Engineer will optimize GPU clusters, troubleshoot InfiniBand networks, integrate new hardware, enhance automation systems, and manage GPU devices in HPC environments.
Top Skills: C/C++GoGpuInfinibandKubernetesKvmLinuxMpiNcclPythonPyTorchQemuRdmaRoceTensorFlow
Reposted 25 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Artificial Intelligence • Information Technology • Machine Learning • Software • Analytics • Consulting • Financial Services
Develop, test, and maintain a complex distributed processing application using Python and Java. Collaborate with product owners, data coaches, analysts, DBAs, and Agile teams to meet backend/frontend requirements. Work with distributed workloads (Spark/Hadoop), SQL/Snowflake, AWS, shell scripting, and job scheduling/process automation. Support delivery under Agile/SAFe practices and ensure alignment with program standards.
Top Skills: AWSBash/Shell ScriptingDroolsHadoopJavaLinux (Cli)OdmPythonSnowflakeSparkSQLVs Code
Reposted 25 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Software
The Software Engineer will manage data collection, optimize cloud infrastructure for data ingestion, and collaborate with AI researchers to enhance datasets for model training.
Top Skills: BashDockerGCPPythonTerraform
Reposted 25 Days AgoSaved
Remote
St. Louis, MO
175K-200K Annually
Senior level
175K-200K Annually
Senior level
Fintech • Software • Financial Services
The Senior Full Stack Software Engineer will design and develop software solutions, collaborate on product ideation, and improve tooling. They'll work autonomously to build an exceptional product in the fintech space.
Top Skills: FlaskNode.jsRuby on RailsReact
Reposted 25 Days AgoSaved
Remote
St. Louis, MO
125K-145K Annually
Senior level
125K-145K Annually
Senior level
Information Technology • Software • Automation
Design, develop, implement, test, and support high-quality internal software and customer-facing products. Enhance existing products and design APIs that integrate systems. Ensure security measures and perform code testing and reviews.
Top Skills: Asp.Net CoreAWSAzureC#DockerGitGCPKubernetesMongoDBRestful ApisWpf
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Reposted 25 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Healthtech • Internet of Things • Hospitality • Telehealth
The Senior Back-End Software Engineer will design and implement a serverless platform, work closely with the product team, and own entire projects, driving innovation in telehealth.
Top Skills: Aws ServicesJavaScriptNext.JsNode.jsSql DatabasesSstTypescript
Reposted 25 Days AgoSaved
Remote
St. Louis, MO
180K-230K Annually
Senior level
180K-230K Annually
Senior level
Software • Energy
The Power Systems Software Engineer will develop high-fidelity power flow models, validate them against customer data, and enhance the architecture for solver performance in grid simulations.
Top Skills: AmiGCPGisOpendssPower SystemsPythonScada
Reposted 25 Days AgoSaved
Remote
St. Louis, MO
130K-190K Annually
Senior level
130K-190K Annually
Senior level
Software • Database
Build and maintain scalable, cloud-native full‑stack features and services. Collaborate with Product and Design to prototype, deliver, and document solutions. Work across backend and frontend, apply modern engineering practices, mentor teammates, and own product domains to improve transit operations.
Top Skills: APIsAWSJavaJavaScriptNode.jsNoSQLPythonSQLVue
Reposted 25 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Digital Media
The Senior .NET Software Engineer will drive development of .NET software products, focusing on back-end engineering, code reviews, and collaborating with cross-functional teams.
Top Skills: APIsAzure CloudCi/CdCSSJavaScriptJSONLinqNet 6Net Mvc FrameworkReactRestSQLSwagger
Reposted 3 Days AgoSaved
In-Office or Remote
St. Louis, MO
143K-331K Annually
Senior level
143K-331K Annually
Senior level
Software • Quantum Computing • Metaverse • Infrastructure as a Service (IaaS)
Lead architecture and roadmap for Azure PostgreSQL systems; design and review scalable, maintainable database engine features (query processing, storage, transaction logging, recovery, versioning, IO, scale-out). Influence coding standards and run code reviews, write proof-of-concept or production code, contribute to open-source PostgreSQL/Linux, and participate in rotational on-call operations.
Top Skills: AzureAzure Cosmos DbAzure Data FactoryAzure Event GridAzure PostgresqlAzure Service BusAzure Sql DbAzure Synapse AnalyticsCC#C++JavaJavaScriptLinuxMicrosoft FabricPostgresPower BIPython
Reposted 9 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Software
Seeking a Staff Software Engineer to design and build cloud-deployed systems. Must have extensive programming and leadership experience in software engineering.
Top Skills: C#C++GoJava
Reposted 3 Days AgoSaved
Remote
St. Louis, MO
150K-185K Annually
Senior level
150K-185K Annually
Senior level
Artificial Intelligence • Mobile • Software
Design, build, test, and maintain production-ready, scalable API services and platform solutions using microservices and containerization. Collaborate with engineers, Data Engineers, CloudOps and Product to deploy and operate services on cloud platforms, ensure observability and readiness, and participate in Agile lifecycle activities.
Top Skills: Apache AirflowApi GatewayAWSAws CdkBashC++Ci/CdCloudFormationContainerizationDockerEc2GoGraphQLGroovyGrpcJavaKmsMicroservicesPostgresProtocol BuffersPubsubPythonRdsReactReduxRestS3TerraformVpc
Reposted 3 Days AgoSaved
Remote
St. Louis, MO
120K-261K Annually
Senior level
120K-261K Annually
Senior level
Software • Quantum Computing • Metaverse • Infrastructure as a Service (IaaS)
Design, build, and maintain highly distributed Azure cloud infrastructure services. Deliver new features, ensure high reliability and performance, monitor and alert on system health, act as DRI, and participate in on-call diagnostics and remediation.
Top Skills: CC#C++JavaAzureMicrosoft Cloud
Reposted 3 Days AgoSaved
Remote
St. Louis, MO
120K-261K Annually
Senior level
120K-261K Annually
Senior level
Software • Quantum Computing • Metaverse • Infrastructure as a Service (IaaS)
Design, build, and operate large-scale distributed host networking systems for Azure. Develop host agent services for network configuration, connectivity, and traffic orchestration; improve reliability, observability, and deployment safety; lead incident RCA and mentor engineers while driving architectural direction.
Top Skills: ArpAWSAzureC#C++DhcpDnsGoGCPHypervisorJavaJavaScriptLoad BalancingNatNdpPythonRustSdnSmartnicSnatTcp/IpVirtualization
Reposted 3 Days AgoSaved
Remote
St. Louis, MO
150K-190K Annually
Senior level
150K-190K Annually
Senior level
PropTech
As a Staff Software Engineer, you will significantly enhance platform development and experimentation, focusing on AI integration and efficient software workflows. You'll manage end-to-end processes, develop core infrastructure, and employ AI coding agents to refine engineering practices, ultimately improving velocity and output quality.
Top Skills: Ai Coding AgentsCi/CdCloud PlatformsSoftware Architecture
Reposted 3 Days AgoSaved
Remote
St. Louis, MO
175K-220K Annually
Senior level
175K-220K Annually
Senior level
Software
As a Software Engineer, AI/ML GenAI, you will design and implement AI features, manage embeddings, and optimize AI systems for production deployment while collaborating with product and design teams.
Top Skills: AWSCeleryDockerFastapiGCPNode.jsPythonRuby On RailsSQLTypescript
Reposted 3 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Blockchain • Software • Cryptocurrency • Web3
The Senior Software Engineer, Protocol will architect and develop core protocol components for a blockchain while optimizing distributed systems. Responsibilities include enhancing performance, solving distributed systems problems, and contributing to engineering standards in collaboration with research and product teams.
Top Skills: Rust
Reposted 3 Days AgoSaved
Remote
St. Louis, MO
120K-150K Annually
Senior level
120K-150K Annually
Senior level
Healthtech
Develop and maintain scalable software solutions, mentor developers, and integrate AI tools. Collaborate on technical solutions aligned with business goals.
Top Skills: .NetAngularAWSAzureAzure SqlC#Entity FrameworkGCPGitPostmanReactSQL ServerSwaggerVisual StudioVue
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