Top Senior Software Engineer Jobs in St. Louis, MO

Design, develop, secure, and maintain mission-critical Microsoft-platform software for DoD programs. Build C# and .NET applications, responsive JavaScript and EXT JS interfaces, REST APIs, and optimized SQL Server databases. Apply secure coding, STIG, RMF, threat modeling, vulnerability remediation, documentation, and compliance practices. Integrate Kiro AI capabilities, collaborate with cybersecurity and engineering teams, and support deployment and sustainment in classified or controlled environments.

Build Exoware’s production infrastructure from the ground up, including deployment, scaling, upgrades, recovery, CI/CD, monitoring, telemetry, security, and operational tooling. Design reliable systems across Kubernetes, ECS, cloud services, networking, and storage while writing software to automate operations. The role requires architectural ownership, production infrastructure experience, and the ability to improve the underlying distributed systems through production insights.

Lead front-end architecture and cross-team technical initiatives for the NodeZero platform. Build scalable React and TypeScript systems, reusable components, developer tooling, and shared frameworks while improving performance, reliability, accessibility, observability, and CI/CD workflows. Mentor engineers, establish engineering standards, guide technical strategy, reduce technical debt, and collaborate with Product, Design, Platform, Security, and engineering teams.

Build and maintain production software implementing healthcare interoperability standards, including FHIR and HL7. Develop APIs, services, data pipelines, validation logic, data models, and automated tests while preserving clinical meaning and data quality. Collaborate with engineers, data scientists, healthcare professionals, product managers, and operations staff to deliver scalable healthcare solutions.

Design, develop, and maintain RESTful APIs and scalable event-driven cloud solutions using TypeScript and AWS. Build infrastructure as code with AWS CDK, implement secure and highly available architectures, troubleshoot production issues, optimize performance, participate in technical planning and code reviews, document solutions, collaborate with teams and vendors, and mentor engineers on AWS best practices.

Design, build, and operate high-throughput, low-latency ad-serving infrastructure processing millions of requests per second. Optimize GPU-powered TensorRT inference, feature stores, model serving, benchmarking, experimentation tooling, and system reliability. Partner with machine learning engineers to productionize models and own systems through design, deployment, observability, capacity planning, incident response, and optimization.

Own end-to-end delivery of complex software features for a virtual care platform. Design scalable systems, build AI-powered agents and workflows, enhance reliable mobile and web experiences, and translate clinical and user needs into technical solutions. Collaborate with product managers, designers, and clinical staff while focusing on patient impact, product quality, and engineering efficiency.

Build production-grade test automation infrastructure across API, integration, end-to-end, contract, regression, load, and performance testing. Develop Playwright suites, integrate automated tests with GitHub Actions release gates, create AI-assisted test generation workflows, maintain coverage dashboards, reduce flakiness, and establish performance-testing frameworks. Partner with engineers and product managers to define coverage, acceptance criteria, performance thresholds, and quality standards across the organization.

Design, build, and evolve customer-facing backend services and public APIs for Chainguard’s platform. Own features end-to-end from technical design through rollout and iteration, partnering with Product and front-end teams. Develop reliable, observable cloud-native services consumed across multiple products, contribute to roadmap prioritization, and deliver iteratively in a remote startup environment.

Build core experiences for bank administrators and customers by developing streamlined user flows, robust APIs, and third-party integrations. The role emphasizes clean, documented, tested code; system design; error handling; performance; domain-driven design; microservice architecture; and technical guidance through code reviews. Candidates will primarily work with front-end technologies while contributing to backend services in an agile Scrum environment.

Design and develop the backend of the vCluster Platform using Go and deep Kubernetes expertise. Own features end to end, from technical design through release, while solving complex systems and multi-tenancy challenges. Contribute to open-source projects and Kubernetes community initiatives, build scalable isolation and resource-sharing solutions, and operate autonomously in a fast-growing startup environment.

Lead development of scalable software solutions across frontend and backend systems. Build React and TypeScript interfaces, C# .NET and Node.js services, Terraform-managed AWS infrastructure, and optimized MSSQL schemas and queries. Collaborate on requirements and roadmaps while promoting code quality, testing, RESTful architecture, and CI/CD best practices. The role also uses generative AI tools and coding agents, with preferred experience in Docker, Kubernetes, serverless computing, and automated testing.

Build and operate on-premises infrastructure for containerized AI/ML services. Responsibilities include Kubernetes orchestration, infrastructure automation, CI/CD and GitOps pipelines, observability with Prometheus and Grafana, resilient high-availability infrastructure, and collaboration with mission stakeholders, data scientists, and system administrators. The role supports reliable delivery of mission-critical AI capabilities and may involve model-serving technologies, service meshes, SIGINT systems, and CNO operations.

Design and build Kubernetes-based LLM serving infrastructure, including GPU scheduling, scaling, model lifecycle management, Helm packaging, enterprise and offline deployments, API integrations, and production observability. Develop across a multi-service Go codebase, contribute design documentation and reviews, and help guide engineering direction. The role requires strong Kubernetes, distributed systems, CI/CD, and infrastructure-as-code expertise, with GPU, inference, or adjacent systems experience.

Build, deploy, and own scalable consumer applications and services for a digital lending platform, with a focus on React frontend development. Responsibilities include designing features, automated testing, full software development lifecycle participation, collaboration with cross-functional teams, system scalability and reliability, technical debt reduction, mentoring frontend engineers, and using AI-driven coding agents and agentic workflows.

Design and build Go-based storage control-plane services, CSI drivers, integrations, and tooling for Kubernetes AI and compute workloads. Automate storage provisioning using Terraform/OpenTofu and GitOps tools, support hybrid and bare-metal deployments, and develop observability for performance and reliability. Integrate enterprise storage platforms such as Dell PowerScale and VAST across cloud, edge, and air-gapped environments, including K0rdent, Cluster API, Harbor, and PKI/TLS infrastructure.

Build and operate full-stack internal web applications and conversational AI bots using React, TypeScript, Node.js, Elasticsearch, Kibana, LLMs, RAG, and vector search. Responsibilities include technical design, development, testing, CI/CD deployment, feature flag management, production operations, and on-call support. The role also involves replacing legacy SaaS tools, integrating Elastic Stack capabilities, and using AI coding assistants to accelerate delivery.

Design, develop, and maintain complex distributed software systems. Translate product requirements into scalable, secure, modular designs; write well-tested code; lead design and code reviews; guide agile sprint teams; collaborate with stakeholders; and mentor engineers. The role also contributes to technical strategy, resolves delivery impediments, and promotes engineering best practices.

Staff Software Engineer responsible for setting technical direction, architecting scalable distributed systems, shipping high-impact features, and building AI-powered tools for a virtual healthcare platform. The role includes mentoring engineers, partnering with product and clinical leadership, translating user needs into technical solutions, and guiding frontend and backend application development in a fast-paced startup environment.

Develop and maintain secure client/server enterprise applications, appliance operating systems, release pipelines, and cloud infrastructure. Responsibilities include coding, testing, troubleshooting, patching, packaging, signing, and releasing software for on-premises and cloud deployments. The role collaborates with engineering, QA, support, and customers while managing AWS infrastructure, databases, security controls, documentation, and Agile development practices.

Leads architecture, design, development, testing, deployment, monitoring, and production ownership for complex software products. Guides engineering practices including TDD, pair programming, CI/CD, microservices, and distributed systems. Provides technical leadership across product teams, facilitates Agile ceremonies, resolves technical issues, and manages medium to large engineering teams. Advises direct reports on priorities, risks, budgets, administrative policies, and sourcing decisions while driving KPI achievement.

As a Billing & Analytics Software Engineer, you'll design and maintain the billing pipeline, integrate billing systems, and develop customer-facing analytics dashboards to support revenue recognition and operational observability.

Own and build Hercules’ billing, payments, subscriptions, usage-based billing, monetization, and commerce infrastructure. Integrate payment providers, support currencies and payment methods, and design reliable, low-latency systems with webhook processing, retries, reconciliation, and scalable usage metering. The role requires strong system design, architecture, data modeling, API design, code quality, product judgment, and proficiency with Hercules’ TypeScript-based stack, including React, Postgres, Redis, containers, and Temporal.

Build and own full-stack features across Hercules’s AI agent, app builder, hosting infrastructure, SDK, platform, and internal AI coding harness. Design scalable systems, APIs, data models, and SaaS capabilities including billing, identity, analytics, and notifications. Write maintainable code in monorepos, ship customer-facing features independently, and work with TypeScript, React, Postgres, Redis, Temporal, cloud infrastructure, and AI development tools.

Own Alkira’s global platform infrastructure, including Kubernetes clusters, CI/CD systems, shared databases and storage, service lifecycle, disaster recovery, Terraform modules, observability, and production tooling in Go or Python. Drive architectural decisions, cost reduction, reliability, security, and multi-team platform adoption while mentoring engineers and participating in on-call support.