Top Senior Software Engineer Jobs in St. Louis, MO

Leads the design, development, architecture, and maintenance of scalable software systems. Provides technical leadership, conducts code reviews, ensures development best practices, and mentors junior engineers. Collaborates with technical and non-technical stakeholders to deliver reliable solutions supporting clinical decision-making and patient outcomes.

Build performant, accessible front-end interfaces for AI agents, dashboards, conversational user interfaces, and visualization tools. Collaborate with designers, AI engineers, and backend developers to create scalable components, optimize cross-browser experiences, and iterate on UX using testing, feedback, and usage data.

Designs and architects Salesforce solutions, including data models, integrations, Apex, Visualforce, Lightning components, migrations, and security governance. Leads customization and deployment practices, translates business requirements into technical solutions, mentors administrators and developers, and provides technical leadership across Salesforce projects. Collaborates with stakeholders, ensures quality and compliance, and stays current with platform updates and emerging technologies.

Design and optimize networking infrastructure for Azure AI supercomputing clusters. Develop RDMA communication libraries, transport protocols, distributed systems, observability tools, and performance optimizations. Analyze latency, throughput, congestion, scalability, and fault tolerance across large GPU and accelerator environments. Lead technical architecture, write design specifications, resolve complex production networking challenges, and collaborate with hardware, silicon, AI framework, and infrastructure teams.

Build and scale global payments and treasury systems using resilient, event-driven microservices. Design client-facing APIs, distributed systems, financial ledgers, and payment integrations while ensuring scalability, reliability, and system integrity. Collaborate independently and cross-functionally to define and implement solutions, troubleshoot issues, and maintain clean, tested code. Work with cloud infrastructure, Kubernetes, messaging systems, relational databases, payment rails, reconciliation, and double-entry accounting.

Develop and maintain Akamai’s custom Linux kernel and distribution for a globally distributed cloud platform. Responsibilities include adding performance, reliability, and security features; porting modifications to newer kernels; debugging production and test issues; improving build and continuous-testing automation; collaborating with platform, application, test, and hardware teams; and contributing work upstream to the open-source Linux community.

Build and scale backend identity platform services for global user onboarding, identity verification, risk management, and trading accounts. Design reliable microservices and architectures, contribute to technical decisions, maintain code quality and test coverage, troubleshoot incidents, collaborate across teams, and potentially participate in on-call support.

Build and maintain MongoDB’s distributed database infrastructure for cluster scalability. Design data partitioning, data movement, dynamic scaling, workload execution, and resilient distributed protocols. Solve complex performance and low-latency systems problems, contribute production-quality C++ code, participate in design and code reviews, lead new feature development, and mentor engineers.

Leads end-to-end software development for AI-infused enterprise applications, including architecture, database design, coding, testing, deployment, and service reliability. Builds Copilot and agentic solutions using Azure and modern full-stack technologies. Provides technical leadership, mentors engineers, establishes quality and security practices, supports enterprise integrations, and collaborates with product teams, program managers, UX designers, and data scientists to deliver scalable commercial software.

Lead complex, cross-team software initiatives from design through rollout; architect backend services, improve reliability and observability, guide technical strategy, mentor engineers, and elevate engineering quality. The role emphasizes AI-assisted coding, agentic development workflows, automated guardrails, testing, incident response, and solving ambiguous technical problems across consumer applications and internal tools.

Develop and maintain Akamai’s custom Linux kernel for its cloud platform. Responsibilities include adding performance, reliability, and security features; porting modifications across kernel versions; debugging production and test issues; improving build and continuous-testing automation; collaborating with platform, application, hardware, and test teams; and contributing changes upstream to the Linux community.

Develop fullstack web applications, enhance platform performance, collaborate on high-impact opportunities, and ensure stable, scalable solutions. Engage in rapid iterations and be a committed team player.

Design, develop, and operate scalable software platforms and automation for Azure network qualification infrastructure. Build tools for device provisioning, configuration, lifecycle management, testing, telemetry, and health validation. Develop AI-powered agents for troubleshooting, root-cause analysis, and engineering productivity. Create reliable distributed systems with observability, diagnostics, automated recovery, and scalability while collaborating across software and network engineering teams.

Develop and maintain PowerUp Sports’ software platform, build and release new features, integrate technologies, optimize PHP applications on Azure, manage SQL Server databases, participate in code reviews, mentor junior developers, and support scalable, reliable architecture.

Provides technical leadership for Azure cloud-scale distributed data platforms processing network telemetry and operational data. Defines architecture and long-term technical strategy, leads streaming and batch system design, resolves complex scalability and reliability challenges, oversees production readiness and continuous improvement, and influences cross-team technical investments. Partners across Azure Networking, conducts design reviews, establishes reusable engineering patterns, improves observability and quality, and mentors engineers and technical leaders.

Build and evolve distributed platforms, microservices, intelligent agents, and AI-enabled services. Lead hands-on software development while defining agent orchestration, Infrastructure as Code, controls-as-code, CI/CD, security, and compliance practices. Partner with systems engineers and security stakeholders, translate mission needs into scalable solutions, establish development standards, mentor engineers, and guide architecture and technical decisions in secure, regulated environments.

Design and implement scalable, secure, high-performance software systems and public-facing APIs. Lead system design, apply agentic coding workflows, collaborate with Product and Data Science, mentor engineers, and own initiatives improving efficiency, performance, and customer satisfaction. The role requires extensive experience with highly available distributed systems, API versioning and rate limiting, modern backend and frontend technologies, AWS, and Domain-Driven Design.

Develop and deploy life-saving technologies as a fullstack engineer, focusing on web applications for public safety, collaborating with various engineering disciplines and leveraging customer feedback.

Design, build, test, and deliver software for managing virtual machines alongside Kubernetes workloads in secure, disconnected environments. Develop Kubernetes tooling, APIs, VM image workflows, management capabilities, and integrations for networking, storage, observability, and security. Debug complex distributed systems, improve reliability and performance, make architectural decisions, review code, mentor engineers, and collaborate with product, UX, and mission stakeholders.

Develop and optimize low-level embedded software and firmware for wireless communication systems. Integrate WiFi and 5G/LTE modules, support board bring-up, and validate hardware-software interactions. Optimize CPU, DSP, FPGA, and power performance; implement secure boot and OTA firmware updates; debug complex subsystem interactions; and collaborate with hardware and cross-functional teams. Maintain technical documentation and participate in code reviews.

Lead complex software projects and mentor engineers while building scalable full-stack products for Vanta’s expansion team. Develop purchasing, checkout, upgrade, renewal, billing, and trial experiences that support self-serve growth and revenue automation. Set technical direction, own product functionality and infrastructure, collaborate across teams, and contribute to engineering culture. The role uses TypeScript, React, and Node.js and involves greenfield development in a rapidly scaling startup environment.

Develop and operate software for Azure’s hyperscale networking infrastructure and SONiC switch and router platforms. Responsibilities include designing, coding, optimizing, debugging, and maintaining network software; supporting packet forwarding, telemetry, observability, reliability, and performance; creating design and release plans; responding to incidents; and mentoring engineers. The role requires expertise in software engineering, IP networking, distributed systems, Linux, SDN technologies, and container-based environments.

Develop and operate IAM services powering Elastic Cloud and on-premises offerings. Responsibilities include backend software development, technical design, production debugging, incident response, customer issue resolution, security and reliability improvements, and on-call participation. The role involves distributed systems, containers, virtualization, microservices, cloud platforms, Kubernetes adoption, and collaboration across globally distributed engineering teams.

Build and operate scalable AI platform infrastructure enabling secure, reliable access to foundation models and AI agents. Responsibilities include developing model gateways, provider integrations, routing, usage controls, observability, governance, and self-service platform capabilities. The role involves architecting distributed systems, improving reliability and security, collaborating across engineering and product teams, mentoring engineers, and establishing high-quality engineering practices.

Build and ship full-stack features for AHEAD’s Hatch and Unity platforms, owning work from user needs through design, implementation, testing, deployment, and support. Make architectural decisions, use AI development tools responsibly, lead code reviews, mentor engineers, collaborate with stakeholders, estimate work, manage technical risk, and help shape the engineering roadmap. The role uses Elixir and Phoenix while emphasizing adaptability, product thinking, software quality, security, and reliable delivery.