Top Machine Learning Jobs in St. Louis, MO

Reposted One Month AgoSaved
Remote
St. Louis, MO
466K-750K Annually
Senior level
466K-750K Annually
Senior level
News + Entertainment
Lead ML initiatives to improve Sales productivity and automation: define roadmap, design and deploy production ML models and AI agents, build measurement pipelines with analytics engineers, iterate from performance and seller feedback, and act as senior technical partner across product, engineering, and Sales to drive measurable revenue impact.
Top Skills: PythonSQL
Reposted One Month AgoSaved
Remote
St. Louis, MO
600K-1M Annually
Senior level
600K-1M Annually
Senior level
News + Entertainment
Lead design and execution of a modernized, Python-native AI/ML platform for AIMS: define architecture, drive migration, build migration tooling, ensure scalability, observability, cost optimization, and reliability, prototype GenAI operational tooling, and set org-wide technical standards.
Top Skills: Batch ProcessingDistributed SystemsExperiment FrameworksFeature StoresGenaiJavaLlmsModel Serving PlatformsObservability/Monitoring SystemsPythonReal-Time ServingScalaTraining Pipelines
Reposted One Month AgoSaved
Remote
St. Louis, MO
100K-720K Annually
Mid level
100K-720K Annually
Mid level
News + Entertainment
Design, develop, and scale software systems for machine learning algorithms powering personalization. Collaborate with researchers and product teams to implement production-ready, distributed solutions, enable offline experiments and A/B tests, and improve engineering practices and systems across teams.
Top Skills: AWSC#C++FlinkJavaJaxKerasLlmsPythonPyTorchScalaSparkTensorFlow
Reposted One Month AgoSaved
Remote
St. Louis, MO
Mid level
Mid level
Blockchain • Fintech • Payments • Software
Design, build, and deploy machine learning models for a payments platform, overseeing end-to-end solutions and experimentation, while monitoring models in production.
Top Skills: AirflowNumpyPandasPythonPyTorchScikit-LearnSparkSQLTensorFlow
Reposted One Month AgoSaved
Remote
St. Louis, MO
130K-187K Annually
Senior level
130K-187K Annually
Senior level
Aerospace • Defense • Manufacturing
The job involves building responsive web dashboards, advanced data visualizations, and analytics tools for unmanned aircraft systems, requiring a deep understanding of UI/UX design and data presentation.
Top Skills: AngularCSSD3.JsFigmaGraphQLHTMLJavaScriptJestMobxNumpyPandasPlotlyPythonReactRechartsRestful ApisTypescriptVueWebglZustand
Reposted One Month AgoSaved
Remote
St. Louis, MO
180K-225K Annually
Mid level
180K-225K Annually
Mid level
Information Technology • Software
As a Machine Learning Engineer, you will fine-tune transformer models, deploy machine learning solutions, and work with cross-functional teams on innovative projects.
Top Skills: PythonPyTorchTensorFlow
Reposted One Month AgoSaved
Remote
St. Louis, MO
Mid level
Mid level
Artificial Intelligence • Cloud • Machine Learning
Integrate LLMs, RAG, and agentic-AI into secure decision-support software. Design prompts and inference workflows, connect AI to backend services, evaluate outputs, build tests, document designs, and collaborate with engineering, security, and DevSecOps teams to deliver reliable mission-capable AI features.
Top Skills: Agentic AiDevsecopsInference PipelinesKubernetesLarge Language Models (Llms)OpenshiftPrompt EngineeringRetrieval-Augmented Generation (Rag)
Reposted One Month AgoSaved
Remote
St. Louis, MO
200K-245K Annually
Mid level
200K-245K Annually
Mid level
Healthtech • Other • Telehealth
The Staff ML/AI Platform Engineer will design, prototype and deploy AI/ML models, optimize pipelines, mentor junior engineers, and collaborate closely with other teams to develop machine learning solutions.
Top Skills: Aws LambdaCi/CdDockerEcrEcsSagemakerTerraform
Reposted One Month AgoSaved
Remote
St. Louis, MO
219K-328K Annually
Senior level
219K-328K Annually
Senior level
Cloud • Legal Tech • Software
Lead a team of ML engineers to design, build, and productionize LLM/GenAI and agentic systems (retrieval, tool use, orchestration). Collaborate cross-functionally with MLOps, product, and data science, review code, mentor engineers, run technical evaluations and proofs-of-concept, and ensure reliable, safe ML deployments for a large SaaS product.
Top Skills: Agentic SystemsEvaluation FrameworksFine-Tuning Foundational ModelsGenaiLlmsMlopsPrompt DesignRag (Retrieval-Augmented Generation)RetrievalTool-Calling AgentsTraining Language ModelsUnstructured Data Preprocessing
Reposted One Month AgoSaved
Remote
St. Louis, MO
117K-187K Annually
Senior level
117K-187K Annually
Senior level
Edtech
Embed with strategic higher-education partners to design, build, and ship production AI and platform integrations (LLM/RAG, LTI) across Cengage products. Own end-to-end deployments, write production code, ensure compliance and accessibility, evaluate AI safety and outcomes, mentor FDEs, and translate field learnings into product roadmap contributions.
Top Skills: AgsApi GatewayAuroraAWSCaliperCloudwatchCoppaDeep LinkingEcsEksFerpaGraphQLJavaScriptLambdaLlm ApisLti 1.3Lti AdvantageMindtapNrpsPrompt EngineeringPythonRag (Retrieval-Augmented Generation)RdsRestS3SQLTool-Calling AgentsTypescriptWebassignXapi
Reposted One Month AgoSaved
Remote or Hybrid
St. Louis, MO
144K-230K Annually
Senior level
144K-230K Annually
Senior level
Healthtech
Lead design, development, and delivery of ML, DL, and Generative AI systems for production. Apply prescriptive analytics, optimization, recommendation, and reinforcement learning. Build and evaluate models, run experiments, develop prototypes, benchmark methods, and collaborate with business partners to translate data into actionable recommendations and influence strategy.
Top Skills: Artificial Intelligence (Ai)Data VisualizationDeep LearningGenerative AiMachine Learning (Ml)OptimizationPredictive AlgorithmsPrescriptive AnalyticsRecommendation SystemsReinforcement LearningStatistical Modeling
Reposted One Month AgoSaved
In-Office or Remote
St. Louis, MO
44K-154K Annually
Senior level
44K-154K Annually
Senior level
Agency • Information Technology
Design, develop, and deploy machine learning and deep learning models; build end-to-end ML pipelines including preprocessing, training, evaluation, and deployment; perform feature engineering on large datasets; deploy and monitor models on cloud platforms; collaborate with cross-functional teams to integrate AI solutions and retrain models as needed.
Top Skills: AWSAzureCi/CdComputer VisionDockerGCPHadoopKubernetesLlmsNlpPythonPyTorchScikit-LearnSparkSQLTensorFlow
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Reposted One Month AgoSaved
In-Office or Remote
St. Louis, MO
62K-217K Annually
Senior level
62K-217K Annually
Senior level
Agency • Information Technology
Design, build, and deploy production-grade generative AI applications: orchestrate multi-agent systems, implement advanced RAG with vector DBs, fine-tune and host LLMs, optimize GenAI workflows, and deliver scalable FastAPI-based backend services with Docker and monitoring.
Top Skills: Api SecurityAsynchronous ProgrammingCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLlm QuantizationLocal LlmsModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector DatabasesVector Search
Reposted One Month AgoSaved
In-Office or Remote
St. Louis, MO
62K-217K Annually
Senior level
62K-217K Annually
Senior level
Agency • Information Technology
Design, build, and scale production Generative AI systems: multi-agent orchestration, advanced RAG with vector databases, LLM integration and fine-tuning, scalable FastAPI backends, Dockerized deployment, monitoring, and GenAI optimization for latency, cost, and reliability.
Top Skills: Async PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLocal Llm DeploymentMulti-Agent Systems (Mas)OpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector DatabasesVector Search
Reposted One Month AgoSaved
In-Office or Remote
St. Louis, MO
53K-188K Annually
Senior level
53K-188K Annually
Senior level
Agency • Information Technology
Design, build, and deploy production-grade generative AI systems: multi-agent orchestration, advanced RAG with vector databases, integrate/swap LLMs, fine-tune models, optimize prompts and latency, and containerize services with monitoring and CI/CD.
Top Skills: Api SecurityAsynchronous ProgrammingCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLocal LlmsModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchQuantizationRagTensorFlowVector Databases
Reposted One Month AgoSaved
In-Office or Remote
St. Louis, MO
48K-170K Annually
Senior level
48K-170K Annually
Senior level
Agency • Information Technology
Build and scale production Generative AI applications: design multi-agent systems and LangGraph workflows, implement advanced RAG with vector DBs, integrate and fine-tune LLMs, deploy FastAPI async services in Docker, and optimize GenAI performance, cost, and monitoring.
Top Skills: Api SecurityAsync PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLlm QuantizationLocal Model DeploymentModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector DatabasesVector Search
Reposted One Month AgoSaved
Remote
St. Louis, MO
51K-178K Annually
Senior level
51K-178K Annually
Senior level
Agency • Information Technology
Design, implement, and own end-to-end scalable ML systems and MLOps lifecycle (deployment, monitoring, metrics). Optimize models and system performance, work with Java/Python and TF/PyTorch, use CI/CD, Terraform, Docker/Kubernetes, lead inter-team communication, document work, and meet deadlines.
Top Skills: SparkCi/CdDockerGcp Ml Tech StackHadoopInfrastructure As CodeJavaKubernetesPrompt EngineeringPruningPythonPyTorchQuantizationSpeculative DecodingTensorFlowTerraform
Reposted One Month AgoSaved
In-Office or Remote
St. Louis, MO
62K-217K Annually
Senior level
62K-217K Annually
Senior level
Agency • Information Technology
Design, build, and deploy production Generative AI applications: orchestrate multi-agent workflows, implement advanced RAG with vector DBs, integrate and fine-tune LLMs, develop scalable FastAPI/async backends, containerize with Docker, and optimize GenAI systems for latency, cost, and reliability.
Top Skills: Async PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLocal LlmsMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchRagTensorFlowVector DatabasesVector Search
Reposted One Month AgoSaved
Remote
St. Louis, MO
47K-166K Annually
Senior level
47K-166K Annually
Senior level
Agency • Information Technology
Design, build, and deploy production-grade ML and AI systems end-to-end, combining classical ML, deep learning, and LLM/agentic integrations. Implement MLOps, monitoring, CI/CD, model serving, vector search/RAG pipelines, and scalable APIs; mentor engineers and drive engineering best practices.
Top Skills: AnthropicAutogenChromaCi/CdCrewaiDockerFastapiFlaskGeminiHadoopKubernetesLangchainLanggraphLlamaindexLoraMilvusMlflowNumpyOpenaiPandasPineconePrompt EngineeringPythonPyTorchQloraRagSagemakerScikit-LearnSparkSQLTensorFlowVector SearchVertex AiWeaviate
Reposted One Month AgoSaved
Remote
St. Louis, MO
128K-165K Annually
Senior level
128K-165K Annually
Senior level
Financial Services
The Senior Analyst in Predictive Analytics and Machine Learning develops and maintains statistical models to support business decisions, monitors model performance, and collaborates with stakeholders across the company.
Top Skills: PythonRSASSQL
One Month AgoSaved
Remote
St. Louis, MO
118K-174K Annually
Mid level
118K-174K Annually
Mid level
Cloud • Information Technology • Software
Develop and support Rescale's HPC platform, integrate AI into CAE workflows, solve customer HPC/AI problems, build AI software, collaborate with engineering teams, and engage directly with customers.
Top Skills: CaeCfdCudaFeaHpcKubernetesModulusPygPyTorchRest Api
One Month AgoSaved
Remote
St. Louis, MO
Junior
Junior
Artificial Intelligence • Logistics • Software • Automation
Design, train, evaluate, deploy, and monitor machine learning models. Prepare and analyze large datasets, improve model performance through experiments, and collaborate with software engineers to integrate ML solutions into production while staying current with ML techniques.
Top Skills: AWSAzureGCPGitLarge Language Models (Llms)PythonPyTorchScikit-LearnSQLTensorFlow
Reposted One Month AgoSaved
Remote
St. Louis, MO
80K-120K Annually
Senior level
80K-120K Annually
Senior level
Artificial Intelligence • Software • Generative AI
Lead relevance evaluation and quality improvements by fine-tuning LLMs, building low-latency reranking and filtering systems, scaling LLM deployments, creating automated monitoring pipelines and agentic insights, and validating impact via A/B tests while collaborating with cross-functional teams.
Top Skills: AirflowLlmsPythonPyTorchSparkSQL
Reposted One Month AgoSaved
Remote
St. Louis, MO
Mid level
Mid level
Edtech
The role involves developing and deploying machine learning solutions, optimizing models, and collaborating with cross-functional teams. Responsibilities include cloud architecture, algorithm engineering, and infrastructure best practices.
Top Skills: Aws EcsAws LambdaC++DockerJavaOnnxPythonPyTorchScikit-LearnTensorFlow
Reposted One Month AgoSaved
Remote
St. Louis, MO
Expert/Leader
Expert/Leader
Insurance
Build and validate production-grade ML and AI systems across pricing, underwriting, claims, and portfolio management. Work with structured and unstructured data, LLMs and agentic workflows, extract information from documents, resolve entities, create feature pipelines and inference services, quantify uncertainty, monitor drift, and measure business impact in collaboration with engineers, actuaries, underwriters, and product teams.
Top Skills: Agentic AiAnomaly DetectionAPIsAWSAzureCausal InferenceCi/CdClassificationContainersData PipelinesDeep LearningEntity ResolutionExperiment TrackingExtreme Value TheoryFeature PipelinesFoundation ModelsGCPGradient BoostingHierarchical ModelsInformation ExtractionLlmsMlopsModel Inference ServicesModel MonitoringOrchestrationRankingRecommendationShrinkage EstimationSurvival Analysis
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