Top Machine Learning Jobs in St. Louis, MO

Leads an engineering team building and scaling customer-facing integrations for agentic AI products. Responsibilities include setting technical direction, balancing customer delivery with reusable tooling and platform investments, ensuring reliability and observability, improving developer experience, collaborating cross-functionally, recruiting, and coaching engineers. The role requires customer empathy, strong engineering leadership, technical problem-solving, and experience with production systems or integrations.

Assess AI-enabled products and software against regulatory requirements and standards, supporting conformity assessments, CE marking, certification, and client guidance. Review technical documentation, mentor colleagues, develop assessment procedures and tools, contribute to AI testing methodologies, and support accreditation, quality, and continuous improvement activities. The role requires practical AI/ML experience, regulatory knowledge, strong analytical skills, and collaboration across global multidisciplinary teams.

Develop and optimize large-scale advertising ranking models for CTR and CVR prediction, calibration, user representations, and sequence modeling. Own machine learning systems end to end, including data pipelines, feature engineering, training, evaluation, deployment, and maintenance. Collaborate with platform, product, data science, and engineering teams to run experiments and improve advertiser outcomes, revenue, and user relevance. Apply deep learning and recommendation techniques within production latency, reliability, and cost constraints.

Lead research and experimentation to measure ad campaign performance and effectiveness. Design evaluation frameworks, build measurement solutions, develop models for lift, conversion, and attribution, run experiments and analyses, partner with product/engineering/design/sales, present insights, mentor teammates, and foster technical community and culture.

Build and operate scalable, highly available ML/LLM serving and compute infrastructure. Own long-term platform vision, deliver zero-to-one projects, partner cross-functionally, optimize performance and capacity, and support production ML models at scale.

Design, productionize, and deploy machine learning forecasting models for ad inventory and campaign performance in low-latency, real-time advertising environments. Build scalable simulation, budgeting, and pacing systems; collaborate with cross-functional teams to deploy models at scale and optimize ad monetization.

Lead design, execution, and optimization of scaled lifecycle campaigns across email and in-product channels. Use marketing automation, behavioral data, and ML techniques to personalize journeys, drive activation, revenue, retention, and cross-sell. Analyze performance, generate insights, and collaborate with Growth, Product, Engineering, Data Science, Analytics, Sales, and Marketing stakeholders.

Lead design, execution, and interpretation of A/B tests and quasi-experiments; apply causal inference methods; partner with product, engineering, and marketing; mentor data scientists; build experimentation frameworks; extract and analyze data using SQL and Python; communicate results to stakeholders.

Lead the hands-on development of Vida’s secure data and AI/ML platform, including ingestion, data modeling, MLOps, model serving, feature pipelines, LLM integrations, DevOps, observability, and infrastructure. Partner with security and IT to protect sensitive health data and meet HIPAA/HITRUST-aligned controls while establishing scalable engineering patterns across the organization.

Lead the architecture, implementation, governance, and operation of enterprise AI agents using Amazon Bedrock AgentCore. Design agents, knowledge bases, action groups, orchestration workflows, registries, guardrails, and emergency shutdown controls. Guide ECS deployments, API Gateway integrations, IAM governance, authentication, and platform standardization. Provide technical leadership to engineering and DevOps teams while collaborating with AWS specialists, customers, and business stakeholders.

Conduct machine learning research operations using existing infrastructure. Characterize neural network quality, failure modes, and edge cases; coordinate experiments with researchers; manage concurrent experiments and deadlines; review results; recommend theoretical or process improvements; and prepare technical reports communicating qualitative and quantitative findings.

The Senior Product Manager will set product direction, own the development lifecycle, collaborate with teams, and ensure high-quality outputs. This role requires strong opinions on product quality and customer insights.

The Enterprise Account Executive drives revenue through high-value contracts, managing complex sales processes and relationships with executive stakeholders in financial services.

Lead the Decision Science function, designing ML models, overseeing experimentation frameworks, and ensuring model adoption across the company, driving operational and commercial improvements.

Lead assessment, redesign, and hands-on implementation of data pipelines, ML workflows, and platform infrastructure. Produce prioritized system designs, harden production pipelines, improve observability, reliability, and data quality, and mentor the data team.

Lead design and build of a cloud-based big data analytics platform: implement analytics infrastructure, integrate streaming and batch data, develop distributed processing pipelines, manage predictive analytics models, and apply machine learning and Bayesian methods. Work involves Scala on OS X and AWS, Java and Clojure, Kafka/Samza, NoSQL, and following TDD, Agile, CI/CD practices.

Develops AI/ML prototypes, APIs, microservices, integrations, and lightweight user interfaces for federal and DoD-aligned mission workflows. The role integrates and optimizes machine learning models for dashboards and applications, supports data ingestion and preprocessing, validates performance, and helps transition models into production. Collaboration with data scientists, architects, developers, PMO leadership, and cybersecurity teams is required. The position requires five years of relevant experience, a bachelor’s degree, ITIL v4 Foundation certification, and Public Trust or active Secret clearance.

Designs AI/ML pilots, predictive analytics and anomaly detection models, behavioral analytics, content classification, personalization algorithms, and end-to-end machine learning pipelines. Develops prototypes and production-ready solutions, evaluates AI technologies, supports experimentation, integrates ML insights into dashboards, and ensures model governance, explainability, bias mitigation, accuracy, and security compliance in federal and DoD-aligned environments.

Lead go-to-market and partner development for Personal Loans and Point-of-Sale products. Own end-to-end enterprise sales, build C-level relationships, close complex deals, and coordinate cross-functional teams to launch AI-driven consumer lending integrations and scale market presence.

Author and verify rigorous multiple-choice computer science assessment items across many CS domains to create gold-standard benchmarks for AI research. Produce correct answers, nine plausible distractors, solution explanations, difficulty labels, and authoritative references. Review and edit questions for technical accuracy, clarity, and reproducibility. Contribute asynchronously as an independent contractor, ~10+ hours/week, fully remote.

Develop, deploy, and optimize scalable machine learning solutions, including predictive models, deep learning systems, data pipelines, and model-serving infrastructure. Monitor model performance, manage retraining and lifecycle processes, ensure quality and compliance, and support responsible AI practices. Collaborate with data scientists, engineers, product teams, and business stakeholders while researching emerging AI technologies and improving AI architectures.

Leads the architecture, development, deployment, and optimization of enterprise machine learning solutions. Responsibilities include designing scalable ML systems, developing predictive models, supporting MLOps and model lifecycle management, improving data quality and feature engineering, implementing governance and validation frameworks, and mentoring technical teams. The role also contributes to AI strategy, innovation initiatives, responsible AI practices, and organizational modernization.

Lead design and implementation of end-to-end data science architectures for multi‑INT geospatial intelligence. Build production Python pipelines, apply ML, network analytics, and advanced spatial techniques, create interactive visualizations and dashboards, mentor team members, liaise with stakeholders, and produce mission-ready intelligence products adhering to IC standards.

Define and execute the product roadmap for AI-driven on-chain monitoring tools to detect blockchain threats. Collaborate with engineering, research, and stakeholders, analyze market and customer feedback, prioritize features, ensure timely delivery, and maintain transparent communication across teams.

Lead a global manufacturing engineering organization to standardize processes, drive lean continuous improvement, deploy automation and Industry 4.0 solutions (cobots, ML), and ensure safety, traceability, and zero-defect customer quality across international sites.