Top Machine Learning Jobs in St. Louis, MO

Reposted 4 Days AgoSaved
Remote
St. Louis, MO
248K-310K Annually
Senior level
248K-310K Annually
Senior level
Real Estate • Travel • PropTech
Responsible for fine-tuning state-of-the-art LLMs, optimizing models for deployment, and driving AI architectural decisions. Collaborate with cross-functional teams to develop impactful AI products.
Top Skills: PythonPyTorch
Reposted 4 Days AgoSaved
Remote
St. Louis, MO
200K-245K Annually
Mid level
200K-245K Annually
Mid level
Healthtech • Other • Telehealth
The Staff ML/AI Platform Engineer will design, prototype and deploy AI/ML models, optimize pipelines, mentor junior engineers, and collaborate closely with other teams to develop machine learning solutions.
Top Skills: Aws LambdaCi/CdDockerEcrEcsSagemakerTerraform
Reposted 4 Days AgoSaved
Remote
St. Louis, MO
210K-275K Annually
Senior level
210K-275K Annually
Senior level
Healthtech • Information Technology • Software • Consulting
The Director of AI & ML is responsible for establishing and leading the AI function, defining AI strategy, building a high-performing team, and delivering production-grade ML and AI solutions within healthcare payer workflows.
Top Skills: AIAWSGenerative AiHuggingfaceLlmMlMlopsPythonPyTorchTensorFlow
5 Days AgoSaved
Remote
St. Louis, MO
160K-220K Annually
Senior level
160K-220K Annually
Senior level
Software • Analytics • Cybersecurity
Design, build, and own production ML and LLM-driven features (RAG, prompt engineering, fine-tuning, semantic search). Write maintainable code, create design docs, troubleshoot issues, collaborate with product/design, and participate in Agile development. Work with Python/Java/JavaScript, ML frameworks, and cloud/container technologies.
Top Skills: DockerFew-Shot LearningFine-TuningHugging FaceJavaJavaScriptKerasKnowledge DistillationKubernetesLarge Language Models (Llms)MxnetNode.jsPostgresPrompt EngineeringPythonPyTorchRetrieval-Augmented Generation (Rag)Scikit-LearnSemantic SearchTensorFlow
5 Days AgoSaved
Remote
St. Louis, MO
286K-457K Annually
Expert/Leader
286K-457K Annually
Expert/Leader
Software
Drive technical direction and architecture for AI Context systems across HubSpot's CRM: develop, evaluate, productionize, and monitor ML/LLM models; build scalable data processing, retrieval, feature generation, and serving systems; lead cross-team initiatives, mentor engineers, and measure customer and business impact while addressing privacy, bias, security, reliability, cost, and data governance.
Top Skills: Context RetrievalEmbeddingsEvaluation SystemsExperimentationFeature GenerationInferenceLarge Language ModelsModel-ServingMonitoringPyTorchRetrievalScikit-LearnTensorFlowTransformers
5 Days AgoSaved
Remote
St. Louis, MO
139K-204K Annually
Mid level
139K-204K Annually
Mid level
Productivity • Software • Conversational AI
Design, build, and operate cloud-native data and ML infrastructure for real-time and batch workloads. Implement reproducible training, evaluation, and inference pipelines; integrate event streams; monitor data quality, model performance, latency, and cost; automate deployments with IaC and CI/CD; collaborate with product, data science, and security teams; produce docs, dashboards, and runbooks.
Top Skills: AirflowAWSAzureBigQueryDagsterDockerFlinkGCPKafka StreamsKubernetesMlflowPythonRedshiftSagemakerSnowflakeSparkSQLVertex Ai
Reposted 5 Days AgoSaved
Remote
St. Louis, MO
45-55 Hourly
Internship
45-55 Hourly
Internship
Financial Services
The Applied Scientist AI/ML Intern will work on building data pipelines, finetuning LLMs, and deploying AI models in a collaborative team environment.
Top Skills: AIComputer VisionLarge Language ModelsMlNatural Language ProcessingPyTorchTensorFlow
Reposted 5 Days AgoSaved
Remote
St. Louis, MO
Mid level
Mid level
Information Technology • Software • Consulting
The role involves designing and building AI components for a platform, specifically focusing on NLP and ML for catalog mapping and anomaly detection, along with feedback mechanisms.
Top Skills: Huggingface TransformersNumpyPandasPythonSap CpiSap S/4HanaScikit-LearnSpacy
Reposted 5 Days AgoSaved
Remote
St. Louis, MO
220K-260K Annually
Senior level
220K-260K Annually
Senior level
Artificial Intelligence • Healthtech • Software
As a Staff Machine Learning Research Scientist, you will lead ML research, develop evaluation frameworks, mentor researchers, and collaborate on clinical AI solutions.
Top Skills: AirflowAWSDeepspeedGitJaxKubernetesPythonPyTorchSlurmSnowflakeTorchtune
Reposted 5 Days AgoSaved
Remote
St. Louis, MO
180K-210K Annually
Senior level
180K-210K Annually
Senior level
eCommerce • Insurance • Software
Lead a team of machine learning data scientists, overseeing model development for fraud detection and risk assessment, and ensuring quality throughout the model lifecycle while mentoring the team.
Top Skills: AWSPythonPyTorchScikit-LearnSQLXgboost
Reposted 5 Days AgoSaved
Remote
St. Louis, MO
Mid level
Mid level
Edtech
The role involves developing and deploying machine learning solutions, optimizing models, and collaborating with cross-functional teams. Responsibilities include cloud architecture, algorithm engineering, and infrastructure best practices.
Top Skills: Aws EcsAws LambdaC++DockerJavaOnnxPythonPyTorchScikit-LearnTensorFlow
Reposted 15 Days AgoSaved
In-Office or Remote
St. Louis, MO
73K-171K Annually
Senior level
73K-171K Annually
Senior level
Information Technology
The Lead Machine Learning Engineer will optimize AWS SageMaker, manage ML pipelines, develop infrastructure as code with Terraform, build CI/CD pipelines, and collaborate with data scientists to deploy models in production.
Top Skills: Amazon SagemakerApi GatewayAWSAws LambdaDynamoDBGithub ActionsPythonServerless ArchitecturesSqsTerraform
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6 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Artificial Intelligence • Edtech • HR Tech • Software
Design, build, deploy, and operate production-grade AI/ML and LLM systems (including RAG and agentic pipelines). Integrate AI capabilities with product workflows, run evaluation and monitoring, optimize model and system performance, and apply strong engineering practices (testing, CI/CD, versioning).
Top Skills: Ci/CdCloudLlmsPythonRag
6 Days AgoSaved
Remote
St. Louis, MO
165K-190K Annually
Senior level
165K-190K Annually
Senior level
Big Data
Design and implement production ML features, close behavior gaps with common frameworks, investigate divergences, improve performance and stability, and document designs and tests for geospatial and large-scale ML workflows.
Top Skills: C++JavaScalaScikit-LearnSpark MlXgboost
6 Days AgoSaved
In-Office or Remote
St. Louis, MO
144K-230K Annually
Senior level
144K-230K Annually
Senior level
Healthtech
Lead design, development, and delivery of ML, DL, and Generative AI systems for production. Apply prescriptive analytics, optimization, recommendation, and reinforcement learning. Build and evaluate models, run experiments, develop prototypes, benchmark methods, and collaborate with business partners to translate data into actionable recommendations and influence strategy.
Top Skills: Artificial Intelligence (Ai)Data VisualizationDeep LearningGenerative AiMachine Learning (Ml)OptimizationPredictive AlgorithmsPrescriptive AnalyticsRecommendation SystemsReinforcement LearningStatistical Modeling
6 Days AgoSaved
In-Office or Remote
St. Louis, MO
Senior level
Senior level
Agency • Information Technology
Design, develop, and deploy end-to-end machine learning models using statistical and ML algorithms. Prepare and enrich data, implement scalable PySpark/Databricks solutions, and collaborate with product and engineering to create personalized customer experiences and actionable insights.
Top Skills: DatabricksJupyter NotebooksNumpyPandasPysparkPythonPyTorchScikit-LearnSparkTensorFlow
6 Days AgoSaved
Remote
St. Louis, MO
48K-168K Annually
Expert/Leader
48K-168K Annually
Expert/Leader
Agency • Information Technology
Design, deploy, and optimize cloud-native ML systems on AWS, integrate foundation models (Bedrock/Anthropic), build and monitor SageMaker pipelines and data pipelines, detect drift, extend ML infra and libraries, and collaborate cross-functionally to deliver secure, cost-efficient production ML services.
Top Skills: Anthropic Llm ApisApache IcebergAthenaAws SdkBedrockCdkCloudwatchDockerEksGithub ActionsGlueGraphQLGuarddutyIamJavaJavaScriptKerasKinesisKmsLambdaLinuxModel RegistryPythonPyTorchRestSagemakerSagemaker PipelinesSpring BootStep FunctionsTensorFlowTerraformTypescriptVpc
6 Days AgoSaved
Remote
St. Louis, MO
72K-254K Annually
Expert/Leader
72K-254K Annually
Expert/Leader
Agency • Information Technology
Lead and deliver end-to-end AI/ML and data engineering solutions for investment banking and equity markets. Architect scalable data ecosystems, drive data integration and governance, mentor teams, collaborate with stakeholders, and enable visualization and front-end experiences to support business goals.
Top Skills: Ai/Ml PlatformsAWSAzureBig-Data FrameworksData PipelinesFront-End Development (Data Visualization)GCPPython
6 Days AgoSaved
Remote
St. Louis, MO
48K-170K Annually
Senior level
48K-170K Annually
Senior level
Agency • Information Technology
Design, develop, fine-tune, and deploy generative AI models (GANs, VAEs, transformers). Collaborate with cross-functional teams, troubleshoot model issues, document work, and communicate technical concepts to non-technical stakeholders while staying current on research.
Top Skills: BertDeep LearningGansGptNlpPrompt EngineeringPythonPyTorchTensorFlowTransformer ModelsVaes
6 Days AgoSaved
In-Office or Remote
St. Louis, MO
42K-148K Annually
Senior level
42K-148K Annually
Senior level
Agency • Information Technology
Design, develop, fine-tune, and deploy generative AI models using deep learning and transformer architectures. Collaborate cross-functionally, troubleshoot model issues, optimize performance, document work, and communicate technical concepts to non-technical stakeholders.
Top Skills: Bert)Deep LearningGansNlpPrompt EngineeringPythonPyTorchTensorFlowTransformers (GptVaes
6 Days AgoSaved
In-Office or Remote
St. Louis, MO
62K-217K Annually
Senior level
62K-217K Annually
Senior level
Agency • Information Technology
Design, build, and scale production Generative AI applications: multi-agent systems, advanced RAG pipelines, LLM integration and fine-tuning, scalable FastAPI backends, vector search, monitoring, and Dockerized deployments.
Top Skills: Async PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLocal LlmsLocal Model QuantizationModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector DatabasesVector Search
6 Days AgoSaved
Remote
St. Louis, MO
47K-166K Annually
Senior level
47K-166K Annually
Senior level
Agency • Information Technology
Design, build, and deploy production-grade ML and AI systems end-to-end, combining classical ML, deep learning, and LLM/agentic integrations. Implement MLOps, monitoring, CI/CD, model serving, vector search/RAG pipelines, and scalable APIs; mentor engineers and drive engineering best practices.
Top Skills: AnthropicAutogenChromaCi/CdCrewaiDockerFastapiFlaskGeminiHadoopKubernetesLangchainLanggraphLlamaindexLoraMilvusMlflowNumpyOpenaiPandasPineconePrompt EngineeringPythonPyTorchQloraRagSagemakerScikit-LearnSparkSQLTensorFlowVector SearchVertex AiWeaviate
6 Days AgoSaved
In-Office or Remote
St. Louis, MO
62K-217K Annually
Senior level
62K-217K Annually
Senior level
Agency • Information Technology
Design, build, and deploy production Generative AI applications: orchestrate multi-agent workflows, implement advanced RAG with vector DBs, integrate and fine-tune LLMs, develop scalable FastAPI/async backends, containerize with Docker, and optimize GenAI systems for latency, cost, and reliability.
Top Skills: Async PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLocal LlmsMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchRagTensorFlowVector DatabasesVector Search
6 Days AgoSaved
In-Office or Remote
St. Louis, MO
79K-276K Annually
Senior level
79K-276K Annually
Senior level
Agency • Information Technology
Build and scale production Generative AI applications: design multi-agent systems and LangGraph workflows, implement advanced RAG with LlamaIndex and vector DBs, integrate and fine-tune various LLMs, and deploy containerized FastAPI services with monitoring, CI/CD, and performance/cost optimizations.
Top Skills: Api SecurityAsync PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiGenai OptimizationHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLlm QuantizationLocal Llm DeploymentModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector DatabasesVector SearchWorkflow Design
6 Days AgoSaved
In-Office or Remote
St. Louis, MO
62K-217K Annually
Senior level
62K-217K Annually
Senior level
Agency • Information Technology
Design, build, and deploy production-grade generative AI applications: orchestrate multi-agent systems, implement advanced RAG with vector DBs, fine-tune and host LLMs, optimize GenAI workflows, and deliver scalable FastAPI-based backend services with Docker and monitoring.
Top Skills: Api SecurityAsynchronous ProgrammingCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLlm QuantizationLocal LlmsModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector DatabasesVector Search
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