Top Machine Learning Jobs in St. Louis, MO

Lead production-grade ML systems: build data pipelines, training and evaluation workflows, and scalable GPU inference. Fine-tune and adapt large models (LoRA, QLoRA, SFT, DPO, distillation), optimize deployments for latency/cost/reliability, and collaborate with product and engineering to ship robust, observable model-driven features.

Leads the end-to-end execution layer for machine learning, including data pipelines, large-model training and fine-tuning, evaluation, inference, deployment, monitoring, and reliability. Designs scalable GPU-based systems, optimizes performance and cost, partners with research and application engineering, and translates model capabilities into measurable production improvements. Also provides technical leadership, judgment, and support for high-impact ML delivery.

Lead the end-to-end ML execution: build and operate data pipelines, training and evaluation systems, and scalable inference. Fine-tune and optimize large models (LoRA/QLoRA/SFT/DPO/distillation), ensure GPU efficiency, monitor production quality, collaborate with product and application engineering, and rapidly ship reliable, safe ML solutions that translate research into production.

Design, build, and operate large-scale ML systems across data, training, evaluation, inference, and deployment. Lead GPU-optimized training and inference pipelines, ensure reliability, performance, safety, and seamless integration into products. Own production deployments, monitoring, and cross-functional best practices to drive measurable model improvements and efficient research-to-production cycles.

Partner with healthcare clients to discover, design, and deliver production-grade AI/LLM solutions. Architect cloud-native systems, build and deploy ML/LLM applications, prototype rapidly, troubleshoot distributed systems, and lead client engagements to drive measurable business outcomes while collaborating across product, platform, and engineering teams.

Lead B2B activation marketing to drive patient starts from commercial referral channels by building scalable systems, attribution frameworks, and repeatable playbooks. Implement MarTech and data-driven strategies, run A/B and incrementality tests, automate campaign execution using AI/ML and LLM tools, and templatize activation campaigns while managing and growing a cross-functional team.

Lead technical project success for enterprise AI infrastructure engagements. Collaborate with engineers, clients, and account leaders to capture requirements, decisions, dependencies, risks, and tradeoffs. Track constraints involving security, compliance, data sovereignty, procurement, and restricted environments. Maintain project visibility, align deliverables with business objectives, resolve issues, support implementation-to-operations handoffs, and identify expansion and renewal opportunities. Translate complex technical concepts for engineering, business, and executive stakeholders.

Analyze business processes, data quality, and datasets to identify AI and automation opportunities. Translate business requirements into AI/ML use cases, collaborate on model development, evaluate model performance, and deliver dashboards and reports. The role also supports data validation, AI solution monitoring, emerging technology research, governance, compliance, responsible AI, prompt engineering, and generative AI initiatives while partnering with business, data science, engineering, and product teams.

Manage post-sales relationships with a portfolio of customers, primarily financial institutions, to drive adoption and business outcomes from BioCatch’s behavioral biometric solution. Responsibilities include strategic consulting, project coordination, risk and escalation management, customer presentations, quarterly business reviews, roadmap feedback, stakeholder communication, team coaching, statements of work, and identifying expansion opportunities with account managers.

Lead design and implementation of Headway's insurance systems (eligibility, pricing, matching, claims). Build data-intensive, ML-powered platforms and automation, mentor engineers, write high-impact code, and improve accuracy and reliability across state and payer complexity to scale insurance-covered therapy.

Leads business analysis, advanced analytics, KPI development, data modeling, reporting automation, and AI/ML initiatives supporting global data-center construction and operational excellence. Builds datasets, dashboards, performance metrics, forecasts, and scenario models; translates complex findings for executives; aligns technology solutions with business needs; and promotes data governance, documentation, process improvement, and analytics maturity across cross-functional teams.

Owns the roadmap, problem definition, business cases, prioritization, and delivery for a core fintech platform area. Partners with product owners, engineering, data science, marketing, sales, clients, and support to develop scalable, data- and AI-driven capabilities. Monitors adoption, time-to-value, and retention, supports go-to-market activities, incorporates customer feedback, and addresses regulatory and compliance requirements.

Design, productionize, and scale machine learning and optimization models, pipelines, libraries, and deployment platforms. Partner with data scientists, engineers, product managers, and business stakeholders to deliver ML capabilities, personalization systems, and reusable end-to-end workflows. Establish ML engineering best practices, troubleshoot data pipelines, mentor junior professionals, and help define BetterHelp’s ML platform strategy.

Manage enterprise metadata, business glossaries, data catalogs, and end-to-end data lineage for a federal case management modernization program. Configure governance and metadata platforms, integrate data sources and pipelines, establish standards and workflows, monitor metadata quality, support compliant data sharing, develop governance metrics, document procedures, and train data stewards and business users.

Own customer outcomes from discovery through production deployment. Build decision systems using ontologies, reasoning, graph analytics, optimization, and machine learning over enterprise data. Write Python, SQL, and PyRel; debug unfamiliar systems; tune performance; harden deployments; document reusable solutions; and upstream platform improvements. Lead technical workshops and proofs of concept while partnering closely with customers, Product, and Engineering.

Drive new-logo sales and revenue growth for Wonderlic’s talent assessment and employee development solutions. Identify and prospect target clients, build relationships with HR and recruiting decision-makers, manage opportunities through the full sales cycle, close new business, and transition customers to Customer Success. Maintain expertise in products, market trends, and competitive conditions while providing strategic insights. The role requires B2B SaaS and HR technology sales experience, quota achievement, pipeline generation, and experience selling to SMB, mid-market, and enterprise buyers.

Instructor-led AI and machine learning training covering theory, data preprocessing, algorithms, model building, analytics, real-time projects, case studies, and practical business and IT applications. Participants use Python, TensorFlow, and Scikit-learn and receive certification upon successful completion.

Own strategic partnerships with CPG customers, driving measurable outcomes, platform adoption, user expansion, and retention. Analyze usage data and business context to identify risks and opportunities, develop success plans, lead executive and operational relationships, and advocate for customers internally. Collaborate with product, sales, marketing, and support teams while contributing to repeatable playbooks, thought leadership, and customer best practices.

Build and maintain Quora’s machine learning platform and distributed model-serving infrastructure. Develop scalable systems for recommendation and language models, optimize GPU serving latency, throughput, and cost, improve ML tooling and feature stores, and contribute to platform modernization. The role includes production deployment, collaboration with senior engineers, mentoring, and participation in an on-call rotation.

Conduct applied research on scalable optimization and resource-allocation algorithms for large communication networks. Apply machine learning, reinforcement learning, integer optimization, graph-based methods, and metaheuristics to improve solution quality and efficiency. Collaborate with software engineers to integrate algorithms into production aerospace networking systems, evaluate performance at realistic scale, publish research, support patent applications, and document novel methods.

Build and maintain computer vision and machine learning pipelines for automated device inspection, grading, and quality assessment. Responsibilities include data preparation, feature engineering, model training and evaluation, production Python development, monitoring, annotation workflows, documentation, code reviews, and collaboration with product and operations teams. The role supports the full ML lifecycle and offers increasing ownership under senior engineering guidance.

Manage the operational integrity of an automated group health insurance underwriting workflow. Review and approve RFPs, validate broker and external data, correct errors, monitor funnel and risk metrics, analyze quote-to-bind performance, triage inquiries, coordinate with sales and health plan operations, and maintain underwriting dashboards and reporting.

Lead AI agent optimization efforts by designing systems that improve token efficiency, response time, reliability, and output quality. Build agentic coding systems, develop AI application patterns, own features end to end, collaborate with engineering and field teams, support the developer community, and create public technical documentation. Work across Python, TypeScript, Java, and Go while serving as a domain expert in agent design and optimization.

Design and productionize machine learning, deep learning, LLM, personalization, recommendation, search, and retrieval systems. Collaborate with product, engineering, and analytics teams to deploy AI solutions that improve customer experiences, business growth, and operational efficiency. The role requires driving projects from ideation through deployment and delivering measurable business impact in a fast-moving fintech environment.

Own the full lifecycle of production classification and detection models, including transformer fine-tuning, entity detection, behavioral risk scoring, training, serving, versioning, evaluation, drift detection, and retraining. Build SageMaker-based ML systems and define output contracts supporting audit and policy enforcement. Lead the evaluation harness and mentor a co-op while operating as the company’s sole ML engineer.