Top Senior Machine Learning Jobs in St. Louis, MO

Lead design and scaling of a unified fraud and risk platform. Define product strategy, own fraud metrics, run SQL-driven analysis and A/B tests, and partner with engineers and data teams to build real-time detection, identity verification, and transaction monitoring. Balance customer experience with risk mitigation and communicate impact to executives, legal, and partners.

Lead Felix's global pricing strategy and infrastructure. Define monetization trade-offs, run advanced pricing experiments and elasticity research, partner with Finance on unit economics, and collaborate with Engineering to build automated/ML-driven pricing engines while keeping pricing transparent and user-friendly.

Lead design, build, and operate an end-to-end Identity Platform for KYC/KYB, overseeing CIP, CDD, sanctions screening, and continuous risk monitoring. Drive AI-first automation to reduce manual reviews, mentor engineers, manage reliability and incidents, and represent technical solutions to customers and regulators. Partner cross-functionally to shape roadmap and ensure regulatory compliance and extensibility across jurisdictions.

The Sr. Machine Learning Engineer will develop and deploy ML solutions for healthcare, manage data pipelines, and work with large datasets to enhance healthcare delivery.

As a Staff Applied ML Scientist, you will develop and maintain fraud detection models, conduct research on fraud types, and collaborate across teams to drive product development and real-time decision-making.

As a Senior Applied ML Scientist, you'll develop fraud detection models, research new fraud types, and write production code while collaborating across teams to enhance SentiLink's identity verification solutions.

Lead design, build, and scale backend and frontend components for Pearl's clinical product suite. Own engineering architecture and deployments, integrate systems with ML/computer vision pipelines, use AI-assisted development tools to accelerate delivery, improve engineering velocity and quality, and mentor teammates in AI-augmented workflows.

Lead design and build of a cloud-based big data analytics platform: implement analytics infrastructure, integrate streaming and batch data, develop distributed processing pipelines, manage predictive analytics models, and apply machine learning and Bayesian methods. Work involves Scala on OS X and AWS, Java and Clojure, Kafka/Samza, NoSQL, and following TDD, Agile, CI/CD practices.

Lead Data Science initiatives, build AI/ML solutions, and mentor teams in a collaborative environment, driving innovation in a leading construction equipment venture.

The Senior Product Manager will set product direction, own the development lifecycle, collaborate with teams, and ensure high-quality outputs. This role requires strong opinions on product quality and customer insights.

Lead the Decision Science function, designing ML models, overseeing experimentation frameworks, and ensuring model adoption across the company, driving operational and commercial improvements.

Lead design and delivery of a unified, real-time billing platform that embeds AI/ML to automate reconciliations, detect anomalies, enable predictive insights, and create autonomous finance workflows across global billing operations.

Lead product marketing for ExtraHop's Agentic SOC, shaping category narrative, translating customer and partner insights into launches, sales enablement, content, and go-to-market programs while engaging security practitioners, product, and partners to drive adoption of AI-powered security operations.

Lead and scale engineering teams building Protect, a real-time multi-signal fraud detection platform. Set technical strategy, develop managers and senior engineers, deliver distributed systems and APIs, improve architecture, observability, reliability, and developer productivity while partnering with Product, Research, Security, and exec stakeholders.

As a Senior Machine Learning Engineer, you'll design and develop workflows utilizing vision-language models, manage data pipelines, and collaborate with multiple teams to enhance model accuracy and efficiency.

As a Staff Software Engineer, you will lead the development of computer vision systems for sidewalk inspection, overseeing model lifecycle, system architecture, and mentoring while improving deployment practices.

As a Principal Software Engineer, you'll architect and code backend services and ML models, integrate them with Salesforce, and mentor junior engineers.

The Staff Product Manager will define product strategy, lead the product lifecycle, collaborate across teams, and drive innovation in claims processing software.

The Director of System Safety oversees safety functions for autonomous vehicles, managing safety cases, deployment plans, and regulatory relationships while leading a multi-disciplinary safety team.

The Senior Technical Product Manager will lead the roadmap for Aledade's AI Data Platform, collaborating with various teams to enhance AI capabilities and improve healthcare outcomes for patients.

Lead a team of analysts to advance fraud and safety operations through analytics, ensuring robust data products and compliance while empowering stakeholders with actionable insights.

The Director of Software Engineering will lead teams in creating innovative education tech solutions, strategic planning, and optimizing software delivery processes.

Own a product area of the Content Authoring Platform end-to-end: set vision and roadmap, run continuous discovery, define and measure outcomes, partner with engineering and design to deliver features, evaluate and apply AI capabilities prudently, mentor peers, and communicate strategy and trade-offs to stakeholders.

Build and maintain production AI/ML models and pipelines for an NDR platform; develop scalable, secure backend services; optimize detection algorithms and reduce false positives; integrate ML features into product architecture; mentor engineers; participate in code reviews, technical strategy, and documentation; operate cloud-native, containerized services and manage infrastructure as code.

Lead enterprise design and deployment of a global operating model for bovine IVF production. Drive standardization, SPC, automation, AI/analytics, Lean/Six Sigma, quality systems, and continuous improvement to scale consistent, high-throughput production across labs and field operations.