Top Senior Machine Learning Jobs in St. Louis, MO

Leads automated scoring and natural language application research for educational assessment products. Responsibilities include setting team priorities, mentoring scientists, designing and analyzing studies, developing machine learning applications, collaborating with stakeholders, presenting technical findings, writing reports, publishing applied research, and supporting products involving automated scoring, crisis-content detection, and formative feedback.

Leads customer-facing technical delivery from demonstrations and requirements discovery through architecture, implementation, testing, and production launch. Builds AI-driven agents, analytical products, predictive modeling workflows, and data pipelines; integrates solutions with client CRMs, consumer applications, and varied data sources. Partners with client technical teams, presents to senior stakeholders, and feeds field learnings back to the core platform team. Requires occasional travel and strong Python, TypeScript, architecture, cloud, and communication skills.

Design, build, and support high-throughput, low-latency LLM inference and data pipelines; collaborate with data scientists to post-train and evaluate models; implement scalable, production-ready systems with strong testing, monitoring, and performance focus; mentor engineers and iterate on architecture, reliability, and user-facing AI applications.

Supports payer modernization and health services consulting engagements by analyzing operational challenges, optimizing processes, applying business analytics, engaging stakeholders, implementing quality standards, and guiding transformation initiatives. Develops operational support frameworks, conducts market research, manages change, and advises clients on improving service delivery and business performance while mentoring junior team members.

Own the technical sales cycle for Databricks consulting engagements, including discovery, architecture design, solution scoping, estimation, proposals, demos, proofs of concept, workshops, and statements of work. Design lakehouse, data engineering, analytics, governance, security, and AI architectures. Partner with sales, Databricks, alliance, and delivery teams while ensuring effective handoffs into implementation.

The Senior Display Media Account Manager develops and executes digital media strategies, focusing primarily on Amazon DSP, while fostering client relationships, providing analytics, and driving business growth for clients.

Lead GitLab’s company-wide strategy for autonomous, agentic software development workflows. Identify and validate AI opportunities across the SDLC, build prototypes and reference architectures, establish evaluation frameworks and safety controls, and drive internal adoption. Partner across Engineering, Product, Infrastructure, Security, Architecture, and Data and ML teams to scale reliable, observable, compliant agentic capabilities into customer-facing products. Mentor senior technical leaders and represent GitLab externally on AI-assisted development and productivity measurement.

Conducts econometric, causal, statistical, and optimization analyses to improve operational efficiency, resource allocation, product performance, and business outcomes. The role defines efficiency measures, develops forecasting and optimization tools, partners with product and engineering teams on data instrumentation and implementation, and communicates findings to executives through clear reports.

Senior Business Systems Analyst to define requirements for agent-facing servicing applications, design integrations/APIs with core banking systems, translate needs into user stories and acceptance criteria, improve agent workflows and productivity, and identify AI/ML opportunities for fraud detection, automation, and operational analytics. Supports testing, validation, and releases.

Build and deploy mechanistic, hybrid, and data-driven models for pharmaceutical CMC processes, including drug substance, drug product, packaging, labeling, technology transfer, and manufacturing. Integrate process and experimental data into FAIR data products, analytics, dashboards, and AI-enabled tools. Partner with technical teams and CDMOs to support process understanding, forecasting, risk assessment, regulatory filings, and technology-transfer decisions while owning the digital roadmap and mentoring colleagues.

Senior Product Manager responsible for FinCrime product strategy and delivery across fraud prevention, scams, payment risk, vendor integrations, and cryptocurrency-related products. Owns the full product lifecycle, global feature rollouts, stakeholder management, metrics, regulatory alignment, and customer experience. The role requires hands-on experience with fraud analytics, risk and financial modeling, machine learning, AI tools, APIs, payment systems, and financial-services compliance.

Deploys, integrates, and scales enterprise Generative AI solutions across Azure environments. The role develops LangGraph agentic workflows, fine-tunes and evaluates LLMs, reduces hallucinations, integrates retrieval systems and APIs, and collaborates with customer engineering teams. Responsibilities also include requirements documentation, process mapping, automation engineering, software architecture, and communicating business value.

Own and improve Quora’s second-phase ranking models for feed and digest experiences. Build end-to-end machine learning systems covering data pipelines, candidate extraction, feature engineering, model training, and production integration. Identify new product applications for machine learning, develop efficient algorithms with other ML engineers, and contribute methodologies for large-scale recommendation systems.

Leads customer-facing development of AI agent systems, multi-agent workflows, BI and ML pipelines, and enterprise data governance solutions. Partners with Fortune 500 stakeholders to translate business and data challenges into production-grade technical solutions, develops reusable delivery patterns and internal tooling, influences product roadmaps, conducts competitive analysis, and mentors engineers and technical teams.

Build and operate production machine learning systems for Safety AI, including low-latency APIs, data pipelines, model serving, evaluation, monitoring, and rollout infrastructure. Process large-scale camera and telematics data, optimize cloud and edge-to-cloud execution, track model performance and drift, and partner with applied scientists, firmware engineers, platform teams, and product managers to deliver reliable safety features.

Leads eDiscovery and data analysis workstreams for complex cyber incident response matters, overseeing data assessment, review, extraction, normalization, entity resolution, notification, reporting, budgets, vendors, quality, and delivery. Advises legal teams and clients on technical strategies, risks, workflows, and findings. Manages multidisciplinary teams, develops defensible methodologies, mentors staff, resolves escalations, and advances Cyber eDiscovery processes through analytics, automation, and emerging technologies.

Serve as strategic commercial and technology legal advisor, drafting and negotiating software, SaaS, licensing, data, customer, and vendor agreements. Advise on AI products, governance, responsible AI, privacy, intellectual property, regulatory compliance, product launches, and legal risk mitigation. Partner with Sales, Product, Engineering, and executive teams while supporting international and broader legal initiatives. Use legal technology and AI tools to improve legal service delivery.

Drive new enterprise business for Automation Anywhere’s Agentic Process Automation platform. Responsibilities include prospecting, managing sales pipelines, conducting customer presentations and demonstrations, attending industry events, leading proof-of-concept exercises and RFX responses, and coordinating solution design with technical teams. The role requires consultative enterprise software selling, quota attainment, technical communication, and collaboration with sales engineers, partners, and professional services.

Leads strategy, roadmaps, business cases, adoption, and value measurement for enterprise AI products, beginning with AI-driven field-service dispatch optimization. Partners with data science, engineering, operations, finance, marketing, IT, and vendors to deliver measurable business outcomes, manage pilots and rollouts, establish responsible AI practices, and build a scalable AI product function.

Engineer AI-powered threat detections, automated response playbooks, and continuous adversary emulation. Apply machine learning and LLMs to security operations, conduct threat hunting and AI red teaming, map coverage to MITRE ATT&CK, and develop detection-as-code through CI/CD. Build production-grade Python integrations, measurable containment capabilities, and safe autonomous defenses with guardrails. Mentor security professionals and collaborate across threat response, cyber defense engineering, and platform teams.

Founding Product Manager responsible for defining and launching Hightouch’s Agentic Personalization product. The role includes customer discovery, product strategy, agent workflow and approval design, roadmap sequencing, technical decision-making, revenue alignment, competitive positioning, customer calls, and go-to-market collaboration. The PM will work cross-functionally with engineering, design, sales, customer success, founders, and executives to establish product-market fit and scale a new enterprise SaaS offering.

Leads Hightouch’s machine learning organization, including product development, technical roadmapping, recruiting, reliability, and people management. The role focuses on personalization, product recommendations, probabilistic identity resolution, LLM-powered content generation, and scalable machine learning infrastructure for model training and inference.

Develop applied AI research prototypes and systems for agentic marketing applications, focusing on generative image and video, brand asset creation, data workflows, and autonomous evaluation. The role combines probabilistic and quantitative reasoning, backend system architecture, product intuition, experimentation, and customer-focused product development. Responsibilities include building proofs of concept, improving AI-generated media realism and brand alignment, and architecting agentic systems.

Design and launch 0-to-1 AI-powered marketing tools for Hightouch’s Agents product suite. Responsibilities include rapid prototyping, customer research, synthesizing usage data and feedback, shaping product strategy, and collaborating with designers, engineers, and product managers. The role requires strong visual, UI, and interaction design skills, comfort with ambiguity, curiosity about AI, and rapid iteration in a remote-first environment.

Owns multistate U.S. property and casualty insurance product filings from drafting through approval, including AI model documentation, SERFF submissions, objection responses, and regulatory inquiries. The role supports carrier clients, monitors state requirements, develops scalable filing processes, and coordinates with data science, actuarial, product, counsel, regulators, and industry stakeholders. Requires strong technical writing, insurance regulatory expertise, independent judgment, and the ability to translate complex predictive modeling methods into regulator-acceptable documentation.