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Top Senior Data Science Jobs in St. Louis, MO

23 Days AgoSaved
Remote
St. Louis, MO
175K-205K Annually
Senior level
175K-205K Annually
Senior level
Artificial Intelligence • Machine Learning • Software • Analytics
As a Staff Data Scientist, you will develop data-driven fraud prevention solutions using Generative AI, design scalable ML pipelines, and mentor junior data scientists while collaborating across teams to improve analytics and decision-making.
Top Skills: BigQueryDatabricksHugging FaceOpenai ApisPysparkPythonPyTorchScikit-LearnSparkSQLTensorFlowXgboost
23 Days AgoSaved
Remote or Hybrid
St. Louis, MO
190K-232K Annually
Senior level
190K-232K Annually
Senior level
eCommerce
As a Staff Data Scientist for Forecasting, you will develop forecasting algorithms, create data pipelines, mentor team members, and operationalize models for business needs.
Top Skills: MlopsPythonSQL
23 Days AgoSaved
Remote
St. Louis, MO
140K-240K Annually
Senior level
140K-240K Annually
Senior level
Greentech
As a Data Scientist, you will develop predictive models, analyze geoscientific data, and collaborate with geoscientists to improve mineral exploration efforts.
Top Skills: Cloud ComputingGeospatial AnalysisPythonSoftware Engineering
23 Days AgoSaved
Remote
St. Louis, MO
140K-240K Annually
Senior level
140K-240K Annually
Senior level
Greentech
As a Data Scientist, you will build predictive models, develop software tools, and analyze geoscientific data to support mineral exploration and discovery.
Top Skills: Cicd PipelinesCloud ComputingCollaborative Software DevelopmentData Science PackagesGeospatial AnalysesGitMachine LearningPythonVisualizations
Reposted 23 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Artificial Intelligence • Healthtech • Machine Learning
Develop and tune ML models, productionize and deploy strategies for ML systems, and align cross-functionally to communicate performance metrics.
Top Skills: PysparkPythonPyTorchSQL
Reposted 23 Days AgoSaved
Remote
St. Louis, MO
185K-230K Annually
Senior level
185K-230K Annually
Senior level
Fintech • Analytics • Financial Services
The Staff Data Scientist will develop machine learning models, collaborate with cross-functional teams, and use analytics to drive business growth and improve credit risk assessment.
Top Skills: KerasLightgbmPythonPyTorchScikit-LearnSparkmlSQLTensorFlowXgboost
Reposted 23 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Fintech • Financial Services
As an AI-First Data Scientist, you will design and deploy ML solutions, conduct causal analysis, and automate intelligence in decision-making processes. You will work closely with senior operators and business leaders, translating complex problems into data-driven solutions while ensuring model performance and scalability.
Top Skills: Aws SagemakerCloud Ml PlatformsGitJupyterPythonRSQL
Reposted YesterdaySaved
Remote
St. Louis, MO
95K-159K Annually
Senior level
95K-159K Annually
Senior level
Retail • Sports
Lead the design and implementation of AI-driven search algorithms and models. Collaborate with teams to optimize search performance and personalize user experiences. Mentor junior staff and stay updated on latest AI advancements.
Top Skills: Azure DevopsElasticJIRAKafkaLangchainOpenaiPythonPyTorchSolrSparkTensorFlow
Reposted YesterdaySaved
Remote
St. Louis, MO
140K-170K Annually
Senior level
140K-170K Annually
Senior level
Artificial Intelligence • Machine Learning • Software • Analytics
The Senior Data Scientist will design, develop, and own machine learning systems for document verification focusing on computer vision and deep learning. Responsibilities include technical leadership, engaging with customers, and collaborating with engineering and product teams.
Top Skills: CnnsComputer VisionDeep LearningDocument VerificationMachine LearningTransformer-Based Architectures
Reposted YesterdaySaved
Remote
St. Louis, MO
150K-170K Annually
Senior level
150K-170K Annually
Senior level
Biotech
Lead development and operationalization of LLM, agentic, and image AI solutions for diagnostics. Build multimodal datasets, implement RAG and agent workflows, apply ML and statistical methods (DoE, Bayesian optimization, causal/survival/longitudinal), analyze RWE/RWD, and integrate insights across clinical, regulatory, and product teams to drive diagnostic and business impact.
Top Skills: Agentic AiAzureBayesian OptimizationCausal InferenceClaimsConfluenceDatabricksDesign Of ExperimentsDevice Telemetry/LogsImage AiLlmsLongitudinal MethodsModern Ml FrameworksPythonRRegistries)Retrieval-Augmented Generation (Rag)Rwe/Rwd (EhrSharepointSnowflakeSurvival AnalysisVector Databases
Reposted YesterdaySaved
Remote
St. Louis, MO
150K-170K Annually
Senior level
150K-170K Annually
Senior level
Healthtech • Other • Software • Biotech
Lead development and operationalization of LLMs, agentic and image AI solutions; build multimodal datasets; develop production-grade models, RAG pipelines and agent workflows; run RWE analytics and Bayesian optimization for assay/R&D acceleration; deploy solutions on Azure/Snowflake/Databricks and integrate insights into clinical, regulatory, and product programs.
Top Skills: Agent WorkflowsAgentic AiAzureBayesian OptimizationCausal MethodsConfluenceDatabricksDesign Of Experiments (Doe)Image AiLlmsLongitudinal MethodsModern Ml FrameworksPythonRRagSharepointSnowflakeSurvival AnalysisVector Databases
Reposted YesterdaySaved
Remote
St. Louis, MO
150K-170K Annually
Senior level
150K-170K Annually
Senior level
Healthtech
Lead development and operationalization of LLM, agentic, and image AI solutions for diagnostics. Build multimodal datasets, develop production-grade models and RAG/agent pipelines, perform RWE analytics, and integrate insights across clinical, regulatory, R&D, and product teams to drive diagnostic performance and patient impact.
Top Skills: Agentic AiAzureAzure OpenaiClaudeCodexConfluenceDatabricksDelta LakeHugging FaceImage AiLlamaLlmsMistralMlflowPythonRRagSharepointSnowflakeVector DatabasesVs Code
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Reposted YesterdaySaved
Remote
St. Louis, MO
Senior level
Senior level
Artificial Intelligence • Big Data • Information Technology
Design, build, and deploy end-to-end production ML systems for audience targeting, lookalike generation, and propensity scoring. Own ML lifecycle from experimentation to production monitoring, leverage distributed/cloud platforms, implement vector similarity and embedding systems, engineer scalable features, and collaborate with engineering and product teams to ensure model quality and operational reliability.
Top Skills: Aws S3Ci/CdDatabricksFaissGitPythonSnowflakeSparkSQL
Reposted YesterdaySaved
Remote
St. Louis, MO
Senior level
Senior level
Security
The Geospatial Scientist leads data management initiatives, oversees data governance, and ensures quality and compliance of geospatial data for DHS.
Top Skills: Arcgis EnterpriseEsri Geoportal ServerGeoplatform.GovGis Systems
2 Days AgoSaved
Remote
St. Louis, MO
177K-208K Annually
Senior level
177K-208K Annually
Senior level
Real Estate • Travel • PropTech
Drive identity verification initiatives by building AI/ML models to detect fraud, optimize processes, and provide analytical insights for improvements.
Top Skills: AIComputer VisionMlPythonRSQL
Reposted 24 Days AgoSaved
Remote
St. Louis, MO
372K-600K Annually
Senior level
372K-600K Annually
Senior level
News + Entertainment
As a Senior Data Scientist, you'll build machine learning models for infrastructure cost prediction, enhance experimentation methods, and collaborate across teams to improve data quality and impact evaluation.
Top Skills: PythonSQL
Reposted 2 Days AgoSaved
Remote
St. Louis, MO
215K-260K Annually
Senior level
215K-260K Annually
Senior level
Security • Software
Lead Data Scientist responsible for creating ML-driven risk assessments and AI workflows within a SaaS security platform, ensuring effective decision-making and system reliability.
Top Skills: AIMachine LearningStatistical Modeling
2 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Internet of Things
The Senior Data Scientist will lead data analysis for feature areas to drive user growth, create measurement strategies, and deliver insights for product decisions.
Top Skills: PythonSQL
2 Days AgoSaved
Remote
St. Louis, MO
150K-200K Annually
Senior level
150K-200K Annually
Senior level
Internet of Things
The Senior Data Scientist will lead analytical support for Firefox features, providing insights to drive user growth and influence product decisions through statistical modeling and experimentation.
Top Skills: PythonSQL
Reposted 11 Days AgoSaved
In-Office
St. Louis, MO
Senior level
Senior level
Greentech
As a Senior Data Scientist, you will apply machine learning and econometrics to enhance business operations, develop forecasting models, and collaborate with various teams to translate complex data insights for stakeholders.
Top Skills: Azure DevopsPython
2 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Big Data • Analytics • Business Intelligence • Big Data Analytics
The Senior Data Scientist will analyze manufacturing data to improve quality and optimize processes through advanced analytics, with a focus on driving cost and waste reduction.
Top Skills: AIData ScienceMachine Learning
Reposted 2 Days AgoSaved
Remote
St. Louis, MO
145K-170K Annually
Senior level
145K-170K Annually
Senior level
Software • Automation
The Senior Data Scientist at Bluesight will develop machine learning models, collaborate on analytics projects, communicate findings, and elevate the analytics team's skills.
Top Skills: AthenaAWSDockerFastapiFlaskGitGlueMlflowPythonRdsSagemakerSQLTerraform
Reposted 25 Days AgoSaved
Remote
St. Louis, MO
195K-205K Annually
Senior level
195K-205K Annually
Senior level
Fintech • Insurance • Software
Lead development and lifecycle of yield-optimization predictive models, integrate models into the recommendation engine, improve model accuracy to drive revenue and conversion, match users to optimal offers, and manage external partner relationships while collaborating across engineering and business teams.
Top Skills: SQL
3 Days AgoSaved
Remote
St. Louis, MO
50-150 Annually
Senior level
50-150 Annually
Senior level
Marketing Tech • Sales
As a Data Engineer at Common Room, you'll build ETL pipelines, process billions of events daily, and collaborate on backend projects using AWS, Postgres, and Node.js.
Top Skills: ApolloAWSClickhouseExpressKafkaNode.jsPostgresSnowflakeTypegraphqlTypescript
3 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Artificial Intelligence • Big Data • Machine Learning
Seeking a Senior Data Scientist to lead predictive analytics and machine learning initiatives. Responsibilities include building ML models, data management, and mentoring junior data scientists. Must have expertise in AWS and strong statistical knowledge.
Top Skills: AirflowAWSKubeflowNumpyPandasPythonSagemakerScikit-LearnStepfunctionsXgboost
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