Top Senior Data Science Jobs in St. Louis, MO

Reposted 11 Days AgoSaved
In-Office or Remote
St. Louis, MO
56K-196K Annually
Senior level
56K-196K Annually
Senior level
Agency • Information Technology
Build and scale production-ready generative AI applications: design multi-agent workflows, implement advanced RAG with vector DBs, integrate/swap LLMs, fine-tune models, and deploy scalable FastAPI/Docker services with monitoring and optimization for latency, cost, and reliability.
Top Skills: Async PythonCi/CdClaudeDockerFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm Quantization/HostingModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector Databases
Reposted 11 Days AgoSaved
In-Office or Remote
St. Louis, MO
48K-170K Annually
Senior level
48K-170K Annually
Senior level
Agency • Information Technology
Build and scale production Generative AI applications: design multi-agent systems and LangGraph workflows, implement advanced RAG with vector DBs, integrate and fine-tune LLMs, deploy FastAPI async services in Docker, and optimize GenAI performance, cost, and monitoring.
Top Skills: Api SecurityAsync PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLlm QuantizationLocal Model DeploymentModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector DatabasesVector Search
Reposted 11 Days AgoSaved
In-Office or Remote
St. Louis, MO
56K-196K Annually
Senior level
56K-196K Annually
Senior level
Agency • Information Technology
Design, build, and deploy production-ready generative AI applications: architect multi-agent workflows, implement advanced RAG with vector DBs, integrate/swap LLMs, fine-tune models, and deliver scalable FastAPI-based services with monitoring, CI/CD, and containerized deployment.
Top Skills: Async PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector DatabasesVector Search
Reposted 11 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Agency • Information Technology
Design, build, and deploy machine learning and generative AI models (including LLMs and text-to-image). Analyze large datasets, run A/B and statistical tests, collaborate with data engineering and engineering teams, and create dashboards/visualizations to communicate insights. Optimize data pipelines and model performance to support data-driven decisions.
Top Skills: AWSAzureDall-EGCPGeminiGptLlamaLlmsPower BIPythonPyTorchRScikit-LearnSQLTableauTensorFlow
17 Days AgoSaved
Remote
St. Louis, MO
192K-228K Annually
Senior level
192K-228K Annually
Senior level
Healthtech • Social Impact • Software • Telehealth
Owner of analytics for EHR, revenue cycle, and operations: design and run experiments, analyze financial and operational metrics, investigate billing and account issues, and deliver actionable insights to Product, Operations, Finance, and Customer Experience to improve accuracy, reduce friction, and support growth.
Top Skills: EhrHexLookerPythonRevenue Cycle ManagementSQLTableau
Reposted 22 Days AgoSaved
In-Office
St. Louis, MO
160K-190K Annually
Senior level
160K-190K Annually
Senior level
Information Technology • Software • Cybersecurity • Defense
The Data Scientist will create and deliver analytic processes and data solutions while coordinating with clients to address data-related issues. Responsibilities include designing data architecture, building ETL pipelines, integrating APIs, conducting impact analysis, and preprocessing geospatial data.
Top Skills: Cloud ArchitecturesJavaJavaScriptNoSQLPythonSQL
Reposted 13 Days AgoSaved
Remote
St. Louis, MO
170K-220K Annually
Senior level
170K-220K Annually
Senior level
Healthtech • Other • Telehealth
Design, implement, and maintain marketing inference models (e.g., MMM and attribution). Analyze large datasets and A/B/uplift experiments with rigorous statistics, build predictive and causal models, partner with marketing to generate testable ideas, and communicate insights to drive marketing decisions.
Top Skills: PythonRSQL
14 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Software • Consulting • Cybersecurity • Defense
Design, train, fine-tune, deploy, and monitor Large Language Models for government mission applications. Collaborate with cross-functional teams, ensure data preprocessing and model performance, present findings to stakeholders, and mentor junior data scientists.
Top Skills: BertGptLarge Language ModelsNlpPythonPyTorchTensorFlowTransformers
15 Days AgoSaved
Remote or Hybrid
St. Louis, MO
Senior level
Senior level
Software
Lead product experimentation and ML initiatives: design and run A/B tests and causal analyses, build and deploy ML models (GBMs, random forest, logistic regression) using Python and MLflow, partner with Product/Design/Engineering, translate results into executive-facing recommendations, and establish experimentation and ML best practices.
Top Skills: A/B TestingAmplitudeCausal InferenceDatabricksGbmLogistic RegressionMlflowPythonRandom ForestScikit-Learn
15 Days AgoSaved
Remote
St. Louis, MO
185K-231K Annually
Senior level
185K-231K Annually
Senior level
Artificial Intelligence • Software • Analytics • Business Intelligence
Lead and build Neural Earth's geospatial data science function: design and deploy Python-based geospatial models, architect production geospatial data pipelines, validate reproducible methods, translate scientific outputs into customer-ready products, and manage and mentor at least one direct report while advising customers and stakeholders.
Top Skills: CogGdalGeopandasGeoparquetGeotiffNetcdfPythonRasterioShapelyXarray
Reposted 15 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Logistics • Software
Senior individual contributor owning complex end-to-end ML problems for supply chain and consumer applications. Build and deploy predictive models (demand forecasting, delivery ETA, recommendations), embed with engineering teams, define MLOps standards, and advise leadership on data science strategy and investments.
Top Skills: Api EndpointsAWSAzureBigQueryDrift DetectionExperimentation FrameworksGCPGitGitMicroservicesModel VersioningPipeline OrchestrationPostgresPythonSQL
Reposted 15 Days AgoSaved
Remote
St. Louis, MO
150K-195K Annually
Senior level
150K-195K Annually
Senior level
Software • Cryptocurrency • Web3
Partner with Marketing as the embedded data science lead to build marketing measurement, attribution, LTV/ROAS/CAC models, run experiments, analyze the full funnel, create forecasts and dashboards, and influence channel strategy and budget allocation.
Top Skills: Ad PlatformsAppsflyerGoogle AnalyticsLookerMmpPythonRSQLTableau
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Reposted 15 Days AgoSaved
Remote
St. Louis, MO
255K-298K Annually
Senior level
255K-298K Annually
Senior level
Consumer Web • Other • Social Media • Software
As the Staff Data Scientist, you will lead the data science function, driving strategy, mentoring peers, and shaping product direction through advanced analytics and experimentation.
Top Skills: PythonSQL
Reposted 16 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Big Data • Food • Mobile • Payments
Lead company-level measurement and causal strategy, define MAU×ARPU metrics and semantic mart, set scientific standards for experimentation and analysis, own strategic models (MMM, elasticity, forecasting), partner with engineering to productionize analytics, and raise org-wide scientific maturity through governance, templates, and upskilling.
Top Skills: DbtExperimentation PlatformsPythonSnowflakeSQL
Reposted 25 Days AgoSaved
In-Office
St. Louis, MO
Senior level
Senior level
Artificial Intelligence • Cloud • Information Technology • Professional Services
The role involves leading ML project implementations, designing production-grade ML solutions, and optimizing AI applications for clients while ensuring effective communication and project management.
Top Skills: SparkDatabricks Mlops StackDockerGenerative AiMachine LearningMlopsNatural Language Processing
Reposted 21 Days AgoSaved
Easy Apply
Remote
St. Louis, MO
Easy Apply
180K-212K Annually
Senior level
180K-212K Annually
Senior level
Artificial Intelligence • Blockchain • Fintech • Financial Services • Cryptocurrency • NFT • Web3
Own and evolve revenue calibration models tying CX interactions to revenue, design causal inference and experimentation frameworks, build LLM-powered classification/NLP pipelines, productionize models with Analytics Engineers, define segmentation and behavioral signals, and ensure statistical rigor for executive reporting and regulatory defensibility.
Top Skills: A/B TestingCausal InferenceGeminiGenerative AiGleanLibrechatLlmMlNlp
22 Days AgoSaved
In-Office or Remote
St. Louis, MO
124K-165K Annually
Senior level
124K-165K Annually
Senior level
Digital Media • Fintech • Information Technology • Machine Learning • Financial Services • Cybersecurity • Automation
Design, develop, and deploy production-grade generative AI and agentic systems (LLMs, RAG, AI agents). Build document intelligence, retrieval pipelines, vector search, and monitoring frameworks. Collaborate with risk, compliance, product, and engineering to deliver scalable, governed GenAI solutions in regulated environments.
Top Skills: AirflowAWSAws BedrockAzure AiCi/CdDatabricksEmbeddingsHugging FaceLangchainLanggraphMlflowOcrPrompt EngineeringPysparkPythonPyTorchRetrieval-Augmented Generation (Rag)SagemakerScikit-LearnSnowflakeSnowparkSparkSQLTensorFlowVector DatabasesVllm
Reposted 17 Days AgoSaved
Remote
St. Louis, MO
163K-218K Annually
Senior level
163K-218K Annually
Senior level
Internet of Things
The Staff Data Scientist will lead analytical strategies for Firefox, focusing on product growth, measurement frameworks, and mentoring data scientists while guiding data-driven decisions.
Top Skills: PythonSQL
5 Days AgoSaved
In-Office
St. Louis, MO
105K-204K Annually
Senior level
105K-204K Annually
Senior level
Greentech • Hardware • Energy
Develops advanced data science and machine learning solutions using large, structured and unstructured datasets. Responsibilities include data integration, exploratory analysis, predictive modeling, reporting and visualization, algorithm testing, automated analytics, and production model implementation and monitoring. Partners with analysts, engineers, scrum teams, and business stakeholders to deliver measurable value, leads proof-of-concept projects, applies statistical research, and coaches less experienced colleagues.
Top Skills: DatabricksMachine LearningPythonRSASSQL
Reposted 18 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Machine Learning • Software
The Staff Data Scientist will lead the development and deployment of ML and GenAI systems to detect billing errors and fraud in healthcare payments, collaborating with cross-functional teams.
Top Skills: AIData ScienceMachine Learning
Reposted 18 Days AgoSaved
Remote
St. Louis, MO
138K-198K Annually
Senior level
138K-198K Annually
Senior level
Aerospace • Defense
Lead radiometric calibration and image processing for multispectral infrared instruments, commission FireSat satellites, and develop/execute SBEM calibration plans. Implement production-ready pipelines, perform R&D to improve calibration, write production-quality code, and collaborate cross-functionally to maintain operational remote sensing data products and services.
Top Skills: AWSCogNetcdfPythonXarray
Reposted 18 Days AgoSaved
Remote
St. Louis, MO
220K-290K Annually
Senior level
220K-290K Annually
Senior level
Information Technology • Software
Build and productionize ML models and data infrastructure to analyze millions of chaos engineering experiments, detect and explain failures, recommend automated remediation, and integrate AI-driven failure analysis into Gremlin's product using techniques like causal inference, graph ML, time-series modeling, and reinforcement learning.
Top Skills: Agentic AiCausal InferenceChaos EngineeringData PipelinesFeature StoresGraph MlMlopsModel MonitoringModel ServingReinforcement LearningSite Reliability EngineeringTime-Series Modeling
Reposted 5 Days AgoSaved
In-Office
St. Louis, MO
117K-151K Annually
Senior level
117K-151K Annually
Senior level
Insurance
Lead development, validation, deployment, and optimization of predictive models and analytics. Partner with claims, underwriting, actuarial teams to transform complex datasets into actionable insights, ensure data quality and compliance, and communicate results through visualizations. Advance data science capabilities across the organization.
Top Skills: Microsoft Sql ServerPythonPyTorchRScikit-LearnSnowflakeSQLTensorFlowXgboost
Reposted 5 Days AgoSaved
In-Office
St. Louis, MO
Senior level
Senior level
Big Data • Analytics • Business Intelligence • Big Data Analytics
Design, build, validate, and deploy predictive models using Python and SQL. Apply causal inference, A/B testing, matching models, and AutoML to evaluate interventions. Partner with product and engineering to deliver scalable analytics, ensure data quality and model performance, and communicate insights to stakeholders.
Top Skills: A/B TestingAutomlCausal InferenceCausal MlClassificationData EngineeringMachine LearningMatching ModelsPythonRegressionSQLUplift Modeling
Reposted 20 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Cloud • Information Technology • Software • Consulting • Web3
Seeking a skilled Data Scientist/Machine Learning Engineer to develop machine learning models, design AI systems, and collaborate in data analytics. Responsibilities include productionizing models, data engineering, and cross-functional collaboration.
Top Skills: AirflowAWSAzureCi/CdDockerGCPJIRAKubeflowKubernetesMlflowNumpyPandasPlantumlPythonPyTorchSparkTfx
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