Top Senior Data Science Jobs in St. Louis, MO

The Lead Data Scientist will enhance analytics through predictive modeling and data engineering, focusing on quality, feature generation, and continuous learning.

Develop, implement, and maintain ALM and CCAR/PPNR models for balance sheet forecasting. Build customer behavior, prepayment, and deposit models; monitor performance, perform backtesting and sensitivity analysis; collaborate with Model Risk, Market Risk, Treasury, and validation teams; prepare documentation and materials for governance and senior leadership; support balance sheet optimization and regulatory initiatives.

Lead retention and churn efforts by building survival and lifecycle-state models, classifying churn reasons, creating personalized win-back and next-best-action interventions, optimizing offers/promos, designing uplift experiments, and owning production model lifecycle, monitoring, and MLOps across Product, CRM, Marketing, and Engineering.

The Senior Data Scientist leads data-driven initiatives, optimizing analytics for business decisions, mentoring staff, and ensuring data quality across healthcare projects.

The Principal Data Scientist will design, develop, and deploy machine learning models, innovating methodologies and collaborating across teams to enhance financial decision-making and risk management.

Lead development of foundational marketing ML models (customer intent, next-best-action, marketing mix and attribution). Own model selection, explainability, monitoring, decisioning layers, and translate outputs into actionable recommendations for marketing and product stakeholders while providing technical leadership.

Lead development of Vanta's business analytics function: build scalable product data assets, define measurement frameworks, use AI-assisted analytics, partner with cross-functional teams, and deliver executive-level recommendations to drive product and business decisions.

Design, evaluate, and productionize generative AI/ML solutions (RAG, agents, embeddings, retrieval). Build evaluation frameworks for hallucination detection, benchmark LLMs, optimize prompts/models, create datasets, fine-tune models, and collaborate to deploy and monitor enterprise-scale GenAI systems.

Lead end-to-end AI/ML initiatives to improve student retention, engagement, and enrollment. Architect and operate data pipelines, feature stores, and production ML systems; deploy, monitor, and automate models; run experimentation programing and measure business outcomes. Mentor team members and set technical standards across Product, Engineering, and CX.

Lead cross-functional teams to identify and implement revenue-driving strategies. Own revenue optimization, develop quantitative analyses (A/B testing, causal impact), improve data pipelines and tracking, embed AI into workflows, and present insights to leadership to scale and recover revenue.

Consult as a fractional data scientist for hedge funds, private equity firms, and family offices. Lead data science initiatives: build infrastructure, develop and deploy models, create portfolio dashboards, monitor post-deployment performance, and partner with investment teams to turn data into actionable investment insights. Advise on vendor selection, data quality, technology stacks, KPIs, and governance.

Design and evaluate predictive and generative models, extract insights from disparate clinical and product data, build and partner on data pipelines, run rigorous evaluations and experiments, and deliver time-sensitive ad hoc analyses to product, engineering, and clinical stakeholders.

As a Senior Machine Learning Engineer, you'll build and deploy ML models for risk and fraud detection, leading technical efforts and collaborating cross-functionally.

Hands-on senior data scientist splitting work between SQL Server data engineering (ETL, pipeline modernization, data quality) and analytics delivery (Power BI semantic models, dashboards, statistical and predictive modeling). Duties include designing migration options, implementing Python-based cleansing and reproducible analytics, building ETL/deployment processes, responding to ad hoc leadership data requests, and documenting systems for stakeholders. Must obtain VA background/PIV and be a U.S. citizen.

Design, build, and deploy ML models across diverse use cases; work with managed cloud ML platforms and containerized solutions; collaborate with engineers on production integration and MLOps best practices; preprocess and analyze large datasets; mentor teammates and influence technical direction; translate complex ML concepts for technical and non-technical stakeholders.

Lead end-to-end client ML engagements: scope problems, design, build, and deploy production ML solutions across cloud and containerized stacks. Lead and mentor small teams, manage client relationships, evaluate emerging tools, and ensure models are production-ready and explainable to technical and non-technical stakeholders.

As a Lead Data Scientist, you'll design experiments, build predictive models, and lead a team while shaping data-driven strategies to enhance AI deployments.

Design, develop, and deploy time-series and machine-learning forecasting models (ARIMA, SARIMA, ETS, XGBoost, LightGBM) for demand planning, inventory, and sales forecasting. Perform large-scale SQL data processing, operationalize models in cloud environments (Azure preferred), present insights, and lead client workshops.

The role involves building and validating Marketing Mix Models and geo-experiments, managing measurement infrastructure, and communicating insights to stakeholders.

Design and build custom measurement products by combining Nielsen datasets; develop statistical and ML models; write production-quality SQL, Python, and PySpark; build reusable ETL pipelines; use AI tools and design agentic workflows; translate stakeholder requests, document methodology, and collaborate with Research, Sales, and Insights teams.

Design, build, validate, deploy, and monitor machine learning and generative AI solutions for healthcare and life sciences. Work with EHR, claims, and registry data to produce clinical predictions, operational optimizations, and LLM-powered applications. Translate results for stakeholders, document best practices, and mentor client teams.

As a Senior Data Scientist, you'll lead projects leveraging data to enhance healthcare outcomes, mentor team members, and align data efforts with business goals.

The Senior Data Scientist will analyze and optimize marketing funnels, build statistical models, conduct experiments, collaborate with teams, and mentor junior members.

Senior individual contributor who builds statistical models and experiments to optimize acquisition, conversion, retention, and lifetime value. Partners with Product, Marketing, and Engineering to define data requirements, analyze A/B tests, perform cohort and funnel analyses, communicate findings to stakeholders, and mentor junior team members while contributing to analytics best practices.

As a Senior Data Scientist, you will develop statistical models and machine learning algorithms to improve patient enrollment and trial management while ensuring compliance in a healthcare data environment.