Top Python Jobs in San Diego, CA

Build automated end-to-end tests, frameworks, harnesses, services, and infrastructure for autonomous aircraft software across SIL, HIL, and VIL environments. Automate release testing, orchestration, data collection, analysis, and reporting; debug failures across software, networking, hardware, and simulation; expand system coverage; and integrate testing into CI/CD and release workflows.

Build and own the Linux-based edge platform powering factory, deployable, and air-gapped Crucible environments. Responsibilities include system provisioning, networking, security, updates, recovery, device lifecycle management, hardware and peripheral integrations, disconnected operation, fleet management, and full-stack debugging across applications, operating systems, networks, and physical equipment. The role also partners on edge-to-cloud architecture, deployment topology, and system security.

Senior systems administrator responsible for installing, configuring, monitoring, and securing Windows and Linux servers, virtualization, backup/disaster recovery, cloud identity (Azure AD), automation with PowerShell/Bash/Python, endpoint management, and Tier 1/2 support. Mentor junior admins, maintain documentation, support audits and compliance, and participate in incident response and maintenance activities.

Leads the design, development, integration, testing, and qualification of advanced control solutions for high-precision mechatronic systems supporting semiconductor production. Translates product needs into requirements and verification plans, investigates performance issues, manages technical risks, coordinates cross-functional teams and suppliers, and mentors three to five engineers.

Leads interdisciplinary teams developing electronic warfare and mission integration subsystems. Responsibilities include architecture, requirements development and traceability, supplier technical management, risk mitigation, hardware/software integration, trade studies, performance analysis, system testing, and customer coordination. The engineer designs and verifies avionics and EW systems for airborne platforms while producing technical specifications, statements of work, and integration documentation.

Develop and integrate software, avionics, electronic warfare, and multifunction RF subsystems for airborne platforms. Responsibilities include requirements development, functional architecture, interface management, algorithm and performance analysis, supplier coordination, digital simulation, hardware-in-the-loop testing, verification and validation, trade studies, and troubleshooting. The engineer collaborates across hardware, software, firmware, and multidisciplinary teams while documenting designs and integrating mission systems.

Supports the design, development, integration, testing, and validation of embedded software for unmanned aerial and robotic systems. Responsibilities include writing C/C++ software for microcontrollers and real-time systems, debugging hardware integrations, using lab equipment, collaborating with multidisciplinary engineering teams, participating in reviews and documentation, and assisting with prototype, laboratory, and field testing.

Senior technical lead for unmanned systems (UxS) integration and test readiness. Hands-on role integrating autonomy software with aircraft, onboard compute, radios, sensors, and ground equipment; leading platform evaluation, bench and field bring-up, troubleshooting, test execution, readiness criteria, and mentoring cross-functional teams to improve hardware-based autonomy validation and demonstrations.

Lead integration of autonomy software onto diverse platforms by designing and implementing interfaces between autonomy, vehicle subsystems, sensors, payloads, and communications. Configure Linux mission environments, middleware, containers, and deployment pipelines; support SIL/HIL/VIL validation, field tests, demonstrations, troubleshooting, and cross-team coordination while mentoring junior engineers.

Build Blue Origin’s pre-silicon emulation and FPGA prototyping capability from the ground up. Define platform strategy, select hardware, develop build and release flows, and operate nightly image services. Lead FPGA implementation, RTL adaptation, timing closure, hardware-in-the-loop integration, platform debugging, capacity planning, and user support. Collaborate with DSP, RF, antenna, verification, and architecture teams to validate satellite communications hardware and scaled beamforming datapaths.

Owns end-to-end development and support of the Sage 300 ERP ecosystem, including customizations, .NET and Python applications, legacy VB6 maintenance, third-party integrations, SQL Server database design and optimization, reporting, and BI solutions. Collaborates with business and technical stakeholders, contributes to architecture, mentors junior developers, improves processes, documents solutions, and resolves production issues.

Design, architect, develop, integrate, test, and administer embedded real-time software for flight and mission-critical systems. Participate throughout the software development lifecycle, collaborate with multidisciplinary Agile teams, resolve system and programming issues, and deliver software products across multiple baselines. The role requires C, C++, Python, RTOS, multithreaded development, software integration and testing, and an active U.S. Secret clearance.

Develops user-facing applications, dashboards, workflows, visualizations, and analytics tools within Palantir Foundry for Navy mission users. Translates stakeholder requirements into data-driven solutions, working with architects and data engineers on ontologies and pipelines. Responsibilities include writing SQL and Python queries, conducting data analysis, optimizing application performance, supporting testing and deployment, documenting functionality, and participating in Agile ceremonies. The role requires obtaining a Secret clearance and collaborating directly with technical and nontechnical stakeholders.

Architects and implements secure, scalable Palantir Foundry data solutions for Navy mission stakeholders. Designs ontologies, pipelines, workflows, applications, and dashboards; integrates disparate data sources; ensures data quality, lineage, interoperability, cybersecurity compliance, and accreditation. Translates operational needs into technical solutions, guides development teams, documents architectures and estimates, contributes to RFPs, collaborates with vendors, supports AI/ML integration, and mentors junior staff.

Build and maintain Palantir Foundry data pipelines, ontologies, applications, workflows, and decision-support capabilities for defense missions. Translate stakeholder needs into technical architectures, integrate structured and unstructured data, troubleshoot production systems, and support client deployments. Collaborate with engineers, analysts, product owners, and mission stakeholders while applying testing, version control, documentation, and deployment best practices. The role requires client-site travel and eligibility for a Secret clearance.

Develops and tests guidance, navigation, and flight-control algorithms for manned and unmanned aircraft. Responsibilities include designing control laws, modeling aircraft dynamics, integrating software with simulation environments, conducting performance and flying-qualities analyses, supporting hardware-in-the-loop and flight testing, analyzing flight-test data, and preparing technical analyses for design reviews.

Leads embedded software and cryptographic engineering teams developing secure, low-SWaP satellite avionics and payload-processing systems. Oversees software architecture, requirements, implementation, integration, verification, release activities, and development processes for Linux and RTOS products. Manages hiring, mentoring, technical direction, cross-functional collaboration, cybersecurity, reliability, automation, testing, and compliance across aerospace engineering programs.

Develops and maintains automated manufacturing test systems, software, fixtures, interfaces, and test infrastructure for wireless communications products. Partners with engineering and contract manufacturers on design for testability, NPI launches, production deployment, troubleshooting, data analysis, root cause investigation, and continuous improvement. The role supports RF test equipment integration, test coverage, yield, cycle time, documentation, equipment calibration, training, and ISO 9001 compliance. Travel is approximately 15%.

Provide technical support and troubleshooting for autonomous ocean vehicle software; act as customer point of contact; produce integration guides and documentation; debug real-world deployments; assist with payload and feature integrations; collaborate with engineering to reproduce and fix issues; develop and maintain customer-facing Python utilities and tools.

Develop and deliver scalable, distributed SaaS features for a clinical-trial software platform. Responsibilities include architecture and hands-on development, engineering best practices, technology innovation, cross-service and AI-powered feature integration, real-time systems, customer-focused product delivery, and mentoring software engineers. The role collaborates closely with a fast-moving team and contributes to the product roadmap.

Design, implement, and maintain enterprise databases (Oracle, SQL Server, PostgreSQL) for mission-critical Navy LVC environments. Optimize performance, manage backup/recovery, replication, clustering, and high-availability solutions. Implement RMF/STIG-compliant security controls, support ATO/accreditation activities, capacity planning, monitoring, and troubleshooting. Ensure compliance with DoD/Navy cybersecurity policies and support system documentation and remediation.

Develop, deploy, and own mission-critical autonomy software for maritime systems. Work across networking, autonomy, systems integration, and robotics to build, monitor, and troubleshoot deployed solutions, collaborate with customers and multidisciplinary teams, and scale platform capabilities for operational use.

Lead verification of modem PHY IP: define strategies, build block/subsystem verification environments, create testbenches and coverage, correlate RTL with reference models, debug RTL and integration issues, support emulation/FPGA/prototyping and post-silicon debug, and drive regression automation and CI for high-throughput wireless ASIC platforms.

The Flight Navigation Engineer will design, implement, and test navigation systems for uncrewed aircraft and ensure compliance with standards.

The Flight Guidance Engineer will design, implement, and test guidance systems for uncrewed aircraft, integrating them into national airspace systems.