Top Senior Python Jobs in San Diego, CA

Reposted 4 Days AgoSaved
In-Office
San Diego, CA
104K-194K Annually
Senior level
104K-194K Annually
Senior level
Aerospace • Logistics • Security • Software • Cybersecurity
Plan, coordinate, and execute system-level dry-run and formal tests for hardware and software ground and flight release. Develop test strategies, procedures, and requirement-to-test traceability; analyze results; support lab operations and integration testing; apply Agile testing practices; collaborate across systems, software, hardware, cybersecurity, and networking teams; report findings to leadership. Support on-site shifts and moderate international travel for test events.
Top Skills: C++ConfluenceGitIbm Rational ClearquestIbm Rational DoorsJavaJIRALinuxPythonVirtual MachinesWindows
Reposted 4 Days AgoSaved
In-Office
San Diego, CA
139K-242K Annually
Senior level
139K-242K Annually
Senior level
Aerospace • Logistics • Security • Software • Cybersecurity
Lead a 10-20 person software team through full SDLC in an Agile environment. Coordinate with systems, test, DevSecOps, and program leads to deliver real-time/mission-critical embedded software, manage performance metrics, and ensure program and functional objectives are met.
Top Skills: Analog I/OAssemblyAtlassian Tool SuiteCC++Data Distribution Service (Dds)DevsecopsDiscrete I/OEthernet/IpFibre ChannelGreen Hills IntegrityJavaJava MicroservicesJIRAMil-Std-1553NoSQLPythonRealtime LinuxRs-232 SerialSonarqubeSQLUmlWind River Vxworks
Reposted 4 Days AgoSaved
In-Office
San Diego, CA
92K-171K Annually
Senior level
92K-171K Annually
Senior level
Aerospace • Logistics • Security • Software • Cybersecurity
Design and integrate next-generation ground systems for UAVs: define requirements, lead trade studies and subcontractors, develop architectures for classified/unclassified networks, write Python scripts for verification and troubleshooting, and support system integration, deployment, and fielding. On-site in San Diego with up to 25% travel.
Top Skills: AgileCadCatiaIfc UpgradeJIRAPythonTeamcenterUav Command And Control (C2)
Reposted 4 Days AgoSaved
In-Office
San Diego, CA
114K-171K Annually
Senior level
114K-171K Annually
Senior level
Aerospace • Logistics • Security • Software • Cybersecurity
Design, develop, and deliver Java JEE middle-layer enterprise solutions in a SOA environment. Collaborate with systems, cloud, DevSecOps, and test teams in Agile SDLC, implement object-oriented designs, JMS, web services, XML technologies, and participate in integration, testing, and release activities. On-site San Diego role requiring Top Secret clearance and SAP access.
Top Skills: AgileBlack DuckCC++CoverityDevsecopsDockerFortifyGitlabJavaJava Enterprise Edition (Jee)JIRAJmsPythonSdlcSoaTest AutomationWeb ServicesXMLXpathXsdXslt
Reposted 4 Days AgoSaved
In-Office
San Diego, CA
100K-135K Annually
Senior level
100K-135K Annually
Senior level
Aerospace
As an IT Systems Administrator III, you'll manage system infrastructure, enforce security, troubleshoot technical issues, lead IT projects, and mentor junior staff, ensuring compliance and efficient operations.
Top Skills: Active DirectoryAWSAzureHyper-VLinux ServerPowershellPythonVMwareWindows Server
Reposted 4 Days AgoSaved
In-Office
San Diego, CA
136K-201K Annually
Senior level
136K-201K Annually
Senior level
Artificial Intelligence • Automotive • Semiconductor
We are seeking a Timing/STA Engineer with expertise in timing constraints development and STA methodologies for intricate SoC designs. Responsibilities include developing timing constraints, conducting static timing analysis, automating STA processes, and collaborating with cross-functional teams for design optimization.
Top Skills: Eda ToolsPrimetimePythonSta ToolsTcl
Reposted 4 Days AgoSaved
In-Office
San Diego, CA
150K-200K Annually
Senior level
150K-200K Annually
Senior level
Transportation • Travel
As a Senior Electronics Engineer, you'll design and develop reliable hardware systems for autonomous vehicles, balancing speed, reliability, and manufacturability. Responsibilities include electrical design, PCB layout, debugging, and collaborating with cross-functional teams while mentoring junior engineers and analyzing field data for continuous improvement.
Top Skills: Altium DesignerC/C++Python
Reposted 5 Days AgoSaved
In-Office
San Diego, CA
120K-261K Annually
Senior level
120K-261K Annually
Senior level
Software • Quantum Computing • Metaverse • Infrastructure as a Service (IaaS)
Design and automate emulation and simulation models; develop verification environments and test suites for block, chip, and system levels; define verification plans with architects; create tests, assertions, scoreboards, and coverage models; debug testbench and emulation failures; build automation (Makefiles/scripts) and participate in CI, code reviews, and cross-functional collaboration.
Top Skills: CC++EmulationFirmwareFpgaMakefilesPalladiumPerlPythonRubySimulationSystemverilogUvmVerilogZebu
5 Days AgoSaved
In-Office
San Diego, CA
128K-193K Annually
Senior level
128K-193K Annually
Senior level
Energy
Design and analyze aerodynamic systems for Solar gas turbines, including flow paths, turbine airfoils, exhaust diffusers, and collectors. Develop and maintain aerodynamic design methods, software, and analytical tools. Support engine programs, testing, product upgrades, and resolution of durability, manufacturing, and field issues. Collaborate with mechanical design, heat transfer, and performance teams to meet manufacturability, cost, durability, and performance requirements.
Top Skills: Ansys CfxCC++CfdCreoPythonStar-Ccm+
6 Days AgoSaved
In-Office
San Diego, CA
Senior level
Senior level
Information Technology • Consulting
Leads the architecture, deployment, maintenance, troubleshooting, and lifecycle optimization of enterprise SolarWinds Orion monitoring infrastructure. Integrates SolarWinds with Splunk, VMware, Windows Server, Linux, and other technologies; develops documentation and architecture standards; trains operations teams; and serves as the platform subject-matter expert. The role supports national defense missions, requires collaboration with government stakeholders onsite at least two days weekly, and includes occasional OCONUS travel.
Top Skills: AWSAzureGCPHyper-VLinuxPowershellPythonSolarwinds IpamSolarwinds NcmSolarwinds NpmSolarwinds NtaSolarwinds Orion PlatformSolarwinds SamSolarwinds SrmSolarwinds VmanSolarwinds WpmSplunkVMwareWindows Server
6 Days AgoSaved
In-Office
San Diego, CA
172K-258K Annually
Senior level
172K-258K Annually
Senior level
Gaming
Own production operations and support for large-scale AWS and Kubernetes services. Drive production readiness, automation, observability, incident response, performance, capacity, cost optimization, and reliability improvements. Build tools and workflows that reduce operational toil, lead incidents and post-incident reviews, and partner across engineering and product teams. The role requires strong expertise in cloud infrastructure, distributed systems, Linux, networking, CI/CD, infrastructure as code, monitoring, and AI-assisted engineering workflows.
Top Skills: AlbAnsibleApi GatewayAWSBigpandaChefClaudeCloudFormationCloudwatchCodexCursorDatadogDockerDynamoDBEksElasticacheFargateGitGitGoGrafanaJavaJenkinsJIRAKubernetesLambdaMySQLOraclePythonRdsRoute 53ServicenowSlackSnowflakeSpinnakerSplunkSQLTerraformUks
Reposted 6 Days AgoSaved
In-Office
San Diego, CA
Senior level
Senior level
Hardware • Internet of Things
Design and architect digital subsystems for low-power IoT SoCs, implement RTL (SystemVerilog/Verilog), create testbenches and stimulus, manage multi-clock/power domains and timing closure, integrate security features (TrustZone, Secure Boot, PSA L2), and collaborate cross-functionally to deliver silicon to high-volume production.
Top Skills: AhbApbArm TrustzoneAxiEmbedded ProcessorsObiPsa Certified Level 2PythonSecure BootSoc ArchitectureStatic Timing AnalysisSystemverilogTclTiming ClosureUpfVerilog
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Reposted 6 Days AgoSaved
In-Office
San Diego, CA
115K-200K Annually
Senior level
115K-200K Annually
Senior level
Information Technology
Design, implement, and integrate embedded Linux software (applications, servers, drivers). Configure kernels and BSPs, perform feasibility and performance analysis, troubleshoot system-level issues, lead and mentor small engineering teams, define requirements, and manage project execution while collaborating across labs and documenting design alternatives.
Top Skills: Asymmetric Multi-ProcessingBoard Support PackageBootloadersC++CompilersCross-CompilationDebuggersDevice DriversDistributed Revision Control SystemsEmbedded LinuxFreertosLinkersLinux KernelLogic AnalyzerOscilloscopePythonRtosYocto Project
Reposted 6 Days AgoSaved
In-Office
San Diego, CA
165K-175K Annually
Senior level
165K-175K Annually
Senior level
Information Technology • Consulting
Lead Software & AI Engineer responsible for designing, developing, and deploying software solutions integrating AI/ML. Requires extensive experience in cloud-native development and DevSecOps.
Top Skills: AIAWSAzureBashCloud ComputingContainerizationDevsecopsDockerGitlabJavaJenkinsKubernetesLarge Language ModelsLinuxMachine LearningMicroservicesPythonReactSoftware DevelopmentSQLTerraformTypescript
Reposted 6 Days AgoSaved
In-Office
San Diego, CA
140K-150K Annually
Senior level
140K-150K Annually
Senior level
Information Technology • Consulting
The DevSecOps / Systems Engineer will support secure software solutions in DoD settings, deploying, integrating, and managing containerized applications, while automating infrastructure and enhancing CI/CD pipelines.
Top Skills: AnsibleAWSAws CodebuildAzureBashBuildahCentosDevsecopsDockerGitlabHelmJavaJenkinsKubernetesOpenshiftPodmanPowershellPythonReactRed Hat Enterprise LinuxSQLSystems EngineeringTerraformTypescriptUbuntu
Reposted 6 Days AgoSaved
In-Office
San Diego, CA
Senior level
Senior level
Mobile
The role involves designing and simulating RF power amplifiers, with a focus on innovation in CMOS SOI technology for Wi-Fi 7 systems.
Top Skills: CadenceEmxHfssMatlabMomentumPythonRfpro
Reposted 6 Days AgoSaved
In-Office
San Diego, CA
187K-201K Annually
Senior level
187K-201K Annually
Senior level
Artificial Intelligence • Robotics • Software
Lead architecture and re-architecture of HAL, telemetry, and C++ middleware for autonomous mobile robots. Integrate sensors, optimize embedded performance, drive migrations from Python to C++, mentor engineers, and ensure system reliability and observability across the robotics platform.
Top Skills: C++11 (Modern C++)Camera SensorsCmakeEmbedded SystemsGitGoogle TestHardware Abstraction Layer (Hal)ImuIpc / MiddlewareLidarLinux (Ubuntu)MqttPythonTelemetry Systems
Reposted 7 Days AgoSaved
In-Office
San Diego, CA
121K-181K Annually
Senior level
121K-181K Annually
Senior level
Energy
Design, develop, and modernize desktop and web software tools using .NET, databases, and front-end frameworks. Collaborate with cross-functional teams, create technical designs and project plans, implement secure performant solutions, and mentor team members while supporting digital transformation and legacy tool upgrades.
Top Skills: .Net FrameworkAngular (V17+)Api DevelopmentC#DapperEntity FrameworkMiddlewareOraclePythonReactSQLToken-Based Authentication/AuthorizationTypescriptVb.NetWinformsWinuiXaml
7 Days AgoSaved
In-Office or Remote
San Diego, CA
182K-250K Annually
Senior level
182K-250K Annually
Senior level
Big Data • Machine Learning • Software • Analytics • Big Data Analytics
Build and productionize data and AI solutions for federal customers using Databricks. Own architecture, design decisions, data pipelines, ML/AI integrations, and user-facing applications. Lead technical delivery, advise customers, integrate client systems, provide training, and collaborate with engineering, product, support, and project teams. Contribute reusable frameworks and best practices while managing complex stakeholder relationships and delivering secure, scalable production systems.
Top Skills: Ai ApisSparkAWSAzureCi/CdDatabricksGCPJavaScriptMl/Ai ModelsMlopsPythonScalaTypescript
7 Days AgoSaved
In-Office
San Diego, CA
140K-160K Annually
Senior level
140K-160K Annually
Senior level
Aerospace • Defense
Own configuration management for modular aircraft platforms, including engineering change control, baselines, product variants, BOMs, revisions, effectivity, serialization, and as-built records. Administer PLM and CAD data systems, chair the Change Control Board, analyze inventory dispositions, control additive-manufacturing configuration items, and support production, supply chain, quality, payload integration, and customer technical deliverables. Ensure compliance with AS9100, ITAR, and DoD requirements while improving change-process performance.
Top Skills: ArenaCadErpExcelMrpNxPlmPower QueryPythonSolidworksSQLTeamcenter
7 Days AgoSaved
In-Office
San Diego, CA
155K-175K Annually
Senior level
155K-175K Annually
Senior level
Information Technology • Consulting • Cybersecurity • Defense
Develop and integrate software and AI capabilities for Navy expeditionary systems, including sensors, unmanned systems, command-and-control platforms, and Tactical Assault Kit. Build tactical applications, maintain real-time data meshes and pipelines, normalize tactical data, test field systems, and integrate machine learning models. Collaborate with data and systems engineers, troubleshoot operational systems, monitor data reliability, and provide technical guidance for long-term Department of the Navy technology strategies.
Top Skills: AirbyteAmazon S3Apache AirflowApache IcebergApache KafkaArcgisAws KinesisCsvDbtDockerElasticsearchGisGoJavaScriptJSONKubernetesMachine LearningOrcParquetPostgisPostgresPythonRabbitMQReactRedisRustSnowflakeTactical Assault KitXMLZenohZeromq
Reposted 7 Days AgoSaved
In-Office or Remote
San Diego, CA
140K-200K Annually
Senior level
140K-200K Annually
Senior level
Software
The Software Engineer will focus on data collection and managing the ingestion pipeline, collaborating with scientists to enhance model training with high-quality datasets.
Top Skills: BashDockerGCPLinuxPythonTerraform
Reposted 7 Days AgoSaved
In-Office
San Diego, CA
94K-175K Annually
Senior level
94K-175K Annually
Senior level
Aerospace • Logistics • Security • Software • Cybersecurity
Individual contributor Principal/Sr. Principal Systems Engineer supporting aerospace modernization and sustainment. Perform requirements development, interface definition, V&V planning, systems modeling, and integration. Serve Scrum Master duties, coordinate across IPTs, maintain systems engineering artifacts and configuration management, use JIRA for issue tracking, and collaborate with stakeholders and suppliers to execute verification and validation.
Top Skills: Atlassian ToolsCameoCi/CdDoorsDoors DxlJIRAModel-Based Systems Engineering (Mbse)Python
Reposted 8 Days AgoSaved
In-Office
San Diego, CA
175K-235K Annually
Senior level
175K-235K Annually
Senior level
Hardware • Industrial
Lead a team building production perception pipelines (EO/IR, Radar) and a Perception Autonomy service integrating pre-trained ML models. Oversee software development, hardware deployment with verification/validation, cross-team integration, and technical mentoring while delivering robust real-world defense and autonomy systems.
Top Skills: AcousticsAtrC++ClassifierEo/IrFew-Shot ModelsObject DetectionPassive RfPerception AutonomyPerception PipelinesPythonRadarSignal ProcessingSonar
Reposted 8 Days AgoSaved
In-Office
San Diego, CA
92K-171K Annually
Senior level
92K-171K Annually
Senior level
Aerospace • Logistics • Security • Software • Cybersecurity
Support sustainment data analytics for the Triton Enterprise: design data pipelines and models, perform statistical analysis, build dashboards, maintain virtual machines/databases, collaborate across engineering and operations, and mentor teams while ensuring governance, data quality, and applicability of advanced ML methods in defense contexts.
Top Skills: .Dat File DecodingDatabaseMatlabPlotlyPower BIPythonSQLTableauVirtual Machines
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