Top Senior Python Jobs in San Diego, CA

Leads end-to-end development of high-performance mmWave RFIC transmitters for 5G and radar applications. Responsibilities include architecture, circuit and layout design, verification, characterization, RFIC-package-PCB-antenna co-design, production ramp, silicon debug, yield improvement, and technical leadership. The role owns Tx signal-chain performance, mentors engineers, manages technical risks, collaborates cross-functionally, and contributes to technology roadmaps and intellectual property.

The Sr RF/MW Engineer develops and tests RF technologies, performs device characterization, analyzes data, leads projects, and collaborates with teams for wireless chipset solutions.

Leads development, integration, testing, and verification of navigation control systems in an aerospace environment. Responsibilities include managing requirements, specifications, interface control documents, schedules, design reviews, supplier coordination, and technical team collaboration. The role requires MATLAB-based analysis, navigation system expertise, formal program presentations, and familiarity with GPS, inertial sensors, communication interfaces, and anti-jam technologies. This is a full-time, on-site position requiring an active Top Secret clearance and potential SAP access.

Lead the architecture, development, integration, validation, and acceptance of hardware-in-the-loop benches for high-power electronics and precision systems. Build real-time plant and power-electronics models, conduct closed-loop testing, triage defects, and coordinate client sign-off. Direct distributed controls, test, and software teams while managing work breakdowns, reviews, reporting, and access to export-controlled technical data.

Owns propulsion development and integration for small piston engines and microturbojets powering sUAS platforms. Responsibilities include engine selection, fuel and exhaust system design, ECU calibration, test-stand and flight testing, failure investigation, propeller qualification, thermal and electrical integration, documentation, and vendor technical leadership. The role is hands-on at test stands, engine cells, and flight lines, with up to 20% domestic travel.

Owns automation and verification for software subsystems supporting next-generation sequencing instruments. Develops automated test suites, test environments, integration tools, and scalable automation frameworks; contributes to integration strategy and system design; investigates defects; tracks risks and progress; collaborates across functions; and mentors engineers. The role emphasizes software-hardware integration, CI/CD, quality practices, and delivery of release-ready software.

Build and automate secure, mission-critical infrastructure platforms for Department of Defense environments. Develop Puppet modules, Helm charts, GitLab CI/CD pipelines, Bash and Python automation, and reusable infrastructure code for Kubernetes deployments, including disconnected and air-gapped systems. Collaborate with platform and integration teams, ensure STIG compliance, and support customer implementations. The role requires active TS/SCI eligibility, U.S. citizenship, and onsite or hybrid work near San Diego with up to 15% travel.

Design, build, integrate, upgrade, and support enterprise-scale Oracle CPQ and Java-based solutions. Partner with stakeholders, implement integrations and APIs, perform production support, execute upgrades/patches, ensure technical governance, and contribute across the software development lifecycle.

Own production release of a highly integrated mixed-signal SoC from tape-out through qualification, characterization, validation, and volume production. Lead test strategy, ATE correlation, statistical analysis, yield improvement, failure analysis, radiation-mitigation validation, and production-limit setting. Coordinate with design teams, validation and test engineering, OSATs, backend operations, and labs while managing excursions, cost reductions, KPIs, and NPI hardware reviews. Mentor junior engineers and support space-grade digital beamforming ASIC production.

Provides engineering support for communications payload subsystems, including requirements coordination, supplier management, technology assessments, trade studies, system integration, testing, troubleshooting, and performance improvement. Collaborates with program management on schedules, risks, issues, and technical recommendations, while reporting subsystem status to leadership. The position is full-time, on-site in San Diego or Palmdale, requires an active Top Secret clearance, and involves up to 25% travel.

Develop and implement advanced ASICs for aerospace, defense, commercial, and space applications. Responsibilities include physical design, synthesis, timing analysis, EMIR, layout verification, constraints, DFT, formal verification, scripting, and use of EDA tools. The engineer may lead complete design efforts, support advanced technology nodes and radiation-hardened designs, and contribute to post-silicon debug and testing.

Designs GNSS/PNT navigation signals, navigation message formats, simulation tools, and reference implementations for satellite systems. Develops signal-in-space specifications, message encoding, baseband/IQ generation, conformance tests, and golden-reference test vectors. Evaluates acquisition, tracking, bandwidth, synchronization, coding, and receiver performance trade-offs. Collaborates with navigation, timing, RF, FPGA, flight software, payload, and security teams to integrate and verify signal implementations.

Build and maintain CI/CD pipelines, automate infrastructure, and support secure containerized platforms for U.S. Navy mission-planning systems. The role partners with software and cybersecurity engineers to resolve delivery issues, adapt tooling to program needs, and enable rapid microservice deployment to orchestration platforms. Work is hybrid in the San Diego area and requires strong Kubernetes, containerization, infrastructure-as-code, Linux, scripting, and security practices.

Design and maintain C++ and Python software for complex cross-platform systems. Develop APIs, messaging interfaces, CI/CD workflows, and automated tests while integrating distributed real-time systems, simulation tools, and third-party hardware and software. Debug system-level issues involving threading, timing, and data flow, contribute to architecture, and collaborate across teams. The role requires active Secret clearance and supports potential progression to TS/SCI clearance.

Design, develop, integrate, and test safety-critical embedded real-time software for flight/mission systems. Develop automated tests, analyze software requirements, debug hardware/software integration issues, produce technical documentation, and support lab-based Agile development and system-level qualification activities.

Lead the establishment and maturation of the SRE function across cloud infrastructure and platform services. Define reliability targets, build observability, lead incident response and root-cause analysis, improve resilience through automation and testing, and develop operational tooling. Partner with engineering teams on reliability requirements, establish incident practices, mentor engineers, and manage the short- and long-term SRE roadmap.

Architects, develops, and modernizes full-stack containerized applications and microservices. Builds Kubernetes environments, CI/CD pipelines, Helm releases, and DevSecOps security automation. Optimizes relational databases, hardens systems to DISA STIG standards, and mentors engineering teams. Requires strong Linux, Docker, Kubernetes, software architecture, and deployment expertise, plus a Secret clearance or ability to obtain one.

Designs, analyzes, tests, and integrates complex aeronautical hardware and software systems. Responsibilities include systems engineering, trade studies, requirements development, architecture design, interface definition, verification planning, anomaly resolution, technical documentation, and Agile collaboration. The engineer will use MBSE and DOORS, support system integration and testing, communicate technical findings, and work full-time on-site in California with up to 25% travel.

Develop and maintain guidance, navigation, and control methods, tools, and processes for aircraft programs. Design, implement, verify, and test control algorithms, software, simulation tools, and control laws. Build dynamic simulation models and integrate them into software- and hardware-in-the-loop environments. Analyze nonlinear six-degree-of-freedom simulations and support flight testing, proposals, technical planning, cost estimation, and project startup activities.

Design, develop, verify, and test guidance, navigation, and control algorithms, software, simulations, and control laws for air vehicles. Develop linear and nonlinear dynamic models, integrate hardware- and software-in-the-loop simulations, conduct control-system trade studies, support design reviews, analyze flight-test data, and assist with flight-test activities. The role is fully onsite and requires a Secret clearance and eligibility for Special Program Access.

Designs and verifies RF, analog, and mixed-signal integrated circuits from architecture through layout, simulation, silicon characterization, and production release. Responsibilities include transistor-level design, PVT and Monte Carlo analysis, RFIC-package-PCB co-simulation, layout collaboration, laboratory measurements, silicon debug, yield improvement, and cross-functional product validation. The role develops RFIC building blocks including amplifiers, mixers, oscillators, converters, filters, regulators, and calibration circuits.

Develops Model-Based Systems Engineering artifacts, technical requirements, system models, interfaces, specifications, and verification plans. Performs systems analysis, maintains engineering artifacts under configuration management, and coordinates requirements and validation across integrated product teams. The role communicates technical findings to internal stakeholders and external customers while supporting modernization and sustainment efforts. Experience with MBSE, DOORS, Python or scripting, and defense systems is relevant, with Secret and SAP clearance requirements.

Designs and sustains complex classified and unclassified development networks supporting software engineering and test automation. Responsibilities include system architecture, network configuration, hardware and software installation, upgrades, troubleshooting, monitoring, tuning, scripting, security hardening, STIG implementation, documentation, and automation. The role collaborates with engineers, technicians, SMEs, and government personnel, advises on emerging technologies, implements engineering changes, and supports Linux, Windows, virtualization, and containerization platforms.

Build and maintain robotics software for motion and trajectory planning, kinematics, controls, world modeling, device integration, and multi-robot coordination. Develop collision-free plans for physical robotic manipulators, contribute to learning-based methods and simulation, and validate systems through testing. Collaborate with hardware and process engineers, mentor teammates, review code, document systems, and ensure safe, reliable operation on real hardware.

Performs guidance, navigation, and control engineering for unmanned aerial vehicles, including nonlinear 6DOF simulation, MATLAB analysis, embedded flight-control software design and testing, flight-test support, parameter identification, and mission analysis. Develops advanced G&C methods and supports proposals and new projects. The role requires collaboration across disciplines and eligibility for Secret and Special Access Program clearances.