Top Senior Python Jobs in San Diego, CA

Reposted 11 Days AgoSaved
In-Office
San Diego, CA
136K-201K Annually
Senior level
136K-201K Annually
Senior level
Artificial Intelligence • Automotive • Semiconductor
The role involves creating models for analog circuits in Verilog, conducting simulation and verification, and supporting model users. Requires experience in CMOS analog design and Cadence tools.
Top Skills: Cadence VirtuosoPythonSystemverilogVerilog
12 Days AgoSaved
In-Office
San Diego, CA
138K-165K Annually
Senior level
138K-165K Annually
Senior level
Cloud • Healthtech • Information Technology
Design, build, and ship full-stack SaaS features across frontend and backend. Solve moderately complex problems, work within microservices and relational databases, participate in code reviews, mentor junior engineers, and collaborate on cloud-deployed, production-grade services. Focus on quality, user experience, and learning new technologies; exposure to AI-powered features is a plus.
Top Skills: AWSAzureCSSDockerExpressGCPHTMLInversifyMessage QueuesMicrosoft Office Add-In DevelopmentMySQLNode.jsPostgresPostgresPythonReactRedisRestful ServicesTypescriptUvVite
Reposted 12 Days AgoSaved
In-Office
San Diego, CA
177K-266K Annually
Senior level
177K-266K Annually
Senior level
Gaming
The Senior Software Engineer will architect and develop full stack solutions for PlayStation features, focusing on high-quality front-end applications and backend services while collaborating with cross-functional teams and mentoring others.
Top Skills: Android StudioCSSGoHTMLJavaJavaScriptKotlinNode.jsObjective-CPythonReact NativeSpring BootSwiftXcode
Reposted 12 Days AgoSaved
In-Office or Remote
San Diego, CA
168K-210K Annually
Senior level
168K-210K Annually
Senior level
Artificial Intelligence • Software • Biotech
The role involves integrating and operating compute infrastructure for data processing and model inference, ensuring reliability and scalability, and collaborating with ML engineers.
Top Skills: AirflowAWSCoiledDockerKubernetesModalPrefectPython
Reposted 12 Days AgoSaved
In-Office
San Diego, CA
108K-173K Annually
Senior level
108K-173K Annually
Senior level
Software • Semiconductor • Manufacturing
The Design Verification Engineer will create verification plans, develop test cases, and analyze/debug complex digital and mixed-signal circuits using advanced methodologies and tools.
Top Skills: CadenceDesignsyncGitMentor Simulation ToolsPerlPythonSvaSynopsysSystemverilogTclUvm
Reposted 12 Days AgoSaved
In-Office
San Diego, CA
130K-200K Annually
Senior level
130K-200K Annually
Senior level
Internet of Things • Semiconductor
The Sr. Verification Engineer develops verification plans for mixed-signal ICs, mentors junior engineers, and collaborates with various teams. Responsibilities include creating test strategies, implementing testbenches, and supporting silicon validation.
Top Skills: CadencePerlPythonSiemensSynopsysSystemverilogUvmVerilogVhdl
Reposted 13 Days AgoSaved
In-Office
San Diego, CA
140K-220K Annually
Senior level
140K-220K Annually
Senior level
Automotive
Develop and maintain real-time sensor software solutions for autonomous vehicles, integrating AI/ML algorithms for various sensor systems across multiple domains.
Top Skills: AIC++DockerLinuxMlOnnxPythonPyTorchTensorFlow
Reposted 13 Days AgoSaved
In-Office
San Diego, CA
152K-244K Annually
Senior level
152K-244K Annually
Senior level
Healthtech • Biotech • Pharmaceutical
The Technical Lead will build software systems for AI-native drug discovery, design data pipelines, develop APIs, and collaborate with scientists to create efficient workflows and solutions.
Top Skills: AWSAzureC#DockerGCPGoJavaKubernetesMlflowPostgresPythonRedshiftRustSnowflakeSQLTypescript
14 Days AgoSaved
In-Office
San Diego, CA
Senior level
Senior level
Information Technology
Lead Palantir Foundry architecture and ontology design to deliver and sustain operational applications for PSPS, wildfire mitigation, and regulatory reporting. Own implementations from design to production support, develop Workshop apps and pipelines, integrate SAP/OMS/GIS/ERP systems, participate in incident response and readiness exercises, govern ontology lifecycle and platform releases, and mentor junior engineers.
Top Skills: ActionsErpFoundry WorkshopGisJavaOmsOntology ManagerPalantir FoundryPipeline BuilderPythonSAPTypescript
14 Days AgoSaved
In-Office
San Diego, CA
163K-199K Annually
Senior level
163K-199K Annually
Senior level
Real Estate • Financial Services
Design, build, and maintain scalable full-stack applications using Node.js, React, and Python. Develop APIs and microservices, implement IaC (Terraform), manage CI/CD pipelines, optimize cloud infrastructure (Azure preferred), integrate AI-assisted development tools, perform technical leadership, conduct code reviews, and mentor developers to support real estate investment management operations.
Top Skills: Amazon CodewhispererAnsibleAWSAzureAzure DevopsCloudFormationContext ApiCursorDockerEcsExpressGCPGitGithub ActionsGithub CopilotGitlab CiGraphQLJenkinsKubernetesMongoDBNestjsNode.jsOpenai CodexPostgresPythonReactReduxRestful ApiTerraform
14 Days AgoSaved
In-Office
San Diego, CA
163K-199K Annually
Senior level
163K-199K Annually
Senior level
Information Technology • Software
Design, build, and maintain scalable full-stack applications (Node.js, React, Python) and APIs; implement IaC and CI/CD (Terraform, Azure/AWS/GCP); use containerization (Docker, Kubernetes); integrate AI-assisted development tools; provide technical leadership, code reviews, and mentorship; collaborate with product, UX, and business teams to deliver solutions for real estate investment operations.
Top Skills: Amazon CodewhispererAnsibleAWSAzureAzure DevopsCloudFormationContext ApiCursorDockerEcsExpressGCPGitGithub ActionsGithub CopilotGitlab CiGraphQLIacJenkinsKubernetesMcpMongoDBNestjsNode.jsOpenai CodexPostgresPythonRagReactReduxRestful ApiTerraform
Reposted 14 Days AgoSaved
In-Office
San Diego, CA
115K-135K Annually
Senior level
115K-135K Annually
Senior level
Aerospace • Defense
As a Senior RF Electrical Engineer, you will design and integrate antennas and RF systems for sUAS platforms, conducting testing and analysis to ensure performance and compliance with standards.
Top Skills: AwrCstEmi/Emc AnalysisFekoHfssMatlabPythonRf SystemsRf Test Equipment
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Reposted 14 Days AgoSaved
In-Office
San Diego, CA
Senior level
Senior level
Information Technology • Software
The DevOps Engineer will enhance the DevOps culture within agile teams by implementing CI/CD, coaching, and developing quality products across various roles.
Top Skills: AWSCC#C++GitJavaJenkinsPerlPowershellPythonSQL Server
Reposted 14 Days AgoSaved
In-Office
San Diego, CA
Senior level
Senior level
Information Technology • Software
The role requires a Java - Scala Architect to lead data engineering solutions, manage Apache Spark, and work with NoSQL systems while collaborating on data pipelines and processing large datasets.
Top Skills: SparkCassandraClojureCouchbaseGraphxHbaseJavaKafkaMllibNoSQLPythonRabbitMQRedisRest Web ServicesRiakScalaSpark SqlSpark Streaming
Reposted 14 Days AgoSaved
In-Office
San Diego, CA
130K-160K Annually
Senior level
130K-160K Annually
Senior level
Fintech
Responsibilities include designing and managing cloud networking solutions, enterprise infrastructure, security controls, automation scripts, and monitoring tools. Requires strong experience in AWS, Azure, and network security.
Top Skills: AnsibleAWSCiscoCisco IseMerakiAzurePalo AltoPythonSplunkTerraformThousandeyes
Reposted 15 Days AgoSaved
In-Office or Remote
San Diego, CA
120K-166K Annually
Senior level
120K-166K Annually
Senior level
Aerospace • Information Technology • Robotics • Defense
Join ASR as a Senior Software Engineer to maintain and develop swarming algorithms, enhance software architecture, and ensure operational reliability across our robotics systems. Responsibilities include extending the C++ code base and developing Python web services, requiring strong problem-solving skills in complex environments.
Top Skills: AgileC++CSSHTMLJavaJavaScriptKotlinLinuxPosixPython
Reposted 15 Days AgoSaved
In-Office or Remote
San Diego, CA
154K-232K Annually
Senior level
154K-232K Annually
Senior level
Healthtech • Biotech
As a Staff Data Engineer, you will lead in designing, developing, and testing software applications, ensuring quality, scalability, and reliability, while mentoring junior staff and collaborating with teams.
Top Skills: Agile Tools (JiraAvroAWSBig Data File Formats (ParquetConfluence)DatabricksDelta Lake)ETLGitlabPythonRestapiS3ScalaSpark On SnowflakeSQLSqsTableau
Reposted 15 Days AgoSaved
In-Office
San Diego, CA
87K-198K Annually
Senior level
87K-198K Annually
Senior level
Information Technology
As a lead full-stack developer, you'll design, develop, and maintain complex technology systems, coordinate team efforts, and oversee integration within an Agile development environment.
Top Skills: AnsibleAWSDockerHelmKubernetesPythonRed Hat OpenshiftRedhat Enterprise LinuxVMware
Reposted 15 Days AgoSaved
In-Office
San Diego, CA
157K-185K Annually
Senior level
157K-185K Annually
Senior level
Cloud • Healthtech • Information Technology
Lead the development and delivery of scalable software products, ensuring quality and performance while mentoring software engineers and exploring new technologies.
Top Skills: AgnoAWSAzureCSSDockerExpressGCPHTMLInversifyNode.jsPostgresPythonReactRedis CacheTypescriptUvVite
Reposted 15 Days AgoSaved
In-Office or Remote
San Diego, CA
119K-141K Annually
Senior level
119K-141K Annually
Senior level
Cloud • Healthtech • Information Technology
Seeking a Senior QA Automation Engineer to lead automation strategy, develop test frameworks using Playwright and Python, ensuring high-quality software delivery. Responsibilities include test design, defect management, and collaboration in Agile teams.
Top Skills: Ci/CdGitPlaywrightPythonTypescript
16 Days AgoSaved
In-Office
San Diego, CA
120K-228K Annually
Senior level
120K-228K Annually
Senior level
Artificial Intelligence • Consumer Web • Digital Media • Software
Design, implement, and scale event-driven, distributed backend systems in Python on AWS to process and enrich large-scale document and media datasets. Lead technical projects, mentor engineers, integrate ML/LLM components, optimize performance, maintain observability, and collaborate with Data Science, ML Engineering, and Product to deliver reliable high-throughput content processing services.
Top Skills: AirflowAWSCloudwatchDatabricksDatadogEcsElasticacheLambdaLlmMachine LearningPythonScalaSnsSparkSqsTerraform
16 Days AgoSaved
In-Office
San Diego, CA
120K-228K Annually
Senior level
120K-228K Annually
Senior level
Artificial Intelligence • Consumer Web • Digital Media • Software
Lead design and scaling of content ingestion, metadata, and processing systems. Build reliable pipelines handling messy formats, collaborate with ML, security, and product teams, mentor engineers, and drive platform and AI/LLM integration for content workflows and quality.
Top Skills: Aws LambdaAws S3Aws SnsAws SqsAws Step FunctionsGoNoSQLPythonRubySQL
16 Days AgoSaved
In-Office
San Diego, CA
104K-196K Annually
Senior level
104K-196K Annually
Senior level
Artificial Intelligence • Consumer Web • Digital Media • Software
Design, build, and optimize event-driven, distributed backend systems and APIs in Python for large-scale content metadata extraction and enrichment. Deploy and operate resilient AWS-based pipelines, collaborate with ML teams to integrate models, and ensure system performance, observability, and data integrity.
Top Skills: AirflowAws CloudwatchAws EcsAws ElasticacheAws LambdaAws SnsAws SqsDatabricksDatadogLlmMachine LearningPythonScalaSparkTerraform
16 Days AgoSaved
In-Office
San Diego, CA
120K-228K Annually
Senior level
120K-228K Annually
Senior level
Artificial Intelligence • Consumer Web • Digital Media • Software
Design, build, and scale event-driven, distributed backend systems in Python to extract and enrich metadata at massive scale. Lead architecture, mentor engineers, integrate ML/LLM components, optimize performance, and ensure observability and reliability across AWS-based pipelines.
Top Skills: AirflowAws CloudwatchAws EcsAws ElasticacheAws LambdaAws SnsAws SqsDatabricksDatadogLlmMachine LearningPythonScalaSparkTerraform
16 Days AgoSaved
In-Office
San Diego, CA
125K-175K Annually
Senior level
125K-175K Annually
Senior level
Hardware • Semiconductor • Quantum Computing • Manufacturing
Senior mechanical engineering analyst responsible for structural, shock, vibration, adhesive/joint reliability, optomechanics, and thermal/CFD simulations for photonics modules. Mentor junior engineers, perform complex analyses (FEA, transient shock, thermal-mechanical, creep/fatigue, fracture), use CAD and programming tools, and develop engineering practices in a startup environment. U.S. person required for export-controlled access.
Top Skills: Ansys WorkbenchCfdFinite Element Analysis (Fea)MatlabPythonSolidworks
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