Top Senior Python Jobs in San Diego, CA

Develop and lead projects for deterministic, scalable simulation software supporting safety-critical autonomous aviation systems. Responsibilities include improving framework performance, reproducibility, flexibility, flight dynamics modeling, hardware emulation, and simulation-based testing. Collaborate with flight software, guidance, navigation and control, and hardware test teams. Support hardware-in-the-loop, high-fidelity physics simulation, and cloud-based Monte Carlo infrastructure while mentoring team members.

Leads software teams developing, integrating, deploying, and maintaining full-stack mission applications for DoD and intelligence customers. Builds prototypes and high-performance user interfaces, translates operator needs into features, integrates systems, and conducts deployment and field testing in secure operational environments. The role combines customer collaboration, product discovery, engineering leadership, and software delivery in high-security settings.

Designs and maintains infrastructure-as-code foundations for cloud and hybrid environments. Responsibilities include developing reusable Terraform modules, managing state and workspaces, hardening CI/CD pipelines, enforcing policy-as-code, standardizing infrastructure delivery, and troubleshooting large-scale infrastructure. The role requires strong cloud networking, identity, security, scripting, Git workflows, and Terraform expertise, with preferred experience in multi-cloud environments, FinOps, and Terraform ecosystem tools.

Designs and operates observability platforms covering metrics, logging, tracing, dashboards, storage, and alerting. The engineer will manage high-throughput telemetry pipelines, improve signal quality, integrate observability with CI/CD and incident tools, and apply SRE practices including SLOs and error budgets. Responsibilities also include supporting Linux and container platforms, optimizing observability costs, and communicating actionable insights to engineering and business stakeholders.

Reliability Engineer responsible for improving the availability, performance, and operational excellence of large-scale distributed systems. The role involves building automation, operating Linux and Kubernetes environments, managing observability and CI/CD, designing for reliability, leading incident response, and conducting post-incident reviews. Preferred experience includes SLOs, error budgets, chaos engineering, cloud platforms, capacity planning, load testing, and service mesh technologies.

Maintain and improve the reliability, scalability, performance, and operability of ServiceNow’s federal cloud infrastructure. Resolve infrastructure issues, automate repetitive work, develop monitoring solutions, reduce incidents and MTTR, and lead reliability initiatives across hardware, networking, systems, applications, and cloud technologies. This third-shift role supports government customers on a Sunday-Wednesday, 10-hour schedule with no on-call rotation.

Designs, develops, integrates, tests, and administers embedded and real-time software for flight and mission-critical systems. Participates in the full software development lifecycle, including requirements, architecture, implementation, qualification, and delivery. Works in Agile Scrum teams with systems engineering, DevSecOps, cloud, automation, and testing groups. Analyzes system capabilities, resolves software issues, and supports multiple software baselines and real-time operating system environments.

Design, architect, develop, integrate, test, and administer embedded and real-time software for flight- and mission-critical systems. Participate in the full software development lifecycle within Agile Scrum teams, using C++, C, and Python. Collaborate with systems engineering, cloud, test automation, DevSecOps, and systems test teams to resolve software and system issues, support multiple software baselines, and deliver qualified products.

Develops enterprise Java software for payloads and tasking applications in an Agile environment. Responsibilities include object-oriented design, GUI development, microservices, SOA, web services, XML technologies, software integration, testing, and full SDLC participation. The role collaborates with systems engineering, cloud, DevSecOps, test automation, and systems test teams. It requires maintaining a Top Secret clearance and obtaining Special Program Access, with on-site work in San Diego and approximately 10% travel.

Develop, maintain, and execute automated tests for safety-critical embedded and real-time software. Analyze software requirements, perform integration and acceptance testing, diagnose defects, and support qualification activities. Collaborate with systems, hardware, software, and integration engineers across development, laboratory, and operational environments. Create test procedures, technical documentation, integration plans, and software scripts while working within Agile and full SDLC processes.

Develop and maintain software interfaces integrating cameras, radios, sensors, and other payloads with autonomous systems. Build SDK/API integrations, configuration and monitoring tools, mission application extensions, and Docker-based deployments. Debug Linux, networking, hardware, and distributed software systems; contribute production-ready changes upstream; and support field testing, demonstrations, and operational deployments.

The Principal Systems Engineer bridges product support engineering and data science to improve system readiness, supportability, lifecycle costs, and predictive support solutions. Responsibilities include collaborating with technical teams, customers, suppliers, and program management; conducting logistics-focused risk assessments and trade studies; enhancing reliability, maintainability, logistics, and prognostics support elements; validating analytical insights; and presenting recommendations to leadership and external partners.

Design and integrate complex compute subsystems and SoCs, including PCIe, DDR, HBM, UCIe, and Ethernet IP. Develop micro-architecture specifications and RTL, perform design checks, debug issues, and collaborate with verification, performance, backend implementation, and project management teams. Support floor planning, timing closure, design methodologies, and team development while guiding other engineers.

Develops and maintains enterprise engineering toolsets, operational data platforms, mission-critical systems, and CI/CD pipelines. Collaborates across cloud, application, communications, payload, testing, and DevSecOps teams. Responsibilities include predictive analytics, database and container platform development, automation, system deployment, technical risk mitigation, stakeholder communication, and supporting cloud migration and microservices adoption. This is a full-time, on-site role requiring an active Top Secret clearance and eligibility for SCI and SAP clearances.

Lead the architecture and development of core robotics software, including hardware abstraction layers, telemetry, replay systems, and C++ middleware. Integrate sensors and hardware, optimize embedded system performance, migrate Python components to C++, and improve scalability, reliability, testing, and observability. Provide technical leadership and mentorship while collaborating with hardware, autonomy, applications, and QA teams.

Develop and optimize C++ and Python software for autonomous behavior and motion planning. Design trajectory-planning algorithms for single- and multi-agent systems, build testing and simulation tools, diagnose concurrency and performance issues, and validate software on simulated and real hardware. Collaborate across teams on requirements, architecture, flight testing, and product maturation while mentoring engineers and applying advances in robotics and learned planning.

Build and operate developer tools, internal platforms, development environments, project templates, and AI-enabled workflows for Hivemind engineering teams. Improve developer productivity through reusable tooling, paved paths, documentation, adoption efforts, and inner-source practices. Partner with developers to identify friction, measure outcomes using DORA metrics and feedback, and drive technical direction. Staff-level responsibilities include leading cross-team initiatives and shaping organization-wide developer productivity strategy.

Own platform reliability, observability, incident response, scaling, capacity planning, and deployment automation. Monitor system health, debug and resolve incidents, build logging and monitoring tools, improve CI/CD pipelines, develop self-service automation, and strengthen high-availability delivery systems. The role requires clear incident communication, post-incident learning, and collaboration across engineering teams in secure, high-side environments.

Develop and support secure web applications for DoD and regulated environments. Build React and TypeScript interfaces, Python-based REST APIs, PostgreSQL databases, authentication and RBAC systems, and Windows Server deployments. Maintain JSON schemas, troubleshoot software, optimize performance, support offline environments, and document architecture and operational procedures. Collaborate with developers, testers, administrators, subject matter experts, and end users to deliver application features.

Designs, builds, and operates secure, highly available AWS cloud platforms and production workloads. Responsibilities include cloud architecture, infrastructure as code, automation, Kubernetes or ECS operations, CI/CD, security, observability, troubleshooting, cost optimization, and collaboration with application, security, and SRE teams.

As a Sr. Flight Guidance Engineer, you will design, implement, and test guidance systems for uncrewed aircraft, collaborating with operations and pilot teams.

Designs, builds, documents, and administers relational and non-relational database systems supporting mission-critical distributed environments. Responsibilities include replication, high availability, failover, performance tuning, capacity planning, backup and recovery, schema translation, scripting, requirements analysis, and risk assessment. The engineer collaborates within an Agile team with systems, software, test, information assurance, and customer stakeholders. An active TS/SCI clearance with Full Scope Polygraph is required, along with extensive DBA experience and Oracle expertise.

Owns the aircraft fuel system from requirements and architecture through design, procurement, integration, testing, flight, and operational support. Designs and analyzes tanks, pumps, valves, plumbing, venting, sensing, and related hardware across demanding operating conditions. Leads technical reviews, supplier engagement, testing, data analysis, failure investigations, and cross-functional integration for autonomous aircraft systems.

Develops and executes automated integration, installation, acceptance, and qualification tests for embedded software. Responsibilities include analyzing requirements, integrating software components, debugging issues, documenting procedures, submitting problem reports, and collaborating with software, systems, hardware, and test engineering teams. The role supports full software development lifecycle activities in development, laboratory, and operational environments and requires on-site work, travel up to 25%, and an active Top Secret SCI clearance with SAP eligibility.

Designs and develops electrical systems for new products from concept through manufacturing. Responsibilities include system architecture, component selection, schematics, PCB layout, board bring-up, integration testing, verification, bill of materials management, EMC compliance, troubleshooting, and technical documentation. The role collaborates with mechanical, firmware, systems, and software engineers on consumer and medical devices.