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Top Senior Python Jobs in San Diego, CA

Reposted 7 Days AgoSaved
In-Office
San Diego, CA
110K-138K Annually
Senior level
110K-138K Annually
Senior level
Fintech
Lead COE efforts to identify and deliver AI and automation solutions across business units. Conduct process mining, define use cases, produce discovery and design documents, and design secure, compliant architectures integrating platforms like Salesforce, Automation Anywhere, n8n, and Oracle ERP. Drive adoption, measure performance, prioritize initiatives, and pilot emerging technologies to improve efficiency and ROI.
Top Skills: AgentsApi IntegrationAutomation AnywhereBase64DecisionsDocusignEvent-Driven ArchitectureFive9Google Customer EngagementLlmsMicroservicesN8NOracle ErpPower AutomatePythonRagRetoolRpaSalesforceTypescript
Reposted 7 Days AgoSaved
In-Office
San Diego, CA
Senior level
Senior level
Healthtech
Lead and grow multiple AWS-based engineering teams as a player-coach: set technical direction, ensure secure and compliant digital health systems, own delivery outcomes, drive engineering excellence (CI/CD, observability, SLOs), and partner with Product and Security to scale reliable, audit-ready services.
Top Skills: AngularApi GatewayAuroraAws CdkAws LambdaCi/CdCloudFormationCloudfrontCloudwatchDockerDynamoDBEventbridgeGitIamJwtOauth2PythonRdsReactRestS3SnsSqsTerraformTypescript
Reposted 7 Days AgoSaved
In-Office
San Diego, CA
73K-81K Annually
Senior level
73K-81K Annually
Senior level
Fintech • Software • Financial Services
The Senior Infrastructure Engineer will design and operate cloud security frameworks, lead engineering teams, and enhance cloud security posture using automation tools.
Top Skills: AWSAzureBackstageGCPGitHarnessJenkinsKubernetesPythonTerraform
Reposted 7 Days AgoSaved
In-Office
San Diego, CA
150K-225K Annually
Senior level
150K-225K Annually
Senior level
Gaming
The role involves building developer-centric platforms, integrating APIs and service mesh, designing Kubernetes Operators, and enhancing workflows using AI while collaborating across teams to improve developer experience.
Top Skills: Api GatewaysAWSAzureGCPGoKubernetesPythonRustService Mesh
Reposted 7 Days AgoSaved
In-Office
San Diego, CA
183K-274K Annually
Senior level
183K-274K Annually
Senior level
Aerospace • Artificial Intelligence • Machine Learning • Robotics • Software
Design and implement tactical autonomy algorithms for unmanned aircraft, develop software modules, and collaborate with teams for effective integration and testing.
Top Skills: AfsimC++NgtsPythonReal-Time Operating Systems (Rtos)
Reposted 7 Days AgoSaved
In-Office
San Diego, CA
229K-344K Annually
Senior level
229K-344K Annually
Senior level
Aerospace • Artificial Intelligence • Machine Learning • Robotics • Software
Lead and manage teams to develop advanced perception algorithms for unmanned aircraft, focusing on real-time object detection and sensor fusion. Collaborate with cross-functional teams for system integration and validation in various environments.
Top Skills: Eo/Ir CamerasKalman FiltersPythonPyTorchRadarSlamTensorFlow
Reposted 7 Days AgoSaved
In-Office
San Diego, CA
160K-240K Annually
Senior level
160K-240K Annually
Senior level
Aerospace • Artificial Intelligence • Machine Learning • Robotics • Software
Design and develop tactical autonomy algorithms for unmanned aircraft, integrating classical and machine learning methods for defense applications.
Top Skills: AfsimC++NgtsPythonReal-Time Operating Systems
Reposted 8 Days AgoSaved
Easy Apply
In-Office
San Diego, CA
Easy Apply
180K-220K Annually
Senior level
180K-220K Annually
Senior level
Cybersecurity
As a Senior DevOps Engineer, you will design and manage AWS cloud infrastructure, optimize CI/CD pipelines, and ensure system reliability and scalability.
Top Skills: Amazon EventbridgeAmazon KinesisApache KafkaAWSBashCi/CdCloudwatchDockerGrafanaHelmKubernetesPrometheusPythonTerraform
8 Days AgoSaved
In-Office
San Diego, CA
177K-266K Annually
Senior level
177K-266K Annually
Senior level
Gaming
Design and develop scalable, distributed services while collaborating with various teams to support the accounts services platform for SIE.
Top Skills: Aws DynamodbAws Ec2Aws EksAws GlueAws KinesisAws LambdaAws S3Aws SnsAws SqsEnterprise Java/J2EeJaxrsJSONLinuxPythonReactor NettySpringTomcatXML
Reposted 8 Days AgoSaved
In-Office
San Diego, CA
94K-141K Annually
Senior level
94K-141K Annually
Senior level
Hardware • Software • Semiconductor
The Senior Quality Engineer will lead quality analysis and improvement initiatives for semiconductor manufacturing, using data and structured methods to solve problems, enhance reliability, and ensure customer satisfaction.
Top Skills: Iso 9001MinitabPower BIPython
Reposted 8 Days AgoSaved
In-Office
San Diego, CA
100K-120K Hourly
Senior level
100K-120K Hourly
Senior level
Design
The Senior Developer will design, develop, and enhance user-centered digital products, guiding the team and ensuring quality code while collaborating with stakeholders and mentors.
Top Skills: APIsJavaScriptPythonTypescriptWeb Frameworks
Reposted 9 Days AgoSaved
In-Office
San Diego, CA
133K-222K Annually
Senior level
133K-222K Annually
Senior level
Healthtech
Develop and maintain full-stack applications, modernize legacy Java services, and integrate with APIs while ensuring code quality through automated testing.
Top Skills: Amazon Web ServicesCSSGoogle Cloud PlatformHTMLJavaMean StackMongoDBNode.jsPostgresPythonTypescript
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Reposted 9 Days AgoSaved
In-Office
San Diego, CA
Senior level
Senior level
Big Data • Software • App development • Defense • Manufacturing
As a DevSecOps Integration and Support Engineer, you'll manage node deployments, provide customer support, deploy patches, and maintain systems ensuring cybersecurity posture.
Top Skills: AnsibleBashBgpDell Os10DockerKubernetesLinuxOspfPowershellPuppetPythonRedhatTerraform
Reposted 11 Days AgoSaved
In-Office
San Diego, CA
72K-93K Annually
Senior level
72K-93K Annually
Senior level
Fintech • Software • Financial Services
The role involves improving SRE capabilities, ensuring system reliability and availability, and managing cloud deployments and incident management processes.
Top Skills: Cloud Native SolutionsDatadogDynatraceGCPKubernetesPython
Reposted 11 Days AgoSaved
In-Office
San Diego, CA
147K-228K Annually
Senior level
147K-228K Annually
Senior level
Digital Media
Lead the design and optimization of ML systems at Scribd, managing cross-team projects, mentoring engineers, and shaping technical direction for ML initiatives.
Top Skills: AirflowAWSAws SagemakerDatabricksGoGrpcHttp ApisPythonRuby On RailsScalaSparkTerraformWeaviate
Reposted 11 Days AgoSaved
In-Office
San Diego, CA
120K-180K Annually
Senior level
120K-180K Annually
Senior level
Aerospace • Artificial Intelligence • Machine Learning • Robotics • Software
Design and implement automation for build and CI/CD systems, manage build infrastructure, and improve development efficiency through collaboration with cross-functional teams.
Top Skills: AdoBashBazelC++CmakeDockerGitGithub ActionsLinuxPowershellPythonTeamcity
Reposted 11 Days AgoSaved
In-Office
San Diego, CA
174K-261K Annually
Senior level
174K-261K Annually
Senior level
Aerospace • Artificial Intelligence • Machine Learning • Robotics • Software
Lead technical support and integration for AI & Autonomy software in collaboration with customers and the engineering team. Act as a subject matter expert while assisting in pre-sales and post-sales activities, and developing training materials.
Top Skills: C++Python
12 Days AgoSaved
In-Office
San Diego, CA
130K-206K Annually
Senior level
130K-206K Annually
Senior level
Legal Tech
The Solutions Engineer partners with various teams to capture requirements, manage agile backlogs, design solutions, and enhance workflows through iterative improvements.
Top Skills: GoJavaJavaScriptJSONMicrosoft 365Power PlatformPowershellPythonRestSharepointSQLTypescript
12 Days AgoSaved
In-Office
San Diego, CA
150K-220K Annually
Senior level
150K-220K Annually
Senior level
Aerospace • Artificial Intelligence • Machine Learning • Robotics • Software
As a DevOps Engineer, you'll manage CI/CD systems, enhance developer productivity, automate processes, and integrate testing within pipelines, ensuring operational efficiency.
Top Skills: AnsibleAzure DevopsBashDockerGithub ActionsGrafanaJenkinsKubernetesPowershellPrometheusPythonTerraform
12 Days AgoSaved
In-Office
San Diego, CA
120K-145K Annually
Senior level
120K-145K Annually
Senior level
Aerospace
As a Hardware Engineer III, you'll lead the design and development of complex electronic hardware for spacecraft, collaborating across disciplines, mentoring junior engineers, and ensuring mission-critical performance standards in high-speed, analog, digital, and power electronics.
Top Skills: AltiumHyperlynxLinuxOrcadPowershellPythonVhdl
13 Days AgoSaved
In-Office
San Diego, CA
163K-189K Annually
Senior level
163K-189K Annually
Senior level
Information Technology
Design, develop, and maintain scalable backend services and cloud platform components using various technologies while ensuring high code quality and collaborating with teams.
Top Skills: AWSAws CdkCC++JavaScriptNode.jsPostgresPythonReactReact NativeRust
Reposted 13 Days AgoSaved
In-Office
San Diego, CA
141K-229K Annually
Senior level
141K-229K Annually
Senior level
Healthtech • Biotech • Pharmaceutical
Design and develop software for automated laboratory workflows, build data pipelines, implement machine learning models, and integrate various systems to enhance biotherapeutics discovery.
Top Skills: AWSAzureBashC#C++GitGitlabJavaScriptJmpMatlabPower BIPythonRSASSpotfireSQLTableauVBA
Reposted 13 Days AgoSaved
In-Office or Remote
San Diego, CA
130K-195K Annually
Senior level
130K-195K Annually
Senior level
Information Technology • Legal Tech
The Senior Datacenter and Cloud Engineer manages datacenters, analyzes system performance, and collaborates with teams on infrastructure projects, ensuring optimal functionality.
Top Skills: AWSAzureCisco UcsCohesityImanageMS OfficePowershellPythonVeeamVMware
Reposted 13 Days AgoSaved
In-Office
San Diego, CA
119K-179K Annually
Senior level
119K-179K Annually
Senior level
Semiconductor • Manufacturing
The Senior Engineer in Photonic Design & Testing will design, develop, and test advanced photonic systems and algorithms, while collaborating with various engineering teams to enhance sensor capabilities.
Top Skills: 3D PrintingDeep LearningFdtdFemLabviewLightoolsMachine LearningMatlabPythonPyTorchTensorFlowZemax
Reposted 13 Days AgoSaved
Easy Apply
In-Office
San Diego, CA
Easy Apply
198K-233K Annually
Senior level
198K-233K Annually
Senior level
Artificial Intelligence • Information Technology • Machine Learning • Marketing Tech • Software • Biotech • Design
As a Staff FEA Engineer, you will develop and validate FEA models, perform structural analyses, optimize designs, and collaborate with engineers to enhance wearable device performance and reliability.
Top Skills: AbaqusAnsysPython
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