Top Software Engineer Jobs in Buffalo, NY

Provides hands-on technical leadership across product areas by defining architecture, engineering standards, and scalable system designs. Leads modernization, cloud transformation, platform scalability, developer productivity, and cross-team technical initiatives. Partners with product and engineering stakeholders, conducts design reviews, manages technical risks, and mentors engineers. Requires extensive experience with TypeScript, Node.js, C#, distributed systems, cloud platforms, DevOps, Terraform, and reliable enterprise software.

Leads the Bioinformatics Software Engineering team and owns engineering strategy, architecture, delivery, modernization, and production support for clinical genomics platforms. Oversees software engineers, bioinformatics workflows, data integration, automation, quality systems, release governance, reliability, and regulatory compliance. Partners with clinical, laboratory, scientific, quality, product, operations, and executive stakeholders to convert research methods into validated production workflows. Guides AI-enabled engineering initiatives while ensuring privacy, traceability, clinical-grade quality, and operational resilience.

The Staff Software Engineer will shape technical direction, build developer platforms, and design AI agents, enhancing developer productivity and collaboration across teams.

As a Senior Software Engineer, you will design and build a cutting-edge identity search platform and implement AI systems for defense applications, working closely with cross-functional teams to enhance user workflows and support national security.

The Staff Software Engineer will lead technical strategy, ensure system availability, and develop backend systems at scale, collaborating across teams to drive capacity modeling and operational quality.

As a Senior Software Engineer, you will design and maintain systems, mentor team members, and improve both code quality and team practices.

Lead cross-pod technical direction and system design for high-scale backend services, embed AI-native development practices, collaborate with product and design, mentor engineers, and drive ambiguous initiatives from design through production.

Lead development and reliability of real-time and batch payment-processing systems across authorization, clearing, settlement, disputes, and card-network integrations. Build scalable, secure, low-latency services using Java, Python, Kotlin, and AWS; improve network peering infrastructure, failover, and capacity. Own initiatives from planning through launch, participate in on-call rotations, reduce technical debt, and drive cross-functional engineering improvements and strategic planning.

Own and develop Curri’s React Native driver applications across iOS and Android. Lead mobile features from problem definition through deployment and measurement, build offline-first capabilities, background geolocation, and push notifications, and debug native modules and production issues. Collaborate directly with drivers, operations, Product, and Design while contributing to full-stack work and AI-assisted development.

Lead development of decision logic engines and regulatory consultation workflows for a federal Endangered Species Act platform. Implement species routing, agency-specific templates, REST integrations, testing, defect resolution, documentation, and approved updates. Maintain code review and version-control standards while supporting government acceptance and production feedback.

Lead architecture updates and REST API integration for a federal environmental consultation platform. Implement cloud data integration, species display functionality, consultation logic, interoperability fixes, demo environment support, production deployments, and operational documentation. The role requires backend development, federal application integration, accessibility compliance, Git-based development, FedRAMP deployment knowledge, and the ability to obtain Public Trust clearance.

Build and maintain backend computation engines for solar and electrical design. Develop simulation and optimization systems for PV and battery storage layouts, component selection, and electrical configuration. Translate physical models into reliable, scalable software, shape computation infrastructure, write tested code, mentor teammates, collaborate cross-functionally, and own services through production and on-call support.

Modernize and maintain a large-scale React Native mobile app with offline-first architecture, BLE device integrations, data synchronization, and performance improvements. Influence architecture, mentor developers, collaborate across teams, and occasionally visit customer farms to understand workflows.

Build full-stack features and infrastructure analytics products to improve Netflix's cloud and AI efficiency. Design frontends (React/TypeScript), backend services/APIs (GraphQL/Node), shape data models, collaborate with analytics and data engineers, and own product direction from design through implementation.

Modernize and evolve a large-scale React Native mobile app with offline-first architecture, BLE device integrations, local data storage and sync. Improve performance, reliability, and scalability, influence architecture, mentor developers, collaborate cross-functionally, and occasionally visit farms to understand user workflows.

Designs and maintains Java and Spring Boot microservices for a secure, cloud-native foundation platform. Builds authentication and identity integrations using SAML, OAuth 2.0, OIDC, JWT, and RBAC; develops AWS infrastructure and resilient distributed systems; supports CI/CD, production operations, and on-call response. Provides technical leadership through architecture, code reviews, mentoring, and cross-functional collaboration while maintaining compliance with confidentiality, HIPAA, and regulatory requirements.

Own HUD’s production infrastructure and backend platform systems, focusing on reliability, scalability, performance, cost, deployment safety, and developer experience. Build AWS infrastructure with Terraform and Kubernetes, improve CI/CD and observability, design resilient services and asynchronous systems, manage incidents, and develop internal automation and tooling. The role supports high-availability AI, marketplace, and data-heavy workloads.

Develop and launch scalable web and mobile healthcare applications, APIs, integrations, and cloud infrastructure. Contribute to the technical roadmap, observability, security, compliance, and AI/ML infrastructure. Partner with the founding team and data science leadership to incorporate LLMs, support HIPAA and SOC 2 requirements, and build reliable products for patients and enterprise healthcare customers.

Leads development of scalable backend systems and applications for the Mindbody ecosystem. Responsibilities include designing APIs and microservices, owning complex technical projects, collaborating with Product, Design, and QA, promoting engineering best practices, mentoring engineers, conducting code reviews and interviews, and leading incident postmortems. The role requires strong software architecture experience, large-scale SaaS development, cloud and database expertise, and effective cross-functional leadership.

Develop high-quality, resilient software across Ubuntu and the open source stack, from Linux systems and firmware to cloud, containers, and desktop applications. Contribute to product roadmaps, user experience, code reviews, issue resolution, security, and enterprise requirements. Collaborate remotely with global engineering teams and the open source community, while building expertise in programming languages and Linux systems. Attend international company sprints twice yearly.

Principal frontend-focused software engineer responsible for leading frontend architecture, standards, tooling, accessibility, performance, testing, and deployment practices. The role delivers scalable customer-facing web applications, component libraries, and design systems using React or Angular. It includes cross-functional product collaboration, technical decision-making, mentoring, modernization initiatives, and occasional full-stack work. The position is remote, requires U.S. citizenship, Public Trust 6C eligibility, and approximately 0–10% business travel.

Senior Software Engineer responsible for compliance validation, defect remediation, production migration support, monitoring, and operational documentation for a federal ESA Section 7 data integration platform. The role validates decision logic and consultation routing, develops migration runbooks and rollback procedures, resolves critical application defects, supports post-deployment operations, incorporates user feedback, and enforces code review and version control practices.

Designs, builds, and optimizes CI/CD pipelines across legacy mainframe and AWS environments. Automates workloads, integrates testing, maintains APIs, supports application integration, troubleshoots deployment issues, and improves DevOps processes. The role also supports software developers in an Agile/Scrum environment and contributes to modernization efforts bridging z/OS systems with cloud platforms.

Lead design and build of production-ready cloud and AI systems, prioritize security and reliability, ship solutions quickly using modern engineering practices, collaborate with cross-functional teams, mentor engineers, drive customer adoption, and deliver reusable assets and end-to-end complex deliveries.

Design, build, and scale highly available backend and frontend systems powering Coinbase trading experiences for millions of users. Architect extensible support for multiple trading types and assets, evolve critical production infrastructure, partner with product and design, and promote engineering quality through code reviews, mentorship, and knowledge sharing.