Top Senior Machine Learning Jobs in Buffalo, NY

Lead end-to-end enterprise customer engagements and onboarding for large insurance clients, run program timelines and executive reporting, design and deploy AI agents and internal tooling, own the CE operations roadmap and knowledge base, drive cross-functional resolution of technical/operational issues, and continuously improve efficiency and quality across the Client Engagement team.

Lead product strategy and execution for data and AI platforms, driving GenAI/LLM initiatives, cross-functional collaboration, responsible AI governance, experimentation (A/B testing), measurement of model impact, and mentoring product teams to embed scalable ML capabilities into clinical and member experiences.

Design, build, and scale backend systems and APIs for high-transaction consumer products. Collaborate with product, credit, compliance, support, and analytics teams. Contribute to code reviews, technical planning, security, and operational excellence. Mentor peers and promote engineering best practices.

Lead the development and implementation of machine learning solutions, managing a team to drive strategic decisions and innovative business outcomes.

Design, implement, and scale ML-based solutions for search and advertising; define data collection, evaluation, and production serving strategies; analyze data to inform development; communicate cross-functionally; produce technical reports; and stay current with advances in LLMs, vision models, and generative AI.

Industry Expert who reviews and defends advanced AI/ML and systems engineering projects, chairs architecture and executive review panels, hosts occasional technical sessions, and sets standards for instructors. The role requires production-scale engineering experience, live architecture critique, a public technical footprint, strong English, and expertise in agentic systems, LLM evaluation, model serving, cloud infrastructure, distributed systems, observability, RAG, and enterprise deployments.

Build and deploy LLM-powered agents, workflows, and production integrations using platform templates, pipelines, and guardrails. Develop and run evaluation suites, integrate business systems and data sources, instrument cost and quality telemetry, and collaborate with business users to iterate within bounded scopes. The role requires strong Python and TypeScript, API development, prompt and context engineering, and production experience with agents, RAG, and tool use.

Build and deploy LLM-powered agents and workflows using templates, pipelines, and guardrails. Develop comprehensive evaluations, integrate AI solutions with business systems and data sources, and instrument applications for cost and quality telemetry. Collaborate with business users to iterate within defined scopes. The role requires strong Python and TypeScript skills, production experience with LLM applications, API development, prompt and context engineering, retrieval, and healthcare data handling.

Build and operate production machine learning systems for Airbnb Payments, including LLM agents, real-time fraud detection, anomaly detection, personalization, and checkout optimization. Design, train, deploy, monitor, and continuously improve batch and streaming AI applications at global scale. Partner with product, engineering, operations, and data science teams, establish model governance and testing standards, and mentor engineers.

Lead development of new credit line management programs by designing, testing, and scaling policies. Own end-to-end analytical work using SQL/Python, partner with Data Science and Product, and present data-driven recommendations to senior stakeholders to improve spend recovery, utilization, and line-management performance.

Lead the integration of AI and digital solutions in manufacturing processes, driving adoption and measurable impact on efficiency, quality, and performance.

As a Senior Machine Learning Engineer, you will enhance diffusion models, conduct research, collaborate on system implementations, and communicate findings effectively.

The Principal Product Manager - Growth will lead growth initiatives, focusing on user engagement, retention, and the use of AI to enhance product strategies and experiences.

Design, build, and deploy machine learning systems for controlling quantum processors. Develop reinforcement learning and Bayesian methods for QEC calibration, and work cross-functionally with product and R&D teams.

The Senior Technical Architect will lead AI SDLC transformations, create architectural solutions, mentor teams, and drive innovation in regulated industries.

As a Regional Sales Director, you'll lead a sales team, develop business plans, and drive sales growth by managing complex cycles and nurturing talent.

Own the full lifecycle of clinical text extraction models, from problem framing and annotation strategy through production deployment, evaluation, monitoring, and retraining. Build clinical NLP pipelines, establish defensible quality and error-analysis systems, and apply LLMs using rigorous evaluation, observability, and cost controls. Partner with clinical data and backend engineering teams while addressing PHI protection, de-identification, auditability, and access controls. As the first ML hire, set technical direction and potentially build and lead the future ML team.

Lead end-to-end product strategy and delivery for a core marketplace area, collaborating with engineering, UX, and design. Conduct qualitative and quantitative research, run agile sprints, measure results with analytics, and pioneer AI/ML product features and workflows to improve user experience and platform impact.

Lead go-to-market for Mapboxs AI products: define positioning, messaging, and launch strategy; drive customer research, sales enablement, content, and cross-functional alignment to accelerate adoption of AI-powered location capabilities.

Lead development and application of analytics, statistical models, and dashboards to support R&D Quality oversight. Integrate clinical, safety, lab, and operational data to identify risks, support audit/inspection readiness, enable RBQM, and provide actionable quality insights and recommendations to cross-functional partners.

Lead strategic vision and execution of next-generation bioinformatics technologies. Identify and evaluate emerging computational methods, translate research into production-grade pipelines and prototypes, support product roadmaps and technology transfer, and partner cross-functionally to commercialize genomic and AI-driven healthcare solutions.

Lead combined Analytics Engineering and Data Engineering teams owning the end-to-end data roadmap from ingestion to trusted metrics. Manage hiring and performance, set architecture and platform investments, enforce testing/monitoring/documentation standards, review technical decisions, and partner with product and business stakeholders to translate needs into prioritized deliverables.

Provide senior legal and regulatory counsel for digital health and medical device products (SaMD), guiding product lifecycle, FDA and global filings, AI-enabled features, labeling, compliance, post-market obligations, and cross-functional governance. Lead strategy, manage external counsel, and translate regulatory developments into business guidance.

Develop and scale machine learning training systems for robotics data, optimize training pipelines, and collaborate with ML researchers to enhance autonomy models.

Lead design, development, and production deployment of ML and algorithmic solutions. Own end-to-end ML systems, support distributed production reliability, communicate tradeoffs, and apply generative AI, LLM fine-tuning, RAG, and agentic techniques to product problems.