Top Senior Project Manager Jobs in St. Louis, MO

25 Days AgoSaved
Remote
St. Louis, MO
40-55 Hourly
Senior level
40-55 Hourly
Senior level
Fitness • Software
Contract Project Manager to lead end-to-end operational initiatives across internal teams and external partners, drive cross-functional alignment, build project plans and dashboards, mitigate risks, and establish durable PM processes and executive reporting during a 9–12 month 1099 engagement.
Top Skills: AsanaExcelJIRASmartsheet
2 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Artificial Intelligence • Enterprise Web • Software
Manages end-to-end implementation of technical software projects for government agency clients. Responsibilities include developing work plans, assigning resources, managing scope, reviewing deliverables, tracking budgets and profitability, mitigating risk, maintaining documentation, leading cross-functional teams, and managing client expectations. The role facilitates meetings, communicates project status, resolves issues, and supports successful customer engagements. This is a remote position with travel of up to 30%.
Top Skills: Cloud ComputingDatabasesSystem Design
Reposted 2 Days AgoSaved
Remote
St. Louis, MO
100K-100K Annually
Senior level
100K-100K Annually
Senior level
Information Technology
Lead multiple technology implementation projects to deliver on time and on budget. Coordinate stakeholders, vendors, and technical teams; manage scope, schedule, budget, resources, and change control; ensure SOW deliverables and quality. Oversee day-to-day project phases, timesheets/expenses, and client relationships. Support process improvement, maintain PM certifications, and participate in program/project management practice development.
Top Skills: Microsoft Project
Reposted 2 Days AgoSaved
In-Office or Remote
St. Louis, MO
Senior level
Senior level
Hardware • Other • Software • Appliances • Industrial • Manufacturing
Lead end-to-end healthcare SaaS implementations of CensiTrac, managing project plans, scope, change, risks, cross-functional teams, KPIs (CSAT, revenue, velocity), stakeholder communication, process improvements, and transitions to support.
Top Skills: Ai Productivity ToolsCensitracProject Management SoftwareSalesforce
Reposted 25 Days AgoSaved
Remote
St. Louis, MO
8-12 Annually
Senior level
8-12 Annually
Senior level
Information Technology • Consulting
Manage client project plans and budgets, ensuring alignment with client requirements, while leading Agile ceremonies and promoting best practices. Requires technical knowledge and project management skills to address challenges and enhance collaboration.
Top Skills: JavaJIRAMs ProjectTrello
Reposted 3 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Healthtech
The Senior IT Project Manager oversees the delivery of technology and business transformation projects, supports PMO standards, manages project risks, and mentors junior managers.
Top Skills: JIRAMs ProjectServicenow PpmSmartsheet
Reposted 3 Days AgoSaved
Remote
St. Louis, MO
140K-185K Annually
Senior level
140K-185K Annually
Senior level
Biotech
Manage biomarker operational work for clinical trials, oversee junior project managers, and collaborate with internal and external stakeholders to ensure project success.
Top Skills: MS Office
Reposted 3 Days AgoSaved
Remote
St. Louis, MO
155K-175K Annually
Senior level
155K-175K Annually
Senior level
Fintech
Lead as a technical operator between product, engineering, design, and leadership to remove blockers, accelerate delivery, and compress feedback loops. Drive rapid prototyping-to-production cycles, introduce AI tooling and lightweight processes, directly contribute to delivery, surface risks and dependencies, and scale team workflows so the product organization ships higher-quality features faster.
Top Skills: ClaudeCursorV0
Reposted 3 Days AgoSaved
Remote
St. Louis, MO
90K-105K Annually
Senior level
90K-105K Annually
Senior level
AdTech
The Senior Operational Project Manager coordinates delivery across multiple departments, manages client engagements, oversees resource allocation, and ensures project timelines are met within a fast-paced marketing agency environment.
Top Skills: Adobe Creative SuiteCapcutFigmaFrame.IoGoogle SuiteHubspotJIRAKantataMonday.ComSlackTimelyZiflow
Reposted 3 Days AgoSaved
Remote
St. Louis, MO
84K-126K Annually
Senior level
84K-126K Annually
Senior level
Information Technology
Lead complex federal technology and digital services projects from discovery through deployment. Manage scope, schedule, budget, risks, and resources; facilitate Agile delivery; partner with technical leads; maintain project financials and reporting; serve as primary client contact and drive team collaboration and CPARS performance. Position contingent on contract award.
Top Skills: AgileCloudCmsScrumWeb
Reposted 3 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Information Technology
Lead delivery for a complex telecom transformation: translate technical designs into delivery plans, coordinate architects/engineers/vendors, manage risks/dependencies, maintain schedules and financials, drive cross-functional collaboration, and support transition to operations.
Top Skills: Azure DevopsJIRAMicrosoft ProjectSmartsheet
Reposted 3 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Software • Consulting
Lead end-to-end delivery of complex technology projects using formal PM frameworks and Agile/Scrum. Establish governance, integrated plans, risk management, executive reporting, cross-functional alignment, vendor management, and transition to operations. Facilitate Scrum ceremonies and governance forums, drive accountability, and ensure projects deliver agreed strategy and value.
Top Skills: AgileAsanaConfluenceJIRAKpi/Csf TrackingMonday.ComScrum
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Reposted 3 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Software
The Technical Project Manager will oversee R&D Cloud initiatives, manage project scope, timeline, and budget, and ensure cross-functional collaboration to deliver innovative solutions.
Top Skills: AsanaCloudMs ProjectSmartsheet
Reposted 3 Days AgoSaved
Remote
St. Louis, MO
94K-135K Annually
Senior level
94K-135K Annually
Senior level
Consulting
Lead multiple complex, client-facing projects for state health and human services programs (Medicaid, SNAP). Manage schedules, budgets, contract compliance, cross-functional teams, sprint priorities, testing, proposals, training, and provide client support and travel as required.
Top Skills: Microsoft AccessExcelMicrosoft PowerpointMicrosoft Word
Reposted 4 Days AgoSaved
Remote or Hybrid
St. Louis, MO
50-64 Hourly
Senior level
50-64 Hourly
Senior level
Cloud • Information Technology
Translate business requirements into PEGA Decisioning solutions, manage project scope end-to-end, create and maintain decisioning logic and documentation, execute UAT and regression testing, liaise between Marketing and Technology, and present status to senior management.
Top Skills: AdobeAPIsAsanaClarifyJIRAMs PowerpointOraclePegaPega CdhPega DecisioningPega Prediction StudioSalesforceSASServicenowSharepointSQLUnicaXML
Reposted 4 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Artificial Intelligence • Healthtech • Biotech
Lead technical project planning and execution across software and neurotech research. Translate company goals into actionable plans, run sprint planning and retrospectives, remove bottlenecks, design scalable processes, support strategic prioritization, mentor team members, and ensure cross-disciplinary teams deliver high-quality, rapid iterations.
14 Days AgoSaved
Hybrid
St. Louis, MO
Senior level
Senior level
Consulting
Lead and oversee consulting, design, or construction management for large, complex life-sciences and food & beverage projects. Manage client relationships, large teams, subcontractors, project delivery, and ensure successful execution under ONEsolution methodology.
4 Days AgoSaved
In-Office or Remote
St. Louis, MO
36K-128K Annually
Senior level
36K-128K Annually
Senior level
Agency • Information Technology
Lead planning, execution, and delivery of enterprise technology projects. Manage scope, timelines, budgets, resources, risks, vendors, and stakeholder communications across Agile, Scrum, and Waterfall environments. Oversee software development, technology implementations, cloud transformation, application modernization, and other enterprise initiatives while coordinating cross-functional teams and multiple concurrent priorities.
Top Skills: AgileApplication ModernizationCloud TransformationScrumSdlcWaterfall
Reposted 4 Days AgoSaved
In-Office or Remote
St. Louis, MO
111K-157K Annually
Senior level
111K-157K Annually
Senior level
eCommerce • Fintech • Information Technology • Payments • Financial Services
Lead end-to-end delivery of technology implementations and solution rollouts, managing scope, schedules, budgets, risks, issues, vendors, internal teams, and executive stakeholders. Create project plans and status reports, facilitate meetings, track milestones, and ensure deliverables align with business objectives. The role requires banking industry knowledge and a general understanding of technology ecosystems used by financial institutions.
5 Days AgoSaved
Remote
St. Louis, MO
130K-140K Annually
Senior level
130K-140K Annually
Senior level
Edtech • Software
Leads complex, cross-functional initiatives spanning software, digital content, service design, and physical materials. Owns critical paths, launch readiness, risk mitigation, resource planning, project rituals, vendor performance, and stakeholder communication. Uses Agile/Scrum and Waterfall/Stage-Gate methods, project dashboards, metrics, and process improvements to coordinate teams and deliver high-quality products on schedule.
Top Skills: AgileAirtableJIRAMonday.ComScrumSmartsheetStage-GateWaterfall
Reposted 5 Days AgoSaved
Remote
St. Louis, MO
100K-120K Annually
Senior level
100K-120K Annually
Senior level
Healthtech
Lead end-to-end, multi-state enterprise implementations across 10 workstreams, coordinating cross-functional teams, timelines, and escalations. Post-launch, act as primary partner relationship owner to monitor KPIs, run quarterly business reviews, identify expansion opportunities, and develop scalable implementation playbooks.
Top Skills: Crm SystemsEhr SystemsHubspotProject Management Tools
Senior level
Edtech
Lead technical project delivery and roadmap evolution for content authoring platforms. Translate business goals into technical requirements, guide design discussions, manage integrations and data interoperability, and coordinate with vendors and education agencies. Investigate production issues using SQL Server and log analysis, oversee deployments with DevOps and SRE teams, support QA, mitigate technical risks, and maintain technical documentation.
Top Skills: ClaudeConfluenceDevOpsGithub CopilotLarge Language ModelsQtiRestful ApisSQL ServerSreVector SearchWebhooks
5 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
AdTech
Leads strategic and operational initiatives for Internal Products within the Engineering PMO. Responsibilities include project planning, scope and risk management, agile delivery practices, backlog and intake management, capacity forecasting, cross-functional stakeholder coordination, Jira Service Management workflows, delivery metrics, process documentation, and release communications. The role supports internal platforms, including Salesforce and other revenue technology systems, while improving delivery predictability and operational efficiency.
Top Skills: APIsETLGongHubspotJira Service ManagementJira SoftwareKanbanLeandataMarketoOutreachSalesforceScrumSQLZendesk
Reposted 5 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Consulting • Design • Web3
Lead and coordinate client-facing technical implementations for web, webapp, and mobile projects. Manage cross-functional teams, schedules, finances, documentation, QA/UAT, and project management tools to ensure scope, sprints, and deployments stay on track while keeping clients informed.
Top Skills: JIRA
Reposted 5 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Information Technology • Consulting
Lead Oracle Cloud EPM implementation projects from initiation to closure, manage scope, schedule, budget, risks, and quality. Coordinate stakeholders, assemble and direct cross-functional teams, ensure deliverables meet client expectations, and apply Agile/Scrum practices and change management to drive successful project outcomes.
Top Skills: AgileJIRAMicrosoft ProjectOracle CloudOracle Cloud EpmScrumSmartsheetTrello
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