Top Senior Software Engineer Jobs in St. Louis, MO

Reposted 6 Days AgoSaved
Remote
St. Louis, MO
136K-166K Annually
Senior level
136K-166K Annually
Senior level
Big Data • eCommerce • Fintech • Analytics • Agriculture
Design and maintain high-quality software solutions for an eCommerce platform, focusing on back-end systems and collaborating with various teams.
Top Skills: AWSC++GoJavaMySQLPostgresPython
Reposted 6 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Information Technology • Consulting
Design and build applications using Python, manage component design, optimize performance, and collaborate with clients on innovative products.
Top Skills: Ai ToolsCi/CdGitGoKubernetesPythonReact
Reposted 6 Days AgoSaved
Remote or Hybrid
St. Louis, MO
125K-135K Annually
Senior level
125K-135K Annually
Senior level
Healthtech
As a Software Engineer II, you will design, build, and maintain applications for a healthcare quality data platform, collaborating with teams to develop features and ensure high standards of performance and security.
Top Skills: AIGraphQLPostgresReactRubyRuby On Rails
Reposted 6 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Payments • Sales • Software • Financial Services
Design, build, and operate reliable and scalable systems to support Anrok's product, focusing on technical debt, security, and performance optimization.
Top Skills: GCPPostgresPulumiTypescript
Reposted 6 Days AgoSaved
Remote
St. Louis, MO
141K-208K Annually
Senior level
141K-208K Annually
Senior level
Database • Analytics
The Cloud Software Engineer will design and operate distributed systems for ClickHouse's Observability platform, ensuring reliability and efficiency while working with various engineering and infrastructure teams.
Top Skills: ArgocdAWSAzureGCPGoGrafanaHelmKubernetesOpentelemetryPrometheusTerraform
Reposted 6 Days AgoSaved
Remote
St. Louis, MO
141K-208K Annually
Senior level
141K-208K Annually
Senior level
Database • Analytics
Develop and maintain ClickHouse Cloud interfaces and dashboards, collaborating with multi-disciplinary teams to enhance user experience and system reliability.
Top Skills: AWSAzureGCPJavaScriptNode.jsReactServerlessTypescript
Reposted 6 Days AgoSaved
Remote
St. Louis, MO
150K-170K Annually
Senior level
150K-170K Annually
Senior level
Healthtech
Design, develop, and maintain scalable software solutions, collaborating with cross-functional teams and mentoring junior developers to enhance Arine's web applications and APIs.
Top Skills: AWSGitPythonRestful ApisTypescript
7 Days AgoSaved
Remote
St. Louis, MO
140K-190K Annually
Senior level
140K-190K Annually
Senior level
Artificial Intelligence • Legal Tech • Natural Language Processing • Generative AI
Senior backend engineer responsible for designing and implementing new features, scaling and optimizing the platform, improving Postgres and Elasticsearch performance, fine-tuning LLMs, and making architectural decisions. Collaborate with engineering team, take ownership of features, write performant, maintainable code, and help shape product and infrastructure for data-intensive applications (NLP, search, indexing).
Top Skills: AWSDaggerDockerDropwizardElasticsearchIndexingJavaJava 21JooqKerasLlmsNlpPostgresSearchTensorFlow
7 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Artificial Intelligence • Legal Tech • Natural Language Processing • Generative AI
Design and implement front-end features, build high-quality user interfaces, take ownership of product and architecture decisions, collaborate with engineering team, and deliver performant, user-focused solutions.
Top Skills: AWSDockerElasticsearchJavaNextjsPostgresReactReduxTypescript
Reposted 12 Days AgoSaved
Remote
St. Louis, MO
170K-240K Annually
Senior level
170K-240K Annually
Senior level
Fintech • Information Technology • Software
As a Senior Software Engineer on the Data Platform team, you'll enhance the data infrastructure, develop ETL pipelines, maintain data quality, collaborate across teams, and mentor junior engineers.
Top Skills: AWSDockerEmrGoLambdaOpensearchPostgresPythonRedshiftSpark
Reposted 12 Days AgoSaved
Remote
St. Louis, MO
193K-309K Annually
Senior level
193K-309K Annually
Senior level
Cloud • Fintech • Food • Information Technology • Software • Hospitality
The Staff Software Engineer will architect and code backend services and ML models, integrate systems, ensure quality, and mentor engineers in the AI & Strategy Engineering team.
Top Skills: AWSGoJavaLambdaLangchainLlmsMlPythonRag ArchitecturesSagemakerSalesforceSqs
7 Days AgoSaved
Remote
St. Louis, MO
104K-162K Annually
Senior level
104K-162K Annually
Senior level
HR Tech • Consulting
Design, build, test, and deploy production software for an agentic chatbot platform across intake, orchestration, retrieval, answer generation, caching, and integrations. Deliver clean code, participate in sprint work, review merge requests, collaborate with product and architecture, mentor junior engineers, and contribute to design and delivery decisions to solve conversational AI problems within a benefits ecosystem.
Top Skills: APIsBackend Service DevelopmentCSSFastapiHTMLJavaJavaScriptJqueryOpenai (Llm Apis)Prompt DesignPythonSQLXML
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Reposted 7 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Mobile • Software
The Senior Software Engineer will enhance efficiency in procurement for the Department of War by developing web applications, managing technical delivery, and mentoring team members.
Top Skills: AngularAWSDockerJavaJavaScriptMongoDBNode.jsPostgresSpringTypescript
Reposted 7 Days AgoSaved
Remote
St. Louis, MO
93K-147K Annually
Senior level
93K-147K Annually
Senior level
Software • Financial Services
As a Java Software Engineer III, you will design, develop, and maintain scalable Java-based backend services, mentor other engineers, and influence architectural decisions in an agile environment.
Top Skills: AzureAzure DevopsDockerGitJavaJavaScriptJenkinsKubernetesPythonRestSoapSpring BootSpring JpaSpring SecuritySQLTerraform
8 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Real Estate
Lead development of a new iOS mobile product: implement LiDAR/AR scanning, floor-plan rendering, offline-first sync with FastAPI backend, prototype visualizations, integrate backend/ML work, and own subsystems end-to-end on a small, fast-moving team using AI coding agents.
Top Skills: @MainactorActorsAi Coding AgentsArArkitCiClaude CodeCodableCore DataFastapiLidarMetalPythonRoomplanScenekitSendableSimdSwiftSwift 6Swift ConcurrencySwiftdataSwiftuiUrlsessionXcodebuild
8 Days AgoSaved
In-Office or Remote
St. Louis, MO
130K-180K Annually
Senior level
130K-180K Annually
Senior level
Artificial Intelligence • HR Tech • Conversational AI • Automation
Join as an early founding full-stack engineer to architect, build, and deploy a scalable platform serving AI-driven voice applications. You will own frontend and backend development, design infrastructure with the CTO, and deliver reliable production systems for enterprise customers.
Top Skills: FastapiNextjsPythonReactTailwindcss
Reposted 13 Days AgoSaved
Easy Apply
Remote or Hybrid
St. Louis, MO
Easy Apply
200K-250K Annually
Senior level
200K-250K Annually
Senior level
Artificial Intelligence • Machine Learning
Develop and manage high-performance back-end systems, design secure APIs, optimize performance in cloud environments, conduct testing, and manage ML model lifecycles.
Top Skills: SparkAWSAzureDockerGCPGoJavaKubeflowKubernetesMlflowPythonScala
Reposted 13 Days AgoSaved
Easy Apply
Remote
St. Louis, MO
Easy Apply
167K-231K Annually
Senior level
167K-231K Annually
Senior level
Artificial Intelligence • Fintech • Machine Learning • Social Impact • Software
Lead technical direction for software architecture and cross-team initiatives focusing on scaling consumer-facing systems and maximizing loan originations while maintaining compliance and system integrity.
Top Skills: AWSCi/CdDockerGithub ActionsInfrastructure As CodeReactRuby On Rails
Reposted 13 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Artificial Intelligence • Machine Learning • Software • Defense
Design and build agent-powered mission consoles, collaborate with stakeholders to improve user workflows, and maintain agentic workflows for mission outcomes.
Top Skills: AWSNode.jsPostgresPythonReactTailwindTypescript
Reposted 13 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Artificial Intelligence • Machine Learning • Software • Defense
As a Senior Software Engineer, you will design and build a cutting-edge identity search platform and implement AI systems for defense applications, working closely with cross-functional teams to enhance user workflows and support national security.
Top Skills: AWSElasticsearchNode.jsOpensearchPostgresReactTailwindTypescript
Reposted 13 Days AgoSaved
Easy Apply
Remote or Hybrid
St. Louis, MO
Easy Apply
162K-390K Annually
Senior level
162K-390K Annually
Senior level
Artificial Intelligence • Cloud • Computer Vision • Hardware • Internet of Things • Software
The Senior Staff Software Engineer will lead major projects, drive architectural innovation, interface with customers for solutions, and mentor engineers. Experience in software engineering and a strong grasp of AI, cloud scale, and evolving technologies is essential.
Top Skills: AIAWSAzureCloud ServicesSoftware Engineering
14 Days AgoSaved
Easy Apply
Remote
St. Louis, MO
Easy Apply
167K-231K Annually
Senior level
167K-231K Annually
Senior level
Artificial Intelligence • Fintech • Machine Learning • Social Impact • Software
As a Senior Software Engineer, you'll design and develop scalable services for real-time pricing, collaborate with cross-functional teams, and ensure system reliability through testing and monitoring.
Top Skills: AWSGCPJavaKotlinPython
14 Days AgoSaved
Remote or Hybrid
St. Louis, MO
75K-257K Annually
Senior level
75K-257K Annually
Senior level
Consumer Web • Coupons • Healthtech • Social Impact • Pharmaceutical
As a Senior Software Engineer, you will design frontend architectures, collaborate with backend engineers, mentor others, and utilize AI tools for efficient development.
Top Skills: Ci/CdContextGraphQLNext.JsReactReduxRest ApisTypescript
Reposted 8 Days AgoSaved
In-Office or Remote
St. Louis, MO
135K-225K Annually
Senior level
135K-225K Annually
Senior level
Aerospace • Defense • Manufacturing
The AI Assisted Software Engineer will design and develop enterprise software solutions, utilizing AI-assisted tools, and architect scalable systems while collaborating across teams to improve business operations.
Top Skills: Cloud PlatformsDockerJavaScriptNext.JsNode.jsPostgresPythonReactTypescript
Reposted 8 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Cloud
Design and implement cloud solutions for clients, leading teams, solving technical challenges, and utilizing modern technologies like Kubernetes and AI.
Top Skills: AICi/CdGithub ActionsGitlabGoGCPKubernetesLangchainLlmsPythonStreamlit
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