Top Senior Software Engineer Jobs in St. Louis, MO

Lead a development team while remaining hands-on in full-stack engineering. Design, build, test, deploy, and support secure web applications using C#/.NET, Angular, databases, and AWS. Drive cloud migrations, architecture, CI/CD automation, application security, troubleshooting, performance and cost optimization. Mentor developers, establish engineering standards, lead technical delivery, and collaborate with product, data, DevOps, and architecture teams.

Own commercial navigation features end to end across mobile, backend, and web surfaces. Build reliable, customer-facing navigation experiences for commercial fleets despite poor connectivity, dynamic schedules, and changing routes. Define product priorities and success metrics, ship maintainable and tested code, improve observability, and collaborate with product, design, Maps, Telematics, and adjacent engineering teams. The role requires strong customer focus, technical depth, and the ability to make practical tradeoffs in ambiguous problem spaces.

Drive projects that improve AI agent effectiveness across software development workflows. Build and maintain reliable developer tooling, iOS frameworks, libraries, build systems, and testing infrastructure. Collaborate with cross-functional partners to improve developer productivity, increase AI agent efficiency and reliability, and deliver roadmap initiatives across large-scale codebases.

Design, build, and operate scalable distributed systems for real-time restaurant payment and financial workflows. Responsibilities include architecting reliable services, protecting sensitive financial data, improving observability and production performance, debugging distributed systems, participating in on-call rotations, applying AI-assisted engineering tools, collaborating cross-functionally, and mentoring engineers.

Design and implement experiments deep within browser engine subsystems, including DOM, layout, rendering, accessibility, JavaScript runtimes, and networking. Investigate browser behavior, prototype capabilities for programmatic web interaction, measure performance and correctness, profile overhead, and document results. The role requires hands-on systems engineering, browser platform expertise, large-codebase development, and collaboration on AI-agent tooling.

Build and operate foundational developer infrastructure across CI, build systems, deployment orchestration, and test platforms. Improve build speed, deployment safety, test reliability, observability, and engineering productivity at scale. Own services from architecture through production, including SLOs and on-call operations. Lead cross-functional technical projects, partner with engineering teams, mentor engineers, and shape platform strategy.

Build and ship customer-facing transaction features end to end, including APIs, data models, pipelines, integrations, and user interfaces. Collaborate with product and design teams, contribute high-quality code, drive technical discussions, identify risks, and deliver production systems using a modern Python stack.

Develop and maintain full-stack TypeScript applications using React, Node.js, and PostgreSQL. Build intuitive user interfaces, scalable APIs, and secure systems; collaborate on architecture, code reviews, testing, deployments, incident response, and infrastructure improvements. Mentor engineers, reduce technical debt, participate in Agile ceremonies, and support production systems in a remote-first environment.

Build and maintain full-stack software supporting patient-centered healthcare products. Contribute to architecture, technical standards, code reviews, design discussions, and reliable implementation. Collaborate with product managers, designers, and stakeholders, while advocating for privacy, security, and access to care. Mentor engineers, document knowledge, identify technical improvements, and help shape project direction. The role requires backend, database, cloud, and AI development-tool experience in a fully remote environment.

Build full-stack software, backend services, APIs, frontend experiences, and shared integration capabilities supporting AI initiatives across Keeper’s products. Integrate LLMs, agents, and tool-calling workflows into secure production environments while maintaining zero-knowledge principles. Troubleshoot cross-product systems, improve reliability and observability, contribute to architecture and code reviews, automate testing and CI/CD, and collaborate with AI, product, and engineering teams.

Lead development of a massively distributed edge compute platform. Design fault-tolerant systems, external APIs, high-throughput traffic routing, and Kubernetes-based resource management. Establish architecture standards, reliability metrics, security practices, and technical governance. Collaborate with AI/ML, hardware, networking, and security teams; communicate risks to executives; manage customer requirements; review code; and mentor engineers on distributed systems best practices.

Build and scale backend systems for a high-traffic donor CRM and payments platform. Own performant SQL and realtime querying, optimize payment flows, implement AI agents, and collaborate across product and design to ship resilient, production-grade features at scale.

Build and operate Conduit’s control plane services for provisioning, updating, repairing, and retiring customer infrastructure. Design reconciliation-based lifecycle systems, schema-driven APIs, usage metering, internal tooling, and integrations with billing and partner systems. Own contracts, versioning, reliability, asynchronous workflows, and cross-functional coordination. Participate in on-call support while improving platform maintainability and automation.

Build and operate Conduit's control plane services for provisioning, updating, repairing, and retiring customer infrastructure. Design schema-driven lifecycle systems, usage metering, APIs, contracts, internal tooling, and integrations with billing and partner systems. Ensure reliability through reconciliation, event-driven workflows, idempotency, retries, and eventual consistency. Own cross-team interfaces, improve maintainability, participate in on-call, and debug complex production issues across networking, performance, data integrity, and security boundaries.

Designs and maintains automated testing frameworks for AI-powered applications, APIs, backend services, and distributed systems. Defines test strategies, acceptance criteria, evaluation metrics, tolerances, and quality gates for deterministic and non-deterministic software. Builds regression, integration, API, and end-to-end coverage; evaluates LLMs, agents, prompts, and tool-calling workflows; integrates testing into CI/CD; analyzes failures, telemetry, and logs; reduces flaky tests; and partners with AI, engineering, and product teams on continuous quality practices.

Lead the technical vision for test automation and quality architecture across cloud, web, and mobile systems. Design scalable testing frameworks, integrate automation into CI/CD pipelines, analyze quality metrics, mentor engineers, guide technical decisions, and communicate outcomes to engineering leadership. The role emphasizes Playwright with TypeScript, Maestro with YAML, API and integration testing, system validation, and AI-first automation practices.

Build and operate secure, scalable multi-cloud infrastructure across AWS, GCP, and networking platforms. Develop self-service tooling, infrastructure-as-code defaults, cloud guardrails, and standardized platform patterns. Lead cross-team infrastructure initiatives, technical investigations, and operational improvements while partnering with security, compute, routing, and other infrastructure teams.

Build and operate blockchain network infrastructure integrating protocols such as Bitcoin and Ethereum with internal services. Design reliable APIs, SDKs, data contracts, observability, and SLOs; lead multi-quarter chain integrations, architecture modernization, and migrations. Improve latency, reliability, and cost for high-throughput distributed systems while owning production services and on-call responsibilities.

Design, build, and maintain scalable cloud infrastructure using AWS, GCP, or Azure. Implement SRE practices, monitoring, observability, capacity planning, Kubernetes and Helm deployments, CI/CD pipelines, automation, and cloud security controls. Collaborate with cross-functional teams, ensure compliance, and mentor engineers while improving reliability, availability, scalability, and performance.

Develop and architect scalable Java software for NinjaOne’s endpoint management platform. The role involves building high-availability services, leading technical initiatives, making architectural decisions, improving quality practices, collaborating cross-functionally, mentoring engineers, and addressing scalability, performance, and technical debt challenges.

Develop and scale backend patch-management software using Java and Kotlin for millions of endpoints. Implement enterprise software, design scalable systems, build REST services, work with relational databases and caching systems, and uphold rigorous testing and quality standards. Collaborate with AI workflow, server, platform, design, and product teams. React or Angular experience may support occasional frontend work.

Build and maintain scalable AWS infrastructure using Terraform and AWS CDK. Design highly available cloud environments, automate operational workflows with TypeScript, implement policy-as-code guardrails, optimize cloud costs, and lead disaster recovery planning and testing. The role also involves CI/CD, Kubernetes, networking, identity platforms, cross-team consensus building, project ownership, communication, and mentoring junior engineers.

Design, develop, secure, and maintain mission-critical Microsoft-platform software for DoD programs. Build C# and .NET applications, responsive JavaScript and EXT JS interfaces, REST APIs, and optimized SQL Server databases. Apply secure coding, STIG, RMF, threat modeling, vulnerability remediation, documentation, and compliance practices. Integrate Kiro AI capabilities, collaborate with cybersecurity and engineering teams, and support deployment and sustainment in classified or controlled environments.

Build Exoware’s production infrastructure from the ground up, including deployment, scaling, upgrades, recovery, CI/CD, monitoring, telemetry, security, and operational tooling. Design reliable systems across Kubernetes, ECS, cloud services, networking, and storage while writing software to automate operations. The role requires architectural ownership, production infrastructure experience, and the ability to improve the underlying distributed systems through production insights.

Lead front-end architecture and cross-team technical initiatives for the NodeZero platform. Build scalable React and TypeScript systems, reusable components, developer tooling, and shared frameworks while improving performance, reliability, accessibility, observability, and CI/CD workflows. Mentor engineers, establish engineering standards, guide technical strategy, reduce technical debt, and collaborate with Product, Design, Platform, Security, and engineering teams.