Top Senior Software Engineer Jobs in St. Louis, MO

17 Days AgoSaved
Remote
St. Louis, MO
139K-204K Annually
Senior level
139K-204K Annually
Senior level
Productivity • Software • Conversational AI
The role involves designing, building, and optimizing a data platform, collaborating with cross-functional teams, and ensuring data quality and security.
Top Skills: AirflowAthenaAws LakeformationGlueHiveHudiJavaKafkaPrestoPythonScalaSpark
22 Days AgoSaved
Remote
St. Louis, MO
173K-203K Annually
Senior level
173K-203K Annually
Senior level
Healthtech • Other • Social Impact • Software • Telehealth
The Senior Software Engineer will develop scalable web applications, lead technical projects, design complex systems, and enhance engineering culture through mentoring and collaboration.
Top Skills: Ai-Assisted Development ToolsNode.jsPostgresReactTypescript
22 Days AgoSaved
Remote
St. Louis, MO
173K-203K Annually
Senior level
173K-203K Annually
Senior level
Healthtech • Social Impact • Software • Telehealth
As a Fullstack Senior Software Engineer, you'll design and scale systems, lead technical projects, and enhance mental health care access through software at Rula.
Top Skills: AWSDockerGCPKubernetesNode.jsPostgresReactTypescript
Reposted 22 Days AgoSaved
Remote
St. Louis, MO
155K-170K Annually
Senior level
155K-170K Annually
Senior level
Software
As a Senior Software Engineer at Desmos, you'll develop innovative math tools, lead projects, and collaborate across teams to enhance user experiences.
Top Skills: CSSHTMLPostgresTypescript
Reposted 22 Days AgoSaved
Easy Apply
In-Office or Remote
St. Louis, MO
Easy Apply
119K-160K Annually
Senior level
119K-160K Annually
Senior level
AdTech • Digital Media • Marketing Tech • Software • Automation
The Sr Software Engineer will enhance platform performance, develop cloud-native systems, improve CI/CD processes, and oversee deliverables while collaborating with feature teams.
Top Skills: AirbrakeAWSDatadogDockerEc2JavaJavaScriptKafkaKubernetesPostgresPythonRabbitMQRuby on RailsRdsReactRedisRubySidekiqTerraform
Reposted 22 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Artificial Intelligence • Machine Learning • Software • Defense
As a Senior Software Engineer, you will design best practices for AI Agents, develop standards, collaborate on product opportunities, and stay updated on emerging Agent techniques.
Top Skills: Agent FrameworksAPIsClaude SdkCloud InfrastructureDistributed SystemsGoogle AdkLanggraph
23 Days AgoSaved
Easy Apply
Remote
St. Louis, MO
Easy Apply
167K-231K Annually
Senior level
167K-231K Annually
Senior level
Artificial Intelligence • Fintech • Machine Learning • Social Impact • Software
The Senior Software Engineer will design and build scalable backend services for loan origination, improving reliability and operational efficiency. Responsibilities include modernizing infrastructure, supporting partner onboarding, and collaborating across teams to enhance lending processes.
Top Skills: Ruby On Rails
Reposted 17 Days AgoSaved
Remote
St. Louis, MO
160K-200K Annually
Senior level
160K-200K Annually
Senior level
Healthtech • Information Technology • Kids + Family • Software
Develop full-stack features for both parent-facing and physician platforms using Django and Hotwire. Collaborate with product managers and improve health outcomes for children. Take ownership of projects and implement high-quality software.
Top Skills: DjangoHotwireReact NativeSQLWebrtc
Reposted 17 Days AgoSaved
Remote
St. Louis, MO
119K-206K Annually
Senior level
119K-206K Annually
Senior level
eCommerce • Retail
The MTS 1, Software Engineer at eBay will design and develop scalable applications, APIs, and server-side processing while collaborating with product teams and mentoring developers.
Top Skills: ApacheCSSGitHTMLJavaScriptJqueryMssqlMySQLPHPPhp Mvc FrameworksReactVue
23 Days AgoSaved
Remote
St. Louis, MO
207K-243K Annually
Senior level
207K-243K Annually
Senior level
Healthtech • Other • Social Impact • Software • Telehealth
The Staff Software Engineer will lead technical projects for the Patient Matching team, focusing on scalable systems and API design. Responsibilities include system architecture, mentoring engineers, and collaborating with various stakeholders to enhance patient experiences in mental healthcare.
Top Skills: Ai-Assisted Development ToolsApi DesignData Modeling
Reposted 23 Days AgoSaved
Easy Apply
Remote
St. Louis, MO
Easy Apply
196K-247K Annually
Senior level
196K-247K Annually
Senior level
Artificial Intelligence • Fintech • Healthtech • Software
Lead design and evolution of data interfaces, mentor team, support integrations for live clients, and enhance data tools for scalability and efficiency.
Top Skills: Apache AirflowDagsterDbtDjangoFhirFivetranGoHl7KafkaKotlinPythonSnowflakeSql AlchemyX12
Reposted 23 Days AgoSaved
Easy Apply
Remote
St. Louis, MO
Easy Apply
167K-231K Annually
Senior level
167K-231K Annually
Senior level
Artificial Intelligence • Fintech • Machine Learning • Social Impact • Software
Design and build scalable systems for Upstart Bank, translating regulatory requirements into software, improving reliability, and ensuring audit-readiness while collaborating with multiple teams.
Top Skills: GrpcJavaKafkaKotlinPython
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Reposted 18 Days AgoSaved
Remote
St. Louis, MO
125K-156K Annually
Senior level
125K-156K Annually
Senior level
Healthtech • Software
The Full Stack Software Engineer will design, maintain scalable solutions, and collaborate with teams to enhance software quality, focusing on Ruby on Rails and AI integration.
Top Skills: AWSAzureCSSGCPHTMLJavaScriptNoSQLRuby On RailsSQL
Reposted 18 Days AgoSaved
Remote
St. Louis, MO
125K-156K Annually
Senior level
125K-156K Annually
Senior level
Healthtech • Software
The Full Stack Software Engineer will design and maintain scalable applications, focusing on Ruby on Rails, and collaborate with teams to enhance software quality and performance. Key responsibilities include troubleshooting, optimizing systems, and integrating AI solutions.
Top Skills: AWSAzureCi/CdCSSGCPHTMLJavaScriptNoSQLRuby On RailsSQL
Reposted 18 Days AgoSaved
Remote
St. Louis, MO
150K-250K Annually
Senior level
150K-250K Annually
Senior level
Hardware • Information Technology • Software
The Senior Software Engineer will develop high-performance software for executing open-source LLMs on custom hardware, focusing on optimizations and efficient libraries primarily in C++.
Top Skills: Avx-512C++ClangFpgaGccHpcLlvmMlSimdSse
Reposted 18 Days AgoSaved
Remote
St. Louis, MO
200K-255K Annually
Senior level
200K-255K Annually
Senior level
Hardware • Healthtech • Retail
As a Senior RPA Integration Engineer, you will design and implement RPA solutions for healthcare imaging systems, focusing on enhancing scheduling workflows and operational efficiency.
Top Skills: Automation AnywhereFhirHl7Power AutomatePythonRestful ApisRpaUipath
Reposted 18 Days AgoSaved
Remote
St. Louis, MO
128K-267K Annually
Senior level
128K-267K Annually
Senior level
AdTech • Digital Media • Information Technology • Other
The Senior Full Stack Engineer will design and operate identity systems, implement AI-driven efficiencies, mentor engineers, and ensure high-quality code in an AI-first environment.
Top Skills: AIAWSAzure)Ci/CdCloud (GcpGrafana)JavaNode.jsObservability (SplunkReactSpec-Driven DevelopmentTypescript
Reposted 24 Days AgoSaved
Easy Apply
Remote
St. Louis, MO
Easy Apply
124K-155K Annually
Senior level
124K-155K Annually
Senior level
Digital Media • eCommerce • Information Technology • Marketing Tech • Pet • Retail • Social Media
The Lead Software Engineer in Test will own test automation strategy, design automation frameworks, integrate testing into CI/CD, and mentor QA engineers to enhance quality across engineering processes.
Top Skills: AppiumC#CypressGithub ActionsGitlab CiJavaJenkinsJestPlaywrightPythonRestassuredSeleniumTypescript
Reposted 19 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Fintech
As a Software Engineer, you'll design and develop microservices using a cloud-native tech stack, with a focus on financial services and secure systems.
Top Skills: Aws KinesisGoGrpcIstioJaegerKubernetesPostgresPythonTemporalTypescript
Reposted 19 Days AgoSaved
Remote
St. Louis, MO
100K-130K Annually
Senior level
100K-130K Annually
Senior level
Cloud • Software • Database
Develop and maintain scalable, fault-tolerant components for YB Anywhere to automate deployment and management of YugabyteDB across cloud and on-prem environments. Collaborate with product, frontend, QA, and DevOps teams, perform code reviews, mentor engineers, and improve operational workflows and performance.
Top Skills: DockerGoJavaKubernetesPostgresYugabytedb
Reposted 19 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Healthtech • Information Technology • Software
The Software Engineer IV will develop and maintain payer customer implementations, primarily focusing on back-end development, and mentor junior team members.
Top Skills: AWSJavaJavaScriptReactRestful ApisSql DatabasesVueWeb Services
Reposted 19 Days AgoSaved
Remote
St. Louis, MO
5-5 Annually
Senior level
5-5 Annually
Senior level
Mobile • Software
The Software Engineer will develop full-stack features using Java and Angular, build microservices, integrate APIs, and optimize system performance for the Air Force aircraft maintenance platform.
Top Skills: AngularApigeeDockerGCPGradleJavaKafkaKubernetesMavenMySQLPostgresSpring Boot
Reposted 6 Days AgoSaved
In-Office
St. Louis, MO
105K-204K Annually
Senior level
105K-204K Annually
Senior level
Greentech • Hardware • Energy
The Senior Software Engineer analyzes, designs, and implements software projects, focusing on Oracle EPM solutions and cloud configurations, and mentors less experienced developers.
Top Skills: EssbaseFdmeeFinancial Reporting StudioMulesoftOdiOracle Cloud EpmOracle EpmSmartview
Reposted 20 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Database
Responsible for designing and implementing authentication features in Go and TypeScript, enhancing Auth architecture, and collaborating with teams to improve user experience.
Top Skills: DjangoGoJwtLaravelNext.JsOauthOidcPostgresRuby On RailsSAMLTypescript
Reposted 20 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Fintech • Financial Services
Lead and execute Growth engineering work to drive acquisition, activation, and retention. Build experimentation systems, collaborate cross-functionally, analyze user data to inform product decisions, mentor engineers, balance technical debt and feature development, and foster a culture of ownership and continuous improvement.
Top Skills: A/B Testing FrameworksAmplitudeBilling SystemsExperimentation InfrastructureInternal AnalyticsPythonReactSegmentTypescript
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