Top Machine Learning Jobs in St. Louis, MO

Lead the design, development, deployment, and operation of production AI and ML systems. Build high-throughput Python services and Databricks pipelines, support traditional ML and LLM applications, establish testing and deployment standards, and develop monitoring for quality, reliability, latency, throughput, and cost. Partner with product, research, and responsible AI teams on governance and release criteria. Provide architectural leadership, conduct code reviews, mentor engineers, and resolve complex technical dependencies.

Develop AI and machine learning solutions for fraud, anomaly detection, semantic search, entity resolution, and investigative analytics. Build and operationalize models across structured and unstructured data using AWS data lakehouse services, generative AI, NLP, graph analytics, and document intelligence. Evaluate model performance, explainability, monitoring, and risk scoring while supporting production integration, dashboards, and investigative workflows. Collaborate with technical teams, investigators, stakeholders, and federal clients in an Agile environment.

Leads client-facing data science and analytics initiatives, translating complex marketing and media data into actionable business narratives. Develops measurement strategies, including test/holdout incrementality, informs acquisition and retention decisions, scales analytics best practices, and manages analyst teams. Partners with Sales, Client Services, Operations, and other stakeholders while supporting predictive and adaptive AI/ML solutions. The role requires strong client communication, strategic leadership, analytics expertise, and proficiency with Python, SQL, Tableau, and related tools.

Build and ship production AI systems for enterprise portfolio and planning workflows. Develop anomaly and signal detection, LLM-powered insight synthesis, natural-language planning rule translation, evaluation frameworks, and MCP tools. Partner with external AI providers initially, then establish internal standards for prompt design, model selection, agent architecture, reliability, and evaluation. Collaborate closely with product, design, and domain engineering teams.

Leads data engineering, Palantir Skywise architecture, and AI solution development for Airbus manufacturing and operational environments. Builds scalable pipelines, analytical workflows, machine learning and generative AI applications, and enterprise data foundations. Oversees Alteryx and Tableau platforms, establishes governance, mentors technical teams, translates business challenges into data products, and supports AI Center of Excellence initiatives. The role is onsite 60% across several U.S. locations and requires approximately 10% travel.

Leads the bankruptcy risk solutions product portfolio across the Americas, owning product vision, strategy, roadmap, execution, customer discovery, and commercialization. Partners with Engineering, Data Science, Sales, Marketing, Client Success, and enterprise customers to develop data-driven products, manage backlogs in Jira, support migrations, monitor KPIs, and drive adoption, growth, and product-market fit.

Develop, implement, and deploy scalable machine learning models for healthcare solutions. Collaborate cross-functionally to integrate models, analyze data to improve performance, ensure data quality, and stay current with ML advancements to support patient care and operational efficiency.

Leads and builds the mid-market business development function, owning territory strategy and the full sales cycle for pharma and biotech accounts. Develops and coaches a high-performing BD team, drives pipeline and new-logo acquisition, closes multi-year SaaS deals, and partners with marketing, strategy, product, and commercial operations. Represents the company at industry events and contributes to commercial frameworks, forecasting, segmentation, and coverage models.

Lead technical product strategy and execution for AI-powered learning intelligence infrastructure. Own roadmaps for AI curation, data ingestion, recommendation algorithms, learner profiles, analytics, and platform interoperability. Translate architecture, research, data, and business requirements into technical specifications, backlogs, success criteria, and implementation plans. Coordinate cross-functional stakeholders, manage delivery risks, and ensure systems are explainable, privacy-aware, validated, and aligned with educator and learner needs.

Manage a portfolio of B2B SaaS customers in the HR technology space, driving renewals, expansions, and revenue growth. Build strategic client relationships, conduct business reviews, monitor customer health, manage renewal and sales cycles, introduce products, and advocate for customers internally. The role requires strong sales acumen, analytical abilities, HR technology expertise, and experience influencing HR and L&D decision-makers. It also includes identifying adoption barriers, creating customer feedback loops, and mentoring others.

Design, develop, optimize, and deploy scalable computer vision and vision-language systems using classical computer vision and deep learning. Build evaluation frameworks, monitor production models, debug issues, and improve architectures with new data. Collaborate with product managers and cross-functional teams to deliver practical AI solutions across cloud and edge environments.

Leads an enterprise Account Executive team across a U.S. region, owning pipeline, revenue, forecasting, account planning, sales processes, onboarding, coaching, and growth targets. Supports strategic customer deals, partners with marketing on account-based campaigns, builds utility-industry relationships, and represents Neara at customer sites and industry events. The role also develops user groups and customer feedback loops to inform product direction.

Design and productionize ML models and agentic systems for intraday financial alpha generation. Build data pipelines, experiment frameworks, and portfolio optimization methods. Collaborate with quants and engineers to move models from research to live trading environments.

Leads enterprise AI and intelligent automation strategy, including Generative AI, machine learning, and RPA initiatives. Manages a multidisciplinary IT team, budgets, vendors, governance, project portfolios, and end-to-end solution delivery. Partners with business and technology leaders to identify automation opportunities, develop business cases, ensure compliance and security, and deliver scalable solutions with measurable business value. The role is hybrid in Camden, New Jersey, with 15% domestic and international travel.

Leads the end-to-end design, deployment, and performance of real-time ML prediction and bid-optimization systems for programmatic advertising. Provides hands-on technical leadership to applied scientists and ML engineers, formulates optimization problems, manages production ML challenges such as latency, delayed feedback, drift, and retraining, and aligns technical roadmaps with business priorities.

Develop statistical and machine learning models using soccer tracking and event data to support player recruitment decisions. Build spatio-temporal models, metrics, analyses, and interpretation tools; validate models; communicate findings to professional club clients; and partner with engineering on cloud deployment and production reliability. The role also includes code review, model maintenance, and advancing analytical methods.

Design, build, evaluate, and deploy LLM-powered agents and machine learning systems that improve Quora content quality and safety. The role involves developing agentic workflows, conducting offline and online evaluations, monitoring production performance, investigating failures, and improving accuracy, reliability, latency, and cost. New graduates will collaborate with experienced engineers and own projects from development through production.

Leads enterprise product evaluations, implementations, integrations, and adoption initiatives. Manages cross-functional projects involving AI, automation, system modernization, and third-party platforms. Translates business requirements into implementation plans, develops business cases and ROI analyses, coordinates vendors and stakeholders, prepares executive communications, assesses risks, and supports organizational change and user adoption.

Owns the intelligence platform roadmap for enterprise healthcare engagement, including decisioning, orchestration, integrations, interoperability, identity and consent management, and scalable deployment. The role defines strategy and requirements, prioritizes platform investments, leads partner integrations, establishes success metrics, and coordinates Engineering, AI/ML, Data Science, Security, Design, and client teams. It also embeds healthcare compliance, security, and responsible AI throughout the product lifecycle.

Lead phData’s life sciences commercial strategy and solutions business across market access, pricing, patient services, commercial operations, omnichannel, payer analytics, and gross-to-net. Develop go-to-market offerings, accelerators, proposals, strategic pursuits, thought leadership, and account expansion opportunities. Advise executive clients while partnering with data, engineering, machine learning, and platform teams to create scalable, technically feasible solutions.

Provides strategic finance leadership to venture-backed AI and SaaS startups. Responsibilities include monthly close oversight, budgeting and forecasting, capital planning, treasury management, board reporting, investor updates, fundraising, M&A support, cap table analysis, revenue cycle management, cash flow planning, controls, audit readiness, and advising founders on financial strategy.

Build edge-focused full-stack product experiences integrating machine learning and autonomy for frontline defense users. Collaborate with designers, infrastructure teams, product teams, and ML engineers to create intuitive applications, efficient edge-deployed application stacks, and internal modeling APIs. Develop maintainable software using strong engineering practices, including design documents, code reviews, and style guides.

Design, build, deploy, and optimize scalable AI and machine learning systems using large datasets. Develop predictive models, recommendation systems, personalization engines, forecasting solutions, generative AI applications, and production ML pipelines. Collaborate with data, backend, and product teams to integrate models into applications, while monitoring performance, data quality, drift, reliability, and cost. Establish best practices for evaluation, experimentation, reproducibility, and deployment, and research emerging AI technologies.

Own end-to-end product design for a two-sided affordable housing marketplace, from research and strategy through prototyping, launch, and iteration. Simplify complex workflows, conduct user research, collaborate cross-functionally, design polished Figma interfaces, run experiments, and create AI-powered experiences. Connect design decisions to customer needs, business metrics, and marketplace outcomes.

Leads enterprise product and technology integrations, cross-functional projects, AI and automation initiatives, business analysis, vendor coordination, executive communications, and change adoption. Develops requirements, implementation plans, business cases, risk strategies, and executive reporting while ensuring initiatives meet scope, schedule, compliance, and organizational objectives.