Top Senior Machine Learning Jobs in St. Louis, MO

7 Days AgoSaved
In-Office
St. Louis, MO
105K-124K Annually
Senior level
105K-124K Annually
Senior level
Fintech
Design, build, deploy, monitor, and optimize unattended Power Automate RPA workflows. Collaborate with business and IT partners, ensure compliance and security, document solutions, perform testing and code reviews, support production, and cross-train on Automation Anywhere.
Top Skills: Artificial IntelligenceAutomation AnywhereAzureJavaMachine LearningMicrosoft Power Automate UnattendedOffice 365Power AutomatePower PlatformPythonRpa
Reposted 3 Days AgoSaved
Remote or Hybrid
St. Louis, MO
141K-238K Annually
Senior level
141K-238K Annually
Senior level
Artificial Intelligence • Cloud • Sales • Security • Software • Cybersecurity • Data Privacy
The Staff Machine Learning Engineer will design and build scalable ML systems, mentor engineers, and drive AI strategy at SailPoint, focusing on AI-powered identity security solutions.
Top Skills: AirflowAWSCloudbeesDbtJenkinsPythonPyTorchQlikScikit-LearnSnowflakeSparkSQLTableauTensorFlow
Reposted 9 Days AgoSaved
In-Office
St. Louis, MO
240K-240K Annually
Senior level
240K-240K Annually
Senior level
Financial Services
Oversee a portfolio of AI initiatives, drive strategy and execution, manage vendor relationships, and facilitate change management and adoption of AI tools.
Top Skills: AIData GovernanceMachine Learning
Reposted 10 Days AgoSaved
Hybrid
St. Louis, MO
94K-94K Annually
Senior level
94K-94K Annually
Senior level
Payments
Lead architecture, development, and deployment of scalable AI-driven platforms. Collaborate cross-functionally, set technical strategy and best practices (MLOps, CI/CD, DevOps), ensure data privacy/security, mentor teams, and drive enterprise AI/ML initiatives.
Top Skills: AWSAzureCi/CdComputer VisionDeep LearningDevOpsGCPGenerative AiMachine LearningMlopsMs Sql ServerNlpVisual Studio .Net
Reposted 10 Days AgoSaved
In-Office
St. Louis, MO
139K-212K Annually
Senior level
139K-212K Annually
Senior level
Artificial Intelligence • Big Data • Machine Learning
Lead program management for Public Sector computer vision projects, coordinating engineering, delivery, and analytics to optimize data labeling workflows, improve data quality and throughput, and deliver ML-ready datasets for national security customers.
Top Skills: Computer VisionData AnalyticsData LabelingGenerative AiGeospatial ImageryMachine LearningMl OpsVideo Annotation
Reposted 10 Days AgoSaved
In-Office
St. Louis, MO
206K-257K Annually
Senior level
206K-257K Annually
Senior level
Artificial Intelligence • Big Data • Machine Learning
The Product Manager will architect and manage the Public Sector Data Engine, focusing on ML Ops tools for AI applications while ensuring system integration and collaborating with government stakeholders.
Top Skills: APIsComputer VisionMachine LearningMl OpsSoftware Engineering
10 Hours AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Security
Lead delivery of advanced analytics and investigative support for federal programs. Manage multiple concurrent projects, schedules, costs, risks, personnel, vendors, and stakeholder communications to ensure quality, timely contract-aligned deliverables.
Top Skills: AgileArtificial IntelligenceCloud-Based PlatformsData GovernanceEnterprise Data ManagementFraud AnalyticsGraph AnalyticsInvestigative AnalysisMachine Learning
Reposted 10 Hours AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Payments • Software
The Data Science Manager will lead and mentor a team of data scientists, drive data-driven decision-making across Stripe, and collaborate with various stakeholders. Responsibilities include managing projects, recruiting, and contributing to broader data science initiatives.
Top Skills: Computer ScienceEconomicsEngineeringMachine LearningOperations ResearchStatistics
YesterdaySaved
Remote
St. Louis, MO
Senior level
Senior level
Cloud • Software
Design, build, and operate production AI platform capabilities and agentic workflows. Collaborate on architecture, write production-quality backend code, mentor developers, troubleshoot production issues, and drive adoption of reusable AI frameworks, MLOps practices, and cloud-native intelligent services across a multi-tenant SaaS dental platform.
Top Skills: Amazon BedrockAnthropicAPIsClaude CodeCloud-Native ArchitecturesCursorGithub CopilotLanggraphLlmsMachine LearningMcp ServersOpenaiPythonRetrieval-Augmented Generation (Rag)Semantic SearchVector Databases
YesterdaySaved
Remote
St. Louis, MO
182K-214K Annually
Senior level
182K-214K Annually
Senior level
Big Data • Food • Mobile • Payments
Lead vision, strategy, and roadmap for Fetch's referral growth engine. Own end-to-end referral lifecycle, build incentives, experimentation, AI-driven personalization, and cross-functional initiatives to drive MAU growth and durable network effects.
Top Skills: A/B TestingAIExperimentation FrameworksMachine LearningPersonalization
YesterdaySaved
Remote
St. Louis, MO
Senior level
Senior level
Logistics • Transportation
Embed with customers to discover needs, design and implement production-grade integrations (APIs, data pipelines, event-driven workflows), deploy and troubleshoot solutions, train IT teams, and drive adoption and measurable business outcomes.
Top Skills: Auth0CRMData PipelinesErpEvent-Driven ArchitectureMachine LearningMessage QueuesNode.jsOauth2PythonRest ApisSAMLSQLTmsTypescriptWebhooks
Reposted YesterdaySaved
Remote
St. Louis, MO
150K-175K Annually
Senior level
150K-175K Annually
Senior level
Artificial Intelligence • Software
The Enterprise Account Executive will drive revenue growth by managing complex sales cycles, closing deals with Fortune 500 companies, and understanding both technical and business needs.
Top Skills: AIAPIsInfrastructureMachine Learning
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Reposted 6 Days AgoSaved
Easy Apply
Remote or Hybrid
St. Louis, MO
Easy Apply
243K-286K Annually
Senior level
243K-286K Annually
Senior level
Artificial Intelligence • Cloud • Computer Vision • Hardware • Internet of Things • Software
The Senior Machine Learning Engineer will develop ML APIs, build data pipelines, and collaborate across teams to enhance ML models and applications.
Top Skills: C++DockerGoJavaKubernetesPythonPyTorchScalaSparkTensorFlow
Reposted 6 Days AgoSaved
Remote or Hybrid
St. Louis, MO
122K-160K Annually
Senior level
122K-160K Annually
Senior level
Edtech • Information Technology • Software
The Machine Learning Engineer develops production ML algorithms and recommendation systems, collaborates with teams, and optimizes user experiences.
Top Skills: DockerKubernetesNode.jsPythonTensorFlowTypescript
Reposted YesterdaySaved
Remote
St. Louis, MO
Senior level
Senior level
Artificial Intelligence • Information Technology • Machine Learning • Software • Analytics • Consulting • Financial Services
Lead technical solution development for military and Federal civilian health capture and proposal efforts, ensuring technical compliance and producing quality architecture designs.
Top Skills: AgileAWSAzureData GovernanceData PipelinesDevOpsETLFhirGCPHl7Machine LearningSafe
Reposted YesterdaySaved
Remote
St. Louis, MO
100-120 Hourly
Senior level
100-120 Hourly
Senior level
Artificial Intelligence • HR Tech • Professional Services • Software
Design, implement, and optimize AI-powered solutions to support financial compliance and controls. Monitor GAAP/IFRS adherence, automate controls and reporting, support internal/external audits, and manage complex accounting areas like revenue recognition and lease accounting while collaborating with finance, audit, and technology teams.
Top Skills: AIAutomation ToolsData AnalyticsErpFinancial Reporting ToolsMachine LearningRpa
Reposted YesterdaySaved
Remote
St. Louis, MO
100-120 Hourly
Senior level
100-120 Hourly
Senior level
Artificial Intelligence • HR Tech • Professional Services • Software
Contract role combining actuarial science, risk management, and AI to improve portfolio performance. Responsibilities include loss and combined ratio analysis, portfolio risk assessment, catastrophe and exposure modeling, stress testing, and integrating ML to enhance pricing, reserving, and risk selection while collaborating with underwriting, finance, and product teams.
Top Skills: Catastrophe Modeling ToolsCloud-Based Analytics PlatformsData Visualization ToolsGeospatial DataMachine LearningPythonR
Reposted YesterdaySaved
Remote or Hybrid
St. Louis, MO
Senior level
Senior level
Artificial Intelligence • Software
The Hyperscalers and Commercial Lead will develop technology-driven business strategies, drive customer adoption, and manage end-to-end sales processes while working closely with cross-functional teams.
Top Skills: AIArticul8CRMMachine LearningNvidia Dgx PlatformSaaS
Reposted YesterdaySaved
Remote
St. Louis, MO
180K-230K Annually
Senior level
180K-230K Annually
Senior level
Software
The role focuses on leading editorial efforts to define industry narratives around energy infrastructure, translating regulatory changes into strategic content for executives, and influencing sales and positioning through high-impact communications.
Top Skills: Digital TwinsMachine Learning
Reposted YesterdaySaved
Remote
St. Louis, MO
Senior level
Senior level
Cloud
The Principal Architect will lead AI/ML solutions, mentor teams, and collaborate with clients to design and deliver scalable systems using Google Cloud technologies, ensuring compliance with ethical standards.
Top Skills: AIGCPJaxLangchainLanggraphMachine LearningMlopsPyTorchTpusVertex Ai
Reposted YesterdaySaved
Remote
St. Louis, MO
186K-279K Annually
Senior level
186K-279K Annually
Senior level
Internet of Things • Pharmaceutical
The Director of Statistics leads statistical initiatives in phase 3b/4 and RWE studies, provides expertise in HTA and regulatory compliance, and collaborates with cross-functional teams. Responsibilities include statistical analysis plans, Bayesian methodologies, and mentoring junior staff.
Top Skills: AIBayesian MethodsMachine LearningRSAS
Reposted YesterdaySaved
Remote
St. Louis, MO
130K-140K Annually
Senior level
130K-140K Annually
Senior level
Cloud • Software • Cybersecurity
Develop, deploy, and operationalize analytical and ML/AI models for cybersecurity use cases. Collaborate with product and engineering teams to enable and migrate production workflows, work with databases and data architectures, create visualizations and reports, adopt new cloud orchestration and data virtualization technologies, and mentor junior cyber data scientists.
Top Skills: Artificial IntelligenceCloud Model OrchestrationData Transformation ToolsData VirtualizationMachine LearningOpen-Source FrameworksRelational DatabasesRisk Management Framework (Rmf)
Reposted YesterdaySaved
Remote
St. Louis, MO
150K-200K Annually
Senior level
150K-200K Annually
Senior level
Healthtech • Software
As a Senior Machine Learning Engineer, you will design and implement systems for ML and NLP, optimizing models and tools for Clover's healthcare solutions.
Top Skills: LlmMachine LearningNatural Language ProcessingNumpyPandasPythonPyTorchScikit-LearnTensorFlow
Reposted YesterdaySaved
Remote
St. Louis, MO
Senior level
Senior level
Software
Lead the design, development, and deployment of scalable machine learning and AI systems for enterprise clients, guiding architecture and mentoring engineers.
Top Skills: AIAWSAzureDockerGCPKubernetesMachine LearningPythonPyTorchTensorFlow
Reposted YesterdaySaved
Remote
St. Louis, MO
165K-195K Annually
Senior level
165K-195K Annually
Senior level
Artificial Intelligence • Computer Vision • Software
Senior product engineer owning end-to-end product surfaces for a computer vision platform. Ship features from idea to production, prioritize roadmap, design UX details, integrate APIs, improve annotation and model-assisted labeling, and collaborate with engineering and users to drive product impact.
Top Skills: Computer VisionMachine LearningOpen SourceRest ApiRoboflow
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