Top Senior Machine Learning Jobs in St. Louis, MO

Reposted 2 Days AgoSaved
Remote
St. Louis, MO
210K-260K Annually
Senior level
210K-260K Annually
Senior level
Fintech • Information Technology • Software
Manage a team of data scientists to develop fraud detection models, lead planning and collaboration with leadership, and communicate outcomes effectively while maintaining strong business intuition and technical leadership.
Top Skills: Aws Ec2Aws RdsAws RedshiftAws S3PostgresPython 3
Reposted 25 Days AgoSaved
Easy Apply
Remote
St. Louis, MO
Easy Apply
160K-200K Annually
Senior level
160K-200K Annually
Senior level
Artificial Intelligence • Enterprise Web • Information Technology • Productivity • Sales • Software • Database
The Senior Data Scientist will analyze data to drive product strategy, optimize performance, and support product launches, collaborating with cross-functional teams.
Top Skills: A/B TestingAmplitudeHeapLookerMachine LearningMixpanelPythonRSASSQL
Reposted 3 Days AgoSaved
Easy Apply
Remote
St. Louis, MO
Easy Apply
194K-285K Annually
Senior level
194K-285K Annually
Senior level
Artificial Intelligence • Enterprise Web • Software • Design • Generative AI
The Senior Staff Machine Learning Scientist will lead research initiatives in computer vision and multimodal understanding, develop novel models, and translate research into practical applications while mentoring team members.
Top Skills: PythonPyTorchTensorFlow
4 Days AgoSaved
Easy Apply
In-Office or Remote
St. Louis, MO
Easy Apply
200K-230K Annually
Senior level
200K-230K Annually
Senior level
Artificial Intelligence • Hardware • Healthtech • Software
Lead the Data + ML Platform team to design, build, and operate scalable data and MLOps infrastructure. Drive platform strategy, enable ML experimentation-to-production workflows (model registry, feature stores, drift monitoring, experiment tracking), modernize streaming and batch pipelines, and scale the team while partnering cross-functionally to deliver measurable outcomes.
Top Skills: Batch Data PipelinesDrift MonitoringExperiment TrackingFeature StoreLlmMlopsModel RegistryMultimodal Sensor DataOffline Feature StoreOnline Feature StoreShadow DeploymentsStreaming Data PipelinesTraining Data ManagementVlm
8 Days AgoSaved
In-Office
St. Louis, MO
105K-124K Annually
Senior level
105K-124K Annually
Senior level
Fintech
Design, build, deploy, monitor, and optimize unattended Power Automate RPA workflows. Collaborate with business and IT partners, ensure compliance and security, document solutions, perform testing and code reviews, support production, and cross-train on Automation Anywhere.
Top Skills: Artificial IntelligenceAutomation AnywhereAzureJavaMachine LearningMicrosoft Power Automate UnattendedOffice 365Power AutomatePower PlatformPythonRpa
Reposted 4 Days AgoSaved
Remote or Hybrid
St. Louis, MO
141K-238K Annually
Senior level
141K-238K Annually
Senior level
Artificial Intelligence • Cloud • Sales • Security • Software • Cybersecurity • Data Privacy
The Staff Machine Learning Engineer will design and build scalable ML systems, mentor engineers, and drive AI strategy at SailPoint, focusing on AI-powered identity security solutions.
Top Skills: AirflowAWSCloudbeesDbtJenkinsPythonPyTorchQlikScikit-LearnSnowflakeSparkSQLTableauTensorFlow
Reposted An Hour AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Healthtech • Professional Services • Biotech • Pharmaceutical
The Senior Data Scientist will manage data collection, design study protocols, train juniors, lead report development, and support innovative analytics tools.
Top Skills: Data AnalysisMachine LearningProject Management FrameworksStatistical Analysis
Reposted An Hour AgoSaved
In-Office or Remote
St. Louis, MO
Senior level
Senior level
Travel
The Senior Product Manager will lead the integration of airline and third-party partners, optimize supply metrics, and leverage AI for automation. Responsibilities include managing APIs, collaborating with engineering, and improving the booking experience.
Top Skills: AIAPIsMachine Learning
Reposted An Hour AgoSaved
Remote
St. Louis, MO
257K-402K Annually
Senior level
257K-402K Annually
Senior level
Robotics
The Director of AI will lead AI and machine learning initiatives, develop AI architecture for humanoid robots, oversee production-ready AI systems, and manage team growth and budget.
Top Skills: AIComputer VisionIsaac SimMachine LearningMlopsMujocoNatural Language ProcessingPhysics-Based SimulationReinforcement LearningRobotics
Reposted An Hour AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Machine Learning • Software
The Senior Machine Learning Engineer will design, prototype, build AI systems, evaluate ML models, and improve Vectara's AI Agents with a focus on reliability and performance.
Top Skills: Deep LearningMachine LearningNatural Language ProcessingPandasPythonPyTorchRetrieval-Augmented GenerationTransformers
Reposted An Hour AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Fintech • Software • Financial Services
As a Senior Machine Learning Engineer, you'll build and deploy ML models for risk and fraud detection, leading technical efforts and collaborating cross-functionally.
Top Skills: Machine LearningPythonSQL
Reposted An Hour AgoSaved
Remote
St. Louis, MO
181K-475K Annually
Senior level
181K-475K Annually
Senior level
Fintech • Healthtech • Analytics
The VP of Sales will drive enterprise adoption of AI-powered healthcare software, engage with stakeholders, and shape go-to-market strategies for new AI products.
Top Skills: AIHealthcare SoftwareMachine Learning
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Reposted An Hour AgoSaved
Remote
St. Louis, MO
225K-255K Annually
Senior level
225K-255K Annually
Senior level
Security
As a Machine Learning Engineer, you'll design, build, and maintain models to detect security threats, ensuring model efficiency and aligning initiatives with business goals.
Top Skills: AWSDockerGCPGenerative AiKubernetesLlmsMachine LearningPandasPythonScikit
Reposted An Hour AgoSaved
Remote
St. Louis, MO
210K-300K Annually
Senior level
210K-300K Annually
Senior level
eCommerce • Retail • Software
Lead the vision and strategy for the Commerce Intelligence Platform, transforming data assets into scalable, revenue-generating products, fostering cross-functional collaboration and driving market growth.
Top Skills: AIData PlatformsMachine LearningProduct Management
Reposted An Hour AgoSaved
Remote
St. Louis, MO
173K-375K Annually
Senior level
173K-375K Annually
Senior level
AdTech • Digital Media • Information Technology • Other
Lead Yahoo's Data Activation product area: define vision and strategy, partner with Data Science and Engineering, drive cross-vertical data activation initiatives, deliver measurable business impact, and mentor/manage product teams to execute on audience, personalization, and targeting use cases.
Top Skills: AgileAIGoogle Cloud PlatformMachine LearningScrumSQL
Reposted An Hour AgoSaved
Remote or Hybrid
St. Louis, MO
240K-330K Annually
Senior level
240K-330K Annually
Senior level
Artificial Intelligence • Automotive • Machine Learning • Transportation
This role leads the ML Acceleration team, focusing on enhancing ML model training efficiency and team management, while driving technical strategy and collaboration.
Top Skills: AWSAzureC++GCPJaxMachine LearningMl FrameworksPythonPyTorch
Reposted An Hour AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
AdTech
Lead the Performance ML team at MNTN, driving strategy and deployment of predictive models for ad technology, while managing, mentoring, and scaling engineering teams.
Top Skills: Data ScienceGoogle Cloud PlatformMachine Learning
Reposted 11 Days AgoSaved
Hybrid
St. Louis, MO
94K-94K Annually
Senior level
94K-94K Annually
Senior level
Payments
Lead architecture, development, and deployment of scalable AI-driven platforms. Collaborate cross-functionally, set technical strategy and best practices (MLOps, CI/CD, DevOps), ensure data privacy/security, mentor teams, and drive enterprise AI/ML initiatives.
Top Skills: AWSAzureCi/CdComputer VisionDeep LearningDevOpsGCPGenerative AiMachine LearningMlopsMs Sql ServerNlpVisual Studio .Net
Reposted 11 Days AgoSaved
In-Office
St. Louis, MO
139K-212K Annually
Senior level
139K-212K Annually
Senior level
Artificial Intelligence • Big Data • Machine Learning
Lead program management for Public Sector computer vision projects, coordinating engineering, delivery, and analytics to optimize data labeling workflows, improve data quality and throughput, and deliver ML-ready datasets for national security customers.
Top Skills: Computer VisionData AnalyticsData LabelingGenerative AiGeospatial ImageryMachine LearningMl OpsVideo Annotation
YesterdaySaved
Remote
St. Louis, MO
Senior level
Senior level
Security
Lead delivery of advanced analytics and investigative support for federal programs. Manage multiple concurrent projects, schedules, costs, risks, personnel, vendors, and stakeholder communications to ensure quality, timely contract-aligned deliverables.
Top Skills: AgileArtificial IntelligenceCloud-Based PlatformsData GovernanceEnterprise Data ManagementFraud AnalyticsGraph AnalyticsInvestigative AnalysisMachine Learning
Reposted YesterdaySaved
Remote
St. Louis, MO
Senior level
Senior level
Payments • Software
The Data Science Manager will lead and mentor a team of data scientists, drive data-driven decision-making across Stripe, and collaborate with various stakeholders. Responsibilities include managing projects, recruiting, and contributing to broader data science initiatives.
Top Skills: Computer ScienceEconomicsEngineeringMachine LearningOperations ResearchStatistics
2 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Cloud • Software
Design, build, and operate production AI platform capabilities and agentic workflows. Collaborate on architecture, write production-quality backend code, mentor developers, troubleshoot production issues, and drive adoption of reusable AI frameworks, MLOps practices, and cloud-native intelligent services across a multi-tenant SaaS dental platform.
Top Skills: Amazon BedrockAnthropicAPIsClaude CodeCloud-Native ArchitecturesCursorGithub CopilotLanggraphLlmsMachine LearningMcp ServersOpenaiPythonRetrieval-Augmented Generation (Rag)Semantic SearchVector Databases
2 Days AgoSaved
Remote
St. Louis, MO
182K-214K Annually
Senior level
182K-214K Annually
Senior level
Big Data • Food • Mobile • Payments
Lead vision, strategy, and roadmap for Fetch's referral growth engine. Own end-to-end referral lifecycle, build incentives, experimentation, AI-driven personalization, and cross-functional initiatives to drive MAU growth and durable network effects.
Top Skills: A/B TestingAIExperimentation FrameworksMachine LearningPersonalization
2 Days AgoSaved
Remote
St. Louis, MO
Senior level
Senior level
Logistics • Transportation
Embed with customers to discover needs, design and implement production-grade integrations (APIs, data pipelines, event-driven workflows), deploy and troubleshoot solutions, train IT teams, and drive adoption and measurable business outcomes.
Top Skills: Auth0CRMData PipelinesErpEvent-Driven ArchitectureMachine LearningMessage QueuesNode.jsOauth2PythonRest ApisSAMLSQLTmsTypescriptWebhooks
Reposted 2 Days AgoSaved
Remote
St. Louis, MO
150K-175K Annually
Senior level
150K-175K Annually
Senior level
Artificial Intelligence • Software
The Enterprise Account Executive will drive revenue growth by managing complex sales cycles, closing deals with Fortune 500 companies, and understanding both technical and business needs.
Top Skills: AIAPIsInfrastructureMachine Learning
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