Top Senior Machine Learning Jobs in St. Louis, MO

Own and develop SandboxAQ’s intellectual property function, including patent portfolio strategy, invention harvesting, prosecution, lifecycle management, outside counsel oversight, freedom-to-operate analyses, trademark clearance, and trade secret programs. Partner with scientists, engineers, and business teams to protect innovations, inform product strategy, support transactions, and build scalable IP processes in a fast-growing AI-focused company.

Manage paid media strategies and campaigns across search, social, display, and programmatic channels. Advise clients using integrated paid, organic, and analytics data; oversee campaign performance, keyword research, ad copy, landing page recommendations, and presentations. Build client relationships, mentor account associates, collaborate with SEO and data teams, and use AI to improve workflows and outcomes.

Develop and lead paid media strategies across search, social, display, and programmatic channels. Manage campaign strategy, performance analysis, testing, optimization, and integrated paid and organic recommendations. Consult with clients, present results, build relationships, mentor account associates, and identify data-driven growth opportunities. Use AI tools to improve workflows and contribute insights across the team.

Build and lead Nebius’s federal affairs function in Washington, D.C. Develop policy strategy across AI regulation, trade, energy, infrastructure, and national security; establish bipartisan relationships with Congress and executive agencies; represent the company in federal initiatives and coalitions; assess regulatory risks; coordinate with legal, communications, and infrastructure teams; manage outside lobbying partners; and hire staff as the function scales.

Lead research, architecture, and production deployment of large-scale algorithms for budget pacing, bid optimization, and marketplace balancing in Yahoo’s DSP. Apply control theory, optimization, and machine learning to real-time systems, while establishing AI-augmented research and engineering workflows. Own multi-quarter initiatives, define evaluation frameworks, guide technical strategy, collaborate with product and engineering leadership, mentor scientists and engineers, and communicate complex research and architectural decisions to executives.

Owns end-to-end development of datasets, reinforcement learning environments, and evaluations for coding agents and software engineering models. Leads engineers, researchers, QA professionals, and data creators; establishes quality processes, pipelines, validation, and review workflows. Collaborates directly with frontier AI labs, fine-tunes models, builds benchmarks, develops automation and internal tools, and supports customer-facing enablement. The role combines hands-on technical leadership, engineering management, operational execution, research, and industry thought leadership.

Lead the strategy, design, deployment, and scale-up of AI-powered health products across the Global South. Own product roadmaps, execution, government-system integration, stakeholder adoption, partnerships, grant development, and portfolio expansion. Collaborate with engineering, machine learning, program, and domain teams to deliver sustainable, measurable public-health impact.

Performs advanced physical and remote insurance premium audits for business clients. Reviews business records, interviews owners and managers, investigates exposures, documents findings, prepares written audit reports, schedules assignments, communicates results, and submits completed work for quality review. The auditor must manage deadlines independently, correct returned audits, maintain accurate records, and use Microsoft Office applications. This remote role requires reliable transportation, a valid driver’s license, strong analytical and communication skills, and at least five years of premium insurance auditing experience.

Leads the company’s adoption of AI, analytics, automation, and business intelligence. Builds AI-powered workflows, Excel solutions, natural-language data interfaces, dashboards, forecasts, predictive analytics, and automated reporting using Snowflake, SQL, Tableau, and related tools. Partners across business functions to identify opportunities, improve data quality, automate repetitive processes, and deliver scalable decision-support solutions. Establishes responsible AI practices and advances an AI-first analytics culture.

Design and deploy machine learning models for financial document processing, optimize large language models, collaborate with cross-functional teams, and guide junior peers in a fast-paced environment.

Lead the Data Sources product roadmap for document parsing, fraud detection, and bank aggregation. Drive metrics (parse accuracy, fraud catch rate, connection success, SLAs), write specs, engage clients, mentor PMs/engineers, and represent the platform externally. Prioritize document types, extraction models, reliability, and scalability to improve conversion, client satisfaction, and operational efficiency across mortgage, tenant screening, and government use cases.

Lead end-to-end ML systems for identity verification, including document authenticity, face match, liveness and deepfake detection. Build GNN-based identity graphs, behavioral/device-intelligence models, vendor benchmarking/evaluation, and production enforcement. Mentor engineers and align ML architecture with Product, Compliance, Risk, and Security stakeholders.

Lead design and implementation of scalable data models and analytical tooling for Consumer Product. Partner cross-functionally to translate business needs into reliable SQL/Python data products, dashboards, and automated pipelines using engineering best practices (CI/CD, testing, version control, monitoring). Drive data-informed strategy and manage long-term infrastructure while supporting ad hoc requests.

As a Senior Machine Learning Engineer, you'll build and deploy ML models for risk and fraud detection, leading technical efforts and collaborating cross-functionally.

The Director of AI will lead AI and machine learning initiatives, develop AI architecture for humanoid robots, oversee production-ready AI systems, and manage team growth and budget.

Develop and expand software products and platforms across backend, frontend, cloud, AI, and machine learning systems. Build efficient, reliable, and testable code; collaborate with business partners to launch features; influence product and engineering decisions; mentor team members; and help shape team culture and product vision in an agile environment.

Build and productionize customer-facing data and AI solutions on the Databricks platform. Own architecture and design decisions, develop end-to-end data pipelines and applications, integrate machine learning models, and guide enterprise customers through implementation and adoption. Collaborate with engineering, product, support, project managers, and customer stakeholders while delivering projects, documenting solutions, resolving issues, and creating reusable frameworks. Travel to customers approximately 20% of the time.

Leads the engineering strategy, architecture, development, operations, and continuous improvement of an enterprise agentic AI foundation. Establishes scalable engineering standards, operating models, governance, and reusable platform services that enable AI products and intelligent workflows. Partners with product, data, infrastructure, security, and business teams to modernize existing systems, guide cross-functional delivery, monitor operations, and communicate priorities, risks, and investment needs to senior leaders. Manages and develops product or engineering leaders while driving measurable business value.

Designs, evaluates, and improves ranking and recommendation systems through experimentation, feature engineering, and production machine learning. Builds reliable data and feature pipelines, incorporates multimodal signals, manages uncertainty, calibration, and model drift, and monitors system performance. Partners cross-functionally with Engineering, Product, Business, and Analytics to deliver scalable, latency-sensitive solutions with measurable business impact.

The Senior Machine Learning Engineer will develop core ML models, manage data pipelines, and collaborate with stakeholders to deliver scalable ML solutions.

Design, implement, and optimize AI-powered solutions to support financial compliance and controls. Monitor GAAP/IFRS adherence, automate controls and reporting, support internal/external audits, and manage complex accounting areas like revenue recognition and lease accounting while collaborating with finance, audit, and technology teams.

Contract role combining actuarial science, risk management, and AI to improve portfolio performance. Responsibilities include loss and combined ratio analysis, portfolio risk assessment, catastrophe and exposure modeling, stress testing, and integrating ML to enhance pricing, reserving, and risk selection while collaborating with underwriting, finance, and product teams.

Lead vision, strategy, and roadmap for Fetch's referral growth engine. Own end-to-end referral lifecycle, build incentives, experimentation, AI-driven personalization, and cross-functional initiatives to drive MAU growth and durable network effects.

Senior product engineer owning end-to-end product surfaces for a computer vision platform. Ship features from idea to production, prioritize roadmap, design UX details, integrate APIs, improve annotation and model-assisted labeling, and collaborate with engineering and users to drive product impact.

Design, develop, and evaluate conversational AI agents and generative AI products. Collaborate with AI scientists, ML engineers, and Responsible AI/Model Validation teams to ensure state-of-the-art, ethical solutions and support deployment and integration of conversational systems.