Top Senior Machine Learning Jobs in St. Louis, MO

The Senior ML Engineer will develop and deploy full-stack AI solutions, manage LLM integration, and collaborate closely with defense clients to enhance real-world applications in secure environments.

Lead and execute ML/AI strategy, design and deploy production-grade ML and GenAI solutions, mentor MLEs, collaborate with cross-functional teams, and build scalable, secure ML/LLM platforms and inference pipelines to drive business impact.

Build and productionize AI systems for logistics: multi-agent copilots, forecasting/optimization models, evaluation and observability, continuous learning loops, and operational reliability. Mentor engineers and make build-vs-rule tradeoffs while shipping high-impact ML services.

As a Senior MLOps Engineer, you will manage production ML systems, define lifecycle strategies, optimize ML pipelines, and collaborate with cross-functional teams to enhance ML operations.

The job involves building responsive web dashboards, advanced data visualizations, and analytics tools for unmanned aircraft systems, requiring a deep understanding of UI/UX design and data presentation.

Design and maintain datasets, build and evaluate domain-specific ML and vision-language models for real-time privileged access threat detection; deploy and optimize Python/Docker inference services integrated with WebSocket/WebRTC and protocol-level interfaces; monitor and document production models.

Design and implement AI-powered data pipelines and LLM-based mapping to parse, normalize, and validate structured and unstructured data. Build mapping logic, ingestion templates, and load-ready outputs; integrate ML/AI solutions with enterprise systems (APIs, databases, Azure); validate accuracy with stakeholders; document for scalability and production readiness while reducing manual mapping and improving data quality.

Responsible for fine-tuning state-of-the-art LLMs, optimizing models for deployment, and driving AI architectural decisions. Collaborate with cross-functional teams to develop impactful AI products.

Design, build, and own production ML and LLM-driven features (RAG, prompt engineering, fine-tuning, semantic search). Write maintainable code, create design docs, troubleshoot issues, collaborate with product/design, and participate in Agile development. Work with Python/Java/JavaScript, ML frameworks, and cloud/container technologies.

As a Staff Machine Learning Research Scientist, you will lead ML research, develop evaluation frameworks, mentor researchers, and collaborate on clinical AI solutions.

Lead a team of machine learning data scientists, overseeing model development for fraud detection and risk assessment, and ensuring quality throughout the model lifecycle while mentoring the team.

Design, build, deploy, and operate production-grade AI/ML and LLM systems (including RAG and agentic pipelines). Integrate AI capabilities with product workflows, run evaluation and monitoring, optimize model and system performance, and apply strong engineering practices (testing, CI/CD, versioning).

Design and implement production ML features, close behavior gaps with common frameworks, investigate divergences, improve performance and stability, and document designs and tests for geospatial and large-scale ML workflows.

Lead design, development, and delivery of ML, DL, and Generative AI systems for production. Apply prescriptive analytics, optimization, recommendation, and reinforcement learning. Build and evaluate models, run experiments, develop prototypes, benchmark methods, and collaborate with business partners to translate data into actionable recommendations and influence strategy.

Design, develop, and deploy end-to-end machine learning models using statistical and ML algorithms. Prepare and enrich data, implement scalable PySpark/Databricks solutions, and collaborate with product and engineering to create personalized customer experiences and actionable insights.

Design, develop, fine-tune, and deploy generative AI models (GANs, VAEs, transformers). Collaborate with cross-functional teams, troubleshoot model issues, document work, and communicate technical concepts to non-technical stakeholders while staying current on research.

Design, develop, fine-tune, and deploy generative AI models using deep learning and transformer architectures. Collaborate cross-functionally, troubleshoot model issues, optimize performance, document work, and communicate technical concepts to non-technical stakeholders.

Design, build, and deploy production-grade ML and AI systems end-to-end, combining classical ML, deep learning, and LLM/agentic integrations. Implement MLOps, monitoring, CI/CD, model serving, vector search/RAG pipelines, and scalable APIs; mentor engineers and drive engineering best practices.

Design, build, and deploy production Generative AI applications: orchestrate multi-agent workflows, implement advanced RAG with vector DBs, integrate and fine-tune LLMs, develop scalable FastAPI/async backends, containerize with Docker, and optimize GenAI systems for latency, cost, and reliability.

Build and scale production Generative AI applications: design multi-agent systems and LangGraph workflows, implement advanced RAG with LlamaIndex and vector DBs, integrate and fine-tune various LLMs, and deploy containerized FastAPI services with monitoring, CI/CD, and performance/cost optimizations.

Design, build, and deploy production-grade generative AI applications: orchestrate multi-agent systems, implement advanced RAG with vector DBs, fine-tune and host LLMs, optimize GenAI workflows, and deliver scalable FastAPI-based backend services with Docker and monitoring.

Design, build, and scale production Generative AI systems: multi-agent orchestration, advanced RAG with vector databases, LLM integration and fine-tuning, scalable FastAPI backends, Dockerized deployment, monitoring, and GenAI optimization for latency, cost, and reliability.

Lead architecture, design, and delivery of Generative AI and ML solutions. Build scalable ML pipelines, LLM and RAG-based applications, vector DB integrations, and agent workflows. Drive MLOps, CI/CD, observability, security, and enterprise model orchestration. Provide technical leadership, mentor engineers, run Agile development, and shape AI strategy through POCs and platform innovation.

Design, build, and productionize generative AI solutions: advanced Python development, LLM prompt engineering and fine-tuning, agent frameworks, RAG pipelines with vector DBs, API and cloud deployment, MLOps/LLMOps, model evaluation and Responsible AI practices, and translate business needs into scalable AI applications.

Design, build, and scale production Generative AI applications: multi-agent systems, advanced RAG pipelines, LLM integration and fine-tuning, scalable FastAPI backends, vector search, monitoring, and Dockerized deployments.