Top Senior Data Science Jobs in St. Louis, MO

Lead end-to-end machine learning and advanced analytics projects: frame problems, build and deploy predictive/prescriptive models, design ETL pipelines, create dashboards and A/B test metrics, and deliver actionable insights to business stakeholders to improve fleet, pricing, and ridesharing products.

Lead end-to-end development of fraud and risk ML systems: define problems, engineer features, build and evaluate models, collaborate with product and engineering, deploy with ML engineers, and monitor production performance to detect drift and trigger retraining.

As a Staff Data Scientist, you will lead initiatives to build and optimize machine learning models, collaborate across departments, and solve complex business problems using data.

As a Data Scientist, you will build predictive models, develop software tools, and analyze geoscientific data to support mineral exploration and discovery.

As a Data Scientist, you will develop predictive models, analyze geoscientific data, and collaborate with geoscientists to improve mineral exploration efforts.

Owns the end-to-end development of cybersecurity vulnerability and exploit prediction models, including problem framing, feature engineering, training, evaluation, deployment, calibration, monitoring, and drift detection. The role addresses extreme class imbalance, hierarchical modeling, cold-start customers, and uncertainty quantification. It also requires explaining model outputs to security executives, publishing methodologies and benchmarks, and partnering with engineering to deploy reliable production systems.

Provides biostatistical data science and analytics support for clinical development and evidence generation. Collaborates with biostatistics, data management, clinical development, and medical affairs teams; applies statistics, mathematics, AI, and innovative technologies to clinical trial and real-world data. Contributes to clinical trial design, statistical analysis plans, clinical study reports, publications, and protocol development while following ICH and FDA guidelines.

Own end-to-end data science for a priority vertical (starting with Insurance): frame business problems, build and validate models, partner with ML engineering for deployment, monitor live ROAS performance, and drive measurable revenue and lead quality improvements.

Lead end-to-end data science projects including predictive modeling, algorithm design, and data pipelines. Build campaign-focused models (turnout, partisanship), perform exploration and visualization, translate insights into memos/presentations, collaborate with engineering to productionize models, mentor junior data scientists, and prototype emerging AI solutions for product impact.

The Senior Data Scientist will lead innovative data science efforts, leveraging advanced analytics, visualization, and insights from complex datasets to boost productivity.

Lead predictive modeling and causal inference initiatives for clients, developing models from exploratory analysis through production deployment, monitoring, and retraining. Apply GLMs, econometric methods, uplift modeling, propensity methods, and deep-learning forecasting. Process large-scale data with SQL and Spark, build models in Python, improve production reliability, and communicate findings to technical and business stakeholders in a consulting environment.

Build marketing data science models and decision systems for spend allocation, channel measurement, forecasting, experimentation, and growth optimization. Unify marketing, retail, revenue, and product data; develop dashboards and analytical products; apply AI/ML and causal inference; and translate complex analysis into actionable recommendations for executives and cross-functional teams. The role also includes improving data quality, mentoring, documentation, and technical leadership.

Lead data science work embedded in the newsroom: identify high-impact problems, build and productionize predictive and explanatory models, own core metrics/measurement, apply causal inference and experimentation, translate findings for senior stakeholders, and mentor junior data team members to improve analytic standards and adoption.

Design and implement advanced ML models for real-time forecasting and decision support, ensure data provenance and lineage, integrate federated geospatial and multi-format data, produce ROM and quarterly cost/resource reports, and apply Agile sprint practices to deliver mission-aligned analytics for DoD/IC customers.

As a Senior Data Scientist at Yahoo Mail, you will enhance user growth strategies via product innovation, overseeing research projects and analytics.

Lead development of scalable analytic solutions that transform complex intelligence data into actionable insights. Design and implement data pipelines, automation, data models, visualizations, and production-ready Python tools. Provide technical leadership, rapidly prototype solutions, and collaborate with multidisciplinary IC teams to modernize analytic workflows and support operational decision-making.

Design, develop, and deploy ML models and data pipelines on large structured and unstructured datasets for geospatial intelligence. Build visualizations, integrate analytics with program systems, evaluate model performance, and mentor mid-level data scientists while collaborating with mission analysts to deliver production capabilities.

Build, ship, and own end-to-end ML models for vendor matching, order routing, and supply-chain optimization. Partner with data engineering to productionize models, quantify impact, document work, and implement decision logic components toward agentic AI in a fast-moving healthcare startup environment.

Lead development of time-series and econometric models (ARIMA, VAR, state-space, WLS, panel data) and Bayesian probabilistic frameworks. Use causal inference and stochastic processes to produce actionable insights, work with large datasets on Databricks, communicate results to stakeholders, and mentor junior team members.

Lead advanced analytics and ML projects: perform EDA, feature engineering, statistical modeling, and build/optimize production ML and Generative AI solutions (LLMs, embeddings, RAG). Collaborate with engineering and MLOps to deploy and monitor models, create visualizations and dashboards, translate insights for stakeholders, and mentor junior team members.

Design, build, and deploy production-grade generative AI applications: orchestrate multi-agent systems, implement advanced RAG with vector DBs, fine-tune and host LLMs, optimize GenAI workflows, and deliver scalable FastAPI-based backend services with Docker and monitoring.

Design, build, and deploy production generative AI applications: orchestrate multi-agent workflows, implement advanced RAG with vector databases, integrate/benchmark LLMs, fine-tune models, and deploy scalable FastAPI-based services with monitoring, CI/CD, and Dockerized production pipelines.

Design, build, and scale production Generative AI systems: multi-agent orchestration, advanced RAG with vector databases, LLM integration and fine-tuning, scalable FastAPI backends, Dockerized deployment, monitoring, and GenAI optimization for latency, cost, and reliability.

Design, build, and deploy production-grade generative AI systems: multi-agent orchestration, advanced RAG with vector databases, integrate/swap LLMs, fine-tune models, optimize prompts and latency, and containerize services with monitoring and CI/CD.

Build, optimize, and scale production Generative AI applications. Design multi-agent systems and LangGraph workflows, implement advanced RAG with LlamaIndex and vector DBs, fine-tune and deploy LLMs, and create high-performance FastAPI async backends. Improve latency, cost, and reliability, containerize services with Docker, and manage monitoring, API security, and CI/CD for ML deployments.