Top Senior Python Jobs in San Diego, CA

Individual contributor systems engineer working on aerospace programs: develop and manage requirements, define interfaces, perform analysis, support integration/testing, maintain systems engineering artifacts, coordinate IPTs, use tools like JIRA and DOORS, and support verification/validation and MBSE efforts.

Design, model, and integrate optical components and lenses for survivability systems. Perform raytrace-based optical design, simulate infrared/visual signatures, build and test hardware in lab and flight, collaborate in IPTs, support requirements, and meet customer goals while maintaining required security clearances.

Develop, integrate, test and maintain desktop/web applications and Java microservices; build and maintain CI/CD pipelines; collaborate with SW, HW and test teams; identify technical risks and report to leadership; work in an Agile, process-oriented environment. On-site in San Diego, requires Top Secret clearance and up to 25% travel.

Design, develop, and maintain enterprise-level toolsets to exploit large operational data sets. Build CI/CD pipelines, collaborate across engineering disciplines (Cloud, Networking, DevSecOps, Test), perform data analysis/predictive trending (including AI/ML), manage databases and containers, interpret ICDs, and support mission-critical, on-site defense systems requiring high security clearance.

The role involves designing, developing, and supporting software for complex electro-mechanical systems in semiconductor manufacturing. Responsibilities include full lifecycle development, troubleshooting, and collaboration across teams.

Lead development and implementation of automated test strategies, frameworks, and test environments for the eLxr Linux distribution. Design, integrate, and verify tests for safety-critical embedded and enterprise systems, mentor engineers, improve tooling and workflows, and collaborate with product and global engineering teams to deliver scalable, high-quality solutions.

Manage and automate enterprise Linux/Unix platforms across on-prem and hybrid VMware environments. Ensure availability, security compliance (SOX/FFIEC), perform patching, tuning, incident (P1/P2) response and RCA. Build Puppet modules for provisioning and drift remediation, script with Bash/Python, support backup/DR (Zerto), and execute changes via ServiceNow while maintaining runbooks and audit-ready documentation.

Lead design, implementation, and operation of large-scale, low-latency distributed data platforms and stream processing. Own RTAP architecture, build/optimize services (Flink, Spark, ClickHouse, Druid), integrate batch/stream lakehouse patterns, apply AI tooling to automate platform workflows, mentor engineers, and lead production incident response and reliability improvements.

Design and maintain end-to-end computer system architectures for defense programs. Integrate emerging technologies, implement engineering changes, configure networks, apply STIGs, support labs, and coordinate with peers and government engineers. Full on-site role with occasional travel.

Design, implement, and deliver enterprise Java/JEE solutions and GUIs in an Agile environment. Collaborate with systems engineering, DevSecOps, test automation, and cloud teams across the SDLC. Develop microservices and SOA-based systems, use OOP and design patterns, integrate web services/JMS/XML technologies, and support build/test/release. Must work on-site and meet government security and SAP access requirements.

The Software Engineer will focus on data quality engineering and functional integration, working within an agile team to manage and write test cases based on a large data schema.

The DevOps Consultant will design, implement, and support software applications, manage deployments, and collaborate with engineering teams, requiring strong expertise in automation tools and programming languages.

This role involves ETL testing, working with large data schemas, writing test cases, and engaging in agile project work. Requires strong SQL and scripting skills, along with effective communication and flexibility.

The Senior SoC STA Engineer is responsible for chip-level timing sign-off, developing SDC constraints, and driving timing closure while collaborating with cross-functional teams for successful tape-outs.

The Senior Staff/Principal Engineer will lead digital SoC design and verification, work on product specifications, and collaborate with cross-functional teams.

The Java - Scala Architect will need to program in Java and Scala, manage Apache Spark technologies, and work with NoSQL systems. Additional experience with Hadoop, web services, and data pipeline building is preferred.

Serve as a field survivability engineer: coordinate with designers, develop and integrate low-detectability technologies, plan and execute RCS/RF tests, analyze test data, recommend material/design changes, and coordinate supplier implementation and testing. Role requires significant travel and high-level security clearance.

Technical owner for characterization, qualification, and reliability testing of photonic components and modules. Design and build test setups, execute DOE-driven experiments, measure optical metrics (power, phase noise, RIN, nonlinearity, beam parameters), run EVT/DVT/PVT verification, perform life testing and failure analysis, generate lab-quality data and engineering reports, and build automated test sequences using Python/LabVIEW/MATLAB to drive product development and production readiness.

The Lead Systems Engineer manages the Waveform System Team, conducts systems analysis, integration and test for wireless communication technologies, and ensures staff training and efficient verification.

Design, install, configure, and operate enterprise and cloud network infrastructure using Terraform, Kubernetes networking, and Zero Trust principles. Ensure cyber compliance, troubleshoot complex networking issues, and support system installs, tests, and demos. Collaborate in Agile/DevSecOps environments and travel occasionally for deployments and support.

Design and implement modern frontend features and UI for an AI-native ERP using Next.js, React, and TailwindCSS. Build structured chat interfaces, real-time dashboards and tables, integrate GraphQL and client-side state, support streaming updates and collaborative UX, and partner with design and product to optimize performance, accessibility, and developer velocity.

Design and implement backend services in Python with PostgreSQL, expose GraphQL APIs for AI agents and real-time frontends, optimize DB performance, contribute to CI/CD and Docker deployments, and enable real-time orchestration across human and AI agents.

Build and operate GovCloud production infrastructure and Kubernetes clusters, own GitOps CI/CD, observability, security/compliance (SOC2/CMMC/FedRAMP), contribute backend code (Python/TypeScript), and improve developer experience and resilience.

The Optical Engineer will execute complex engineering tasks, mentor junior engineers, and ensure the accuracy of execution schedule and data quality while engaging with team members and leadership.

Design, build, and operate backend services and APIs that deliver real-time GNSS/RTK corrections at low latency and high availability. Own ingestion, processing, distribution, observability, and testing of distributed systems while collaborating with cross-functional teams and responding to customer needs. Focus on scalability, reliability, performance, and production readiness for a large device fleet.