Top Senior Machine Learning Jobs in Indianapolis, IN

Reposted 3 Days AgoSaved
Remote
Indianapolis, IN
200K-250K Annually
Senior level
200K-250K Annually
Senior level
Artificial Intelligence • eCommerce • Software
As a Senior MLOps Engineer, you will manage production ML systems, define lifecycle strategies, optimize ML pipelines, and collaborate with cross-functional teams to enhance ML operations.
Top Skills: AWSAzureCi/CdGCPPythonPyTorchTensorFlow
Reposted 3 Days AgoSaved
Remote
Indianapolis, IN
Senior level
Senior level
Internet of Things
Build and productionize AI systems for logistics: multi-agent copilots, forecasting/optimization models, evaluation and observability, continuous learning loops, and operational reliability. Mentor engineers and make build-vs-rule tradeoffs while shipping high-impact ML services.
Top Skills: Amazon BedrockAnthropicAzure OpenaiBrowser AutomationDocument UnderstandingFastapiFeature StoresLangchainLanggraphMcpMlopsMulti-Agent OrchestrationOpenaiPythonRag (Retrieval-Augmented Generation)Streaming SystemsTool/Function-Calling
Reposted 4 Days AgoSaved
Remote
Indianapolis, IN
150K-269K Annually
Senior level
150K-269K Annually
Senior level
Cloud • Information Technology • Insurance • Software • Analytics
The role involves defining and refining Guidewire's AI narrative, crafting audience-specific messages, leading competitive positioning, and creating technical marketing assets to convey the value of AI-driven solutions in the P&C insurance sector.
Top Skills: Agent StudioAIAPIsCloud PlatformsData GovernanceGenerative AiLlmopsMlMlopsOrchestration FrameworksSdksVector Stores
4 Days AgoSaved
Remote
Indianapolis, IN
466K-750K Annually
Senior level
466K-750K Annually
Senior level
News + Entertainment
Lead ML initiatives to improve Sales productivity and automation: define roadmap, design and deploy production ML models and AI agents, build measurement pipelines with analytics engineers, iterate from performance and seller feedback, and act as senior technical partner across product, engineering, and Sales to drive measurable revenue impact.
Top Skills: PythonSQL
4 Days AgoSaved
Remote
Indianapolis, IN
600K-1M Annually
Senior level
600K-1M Annually
Senior level
News + Entertainment
Lead ML technical strategy for Live Ads, designing and deploying forecasting, targeting, bidding, auction, and yield-optimization models. Build and evaluate large-scale production ML systems, create online/offline evaluation frameworks, partner with product to set objectives and trade-offs, and communicate results to stakeholders and leadership.
Top Skills: JavaPythonScala
4 Days AgoSaved
Remote
Indianapolis, IN
466K-750K Annually
Senior level
466K-750K Annually
Senior level
News + Entertainment
Design and execute ML research and end-to-end model development for generative and summary-generation systems. Lead rigorous experiments, translate findings for stakeholders, partner with engineers to deploy models, track state-of-the-art advances, and define roadmaps to improve promotional writing and discovery for members.
Top Skills: Deep LearningDiffusion ModelsLarge Language Models (Llms)Llm Post-Training ApproachesNatural Language Processing (Nlp)PythonPyTorchTensorFlow
4 Days AgoSaved
Remote
Indianapolis, IN
466K-750K Annually
Senior level
466K-750K Annually
Senior level
News + Entertainment
Design, prototype, and iterate supervised ML models to predict ad campaign delivery outcomes (reach, frequency, delivery risk). Engineer reusable features from ad-serving logs, build evaluation frameworks, prioritize model explainability, and partner with ML engineers and cross-functional teams to deploy and monitor models at scale.
Top Skills: Feature StoreGradient-Boosted TreesPythonRegressionSQL
5 Days AgoSaved
Remote
Indianapolis, IN
208K-312K Annually
Senior level
208K-312K Annually
Senior level
Cloud • Legal Tech • Software
Lead a team of ML engineers to design, build, and productionize LLM/GenAI and agentic systems (retrieval, tool use, orchestration). Collaborate cross-functionally with MLOps, product, and data science, review code, mentor engineers, run technical evaluations and proofs-of-concept, and ensure reliable, safe ML deployments for a large SaaS product.
Top Skills: Agentic SystemsEvaluation FrameworksFine-Tuning Foundational ModelsGenaiLlmsMlopsPrompt DesignRag (Retrieval-Augmented Generation)RetrievalTool-Calling AgentsTraining Language ModelsUnstructured Data Preprocessing
5 Days AgoSaved
Remote
Indianapolis, IN
117K-187K Annually
Senior level
117K-187K Annually
Senior level
Edtech
Embed with strategic higher-education partners to design, build, and ship production AI and platform integrations (LLM/RAG, LTI) across Cengage products. Own end-to-end deployments, write production code, ensure compliance and accessibility, evaluate AI safety and outcomes, mentor FDEs, and translate field learnings into product roadmap contributions.
Top Skills: AgsApi GatewayAuroraAWSCaliperCloudwatchCoppaDeep LinkingEcsEksFerpaGraphQLJavaScriptLambdaLlm ApisLti 1.3Lti AdvantageMindtapNrpsPrompt EngineeringPythonRag (Retrieval-Augmented Generation)RdsRestS3SQLTool-Calling AgentsTypescriptWebassignXapi
Reposted 5 Days AgoSaved
Remote
Indianapolis, IN
156K-229K Annually
Senior level
156K-229K Annually
Senior level
Productivity • Software • Conversational AI
The Machine Learning Engineer will develop and maintain scalable ML systems, collaborate across teams, and innovate solutions for real-time applications to enhance customer experiences.
Top Skills: AirflowAWSAzureDockerDynamoDBEmrFlinkGCPJavaKafkaKubeflowKubernetesMetaflowMlflowOpensearchPythonSagemakerSnowflakeSparkSQL
Reposted 14 Days AgoSaved
In-Office or Remote
Indianapolis, IN
Senior level
Senior level
Artificial Intelligence • Computer Vision • Machine Learning • Robotics • Business Intelligence • Automation • Manufacturing
As a Senior Machine Learning Engineer (Tech Lead), you'll lead the ML technical direction, design architectures for loco-manipulation, mentor team members, and manage cross-functional partnerships while writing production-quality code.
Top Skills: C++Python
15 Days AgoSaved
In-Office or Remote
Indianapolis, IN
Senior level
Senior level
Artificial Intelligence • Computer Vision • Machine Learning • Robotics • Business Intelligence • Automation • Manufacturing
Design, implement, and deploy reinforcement learning algorithms for robotic control and motion planning. Integrate RL policies with robot control systems and perception, build sim-to-real pipelines (domain randomization, transfer learning), run large-scale simulation training, and validate models on physical robots while optimizing for embedded compute and safety.
Top Skills: GazeboIsaac GymMujocoPybulletPythonPyTorchTensorFlow
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Reposted 5 Days AgoSaved
Remote
Indianapolis, IN
130K-187K Annually
Senior level
130K-187K Annually
Senior level
Aerospace • Defense • Manufacturing
The job involves building responsive web dashboards, advanced data visualizations, and analytics tools for unmanned aircraft systems, requiring a deep understanding of UI/UX design and data presentation.
Top Skills: AngularCSSD3.JsFigmaGraphQLHTMLJavaScriptJestMobxNumpyPandasPlotlyPythonReactRechartsRestful ApisTypescriptVueWebglZustand
Reposted 5 Days AgoSaved
Remote
Indianapolis, IN
248K-310K Annually
Senior level
248K-310K Annually
Senior level
Real Estate • Travel • PropTech
Responsible for fine-tuning state-of-the-art LLMs, optimizing models for deployment, and driving AI architectural decisions. Collaborate with cross-functional teams to develop impactful AI products.
Top Skills: PythonPyTorch
Reposted 7 Days AgoSaved
Remote
Indianapolis, IN
136K-167K Annually
Senior level
136K-167K Annually
Senior level
Fashion
Design, develop, and maintain scalable ML and AI platform infrastructure for model training, deployment, feature engineering, candidate generation, agent deployment, and observability. Collaborate with data scientists and engineers, support platform operations, drive improvements, codify best practices, and influence platform investments to enable production ML systems at scale.
Top Skills: AnyscaleAWSFastapiGenerative AiGoKafkaLanggraphLangsmithPostgresPythonRayRedis
Reposted 7 Days AgoSaved
In-Office or Remote
Indianapolis, IN
56K-196K Annually
Senior level
56K-196K Annually
Senior level
Agency • Information Technology
Build and scale production-ready generative AI applications: design multi-agent workflows, implement advanced RAG with vector DBs, integrate/swap LLMs, fine-tune models, and deploy scalable FastAPI/Docker services with monitoring and optimization for latency, cost, and reliability.
Top Skills: Async PythonCi/CdClaudeDockerFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm Quantization/HostingModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector Databases
Reposted 7 Days AgoSaved
In-Office or Remote
Indianapolis, IN
44K-154K Annually
Senior level
44K-154K Annually
Senior level
Agency • Information Technology
Design, develop, and deploy machine learning and deep learning models; build end-to-end ML pipelines including preprocessing, training, evaluation, and deployment; perform feature engineering on large datasets; deploy and monitor models on cloud platforms; collaborate with cross-functional teams to integrate AI solutions and retrain models as needed.
Top Skills: AWSAzureCi/CdComputer VisionDockerGCPHadoopKubernetesLlmsNlpPythonPyTorchScikit-LearnSparkSQLTensorFlow
Reposted 7 Days AgoSaved
In-Office or Remote
Indianapolis, IN
50K-177K Annually
Senior level
50K-177K Annually
Senior level
Agency • Information Technology
Operate and monitor ML/AI models and agentic systems in production. Build AI observability, logging, tracing, and evaluation pipelines. Monitor LLM outputs, detect drift and model degradation, and maintain data/feature pipelines. Develop CI/CD, model versioning, experiment tracking, and automate alerts and incident remediation while collaborating with data scientists and platform teams.
Reposted 7 Days AgoSaved
In-Office or Remote
Indianapolis, IN
71K-249K Annually
Senior level
71K-249K Annually
Senior level
Agency • Information Technology
Design, build, and deploy production generative AI applications: orchestrate multi-agent workflows, implement advanced RAG with vector databases, integrate/benchmark LLMs, fine-tune models, and deploy scalable FastAPI-based services with monitoring, CI/CD, and Dockerized production pipelines.
Top Skills: Async PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLlm QuantizationLocal Llm DeploymentModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchRagTensorFlowVector DatabasesVector Search
Reposted 7 Days AgoSaved
In-Office or Remote
Indianapolis, IN
53K-188K Annually
Senior level
53K-188K Annually
Senior level
Agency • Information Technology
Design, build, and deploy production-grade generative AI systems: multi-agent orchestration, advanced RAG with vector databases, integrate/swap LLMs, fine-tune models, optimize prompts and latency, and containerize services with monitoring and CI/CD.
Top Skills: Api SecurityAsynchronous ProgrammingCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLocal LlmsModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchQuantizationRagTensorFlowVector Databases
Reposted 7 Days AgoSaved
In-Office or Remote
Indianapolis, IN
56K-196K Annually
Senior level
56K-196K Annually
Senior level
Agency • Information Technology
Design, build, and deploy production-ready generative AI applications: architect multi-agent workflows, implement advanced RAG with vector DBs, integrate/swap LLMs, fine-tune models, and deliver scalable FastAPI-based services with monitoring, CI/CD, and containerized deployment.
Top Skills: Async PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector DatabasesVector Search
Reposted 7 Days AgoSaved
Remote
Indianapolis, IN
51K-178K Annually
Senior level
51K-178K Annually
Senior level
Agency • Information Technology
Design, implement, and own end-to-end scalable ML systems and MLOps lifecycle (deployment, monitoring, metrics). Optimize models and system performance, work with Java/Python and TF/PyTorch, use CI/CD, Terraform, Docker/Kubernetes, lead inter-team communication, document work, and meet deadlines.
Top Skills: SparkCi/CdDockerGcp Ml Tech StackHadoopInfrastructure As CodeJavaKubernetesPrompt EngineeringPruningPythonPyTorchQuantizationSpeculative DecodingTensorFlowTerraform
Reposted 7 Days AgoSaved
In-Office or Remote
Indianapolis, IN
48K-170K Annually
Senior level
48K-170K Annually
Senior level
Agency • Information Technology
Build and scale production Generative AI applications: design multi-agent systems and LangGraph workflows, implement advanced RAG with vector DBs, integrate and fine-tune LLMs, deploy FastAPI async services in Docker, and optimize GenAI performance, cost, and monitoring.
Top Skills: Api SecurityAsync PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLlm QuantizationLocal Model DeploymentModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector DatabasesVector Search
Reposted 7 Days AgoSaved
In-Office or Remote
Indianapolis, IN
53K-188K Annually
Senior level
53K-188K Annually
Senior level
Agency • Information Technology
Build, optimize, and scale production Generative AI applications. Design multi-agent systems and LangGraph workflows, implement advanced RAG with LlamaIndex and vector DBs, fine-tune and deploy LLMs, and create high-performance FastAPI async backends. Improve latency, cost, and reliability, containerize services with Docker, and manage monitoring, API security, and CI/CD for ML deployments.
Top Skills: Api SecurityAsync PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLlm Quantization/HostingLocal Model DeploymentModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector DatabasesVector Search
Reposted 7 Days AgoSaved
In-Office or Remote
Indianapolis, IN
79K-276K Annually
Senior level
79K-276K Annually
Senior level
Agency • Information Technology
Design, build, and scale production Generative AI applications including multi-agent systems, advanced RAG pipelines, and local/frontier LLM deployments. Implement high-performance backends with FastAPI and async Python, fine-tune and quantize models, integrate vector databases and retrieval systems, and deploy/monitor containerized AI services for reliability, latency, and cost optimization.
Top Skills: Async PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLocal Llm Quantization/HostingModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchRagTensorFlowVector Databases
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