Top Senior Machine Learning Jobs in Indianapolis, IN

Drive go-to-market execution across Nabla’s product portfolio, including positioning, messaging, sales enablement, competitive intelligence, demand-generation partnerships, customer adoption content, and event support. Progress into owning go-to-market strategy for specific products from early definition through launch and adoption, partnering with Product and Engineering and tracking launch success metrics.

The Sr. Machine Learning Engineer will develop and deploy ML solutions for healthcare, manage data pipelines, and work with large datasets to enhance healthcare delivery.

As a Staff Applied ML Scientist, you will develop and maintain fraud detection models, conduct research on fraud types, and collaborate across teams to drive product development and real-time decision-making.

As a Senior Applied ML Scientist, you'll develop fraud detection models, research new fraud types, and write production code while collaborating across teams to enhance SentiLink's identity verification solutions.

Lead end-to-end healthcare analytics projects, managing scope, planning, execution, client relationships, cross-functional collaboration, risks, and delivery. Provide thought leadership in healthcare analytics and identify business opportunities within client accounts. Required capabilities include quantitative analysis, project management, communication, presentation, SQL/Python/R proficiency, and strategic use of AI tools. Preferred experience includes consulting, cloud analytics platforms, healthcare data regulations, predictive modeling, machine learning, and data visualization.

Leads architecture and development of production-grade mapping and localization ML systems for autonomous vehicles. Designs neural models for detection, segmentation, tracking, depth estimation, 3D reconstruction, and semantic mapping; owns data strategy, evaluation, deployment, and fleet validation. Mentors engineers, drives technical roadmaps, collaborates cross-functionally, and advances vectorized HD mapping, foundation models, and real-time optimization.

Own end-to-end design for complex financial product experiences from exploration through launch and iteration. Translate financial workflows into intuitive customer experiences, set high standards for interaction and visual design, partner with product and engineering, use research and data to guide decisions, contribute to design systems, present work clearly, and mentor teammates. Apply AI-enabled tools thoughtfully while maintaining strong human-centered judgment.

Leads an engineering team building and scaling customer-facing integrations for agentic AI products. Responsibilities include setting technical direction, balancing customer delivery with reusable tooling and platform investments, ensuring reliability and observability, improving developer experience, collaborating cross-functionally, recruiting, and coaching engineers. The role requires customer empathy, strong engineering leadership, technical problem-solving, and experience with production systems or integrations.

Develop and optimize large-scale advertising ranking models for CTR and CVR prediction, calibration, user representations, and sequence modeling. Own machine learning systems end to end, including data pipelines, feature engineering, training, evaluation, deployment, and maintenance. Collaborate with platform, product, data science, and engineering teams to run experiments and improve advertiser outcomes, revenue, and user relevance. Apply deep learning and recommendation techniques within production latency, reliability, and cost constraints.

Lead research and experimentation to measure ad campaign performance and effectiveness. Design evaluation frameworks, build measurement solutions, develop models for lift, conversion, and attribution, run experiments and analyses, partner with product/engineering/design/sales, present insights, mentor teammates, and foster technical community and culture.

Build and operate scalable, highly available ML/LLM serving and compute infrastructure. Own long-term platform vision, deliver zero-to-one projects, partner cross-functionally, optimize performance and capacity, and support production ML models at scale.

Design, productionize, and deploy machine learning forecasting models for ad inventory and campaign performance in low-latency, real-time advertising environments. Build scalable simulation, budgeting, and pacing systems; collaborate with cross-functional teams to deploy models at scale and optimize ad monetization.

Lead design, execution, and optimization of scaled lifecycle campaigns across email and in-product channels. Use marketing automation, behavioral data, and ML techniques to personalize journeys, drive activation, revenue, retention, and cross-sell. Analyze performance, generate insights, and collaborate with Growth, Product, Engineering, Data Science, Analytics, Sales, and Marketing stakeholders.

Lead design, execution, and interpretation of A/B tests and quasi-experiments; apply causal inference methods; partner with product, engineering, and marketing; mentor data scientists; build experimentation frameworks; extract and analyze data using SQL and Python; communicate results to stakeholders.

Architect and implement enterprise-grade MLOps/LLMOps platforms on AWS and Kubernetes. Design ML/LLM pipelines for training, validation, deployment, monitoring, governance, CI/CD, and observability. Serve as technical authority, conduct architecture reviews, ensure security and compliance, and mentor engineering teams across projects.

Founding Engineer responsible for building FilmoreAI’s production AI and data platform for construction equipment dealers. The role covers agent infrastructure, model routing, LLM extraction and reasoning, canonical data modeling, entity resolution, Python data pipelines, Azure cloud orchestration, evaluation, observability, and safe human-approved write-back. The engineer will work independently in an ambiguous startup environment and use agentic development tools to ship reliable systems with strong cost, latency, accuracy, and operational guardrails.

Lead the architecture, implementation, governance, and operation of enterprise AI agents using Amazon Bedrock AgentCore. Design agents, knowledge bases, action groups, orchestration workflows, registries, guardrails, and emergency shutdown controls. Guide ECS deployments, API Gateway integrations, IAM governance, authentication, and platform standardization. Provide technical leadership to engineering and DevOps teams while collaborating with AWS specialists, customers, and business stakeholders.

Conduct machine learning research operations using existing infrastructure. Characterize neural network quality, failure modes, and edge cases; coordinate experiments with researchers; manage concurrent experiments and deadlines; review results; recommend theoretical or process improvements; and prepare technical reports communicating qualitative and quantitative findings.

Leads the design, development, deployment, and optimization of generative AI and machine learning solutions. Architects agentic LLM workflows, integrates AI with enterprise systems, performs data engineering and analysis, and applies secure software practices for production deployment. Develops reusable AI frameworks, implements responsible AI controls, communicates technical concepts to stakeholders, and mentors engineers and data scientists. The role requires expertise in LLMs, RAG, prompt engineering, fine-tuning, model evaluation, and AI governance.

The Senior Product Manager will set product direction, own the development lifecycle, collaborate with teams, and ensure high-quality outputs. This role requires strong opinions on product quality and customer insights.

The Enterprise Account Executive drives revenue through high-value contracts, managing complex sales processes and relationships with executive stakeholders in financial services.

Lead the Decision Science function, designing ML models, overseeing experimentation frameworks, and ensuring model adoption across the company, driving operational and commercial improvements.

Build and ship production LLM-powered agents, workflows, and integrations using platform templates, pipelines, and guardrails. Develop comprehensive evaluation suites, integrate business systems and data sources, instrument cost and quality telemetry, and collaborate with business users to iterate within defined scopes. Requires extensive software engineering experience, production LLM application expertise, strong Python and TypeScript skills, API craftsmanship, prompt and context engineering, and a commitment to guardrails and evaluation.

Build and deploy LLM-powered agents, workflows, and integrations using production templates, pipelines, and guardrails. Develop comprehensive evaluation suites, integrate with business systems and data sources, and instrument solutions for cost and quality telemetry. Collaborate with business users to iterate rapidly within defined scopes. The role requires strong Python and TypeScript skills, production LLM application experience, API development, prompt and context engineering, and retrieval expertise.

Develops AI/ML prototypes, APIs, microservices, integrations, and lightweight user interfaces for federal and DoD-aligned mission workflows. The role integrates and optimizes machine learning models for dashboards and applications, supports data ingestion and preprocessing, validates performance, and helps transition models into production. Collaboration with data scientists, architects, developers, PMO leadership, and cybersecurity teams is required. The position requires five years of relevant experience, a bachelor’s degree, ITIL v4 Foundation certification, and Public Trust or active Secret clearance.