Top Senior IT Jobs in Indianapolis, IN

Develop and maintain internal full-stack applications using C#/Blazor or Python. Build CI/CD pipelines and infrastructure automation with GitLab, Azure DevOps, GitHub, Artifactory, and SonarQube. Partner with cross-functional teams to improve software delivery, code quality, security, compliance, and operational visibility. Implement scalable enterprise solutions, infrastructure as code, secure development practices, and DevSecOps workflows.

Leads digital plant applications and infrastructure for a radiopharmaceutical manufacturing site. Oversees MES, LIMS, laboratory and process automation, manufacturing and quality systems, site infrastructure, service levels, disaster recovery, vendor services, regulatory readiness, data integrity, cybersecurity, and technology roadmaps. Partners with engineering, manufacturing, quality, supply chain, automation, architecture, and equipment providers to deliver stable, compliant, commercially scalable solutions.

Leads Engine’s distributed IT organization and modernizes its IT function. Responsibilities include managing engineers and support analysts, improving device lifecycle and endpoint security, architecting Okta-based identity and automation, overseeing onboarding and offboarding, establishing support SLAs, partnering with Security and People teams, reducing technical debt, and delivering cross-functional technology programs. The role is hands-on, combining strategic leadership with technical troubleshooting and execution.

Lead a globally distributed IT engineering team building enterprise integrations, workflow automation, orchestration, and AI-native workflows. Set technical direction, establish roadmaps, manage delivery metrics, and partner with business and service operations leaders to eliminate manual work. Guide engineers on architecture, CI/CD, testing, and development practices while evaluating emerging automation and AI tools. Build integrations across identity, ITSM, SaaS, and enterprise systems, and grow team capabilities across US and India time zones.

Designs, deploys, secures, and supports OT network infrastructure in manufacturing environments. Responsibilities include network architecture, segmentation, IDMZ and firewall implementation, incident escalation, troubleshooting, documentation, project cutovers, maintenance support, and collaboration with IT and plant engineering teams. The role also mentors support personnel and translates production requirements into reliable, high-availability network solutions.

Provides on-site IT support, IT concierge services, ticket resolution, device staging, repairs, workplace setup, asset inventory, and customer service. Supports data center, MDF, and IDF infrastructure through rack-and-stack, cabling, patching, equipment moves, and network troubleshooting. Coordinates with internal teams and vendors, maintains documentation and secure data rooms, supports audits, contributes to process improvement and knowledge management, and participates in on-call rotations.

Leads risk-based audits of bank technology operations, including cloud computing, cybersecurity, network and application security, digital implementation, and data governance. Plans audit scopes, evaluates controls and regulatory compliance, analyzes evidence, documents testing, presents findings, recommends corrective actions, and validates remediation. Requires substantial IT audit, information security, technology risk, and banking experience, plus knowledge of financial services frameworks and enterprise technologies.

Leads enterprise network architecture strategy, roadmaps, design, implementation, monitoring, and maintenance across on-premises, LAN, WAN, SD-WAN, wireless, data center, and AWS/Azure cloud environments. Manages network vendors, carriers, contracts, documentation, budgets, incidents, changes, and infrastructure projects. Provides technical leadership, mentoring, troubleshooting, and on-call support for mission-critical network issues.

Designs, deploys, and documents enterprise, datacenter, wireless, and cloud network architectures for consulting clients. Responsibilities include network assessments, equipment installation, security compliance, performance monitoring, incident resolution, technical documentation, project execution, and mentoring. The role requires extensive routing, switching, firewall, wireless, cloud networking, and network security expertise, along with approximately 25% local and national travel.

Develops, edits, and maintains complex technical documentation for enterprise IT hardware and software. Produces installation, configuration, how-to, implementation, transition, system operations, testing, data flow, and end-user guides. Collaborates with technical teams, revises content for accuracy and clarity, and edits graphics, tables, and illustrations. Requires 5+ years of related experience and an active Secret clearance. This is a remote role with approximately 10% travel.

Provides second-line remote IT support for client end users, resolving escalated Windows, macOS, Microsoft 365, identity, Intune, application, printing, and collaboration issues. Manages onboarding, offboarding, access changes, endpoint deployment, patching, and security compliance. Works within ticket priorities and service-level objectives, documents solutions, creates knowledge articles, identifies recurring problems, and escalates infrastructure issues with detailed troubleshooting information.

Own day-to-day IT and information security operations for a fully remote Mac fleet. Responsibilities include endpoint lifecycle management, identity and access administration, Google Workspace, helpdesk support, asset coordination, CrowdStrike EDR monitoring, DLP controls, Datadog SIEM alerting, security hygiene, access reviews, and SOC 2 and PCI evidence collection. The role requires autonomous ownership, automation, clear documentation, cross-functional collaboration, and approximately 4–6 years of experience beyond ticket-only support.

Develop and maintain AmeriCorps grants management applications using Java, Oracle, PL/SQL, and SQL. Modernize systems, implement enhancements and interfaces, support security and privacy requirements, collaborate with stakeholders to capture and deliver requirements, and perform application testing and maintenance.

Leads large-scale Oracle Cloud Infrastructure migration programs, managing schedules, budgets, risks, dependencies, governance, vendors, stakeholders, and cloud delivery teams. Oversees migration planning and execution for applications, databases, and infrastructure; drives change management, documentation, training, compliance, cost optimization, quality, and operational reporting. The role also supports cloud adoption, partner coordination, and predictable cutovers across multiple initiatives.

Identifies, evaluates, and secures sites for telecommunications network deployment supporting the Army TEN-M program. Manages site leasing, zoning, negotiations, municipal approvals, permits, NEPA and environmental clearances, and regulatory compliance. Coordinates with engineering and operations teams to ensure technical documentation, drawings, and permit applications are complete and submitted accurately. This is a remote role requiring residence within 50 miles of a major airport and 25–50% travel.

Supervises policy and legal affairs contractors while drafting, editing, researching, and reviewing policies, procedures, reports, responses, and executive materials. Coordinates approval processes, FOIA and congressional inquiry responses, interagency reviews, stakeholder communications, document management, and special projects. Oversees staff performance, onboarding, training, deliverables, timecards, reports, and process improvements. Supports research involving child welfare, foster care, mental health, family reunification, and underserved populations.

Designs scalable ETL/ELT pipelines, analytics-ready data models, and executive dashboards using Python, SQL, Tableau, Power BI, and cloud tools. Performs data mining, modeling, validation, documentation, and reporting while collaborating with technical and business stakeholders. Provides mentorship and technical guidance on analytics engineering, workflow automation, and data best practices. The role is fully remote, requires U.S. citizenship, and requires or permits obtaining Public Trust and Top Secret eligibility.

Leads the design, implementation, administration, integration, testing, and enhancement of Veeva Vault RIM. Translates business requirements into functional specifications, manages application roadmaps, supports GxP compliance, oversees internal and external technical resources, and drives system optimization. The role also provides troubleshooting, root-cause analysis, user support, data migration assistance for M&A activities, and technology guidance involving emerging technologies and AI.

Develop data-driven solutions using artificial intelligence, machine learning, predictive modeling, and advanced data analysis. Evaluate data sources, monitor model performance and accuracy, identify business opportunities, and improve customer experience and operational efficiency. Collaborate with stakeholders, interpret application data, communicate findings, and potentially lead teams or mentor less experienced professionals. The role supports USPS, is fully remote, and requires obtaining a Public Trust clearance.

Designs, deploys, maintains, and secures cloud solutions across AWS, Azure, GCP, and OCI. Develops automation using Bash, PowerShell, and Python; monitors and tunes cloud platforms; maintains documentation and operating procedures; advises implementation teams; supports migrations and infrastructure buildouts; resolves escalations; and collaborates with internal and external stakeholders.

Supports governance, monitoring, and IT General Controls for third-party relationships and external users. Responsibilities include due diligence, risk classification, identity and access oversight, least-privilege reviews, access certifications, MFA and DLP monitoring, incident escalation, remediation tracking, audit support, reporting, business continuity and disaster recovery activities, offboarding controls, process documentation, and stakeholder coordination across IT, security, compliance, legal, HR, and vendor management.

Develops and enhances Oracle EBS asset, financial, and logistics modules for Defense Logistics Agency programs. Builds integrations, RICE-FW interfaces, conversions, reports, and automation for capitalization, depreciation, valuation, and accounting processes. Supports testing, troubleshooting, reconciliation, audit traceability, technical documentation, and data mapping. Collaborates with functional SMEs on A2R requirements and process flows while integrating Oracle EBS with external asset and logistics systems.

Leads enterprise IT infrastructure and service operations, overseeing service-level performance, ITSM processes, project intake, business requirements, reporting, budgets, process improvement, escalations, and stakeholder relationships. Develops service delivery plans, manages providers and SLAs, supports healthcare and Medicaid contract compliance, and guides cross-functional initiatives. Hires, mentors, and develops a high-performing IT team while ensuring reliable services, operational efficiency, and alignment with organizational goals.

Supervises monitoring and compliance staff conducting grant-program reviews. Provides technical guidance, coordinates monitoring schedules and site assessments, reviews reports and corrective actions, analyzes compliance trends and risks, and recommends improvements. Oversees staff performance, training, deliverables, timecards, and reporting. Leads on-site and remote reviews, interviews stakeholders, evaluates program data and documentation, identifies technical assistance needs, and communicates findings to federal and recipient staff. Requires frequent domestic travel despite being fully remote.

Supervises project analysts and help desk support staff, overseeing performance, quality assurance, onboarding, training, reporting, and professional development. Manages technical projects, change management activities, IT governance, Scrum meetings, user administration, troubleshooting, and escalation of technical issues. Coordinates with stakeholders and resolver groups, monitors service metrics, maintains support documentation, and ensures timely completion of work plans and project deliverables.