Top Senior Data Science Jobs in Indianapolis, IN

3 Days AgoSaved
Remote or Hybrid
Indianapolis, IN
120K-180K Annually
Senior level
120K-180K Annually
Senior level
Cloud • Computer Vision • Information Technology • Sales • Security • Cybersecurity
Lead research and engineering of production-grade LLM/GenAI systems for cybersecurity: design models and architectures, drive data labeling and evaluation, collaborate with product and engineering to deploy scalable solutions, mentor data scientists, set technical strategy, and advance AI safety, red-teaming, and applied ML innovations for detection and operational use.
Top Skills: Cloud TechnologiesDeep Learning FrameworksGenaiGpu TechnologiesLlmsPython
4 Days AgoSaved
Remote or Hybrid
Indianapolis, IN
149K-187K Annually
Senior level
149K-187K Annually
Senior level
Cloud • Fintech • Information Technology • Machine Learning • Software • App development • Generative AI
Lead advanced analytics and ML efforts to extract insights from large-scale historical data, design features and data representations for models and LLM/agentic systems, partner with product and engineering to build data pipelines and prototypes, evaluate AI workflows, and drive innovation through experiments and empirical analysis to inform product strategy.
Top Skills: Agentic Ai SystemsAws-Native Data And Ml StackBigQueryData PipelinesEmbeddingsFeature EngineeringGCPGraph DatabasesLarge Language Models (Llms)NoSQLRetrieval StrategiesSnowflakeSQLVertex Ai
Reposted 4 Days AgoSaved
Remote
Indianapolis, IN
200K-240K Annually
Senior level
200K-240K Annually
Senior level
Fintech • Information Technology • Software
As a Staff Data Scientist at SentiLink, you will develop fraud detection models, conduct analyses, collaborate across teams, and drive the development of financial risk products.
Top Skills: AWSPostgresPython 3
6 Days AgoSaved
Easy Apply
Remote
Indianapolis, IN
Easy Apply
153K-180K Annually
Senior level
153K-180K Annually
Senior level
Artificial Intelligence • Fintech • Healthtech • Software
Lead product analytics efforts by designing and evaluating experiments, building dashboards, and producing statistical insights. Partner with product, design, and engineering to measure product success, identify optimization opportunities, and embed ML-driven personalization into the product.
Top Skills: DbtHexLookerPythonSQL
Reposted 21 Days AgoSaved
Easy Apply
In-Office or Remote
Indianapolis, IN
Easy Apply
170K-248K Annually
Senior level
170K-248K Annually
Senior level
Healthtech • Information Technology • Mobile • Productivity • Software • Analytics • Telehealth
Lead development and evaluation of AI products for medical professionals using large-scale datasets. Create product and client-facing analytics, influence data team strategy, and collaborate with product managers, analysts, and engineers to execute data projects from ingestion through analysis to recommendations.
Top Skills: Deep LearningDistributed Data Processing ToolsDpoEmacsGitGitLarge Language Model Fine-Tuning (SftPythonPyTorchReinforcement LearningRft)SQLTensorFlowUnixVim
Reposted 12 Days AgoSaved
Remote
Indianapolis, IN
170K-272K Annually
Senior level
170K-272K Annually
Senior level
Cloud • Fintech • Food • Information Technology • Software • Hospitality
Lead design and delivery of scalable ML systems across the full lifecycle for recommendations, demand forecasting, targeting, and personalization. Collaborate with engineers, product, and stakeholders to set architecture, metrics, and production best practices; mentor data scientists; lead experimentation and deploy/monitor models using cloud and MLOps tooling.
Top Skills: AthenaAWSBedrockDistributed Data ProcessingDynamoDBGlueLlm Fine-TuningMlopsPythonPyTorchReal-Time InferenceRlhfSagemakerScikit-LearnSQLTensorFlow
Reposted 12 Days AgoSaved
Easy Apply
Remote
Indianapolis, IN
Easy Apply
236K-295K Annually
Senior level
236K-295K Annually
Senior level
Artificial Intelligence • Enterprise Web • Information Technology • Productivity • Sales • Software • Database
Lead product analytics to inform strategy and optimize user experience: translate business questions into analysis, build reliable analytics infrastructure, run A/B tests and ML/statistical analyses, track funnels and cohorts, support 0-to-1 product launches, and communicate actionable insights to cross-functional teams.
Top Skills: A/B TestingAmplitudeHeapLookerMachine LearningMixpanelPythonRSASSQLStatistical Analysis
13 Days AgoSaved
Easy Apply
Remote or Hybrid
Indianapolis, IN
Easy Apply
160K-194K Annually
Senior level
160K-194K Annually
Senior level
Artificial Intelligence • Insurance • Machine Learning • Software • Analytics
Lead complex modeling projects combining deep learning, LLMs, and traditional techniques. Prototype, deploy, and monitor production models, mentor data scientists, collaborate with engineering/product, and translate results into business impact for insurance customers.
Top Skills: APIsBig DataCi/CdDockerExperiment TrackingFederated LearningGlmJupyterLlmsMlopsModel ServingNeural NetworksPipeline OrchestrationPythonTime Series ModelingTransformersXgboost
22 Days AgoSaved
Hybrid
Indianapolis, IN
99K-232K Annually
Senior level
99K-232K Annually
Senior level
Artificial Intelligence • Professional Services • Business Intelligence • Consulting • Cybersecurity • Generative AI
Lead teams applying advanced data science and machine learning to large-scale claims, clinical, and member data to generate actionable insights that reduce cost of care and improve population health. Manage client relationships, mentor staff, ensure project delivery and quality, develop payer-focused analytics products, present findings to senior stakeholders, and promote continuous improvement and knowledge sharing.
Top Skills: Claims DataClinical DataCms Star RatingsMachine LearningNcqa HedisNlpSocial Determinants Of Health (Sdoh) Data
Reposted 16 Hours AgoSaved
In-Office
Indianapolis, IN
129K-240K Annually
Senior level
129K-240K Annually
Senior level
Healthtech • Biotech • Pharmaceutical
Lead identification and delivery of high-impact data science solutions from concept to production using advanced analytics, machine learning, and deep learning. Collaborate with cross-functional stakeholders, prototype proofs-of-concept, and communicate insights to drive business decisions across Roche Diagnostics.
Top Skills: AWSCloud ComputingData MiningData VisualizationDeep Learning FrameworksDistributed SystemsKanbanMachine LearningPythonRScrumStatistics
4 Days AgoSaved
In-Office
Indianapolis, IN
Senior level
Senior level
Healthtech
Lead predictive modeling and statistical analyses to support member and provider interventions, evaluate care management programs, develop/customize algorithms, process large distributed datasets (e.g., Denodo), score models in batch/real-time, visualize results, and present findings to stakeholders and clients.
Top Skills: BitbucketConfluenceDenodoGitMicrostrategyPower BIPythonRSASSas Enterprise MinerTableau
YesterdaySaved
Remote or Hybrid
Indianapolis, IN
160K-170K Annually
Senior level
160K-170K Annually
Senior level
Artificial Intelligence • Automotive • Computer Vision • Information Technology • Internet of Things • Logistics • Software
Lead evaluation and data strategy for advanced AI, vision, and perception systems. Define metrics, build evaluation frameworks, audit artifacts, prioritize fixes, and translate model behavior into product decisions and data-improvement loops to ensure production readiness and downstream usefulness.
Top Skills: Computer VisionDeep LearningDetectionEvaluation FrameworksGenerative AiGeospatial AiLabel Quality AssessmentMappingMultimodal AiPerception SystemsSegmentationSimulationStructural Similarity (Ssim)Synthetic DataTemporal ConsistencyVideo Quality Metrics
New

Cut your apply time in half.

Use ourAI Assistantto automatically fill your job applications.

Use For Free
Application Tracker Preview
24 Days AgoSaved
Easy Apply
Remote
Indianapolis, IN
Easy Apply
207K-244K Annually
Senior level
207K-244K Annually
Senior level
Artificial Intelligence • Blockchain • Fintech • Financial Services • Cryptocurrency • NFT • Web3
Lead end-to-end pricing experimentation and strategy for consumer and business products. Design and analyze A/B tests, build pricing models and production-grade data pipelines, partner cross-functionally, and present actionable recommendations to senior leadership.
Top Skills: Generative AiPythonRSQL
3 Days AgoSaved
Remote or Hybrid
Indianapolis, IN
140K-215K Annually
Senior level
140K-215K Annually
Senior level
Cloud • Computer Vision • Information Technology • Sales • Security • Cybersecurity
Lead development and deployment of large-scale LLM and GenAI solutions for cybersecurity. Drive research strategy, model training, evaluation, safety/red-teaming, and cross-functional productization. Mentor data scientists, set technical standards, and represent the team through publications and thought leadership.
Top Skills: Cloud TechnologiesDeep Learning FrameworksGenerative AiGpu TechnologiesLlmsPython
Reposted YesterdaySaved
Remote
Indianapolis, IN
Senior level
Senior level
Cloud • Software
Design and deploy predictive forecasting and analytics to support Revenue operations. Build models for forecasting, churn, expansion, and pipeline analytics; create scalable dashboards; partner with Revenue Operations, Finance, and Data Engineering to improve data quality, KPI governance, and executive reporting to drive data-driven decisions and AI readiness.
Top Skills: DashboardsData VisualizationForecastingPredictive AnalyticsPythonSQLStatistical Modeling
Reposted YesterdaySaved
Remote
Indianapolis, IN
Senior level
Senior level
Healthtech
Own end-to-end modeling for vendor matching, order routing, and supply-chain optimization. Build predictive, causal, RL and OR solutions; design autonomous decision logic; quantify counterfactual impact; ship production models with data engineering; mentor senior data scientists; write technical design docs; partner on quarterly priorities and expand into revenue cycle and finance domains.
Top Skills: Agentic AiCausal InferenceCausal MlDiscrete Event SimulationForecastingGitMachine LearningOperations ResearchPythonQueueing TheoryReinforcement LearningSQL
Reposted 2 Days AgoSaved
Remote
Indianapolis, IN
145K-180K Annually
Senior level
145K-180K Annually
Senior level
Healthtech • Telehealth
Senior individual contributor who drives product analytics, experimentation, and applied modeling. Owns growth and performance analyses, designs experiments with robust statistical evaluation, builds repeatable reporting, and partners with Product, Engineering, Operations, Clinical, and Finance to translate data into actionable product and operational decisions.
Top Skills: BigQueryPandasPythonRedshiftScikit-LearnSnowflakeSQLStatsmodels
Reposted 2 Days AgoSaved
In-Office or Remote
Indianapolis, IN
48K-170K Annually
Senior level
48K-170K Annually
Senior level
Agency • Information Technology
Build and scale production Generative AI applications: design multi-agent systems and LangGraph workflows, implement advanced RAG with vector DBs, integrate and fine-tune LLMs, deploy FastAPI async services in Docker, and optimize GenAI performance, cost, and monitoring.
Top Skills: Api SecurityAsync PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringLlm QuantizationLocal Model DeploymentModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector DatabasesVector Search
Reposted 2 Days AgoSaved
In-Office or Remote
Indianapolis, IN
56K-196K Annually
Senior level
56K-196K Annually
Senior level
Agency • Information Technology
Build and scale production-ready generative AI applications: design multi-agent workflows, implement advanced RAG with vector DBs, integrate/swap LLMs, fine-tune models, and deploy scalable FastAPI/Docker services with monitoring and optimization for latency, cost, and reliability.
Top Skills: Async PythonCi/CdClaudeDockerFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm Quantization/HostingModel Fine-TuningMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector Databases
Reposted 2 Days AgoSaved
Remote
Indianapolis, IN
Senior level
Senior level
Agency • Information Technology
Design, build, and deploy machine learning and generative AI models (including LLMs and text-to-image). Analyze large datasets, run A/B and statistical tests, collaborate with data engineering and engineering teams, and create dashboards/visualizations to communicate insights. Optimize data pipelines and model performance to support data-driven decisions.
Top Skills: AWSAzureDall-EGCPGeminiGptLlamaLlmsPower BIPythonPyTorchRScikit-LearnSQLTableauTensorFlow
Reposted 2 Days AgoSaved
In-Office or Remote
Indianapolis, IN
56K-196K Annually
Senior level
56K-196K Annually
Senior level
Agency • Information Technology
Design, build, and deploy production-ready generative AI applications: architect multi-agent workflows, implement advanced RAG with vector DBs, integrate/swap LLMs, fine-tune models, and deliver scalable FastAPI-based services with monitoring, CI/CD, and containerized deployment.
Top Skills: Async PythonCi/CdClaudeDockerEmbedding ModelsFastapiGeminiHugging FaceLangchainLanggraphLlamaLlamaindexLlm MonitoringMulti-Agent SystemsOpenaiPostgresPrompt EngineeringPythonPyTorchTensorFlowVector DatabasesVector Search
8 Days AgoSaved
Remote
Indianapolis, IN
192K-228K Annually
Senior level
192K-228K Annually
Senior level
Healthtech • Social Impact • Software • Telehealth
Owner of analytics for EHR, revenue cycle, and operations: design and run experiments, analyze financial and operational metrics, investigate billing and account issues, and deliver actionable insights to Product, Operations, Finance, and Customer Experience to improve accuracy, reduce friction, and support growth.
Top Skills: EhrHexLookerPythonRevenue Cycle ManagementSQLTableau
Reposted 12 Days AgoSaved
In-Office
Indianapolis, IN
126K-244K Annually
Senior level
126K-244K Annually
Senior level
Healthtech • Biotech • Pharmaceutical
The Data Scientist will lead the development of data products that enable AI-driven insights, ensuring compliance and optimizing processes across CMC workflows.
Top Skills: AirflowAws S3AzureDatabricksGlueLambdaMicrosoft FabricPythonRdsSQL
Reposted 4 Days AgoSaved
Remote
Indianapolis, IN
120K-140K Annually
Senior level
120K-140K Annually
Senior level
Healthtech
Designs, analyzes, and interprets clinical trial, RWE, and observational data for a medical device. Develops statistical plans, predictive models, and ensures data quality, regulatory compliance, and traceability. Collaborates with clinical, regulatory, and data teams, supports submissions and publications, mentors interns, and represents the company externally.
Top Skills: CdiscMl/AiPythonPython DashRR ShinySASSpotfireTableau
Reposted 4 Days AgoSaved
Remote
Indianapolis, IN
170K-220K Annually
Senior level
170K-220K Annually
Senior level
Healthtech • Other • Telehealth
Design, implement, and maintain marketing inference models (e.g., MMM and attribution). Analyze large datasets and A/B/uplift experiments with rigorous statistics, build predictive and causal models, partner with marketing to generate testable ideas, and communicate insights to drive marketing decisions.
Top Skills: PythonRSQL
All Filters
JobType
New Jobs
Job Category
Experience
Industry
Company Name
Company Size

Sign up now Access later

Create Free Account