Top Senior Machine Learning Jobs in Indianapolis, IN

Lead statistical measurement and client intelligence initiatives using healthcare, prescription, and claims data. Develop performance benchmarks, evaluate program impact, apply statistical and machine learning methods, advise data scientists, support survey-based measurement, manage analytics vendors, mentor analysts, and present findings to marketing teams and clients. The role requires advanced SQL and Python, healthcare data expertise, vendor management, and extensive quantitative experience.

Leads client-facing generative AI and data modernization engagements, directing solution design, delivery planning, architecture, and technical decisions. Guides teams in prompt engineering, context engineering, agent orchestration, LLM evaluation, RAG, vector databases, and AI guardrails. Oversees cloud AI implementations using Gemini, Vertex AI, AWS Bedrock, or Azure AI Services; develops Python prototypes; evaluates model performance; manages workstreams and deliverables; and mentors staff on AI methods, agile delivery, and technical problem-solving.

Leads engineering teams delivering scalable AI and machine learning solutions on Google Cloud. Oversees generative AI architecture, Vertex AI, LangChain, LangGraph, LLM APIs, RAG, experimentation, evaluation, guardrails, and LLMOps. Guides technical strategy, client alignment, delivery execution, and team development while applying Python, data science, and machine learning methods to build reliable AI products.

Leads Google Cloud AI and machine learning engineering teams and client workstreams. Oversees generative AI, LLM application, agent orchestration, retrieval-augmented generation, model evaluation, prompt engineering, guardrails, and LLMOps initiatives. Reviews architecture, code quality, testing, and solution delivery using Vertex AI, LangChain, LangGraph, Python, and LLM APIs. Coaches team members, improves reusable delivery assets, and manages client relationships, timelines, quality, and expectations.

Leads client-focused generative AI and data modernization architecture, translating business needs into scalable solutions using Google Cloud, Vertex AI, LLMs, vector databases, and modern data platforms. Advises stakeholders, develops AI evaluation and guardrail practices, guides experimentation and deployment, presents technical recommendations, supports proposals, and coaches teams through complex transformation programs.

Develop and optimize full-funnel, multi-channel demand generation campaigns that generate pipeline, accelerate deals, and support cross-sell and upsell opportunities. Partner with product marketing, sales development, content, product, field, partner marketing, and analytics teams. Build lead-nurturing programs, align assets to buyer stages, monitor conversion and ROI metrics, and create dashboards to optimize campaign performance.

Develop and implement AI solutions and machine learning systems that enhance products and solve complex client problems. Responsibilities include advanced analytics, LLM production deployment, prompt engineering, RAG pipeline optimization, cross-functional collaboration, technical discovery, responsible AI advocacy, client relationship building, and mentoring junior team members.

Develops compliance analytics for AML, sanctions, and consumer compliance programs. Builds data pipelines, dashboards, scorecards, automated reporting, and data quality processes using dbt, GitLab, Python, SQL, Tableau, and Snowflake. Translates regulatory requirements into actionable insights, risk indicators, and metrics while communicating findings to senior management and regulatory stakeholders.

Leads pricing and revenue data science initiatives for consumer markets clients. Develops predictive models, forecasts trends and customer behavior, manages dashboards and visualizations, ensures data quality, and translates complex analytics into strategic decisions. Oversees client engagements, validates outcomes, directs complex projects, and coaches diverse, high-performing teams.

Lead go-to-market strategy for Sprout Social’s AI portfolio, including the Trellis AI agent. Develop enterprise launch playbooks, positioning, executive messaging, campaigns, and enablement programs. Analyze market and competitive dynamics, influence product roadmaps, improve launch processes, and partner with Product, Sales, Revenue, Brand, and executive leadership to drive adoption, revenue growth, deal expansion, and category leadership. The role also mentors marketing team members and operates with substantial autonomy.

Lead agile design and development projects for mobile apps and digital products. Coordinate product, design, engineering, marketing, leadership, and client stakeholders; manage project plans, scope, requirements, backlogs, acceptance criteria, deadlines, workflows, and deliverables. Support scoping and client relationship management while ensuring successful end-to-end software launches and alignment with business objectives.

Lead AI engineering teams to design, build, and deploy end-to-end AI solutions. Manage client relationships, plan and deliver projects, mentor staff, drive adoption of cloud-native microservices, CI/CD, vector databases and orchestration tools, and ensure high standards of quality, innovation, and compliance.

Develop and operate production ML and AI systems powering patient experiences such as matching, ranking, recommendations, onboarding, and personalization. Build reusable ML infrastructure, pipelines, evaluation, observability, and model-serving capabilities. Provide technical leadership across the ML lifecycle, guide architecture, evaluate custom versus foundation-model approaches, and partner with ML and Patient Engineering teams to deliver reliable, scalable AI products.

Develop and deploy reliable machine learning, LLM-powered agent, and agentic workflow systems for government and enterprise customers. Integrate models with tools, APIs, MCP servers, and data sources; build evaluation frameworks for performance, reliability, and safety; improve Chariot, the company’s AI operations platform; and support mission-critical deployments. Collaborate with data scientists, software engineers, DevOps teams, and customers in secure government environments.

Develop and deploy reliable machine learning, LLM, agentic, and data-centric systems for government and enterprise customers. Build and evaluate AI agents, workflows, tool integrations, and retrieval-augmented systems; measure performance, reliability, and safety; and improve the Chariot AI operations platform. Collaborate with customers, data scientists, software engineers, and DevOps teams on mission-critical deployments. The role is fully remote or hybrid in Austin, with travel up to 20%.

Leads the AI Engineering team across applied AI features and foundational ML infrastructure. Responsibilities include managing Senior and Staff engineers, hiring and coaching, deploying LLM-powered capabilities, building MLOps and AI observability platforms, balancing product delivery with platform investment, and ensuring privacy, compliance, evaluation rigor, and clinical safety in production systems.

Own the strategic vision and roadmap for Coursera’s AI-driven search experience. Lead conversational search, personalization, semantic and multilingual search, ranking, and discovery improvements. Partner with engineering, design, research, data science, ML, marketing, and partnerships teams to deliver scalable platform capabilities. Use experimentation, market analysis, KPIs, and customer insights to improve conversion, merchandising, learner experience, and revenue.

Set the technical vision for data science, lead complex statistical and machine learning model development from concept through production, and architect scalable modeling platforms and pipelines. Develop credit risk, pricing, and loss forecasting models; establish model governance standards; partner with senior leaders; mentor data scientists; and communicate technical strategy to executives. The role emphasizes production deployment, monitoring, cloud architecture, and high-impact decision-making across the business.

Design and build maintainable data pipelines, ETL processes, and data architecture standards. Collaborate with product managers, analysts, and machine learning engineers to translate requirements into automated, scalable solutions. Apply software engineering best practices, asynchronous systems, APIs, streaming, testing, monitoring, and Python and SQL expertise. Help prioritize data initiatives based on business impact and communicate complex technical concepts to technical and non-technical stakeholders.

Develop and maintain production machine learning models, build scalable training and serving technologies, optimize real-time and batch ML pipelines, and monitor model performance and drift. The role involves deep neural networks, recommendation systems, automated retraining, ML research, engineering excellence, and communicating technical concepts to diverse audiences. Candidates need 6+ years of industry ML experience, strong coding skills, and experience deploying neural networks at scale.

Leads statistical strategy for complex clinical, diagnostic, translational, and evidence-generation studies. Designs analyses, endpoints, sample sizes, and statistical methodologies; evaluates diagnostic performance and complex clinical and genomic datasets; supports regulatory submissions and scientific communications; establishes statistical standards; reviews analytical work; and mentors statisticians and cross-functional partners.

Designs secure, scalable cloud-enabled architectures for AI-assisted modernization of legacy Marine Corps systems. Advises customers and technical teams, recommends AI/ML, data, cloud, and DevSecOps patterns, manages technical risks, and builds hybrid deterministic-agentic pipelines using LangChain and LlamaIndex. The role also fine-tunes large language models, integrates code-as-data techniques such as ASTs and control/data flow graphs, and develops production AI systems using Java, Python, APIs, and Databricks.

Product Counsel will advise product, engineering, data science, marketing, compliance, and sales teams throughout the product lifecycle. Responsibilities include counseling on regulatory compliance, privacy, intellectual property, consumer protection, AI and machine learning, data rights, platform architecture, APIs, identity and account security, and marketing. The role translates legal requirements into technical guidance, supports AI governance, monitors evolving laws, and develops scalable legal processes for a fast-paced technology company.

Design, build, and support high-throughput, low-latency LLM inference and data pipelines; collaborate with data scientists to post-train and evaluate models; implement scalable, production-ready systems with strong testing, monitoring, and performance focus; mentor engineers and iterate on architecture, reliability, and user-facing AI applications.

Own and maintain product marketing collateral for an AIOps platform, agentic AI orchestrator, and vertical solutions. Translate technical input from product and data science teams into polished presentations, graphics, diagrams, and decision-ready materials. Align messaging with Communications, support government and industry conference operations, develop technical content, and track customer feedback, market trends, competitors, and emerging technologies. The role requires credible communication with technical evaluators and senior government decision-makers.