Top Senior Python Jobs in Houston, TX

Manage identity and access systems, Windows and macOS endpoints, AWS infrastructure, SaaS integrations, networking, automation, and security controls. Build Python, PowerShell, and Bash automations, support compliance readiness, investigate security alerts, maintain audit documentation, and serve as a tier-three escalation point. Lead IT upgrades, system rollouts, troubleshooting, and continuous improvement while translating business needs into secure technical solutions.

Lead design, development, and maintenance of CLA's application frameworks and developer platform. Own CI/CD, release automation, IaC, container patterns, monitoring, and tooling. Mentor developers, enforce standards, conduct code reviews, troubleshoot integrations, and drive framework engineering strategy to enable reliable, repeatable deployments across environments.

Lead architecture, design, and development of core application frameworks. Collaborate with cross-functional teams, enforce coding standards, conduct code reviews, mentor developers, troubleshoot integrations, evaluate new technologies, document designs, and manage team velocity, risks, and CI/CD/tooling for stable framework delivery.

Leads complex production issue resolution, root-cause analysis, reliability improvements, system integrations, and operational automation across factory, cloud, and enterprise environments. Builds AI- and LLM-enabled capabilities for troubleshooting, incident response, knowledge management, and engineering productivity. Partners with Engineering, Manufacturing, Operations, Product, and Customer Success teams to improve scalability and reduce recurring incidents.

Leads full-stack software engineering for market risk, model risk, and treasury technology. Responsibilities include designing, developing, testing, debugging, and operating secure, scalable applications; providing technical direction; governing AI-assisted engineering practices; validating AI outputs for security and correctness; improving SDLC automation; and serving as a subject matter expert across engineering teams.

Designs, develops, tests, and supports embedded electronic instrumentation for the natural gas utility industry. Responsibilities include embedded firmware, analog and digital electronics, PCB design, sensing, simulations, product verification, manufacturing transfer, compliance, troubleshooting, supplier collaboration, and technical mentoring. This hands-on Houston-based role supports products throughout the full development lifecycle and requires up to 20% domestic travel.

Leads investigation and resolution of complex production issues across applications, APIs, cloud services, integrations, data pipelines, and factory systems. Designs factory-to-cloud integrations, develops automation, performs root-cause analysis, improves reliability, and applies AI and LLM technologies to troubleshooting and operational efficiency. Partners with engineering, manufacturing, operations, product, and customer success teams to resolve high-impact problems and reduce recurring incidents.

Provides onsite technical expertise for HPE networking products, including network design, troubleshooting, break/fix support, testing, automation, documentation, and Junos configuration guidance. The role supports customer environments, evaluates engineering designs, drives technology integration, collaborates with internal and external teams, and mentors junior staff. Requires strong data center networking experience, Python scripting, analytical skills, and up to 10% travel.

Provides onsite technical expertise for HPE networking products, including design, troubleshooting, break/fix support, testing, automation, documentation, and Junos configuration. The role supports customer networks, evaluates engineering designs, contributes to cross-organizational projects, mentors junior staff, and advises on best practices. Requires extensive data center routing, switching, and network architecture experience, Python scripting skills, and up to 10% travel.

Develop and test embedded flight software for NASA’s Orion crewed spacecraft. Responsibilities include C/C++ implementation, unit and integration testing, software verification, defect resolution, troubleshooting, software integration, flight software load builds, code reviews, and development of supporting tools and scripts. The role collaborates with NASA and contractor experts while following safety-critical aerospace software processes.

The Senior Developer designs, develops, integrates, and optimizes laboratory information management systems and related applications. Responsibilities include building LIMS modules, APIs, data pipelines, and system interfaces; managing data migration and quality assurance; developing tests; troubleshooting complex issues; supporting UAT and escalated incidents; maintaining technical documentation; ensuring regulatory and data integrity compliance; and mentoring junior developers. The role collaborates with business analysts, QA, laboratory staff, IT, and external vendors, with occasional travel required.

Develop and troubleshoot production firmware, drivers, and embedded software for robotic and electromechanical systems. Responsibilities include hardware bring-up, motor and sensor integration, board testing, requirements translation, firmware deployment, documentation, and debugging. The role collaborates with electrical engineers and technicians and may support spaceflight, avionics, radiation-hardened electronics, and field integration. Travel may be required for assembly, testing, and integration.

Develops and troubleshoots firmware, drivers, and embedded software for robotic and electromechanical systems. Responsibilities include hardware bring-up, board integration, testing, requirements translation, firmware deployment, and collaboration with electrical engineers and technicians. The role involves embedded C/C++ and Python development, real-time systems, robotics integration, communication protocols, automated testing, and debugging using electronics tools. Travel may be required to support hardware assembly, testing, and integration.

Owns complex hybrid-cloud infrastructure operations across data centers, private and public clouds. Administers Linux and Windows systems, virtualization, networking, storage, backup, security, and monitoring. Develops production automation with Ansible, Terraform, Bash, Python, Git, and APIs; leads incident response, root-cause analysis, infrastructure changes, migrations, and modernization. Reviews engineering work, improves operational processes, documents standards, supports escalations, and provides technical guidance. The role includes on-call support, after-hours incident response, and up to 10% travel.

Designs, builds, and maintains full-stack web applications, ERP and CRM integrations, REST APIs, and customer-facing platforms. Develops React interfaces and Python Flask or .NET backend services, manages Microsoft SQL Server databases, integrates Power BI reporting, and maintains CI/CD pipelines. The role also addresses production issues, system performance, security, reliability, code reviews, and architectural planning.

Leads site reliability engineering initiatives for enterprise applications and platforms, improving reliability, scalability, performance, security, observability, and service levels. Acts as the primary technical contact during major incidents, drives SLI/SLO and error-budget practices, reduces toil, mentors engineers, and promotes knowledge sharing. Evaluates enterprise-approved AI capabilities for incident response and reliability workflows while enforcing validation, auditability, data-sensitivity, resiliency, and security controls.

Leads full-stack software engineering within JPMorgan Chase’s supply chain technology team. Responsibilities include designing, developing, testing, debugging, and maintaining secure, scalable production systems; advancing AI-assisted engineering practices; automating recurring issue remediation; ensuring application resiliency and security; and evaluating vendor and internal technology solutions. Requires strong software development, cloud-native, agile, financial-services technology, and responsible AI expertise.

Plans, designs, executes, and documents mechanical and electromechanical tests in industrial laboratory environments. Develops fixtures, methods, instrumentation, and test procedures; collects and analyzes experimental data; validates measurement methods; evaluates materials and system performance; and communicates findings through technical reports and presentations. The role may also involve client interaction, project leadership, troubleshooting, mentoring, and work across aerospace, transportation, energy, industrial, and other safety-critical applications.

Leads Esri Enterprise GIS implementations and defines physical technical solutions. Manages geospatial data strategies, solution configuration, Enterprise GIS installation, administration, troubleshooting, optimization, and deployment across on-premises, AWS, and Azure environments. Oversees geospatial requirements analysis, technology evaluations, data modeling, and implementation deliverables. Requires advanced ArcSDE, ArcGIS Enterprise, geospatial data, Python, FME, and generative AI expertise.

Partners with stakeholders to gather requirements and deliver Salesforce and SiteTracker solutions. Configures platform objects, workflows, permissions, automation, and integrations; develops Apex, Lightning Web Components, Visualforce, and SOQL solutions. Supports solution design, testing, deployment, production troubleshooting, root-cause analysis, and continuous platform improvement while collaborating with Business, QA, and Development teams.

Lead enterprise B2B integration projects for strategic customers using APIs, webhooks, connectors, cloud services, and scalable integration architectures. Translate business requirements into technical designs, build and review code, manage complex projects, troubleshoot deployments, and advise customers and internal teams on integration best practices. Collaborate with product, sales, support, and developer ecosystem teams while supporting multiple customer engagements and improving professional services methodologies.

Leads the design, development, integration, testing, and optimization of laboratory information management systems and related applications. Develops APIs, data pipelines, interfaces, and integrations with laboratory instruments and enterprise systems. Provides technical leadership, mentors developers, troubleshoots complex issues, supports testing and escalated incidents, maintains documentation, and ensures regulatory, audit, security, and data integrity compliance.

Build and maintain onboard and platform software for autonomous mining vehicles, including sensor drivers, data pipelines, synchronization, calibration, deployment, monitoring, simulation, testing, drive-by-wire integration, low-level controls, and safety systems. Collaborate with machine learning, hardware, controls, and mine operations teams through field validation on real equipment.

Own Mariana Minerals’ infrastructure platform across AWS, EKS, on-premises, and edge clusters. Build self-service infrastructure, GitOps delivery, observability, identity and secrets management, cost controls, and reliable ML/data workloads. Lead cluster operations, incident response, upgrades, and automation that enables engineers to provision and operate services independently.

Design, implement, automate, govern, and support enterprise Azure infrastructure and shared cloud services. Build Terraform modules and deployment workflows, administer Entra ID, strengthen security and governance, manage networking and platform services, and troubleshoot complex production issues. Collaborate with infrastructure, security, networking, application, and data teams while documenting standards, supporting continuity, contributing to architecture roadmaps, and mentoring junior engineers. This is a full-time, on-site contractor role in Houston.