Top Senior Software Engineer Jobs in Buffalo, NY

Manage and functionally lead an 8-10 person software engineering team: performance assessments, staffing, development, mentoring, and personnel actions. Provide technical leadership across software lifecycle, ensure high quality delivery, coordinate with stakeholders, and support program and functional responsibilities while maintaining required security clearance.

As a Senior Principal Engineer, you'll define and drive the technical strategy for customer experience platforms, lead architectural decisions, and mentor engineering teams to enhance customer and agent experiences.

Lead the technical vision and architecture for backend systems supporting experimentation, personalization, analytics, and conversion optimization. Design and operate high-throughput distributed systems and APIs, build data infrastructure, and productionize AI/ML capabilities. Drive complex multi-team initiatives, influence engineering strategy, establish technical standards and operational excellence, and mentor senior engineers. Partner with product, data science, ML, and engineering teams to translate business needs into scalable solutions.

Join Archy as a Senior Platform Software Engineer to enhance dental practice management through a scalable SaaS solution, focusing on cloud infrastructure, CI/CD pipelines, and AI integration.

Leads the Bioinformatics Software Engineering team and owns engineering strategy, architecture, delivery, modernization, and production support for clinical genomics platforms. Oversees software engineers, bioinformatics workflows, data integration, automation, quality systems, release governance, reliability, and regulatory compliance. Partners with clinical, laboratory, scientific, quality, product, operations, and executive stakeholders to convert research methods into validated production workflows. Guides AI-enabled engineering initiatives while ensuring privacy, traceability, clinical-grade quality, and operational resilience.

The Staff Software Engineer will shape technical direction, build developer platforms, and design AI agents, enhancing developer productivity and collaboration across teams.

Design, build, and operate scalable, secure data platform infrastructure for ingesting, processing, cataloging, and accessing petabytes of data. Improve Spark/Databricks reliability and developer experience, build ingestion/replication systems, develop internal libraries and tooling (Go/Python), and collaborate with cross-functional teams to support analytics, ML, and customer-facing data products.

As a Senior Software Engineer, you will design and build a cutting-edge identity search platform and implement AI systems for defense applications, working closely with cross-functional teams to enhance user workflows and support national security.

As a Software Development Engineer in Test, you'll create and conduct automated tests, resolve technical issues, and collaborate with development teams to ensure software quality.

The Staff Software Engineer will lead technical strategy, ensure system availability, and develop backend systems at scale, collaborating across teams to drive capacity modeling and operational quality.

As a Senior Software Engineer, you will design and maintain systems, mentor team members, and improve both code quality and team practices.

Lead frontend development using React and TypeScript to design scalable frontend architecture, components, and developer workflows. Own feature delivery from concept to launch, improve CI/CD and testing, collaborate with backend on APIs, evaluate new technologies, and mentor other engineers while ensuring performance, accessibility, and reliability across web surfaces.

Lead architecture and implementation for a secure distributed data platform runtime. Design Go-based concurrency, subprocess supervision, inter-service protocols, distributed persistence, and resilient processing pipelines. Debug complex cross-process and network issues, define testing standards, conduct end-to-end integration and resilience testing, participate in on-call rotations, and lead incident post-mortems. Collaborate with product, engineering, and customer stakeholders to refine requirements and deliver production-ready capabilities. Requires up to 25% international travel to the Middle East.

Modernize and maintain a large-scale React Native mobile app with offline-first architecture, BLE device integrations, data synchronization, and performance improvements. Influence architecture, mentor developers, collaborate across teams, and occasionally visit customer farms to understand workflows.

Build full-stack features and infrastructure analytics products to improve Netflix's cloud and AI efficiency. Design frontends (React/TypeScript), backend services/APIs (GraphQL/Node), shape data models, collaborate with analytics and data engineers, and own product direction from design through implementation.

Modernize and evolve a large-scale React Native mobile app with offline-first architecture, BLE device integrations, local data storage and sync. Improve performance, reliability, and scalability, influence architecture, mentor developers, collaborate cross-functionally, and occasionally visit farms to understand user workflows.

Design, build, and scale highly available backend and frontend systems powering Coinbase trading experiences for millions of users. Architect extensible support for multiple trading types and assets, evolve critical production infrastructure, partner with product and design, and promote engineering quality through code reviews, mentorship, and knowledge sharing.

Design and implement Kotlin backend services and end-to-end systems for Toast POS device management. Lead technical designs, estimations, performance optimization, cross-team collaboration, and software quality practices including modern testing and observability. Mentor peers and drive product roadmap alignment with product, hardware, and QA stakeholders.

Lead and deliver quarterly goals for a backend team; guide engineers through ambiguous problems; collaborate with product, design, and analytics; identify and resolve project and technical issues; ensure operational availability and on-call readiness; set code and design quality standards; and mentor and develop team members.

The Senior Backend Software Engineer will design and scale backend systems using Python and FastAPI, collaborate with researchers, optimize infrastructure, and implement testing and monitoring systems.

Lead the development of analytics infrastructure for clinical AI/ML products, focusing on product performance monitoring, data management, and cross-functional collaboration.

The AI Assisted Software Engineer will design and develop enterprise software solutions, utilizing AI-assisted tools, and architect scalable systems while collaborating across teams to improve business operations.

The Senior Bilingual Software Engineer will align U.S. teams with the Platform Core team in Japan, focusing on high-impact problems and maximizing platform leverage through clear communication and collaboration.

The Backend Software Engineer will develop and maintain backend systems for data processing related to coffee farming, utilizing Python and PostgreSQL. Responsibilities include feature development, problem-solving, and adapting systems to regulatory changes while ensuring system resilience.

Develop and enhance software solutions for mineral exploration, collaborating with geologists and data scientists, and driving insights from data systems.